NO20091101L - Farmasoytisk formulering inneholdenede fenylamidin derivativ og anvendelsesmetode for farmasoytisk formulering i combinasjon med en antifungal agent - Google Patents

Farmasoytisk formulering inneholdenede fenylamidin derivativ og anvendelsesmetode for farmasoytisk formulering i combinasjon med en antifungal agent

Info

Publication number
NO20091101L
NO20091101L NO20091101A NO20091101A NO20091101L NO 20091101 L NO20091101 L NO 20091101L NO 20091101 A NO20091101 A NO 20091101A NO 20091101 A NO20091101 A NO 20091101A NO 20091101 L NO20091101 L NO 20091101L
Authority
NO
Norway
Prior art keywords
pharmaceutical formulation
combination
phenylamidine derivative
antifungal agents
antifungal agent
Prior art date
Application number
NO20091101A
Other languages
English (en)
Inventor
Hiroshi Nishikawa
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of NO20091101L publication Critical patent/NO20091101L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4465Non condensed piperidines, e.g. piperocaine only substituted in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4453Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Et farmasøytisk preparat omfattende et fenylamidin derivat eller et salt derav, representert ved generell formel, hvor Rog Rkan være like eller forskjellig og representerer en eventuelt substituert C_alkylgruppe; og ett eller flere midler valgt fra azol antisoppmidler, polyen antisoppmidler, candin antisoppmidler og fluorpyrimidin antisoppmidler og en metode for kombinasjonsanvendelse av fenylamidin derivatet eller et salt derav og midlene er anvendelige for behandling av soppinfeksjoner forårsaket av et sopp-patogen.
NO20091101A 2006-10-06 2009-03-13 Farmasoytisk formulering inneholdenede fenylamidin derivativ og anvendelsesmetode for farmasoytisk formulering i combinasjon med en antifungal agent NO20091101L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006274709 2006-10-06
PCT/JP2007/069341 WO2008044562A1 (fr) 2006-10-06 2007-10-03 Composition pharmaceutique contenant un dérivé de phénylamidine et procédé d'utilisation de la composition pharmaceutique combinée à un agent antifongique

Publications (1)

Publication Number Publication Date
NO20091101L true NO20091101L (no) 2009-04-27

Family

ID=39282771

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20091101A NO20091101L (no) 2006-10-06 2009-03-13 Farmasoytisk formulering inneholdenede fenylamidin derivativ og anvendelsesmetode for farmasoytisk formulering i combinasjon med en antifungal agent

Country Status (21)

Country Link
US (1) US8173157B2 (no)
EP (1) EP2070536B1 (no)
JP (1) JP5132569B2 (no)
KR (1) KR101409258B1 (no)
CN (1) CN101522195B (no)
AT (1) ATE538789T1 (no)
AU (1) AU2007305626B2 (no)
BR (1) BRPI0719157A2 (no)
CA (1) CA2664915C (no)
CY (1) CY1112617T1 (no)
DK (1) DK2070536T3 (no)
ES (1) ES2376130T3 (no)
MX (1) MX2009003533A (no)
NO (1) NO20091101L (no)
NZ (1) NZ575714A (no)
PL (1) PL2070536T3 (no)
PT (1) PT2070536E (no)
RU (1) RU2429843C2 (no)
SI (1) SI2070536T1 (no)
WO (1) WO2008044562A1 (no)
ZA (1) ZA200902053B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI385169B (zh) 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd 經雜環取代之吡啶衍生物及含有彼之抗真菌劑
TW200841879A (en) 2007-04-27 2008-11-01 Eisai R&D Man Co Ltd Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same
TWI395735B (zh) * 2007-07-04 2013-05-11 Toyama Chemical Co Ltd 4-{3-〔4-(3-{4-〔胺基(丁氧基羰基亞胺基)甲基〕苯氧基}丙基)-1-哌啶基〕丙氧基}-n’-(丁氧基羰基)苄脒之新穎結晶
EP2636409A1 (en) 2010-11-05 2013-09-11 Eisai R&D Management Co., Ltd. Combined pharmaceutical composition as antifungal agent
JP6181044B2 (ja) 2012-04-20 2017-08-16 エーザイ・アール・アンド・ディー・マネジメント株式会社 カプセル剤
DK3532057T3 (da) 2016-10-31 2023-02-20 Biocryst Pharm Inc Prodrugs af kallikreininhibitorer

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4782059A (en) * 1986-09-29 1988-11-01 Merck & Co., Inc. Method of controlling mycotic infections and compositions therefor
JPH03288051A (ja) 1990-03-30 1991-12-18 Mazda Motor Corp カムシャフトおよびその製造方法
GB9509631D0 (en) 1995-05-12 1995-07-05 Sandoz Ltd Antifungal combination
EA002469B1 (ru) * 1996-09-12 2002-06-27 Мерк Энд Ко., Инк. Способ лечения грибковой инфекции
AUPQ066399A0 (en) * 1999-05-31 1999-06-24 Fujisawa Pharmaceutical Co., Ltd. Antifungal combination use
SI1481966T1 (sl) 2002-03-06 2011-11-30 Toyama Chemical Co Ltd Nov derivat arilamidina ali sol le-tega
JP4937506B2 (ja) 2003-09-05 2012-05-23 富山化学工業株式会社 新規なアリールアミジン誘導体またはその塩
WO2005026323A2 (en) 2003-09-05 2005-03-24 Merck & Co., Inc. Stationary phases and a purification process using the stationary phases
KR101169694B1 (ko) * 2004-06-30 2012-07-31 토야마 케미칼 컴퍼니 리미티드 신규의 아릴아미딘유도체 및 그 염과 그들을 함유하는 항진균제
CN1596897A (zh) 2004-07-26 2005-03-23 范敏华 一种伊曲康唑注射剂及其制备方法
JP5021308B2 (ja) 2004-07-28 2012-09-05 富山化学工業株式会社 新規なアリールアミジン誘導体およびその塩ならびにそれらを含有する抗真菌剤
RU2396955C2 (ru) * 2005-04-07 2010-08-20 Тояма Кемикал Ко., Лтд. Фармацевтическая комбинация и способ применения противогрибкового средства в комбинации
WO2007055197A1 (ja) 2005-11-09 2007-05-18 Toyama Chemical Co., Ltd. 4-(3-(4-(3-(4-シアノフェノキシ)プロピル)-1-ピペリジニル)プロポキシ)ベンゾニトリルの製造法およびその中間体
DE602006016010D1 (de) 2005-12-29 2010-09-16 Toyama Chemical Co Ltd Neues arylamid-derivat, salz davon und diese enthaltendes antimykotisches mittel

Also Published As

Publication number Publication date
DK2070536T3 (da) 2012-04-10
CN101522195B (zh) 2012-01-18
EP2070536B1 (en) 2011-12-28
EP2070536A4 (en) 2010-02-10
ZA200902053B (en) 2010-07-28
RU2429843C2 (ru) 2011-09-27
RU2009117207A (ru) 2010-11-20
BRPI0719157A2 (pt) 2014-02-04
CA2664915C (en) 2014-01-07
SI2070536T1 (sl) 2012-03-30
JP5132569B2 (ja) 2013-01-30
CA2664915A1 (en) 2008-04-17
ATE538789T1 (de) 2012-01-15
NZ575714A (en) 2011-05-27
JPWO2008044562A1 (ja) 2010-02-12
US8173157B2 (en) 2012-05-08
CN101522195A (zh) 2009-09-02
KR20090069317A (ko) 2009-06-30
MX2009003533A (es) 2009-07-17
AU2007305626A1 (en) 2008-04-17
PT2070536E (pt) 2012-03-06
CY1112617T1 (el) 2016-02-10
KR101409258B1 (ko) 2014-06-18
PL2070536T3 (pl) 2012-06-29
ES2376130T3 (es) 2012-03-09
US20100098750A1 (en) 2010-04-22
AU2007305626B2 (en) 2013-01-10
EP2070536A1 (en) 2009-06-17
WO2008044562A1 (fr) 2008-04-17

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