CY1112617T1 - Φαρμακευτικη συνθεση που περιεχει παραγωγο φαινυλαμιδινης και μεθοδος χρησης της φαρμακευτικης συνθεσης σε συνδυασμο με αντιμυκητιακο μεσο - Google Patents

Φαρμακευτικη συνθεση που περιεχει παραγωγο φαινυλαμιδινης και μεθοδος χρησης της φαρμακευτικης συνθεσης σε συνδυασμο με αντιμυκητιακο μεσο

Info

Publication number
CY1112617T1
CY1112617T1 CY20121100053T CY121100053T CY1112617T1 CY 1112617 T1 CY1112617 T1 CY 1112617T1 CY 20121100053 T CY20121100053 T CY 20121100053T CY 121100053 T CY121100053 T CY 121100053T CY 1112617 T1 CY1112617 T1 CY 1112617T1
Authority
CY
Cyprus
Prior art keywords
pharmaceutical composition
phenylamidine
antifungal agents
producer
agents
Prior art date
Application number
CY20121100053T
Other languages
English (en)
Inventor
Hiroshi Nishikawa
Original Assignee
Toyama Chemical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co., Ltd. filed Critical Toyama Chemical Co., Ltd.
Publication of CY1112617T1 publication Critical patent/CY1112617T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4465Non condensed piperidines, e.g. piperocaine only substituted in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4453Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Φαρμακευτική σύνθεση που περιέχει ένα παράγωγο φαινυλαμιδίνης ή ένα άλας αυτού, που αντιπροσωπεύεται από έναν γενικό τύπο,
CY20121100053T 2006-10-06 2012-01-17 Φαρμακευτικη συνθεση που περιεχει παραγωγο φαινυλαμιδινης και μεθοδος χρησης της φαρμακευτικης συνθεσης σε συνδυασμο με αντιμυκητιακο μεσο CY1112617T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006274709 2006-10-06
EP07829080A EP2070536B1 (en) 2006-10-06 2007-10-03 Pharmaceutical composition comprising phenylamidine derivative and method of using the pharmaceutical composition in combination with antifungal agent

Publications (1)

Publication Number Publication Date
CY1112617T1 true CY1112617T1 (el) 2016-02-10

Family

ID=39282771

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20121100053T CY1112617T1 (el) 2006-10-06 2012-01-17 Φαρμακευτικη συνθεση που περιεχει παραγωγο φαινυλαμιδινης και μεθοδος χρησης της φαρμακευτικης συνθεσης σε συνδυασμο με αντιμυκητιακο μεσο

Country Status (21)

Country Link
US (1) US8173157B2 (el)
EP (1) EP2070536B1 (el)
JP (1) JP5132569B2 (el)
KR (1) KR101409258B1 (el)
CN (1) CN101522195B (el)
AT (1) ATE538789T1 (el)
AU (1) AU2007305626B2 (el)
BR (1) BRPI0719157A2 (el)
CA (1) CA2664915C (el)
CY (1) CY1112617T1 (el)
DK (1) DK2070536T3 (el)
ES (1) ES2376130T3 (el)
MX (1) MX2009003533A (el)
NO (1) NO20091101L (el)
NZ (1) NZ575714A (el)
PL (1) PL2070536T3 (el)
PT (1) PT2070536E (el)
RU (1) RU2429843C2 (el)
SI (1) SI2070536T1 (el)
WO (1) WO2008044562A1 (el)
ZA (1) ZA200902053B (el)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI385169B (zh) 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd 經雜環取代之吡啶衍生物及含有彼之抗真菌劑
TW200841879A (en) 2007-04-27 2008-11-01 Eisai R&D Man Co Ltd Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same
TWI395735B (zh) * 2007-07-04 2013-05-11 Toyama Chemical Co Ltd 4-{3-〔4-(3-{4-〔胺基(丁氧基羰基亞胺基)甲基〕苯氧基}丙基)-1-哌啶基〕丙氧基}-n’-(丁氧基羰基)苄脒之新穎結晶
JPWO2012060448A1 (ja) 2010-11-05 2014-05-12 エーザイ・アール・アンド・ディー・マネジメント株式会社 抗真菌剤としての併用医薬組成物
RU2642934C2 (ru) 2012-04-20 2018-01-29 Эйсай Ар Энд Ди Менеджмент Ко., Лтд. Капсульный состав
JP7128181B2 (ja) 2016-10-31 2022-08-30 バイオクリスト ファーマスーティカルズ,インコーポレイテッド カリクレイン阻害剤のプロドラッグ

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4782059A (en) * 1986-09-29 1988-11-01 Merck & Co., Inc. Method of controlling mycotic infections and compositions therefor
JPH03288051A (ja) 1990-03-30 1991-12-18 Mazda Motor Corp カムシャフトおよびその製造方法
GB9509631D0 (en) * 1995-05-12 1995-07-05 Sandoz Ltd Antifungal combination
KR100380871B1 (ko) 1996-09-12 2003-04-18 머크 앤드 캄파니 인코포레이티드 항진균성 약제학적 조성물
AUPQ066399A0 (en) * 1999-05-31 1999-06-24 Fujisawa Pharmaceutical Co., Ltd. Antifungal combination use
EP1481966B1 (en) * 2002-03-06 2011-07-20 Toyama Chemical Co., Ltd. Novel arylamidine derivative or salt thereof
JP2007504460A (ja) 2003-09-05 2007-03-01 メルク エンド カムパニー インコーポレーテッド 固定相及び該固定相を用いた精製プロセス
JP4937506B2 (ja) * 2003-09-05 2012-05-23 富山化学工業株式会社 新規なアリールアミジン誘導体またはその塩
PT1767526E (pt) * 2004-06-30 2012-12-10 Toyama Chemical Co Ltd Derivado de arilamidina, os seus sais e um antifúngico que os contenha
CN1596897A (zh) 2004-07-26 2005-03-23 范敏华 一种伊曲康唑注射剂及其制备方法
WO2006011499A1 (ja) * 2004-07-28 2006-02-02 Toyama Chemical Co., Ltd. 新規なアリールアミジン誘導体およびその塩ならびにそれらを含有する抗真菌剤
ES2368078T3 (es) 2005-04-07 2011-11-14 Toyama Chemical Co., Ltd. Composición farmacéutica y método que usa un agente antifúngico en combinación.
JP5314284B2 (ja) 2005-11-09 2013-10-16 富山化学工業株式会社 4−(3−(4−(3−(4−シアノフェノキシ)プロピル)−1−ピペリジニル)プロポキシ)ベンゾニトリルの製造法およびその中間体
ES2349146T3 (es) * 2005-12-29 2010-12-28 Toyama Chemical Co., Ltd. Nuevo derivado de arilamida, su sal y un agente antifúngico que los comprende.

Also Published As

Publication number Publication date
ATE538789T1 (de) 2012-01-15
KR101409258B1 (ko) 2014-06-18
AU2007305626B2 (en) 2013-01-10
NO20091101L (no) 2009-04-27
CA2664915A1 (en) 2008-04-17
EP2070536B1 (en) 2011-12-28
ZA200902053B (en) 2010-07-28
US8173157B2 (en) 2012-05-08
KR20090069317A (ko) 2009-06-30
ES2376130T3 (es) 2012-03-09
RU2009117207A (ru) 2010-11-20
EP2070536A4 (en) 2010-02-10
WO2008044562A1 (fr) 2008-04-17
CN101522195A (zh) 2009-09-02
JPWO2008044562A1 (ja) 2010-02-12
AU2007305626A1 (en) 2008-04-17
CN101522195B (zh) 2012-01-18
NZ575714A (en) 2011-05-27
CA2664915C (en) 2014-01-07
MX2009003533A (es) 2009-07-17
EP2070536A1 (en) 2009-06-17
PT2070536E (pt) 2012-03-06
JP5132569B2 (ja) 2013-01-30
RU2429843C2 (ru) 2011-09-27
DK2070536T3 (da) 2012-04-10
US20100098750A1 (en) 2010-04-22
PL2070536T3 (pl) 2012-06-29
SI2070536T1 (sl) 2012-03-30
BRPI0719157A2 (pt) 2014-02-04

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