PL2070536T3 - Kompozycja farmaceutyczna zawierająca pochodną fenyloamidyny oraz sposób stosowania kompozycji farmaceutycznej w kombinacji ze środkiem przeciwgrzybiczym - Google Patents
Kompozycja farmaceutyczna zawierająca pochodną fenyloamidyny oraz sposób stosowania kompozycji farmaceutycznej w kombinacji ze środkiem przeciwgrzybiczymInfo
- Publication number
- PL2070536T3 PL2070536T3 PL07829080T PL07829080T PL2070536T3 PL 2070536 T3 PL2070536 T3 PL 2070536T3 PL 07829080 T PL07829080 T PL 07829080T PL 07829080 T PL07829080 T PL 07829080T PL 2070536 T3 PL2070536 T3 PL 2070536T3
- Authority
- PL
- Poland
- Prior art keywords
- pharmaceutical composition
- antifungal agents
- combination
- phenylamidine derivative
- agents
- Prior art date
Links
- 229940121375 antifungal agent Drugs 0.000 title abstract 5
- 239000003429 antifungal agent Substances 0.000 title abstract 5
- PXXJHWLDUBFPOL-UHFFFAOYSA-N benzamidine Chemical class NC(=N)C1=CC=CC=C1 PXXJHWLDUBFPOL-UHFFFAOYSA-N 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- WAVYAFBQOXCGSZ-UHFFFAOYSA-N 2-fluoropyrimidine Chemical compound FC1=NC=CC=N1 WAVYAFBQOXCGSZ-UHFFFAOYSA-N 0.000 abstract 1
- 206010017533 Fungal infection Diseases 0.000 abstract 1
- 208000031888 Mycoses Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 244000053095 fungal pathogen Species 0.000 abstract 1
- 150000004291 polyenes Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4465—Non condensed piperidines, e.g. piperocaine only substituted in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006274709 | 2006-10-06 | ||
| EP07829080A EP2070536B1 (en) | 2006-10-06 | 2007-10-03 | Pharmaceutical composition comprising phenylamidine derivative and method of using the pharmaceutical composition in combination with antifungal agent |
| PCT/JP2007/069341 WO2008044562A1 (en) | 2006-10-06 | 2007-10-03 | Pharmaceutical composition comprising phenylamidine derivative and method of using the pharmaceutical composition in combination with antifungal agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2070536T3 true PL2070536T3 (pl) | 2012-06-29 |
Family
ID=39282771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07829080T PL2070536T3 (pl) | 2006-10-06 | 2007-10-03 | Kompozycja farmaceutyczna zawierająca pochodną fenyloamidyny oraz sposób stosowania kompozycji farmaceutycznej w kombinacji ze środkiem przeciwgrzybiczym |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8173157B2 (pl) |
| EP (1) | EP2070536B1 (pl) |
| JP (1) | JP5132569B2 (pl) |
| KR (1) | KR101409258B1 (pl) |
| CN (1) | CN101522195B (pl) |
| AT (1) | ATE538789T1 (pl) |
| AU (1) | AU2007305626B2 (pl) |
| BR (1) | BRPI0719157A2 (pl) |
| CA (1) | CA2664915C (pl) |
| CY (1) | CY1112617T1 (pl) |
| DK (1) | DK2070536T3 (pl) |
| ES (1) | ES2376130T3 (pl) |
| MX (1) | MX2009003533A (pl) |
| NO (1) | NO20091101L (pl) |
| NZ (1) | NZ575714A (pl) |
| PL (1) | PL2070536T3 (pl) |
| PT (1) | PT2070536E (pl) |
| RU (1) | RU2429843C2 (pl) |
| SI (1) | SI2070536T1 (pl) |
| WO (1) | WO2008044562A1 (pl) |
| ZA (1) | ZA200902053B (pl) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI385169B (zh) | 2005-10-31 | 2013-02-11 | Eisai R&D Man Co Ltd | 經雜環取代之吡啶衍生物及含有彼之抗真菌劑 |
| TW200841879A (en) | 2007-04-27 | 2008-11-01 | Eisai R&D Man Co Ltd | Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same |
| TWI395735B (zh) * | 2007-07-04 | 2013-05-11 | Toyama Chemical Co Ltd | ４－｛３－〔４－（３－｛４－〔胺基（丁氧基羰基亞胺基）甲基〕苯氧基｝丙基）－１－哌啶基〕丙氧基｝－ｎ’－（丁氧基羰基）苄脒之新穎結晶 |
| WO2012060448A1 (ja) | 2010-11-05 | 2012-05-10 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 抗真菌剤としての併用医薬組成物 |
| AU2013250251B2 (en) | 2012-04-20 | 2017-05-11 | Eisai R&D Management Co., Ltd. | Encapsulated formulation |
| WO2018081513A1 (en) | 2016-10-31 | 2018-05-03 | Biocryst Pharmaceuticals, Inc. | Prodrugs of kallikrein inhibitors |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4782059A (en) * | 1986-09-29 | 1988-11-01 | Merck & Co., Inc. | Method of controlling mycotic infections and compositions therefor |
| JPH03288051A (ja) | 1990-03-30 | 1991-12-18 | Mazda Motor Corp | カムシャフトおよびその製造方法 |
| GB9509631D0 (en) * | 1995-05-12 | 1995-07-05 | Sandoz Ltd | Antifungal combination |
| EP0925070B1 (en) * | 1996-09-12 | 2003-09-03 | Merck & Co., Inc. | Antifungal combination therapy |
| AUPQ066399A0 (en) | 1999-05-31 | 1999-06-24 | Fujisawa Pharmaceutical Co., Ltd. | Antifungal combination use |
| FR2829362B1 (fr) * | 2001-09-10 | 2003-11-07 | Aventis Cropscience Sa | Composition fongicide a base de derives d'arylamidine et de composes fongicides connus |
| US7291617B2 (en) | 2002-03-06 | 2007-11-06 | Toyama Chemical Co., Ltd. | Arylamidine derivative or salt thereof |
| US20070010655A1 (en) * | 2003-09-05 | 2007-01-11 | Antia Firoz D | Stationary phases and a purification process using the stationary phases |
| JP4937506B2 (ja) | 2003-09-05 | 2012-05-23 | 富山化学工業株式会社 | 新規なアリールアミジン誘導体またはその塩 |
| WO2006003881A1 (ja) | 2004-06-30 | 2006-01-12 | Toyama Chemical Co., Ltd. | 新規なアリールアミジン誘導体およびその塩ならびにそれらを含有する抗真菌剤 |
| CN1596897A (zh) * | 2004-07-26 | 2005-03-23 | 范敏华 | 一种伊曲康唑注射剂及其制备方法 |
| WO2006011499A1 (ja) | 2004-07-28 | 2006-02-02 | Toyama Chemical Co., Ltd. | 新規なアリールアミジン誘導体およびその塩ならびにそれらを含有する抗真菌剤 |
| NZ561675A (en) | 2005-04-07 | 2010-07-30 | Toyama Chemical Co Ltd | Pharmaceutical composition and method using antifungal agent in combination |
| JP5314284B2 (ja) | 2005-11-09 | 2013-10-16 | 富山化学工業株式会社 | ４−（３−（４−（３−（４−シアノフェノキシ）プロピル）−１−ピペリジニル）プロポキシ）ベンゾニトリルの製造法およびその中間体 |
| ZA200805604B (en) * | 2005-12-29 | 2009-12-30 | Toyama Chemical Co Ltd | Novel arylamidine derivative, salt thereof and antifungal agent containing those |
-
2007
- 2007-10-03 PT PT07829080T patent/PT2070536E/pt unknown
- 2007-10-03 BR BRPI0719157-0A patent/BRPI0719157A2/pt not_active IP Right Cessation
- 2007-10-03 CA CA2664915A patent/CA2664915C/en not_active Expired - Fee Related
- 2007-10-03 EP EP07829080A patent/EP2070536B1/en not_active Not-in-force
- 2007-10-03 ZA ZA200902053A patent/ZA200902053B/xx unknown
- 2007-10-03 US US12/443,750 patent/US8173157B2/en not_active Expired - Fee Related
- 2007-10-03 WO PCT/JP2007/069341 patent/WO2008044562A1/ja not_active Ceased
- 2007-10-03 AU AU2007305626A patent/AU2007305626B2/en not_active Ceased
- 2007-10-03 MX MX2009003533A patent/MX2009003533A/es active IP Right Grant
- 2007-10-03 JP JP2008538673A patent/JP5132569B2/ja not_active Expired - Fee Related
- 2007-10-03 AT AT07829080T patent/ATE538789T1/de active
- 2007-10-03 KR KR1020097008232A patent/KR101409258B1/ko not_active Expired - Fee Related
- 2007-10-03 RU RU2009117207/15A patent/RU2429843C2/ru not_active IP Right Cessation
- 2007-10-03 DK DK07829080.6T patent/DK2070536T3/da active
- 2007-10-03 CN CN2007800371777A patent/CN101522195B/zh not_active Expired - Fee Related
- 2007-10-03 ES ES07829080T patent/ES2376130T3/es active Active
- 2007-10-03 SI SI200730827T patent/SI2070536T1/sl unknown
- 2007-10-03 NZ NZ575714A patent/NZ575714A/en not_active IP Right Cessation
- 2007-10-03 PL PL07829080T patent/PL2070536T3/pl unknown
-
2009
- 2009-03-13 NO NO20091101A patent/NO20091101L/no not_active Application Discontinuation
-
2012
- 2012-01-17 CY CY20121100053T patent/CY1112617T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2070536A4 (en) | 2010-02-10 |
| AU2007305626B2 (en) | 2013-01-10 |
| CN101522195A (zh) | 2009-09-02 |
| ES2376130T3 (es) | 2012-03-09 |
| SI2070536T1 (sl) | 2012-03-30 |
| KR20090069317A (ko) | 2009-06-30 |
| EP2070536A1 (en) | 2009-06-17 |
| RU2429843C2 (ru) | 2011-09-27 |
| BRPI0719157A2 (pt) | 2014-02-04 |
| ZA200902053B (en) | 2010-07-28 |
| JPWO2008044562A1 (ja) | 2010-02-12 |
| WO2008044562A1 (en) | 2008-04-17 |
| KR101409258B1 (ko) | 2014-06-18 |
| NO20091101L (no) | 2009-04-27 |
| NZ575714A (en) | 2011-05-27 |
| CN101522195B (zh) | 2012-01-18 |
| US8173157B2 (en) | 2012-05-08 |
| RU2009117207A (ru) | 2010-11-20 |
| ATE538789T1 (de) | 2012-01-15 |
| CY1112617T1 (el) | 2016-02-10 |
| PT2070536E (pt) | 2012-03-06 |
| MX2009003533A (es) | 2009-07-17 |
| CA2664915C (en) | 2014-01-07 |
| EP2070536B1 (en) | 2011-12-28 |
| AU2007305626A1 (en) | 2008-04-17 |
| US20100098750A1 (en) | 2010-04-22 |
| DK2070536T3 (da) | 2012-04-10 |
| JP5132569B2 (ja) | 2013-01-30 |
| CA2664915A1 (en) | 2008-04-17 |
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