DK2070536T3 - Farmaceutisk sammensætning med et phenylamidin-derivat og fremgangsmåde til anvendelse af den farmaceutiske sammensætning i kombination med et antifungalt middel - Google Patents

Farmaceutisk sammensætning med et phenylamidin-derivat og fremgangsmåde til anvendelse af den farmaceutiske sammensætning i kombination med et antifungalt middel

Info

Publication number
DK2070536T3
DK2070536T3 DK07829080.6T DK07829080T DK2070536T3 DK 2070536 T3 DK2070536 T3 DK 2070536T3 DK 07829080 T DK07829080 T DK 07829080T DK 2070536 T3 DK2070536 T3 DK 2070536T3
Authority
DK
Denmark
Prior art keywords
pharmaceutical composition
antifungal agents
combination
phenylamidine derivative
agents
Prior art date
Application number
DK07829080.6T
Other languages
English (en)
Inventor
Hiroshi Nishikawa
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Application granted granted Critical
Publication of DK2070536T3 publication Critical patent/DK2070536T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4465—Non condensed piperidines, e.g. piperocaine only substituted in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
DK07829080.6T 2006-10-06 2007-10-03 Farmaceutisk sammensætning med et phenylamidin-derivat og fremgangsmåde til anvendelse af den farmaceutiske sammensætning i kombination med et antifungalt middel DK2070536T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006274709 2006-10-06
PCT/JP2007/069341 WO2008044562A1 (fr) 2006-10-06 2007-10-03 Composition pharmaceutique contenant un dérivé de phénylamidine et procédé d'utilisation de la composition pharmaceutique combinée à un agent antifongique

Publications (1)

Publication Number Publication Date
DK2070536T3 true DK2070536T3 (da) 2012-04-10

Family

ID=39282771

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07829080.6T DK2070536T3 (da) 2006-10-06 2007-10-03 Farmaceutisk sammensætning med et phenylamidin-derivat og fremgangsmåde til anvendelse af den farmaceutiske sammensætning i kombination med et antifungalt middel

Country Status (21)

Country Link
US (1) US8173157B2 (da)
EP (1) EP2070536B1 (da)
JP (1) JP5132569B2 (da)
KR (1) KR101409258B1 (da)
CN (1) CN101522195B (da)
AT (1) ATE538789T1 (da)
AU (1) AU2007305626B2 (da)
BR (1) BRPI0719157A2 (da)
CA (1) CA2664915C (da)
CY (1) CY1112617T1 (da)
DK (1) DK2070536T3 (da)
ES (1) ES2376130T3 (da)
MX (1) MX2009003533A (da)
NO (1) NO20091101L (da)
NZ (1) NZ575714A (da)
PL (1) PL2070536T3 (da)
PT (1) PT2070536E (da)
RU (1) RU2429843C2 (da)
SI (1) SI2070536T1 (da)
WO (1) WO2008044562A1 (da)
ZA (1) ZA200902053B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI385169B (zh) 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd 經雜環取代之吡啶衍生物及含有彼之抗真菌劑
TW200841879A (en) 2007-04-27 2008-11-01 Eisai R&D Man Co Ltd Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same
TWI395735B (zh) * 2007-07-04 2013-05-11 Toyama Chemical Co Ltd ４－｛３－〔４－（３－｛４－〔胺基（丁氧基羰基亞胺基）甲基〕苯氧基｝丙基）－１－哌啶基〕丙氧基｝－ｎ’－（丁氧基羰基）苄脒之新穎結晶
JPWO2012060448A1 (ja) 2010-11-05 2014-05-12 エーザイ・アール・アンド・ディー・マネジメント株式会社 抗真菌剤としての併用医薬組成物
RU2642934C2 (ru) 2012-04-20 2018-01-29 Эйсай Ар Энд Ди Менеджмент Ко., Лтд. Капсульный состав
JP7128181B2 (ja) 2016-10-31 2022-08-30 バイオクリスト ファーマスーティカルズ，インコーポレイテッド カリクレイン阻害剤のプロドラッグ

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4782059A (en) * 1986-09-29 1988-11-01 Merck & Co., Inc. Method of controlling mycotic infections and compositions therefor
JPH03288051A (ja) 1990-03-30 1991-12-18 Mazda Motor Corp カムシャフトおよびその製造方法
GB9509631D0 (en) * 1995-05-12 1995-07-05 Sandoz Ltd Antifungal combination
KR100380871B1 (ko) 1996-09-12 2003-04-18 머크 앤드 캄파니 인코포레이티드 항진균성 약제학적 조성물
AUPQ066399A0 (en) * 1999-05-31 1999-06-24 Fujisawa Pharmaceutical Co., Ltd. Antifungal combination use
EP1481966B1 (en) * 2002-03-06 2011-07-20 Toyama Chemical Co., Ltd. Novel arylamidine derivative or salt thereof
JP2007504460A (ja) 2003-09-05 2007-03-01 メルク　エンド　カムパニー　インコーポレーテッド 固定相及び該固定相を用いた精製プロセス
JP4937506B2 (ja) * 2003-09-05 2012-05-23 富山化学工業株式会社 新規なアリールアミジン誘導体またはその塩
PT1767526E (pt) * 2004-06-30 2012-12-10 Toyama Chemical Co Ltd Derivado de arilamidina, os seus sais e um antifúngico que os contenha
CN1596897A (zh) 2004-07-26 2005-03-23 范敏华 一种伊曲康唑注射剂及其制备方法
WO2006011499A1 (ja) * 2004-07-28 2006-02-02 Toyama Chemical Co., Ltd. 新規なアリールアミジン誘導体およびその塩ならびにそれらを含有する抗真菌剤
ES2368078T3 (es) 2005-04-07 2011-11-14 Toyama Chemical Co., Ltd. Composición farmacéutica y método que usa un agente antifúngico en combinación.
JP5314284B2 (ja) 2005-11-09 2013-10-16 富山化学工業株式会社 ４−（３−（４−（３−（４−シアノフェノキシ）プロピル）−１−ピペリジニル）プロポキシ）ベンゾニトリルの製造法およびその中間体
ES2349146T3 (es) * 2005-12-29 2010-12-28 Toyama Chemical Co., Ltd. Nuevo derivado de arilamida, su sal y un agente antifúngico que los comprende.

Also Published As

Publication number Publication date
ATE538789T1 (de) 2012-01-15
KR101409258B1 (ko) 2014-06-18
AU2007305626B2 (en) 2013-01-10
NO20091101L (no) 2009-04-27
CA2664915A1 (en) 2008-04-17
EP2070536B1 (en) 2011-12-28
ZA200902053B (en) 2010-07-28
US8173157B2 (en) 2012-05-08
KR20090069317A (ko) 2009-06-30
ES2376130T3 (es) 2012-03-09
RU2009117207A (ru) 2010-11-20
EP2070536A4 (en) 2010-02-10
WO2008044562A1 (fr) 2008-04-17
CY1112617T1 (el) 2016-02-10
CN101522195A (zh) 2009-09-02
JPWO2008044562A1 (ja) 2010-02-12
AU2007305626A1 (en) 2008-04-17
CN101522195B (zh) 2012-01-18
NZ575714A (en) 2011-05-27
CA2664915C (en) 2014-01-07
MX2009003533A (es) 2009-07-17
EP2070536A1 (en) 2009-06-17
PT2070536E (pt) 2012-03-06
JP5132569B2 (ja) 2013-01-30
RU2429843C2 (ru) 2011-09-27
US20100098750A1 (en) 2010-04-22
PL2070536T3 (pl) 2012-06-29
SI2070536T1 (sl) 2012-03-30
BRPI0719157A2 (pt) 2014-02-04

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