NO20084856L - Aktivator for peroksisom proliferator aktivert reseptor - Google Patents

Aktivator for peroksisom proliferator aktivert reseptor

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Publication number
NO20084856L
NO20084856L NO20084856A NO20084856A NO20084856L NO 20084856 L NO20084856 L NO 20084856L NO 20084856 A NO20084856 A NO 20084856A NO 20084856 A NO20084856 A NO 20084856A NO 20084856 L NO20084856 L NO 20084856L
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Norway
Prior art keywords
activator
halogen
activated receptor
alkyl
peroxisome proliferator
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NO20084856A
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English (en)
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NO341476B1 (no
Inventor
Shogo Sakuma
Nobutaka Mochiduki
Rie Takahashi
Tomio Yamakawa
Seiichiro Masui
Masatoshi Ushioda
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Nippon Chemiphar Co
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Publication of NO20084856L publication Critical patent/NO20084856L/no
Publication of NO341476B1 publication Critical patent/NO341476B1/no

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    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom

Abstract

En forbindelse representert ved følgende generelle formel (II) eller et salt derav anvendes som en aktivator av PPAR5. hvori Ga er CH2 eller lignende; Aa er tiazol, oksazol eller tiofen, som kan ha en substituent slik som C1-8 alkyl, Ci.g alkoksy, halogen, d-s alkyl substituert med halogen eller lignende; Ba er en C i-s alkyl en eller C2-8 alkenylenkjede; og hver av Rla og R2a er uavhengig hydrogen, Ci_8 alkyl, C\.g alkoksy, halogen, Ci-s substituert med halogen eller lignende.
NO20084856A 2006-04-18 2008-11-18 Aktiveringsmiddel for proksisomproliferatoraktivert reseptor  NO341476B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006114561 2006-04-18
PCT/JP2007/058899 WO2007119887A1 (ja) 2006-04-18 2007-04-18 ペルオキシソーム増殖剤活性化受容体δの活性化剤

Publications (2)

Publication Number Publication Date
NO20084856L true NO20084856L (no) 2008-12-29
NO341476B1 NO341476B1 (no) 2017-11-27

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NO20084856A NO341476B1 (no) 2006-04-18 2008-11-18 Aktiveringsmiddel for proksisomproliferatoraktivert reseptor 

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US (2) US8404726B2 (no)
EP (1) EP2014652B1 (no)
JP (3) JP5290749B2 (no)
KR (1) KR101507173B1 (no)
CN (2) CN102643248A (no)
AU (1) AU2007239283B2 (no)
BR (1) BRPI0710266B8 (no)
CA (1) CA2649735C (no)
CY (1) CY1115637T1 (no)
DK (1) DK2014652T3 (no)
ES (1) ES2522291T3 (no)
HK (1) HK1135377A1 (no)
IL (1) IL194847A (no)
MX (1) MX2008013292A (no)
MY (1) MY154836A (no)
NO (1) NO341476B1 (no)
NZ (1) NZ572268A (no)
PL (1) PL2014652T3 (no)
PT (1) PT2014652E (no)
RU (1) RU2435764C2 (no)
SI (1) SI2014652T1 (no)
WO (1) WO2007119887A1 (no)
ZA (1) ZA200809148B (no)

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CN110183422B (zh) 2013-06-21 2023-07-14 卡尔约药物治疗公司 核转运调节剂及其用途
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