BRPI0606845A2 - derivados de (1,5-difenil-1h-pirazol-3-il)oxadiazol, o respectivo preparo e a respectiva aplicação em terapêutica - Google Patents

derivados de (1,5-difenil-1h-pirazol-3-il)oxadiazol, o respectivo preparo e a respectiva aplicação em terapêutica

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Publication number
BRPI0606845A2
BRPI0606845A2 BRPI0606845-6A BRPI0606845A BRPI0606845A2 BR PI0606845 A2 BRPI0606845 A2 BR PI0606845A2 BR PI0606845 A BRPI0606845 A BR PI0606845A BR PI0606845 A2 BRPI0606845 A2 BR PI0606845A2
Authority
BR
Brazil
Prior art keywords
preparation
therapeutic application
pyrazol
diphenyl
oxadiazole derivatives
Prior art date
Application number
BRPI0606845-6A
Other languages
English (en)
Inventor
Francis Barth
Patrick Gueule
Murielle Rinaldi-Carmona
Didier Van Broeck
Christian Congy
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35079215&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0606845(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of BRPI0606845A2 publication Critical patent/BRPI0606845A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
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Abstract

DERIVADOS DE (1,5-DIFENIL-1H-PIRAZOL-3-IL)OXADIAZOL, O RESPECTIVO PREPARO E A RESPECTIVA APLICAçãO EM TERAPêUTICA. A presente invenção refere-se a compostos correspondentes à fórmula (I), na qual: - R~ 1~ representa um radical heterocíclico escolhido dentre fórmula (II); - R~ 2~ representa uma (C~ 1~-C~ 5~)alquila ou um ciano; - R~ 3~ representa uma fenila não substituida ou substituida; - R~ 4~ representa uma fenila não substituida ou substituida; assim como seus hidratos ou seus solvatos.
BRPI0606845-6A 2005-02-21 2006-02-17 derivados de (1,5-difenil-1h-pirazol-3-il)oxadiazol, o respectivo preparo e a respectiva aplicação em terapêutica BRPI0606845A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0501860A FR2882365B1 (fr) 2005-02-21 2005-02-21 Derives de 2-(1,5-diphenyl-1h-pyrazol-3-yl)-1,3,4-oxadiazole leur preparation et leur application en therapeutique
PCT/FR2006/000368 WO2006087480A1 (fr) 2005-02-21 2006-02-17 DERIVES DE (l,5-DIPHENYL-lH-PYRAZOL-3-YL)OXADIAZOLE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE

Publications (1)

Publication Number Publication Date
BRPI0606845A2 true BRPI0606845A2 (pt) 2009-07-21

Family

ID=35079215

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0606845-6A BRPI0606845A2 (pt) 2005-02-21 2006-02-17 derivados de (1,5-difenil-1h-pirazol-3-il)oxadiazol, o respectivo preparo e a respectiva aplicação em terapêutica

Country Status (25)

Country Link
US (1) US7632852B2 (pt)
EP (1) EP1853595A1 (pt)
JP (1) JP4812778B2 (pt)
KR (1) KR20070107053A (pt)
CN (1) CN101119990A (pt)
AR (1) AR055560A1 (pt)
AU (1) AU2006215443A1 (pt)
BR (1) BRPI0606845A2 (pt)
CA (1) CA2597359A1 (pt)
DO (1) DOP2006000045A (pt)
EA (1) EA200701779A1 (pt)
FR (1) FR2882365B1 (pt)
GT (1) GT200600082A (pt)
IL (1) IL185163A0 (pt)
MA (1) MA29261B1 (pt)
MX (1) MX2007009994A (pt)
NO (1) NO20074763L (pt)
NZ (1) NZ560790A (pt)
PA (1) PA8663901A1 (pt)
PE (1) PE20061038A1 (pt)
SV (1) SV2007002422A (pt)
TW (1) TW200640916A (pt)
UY (1) UY29388A1 (pt)
WO (1) WO2006087480A1 (pt)
ZA (1) ZA200706953B (pt)

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DE10361258A1 (de) * 2003-12-24 2005-07-28 Schwarz Pharma Ag Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson
BRPI0715160A2 (pt) 2006-08-08 2013-06-11 Sanofi Aventis imidazolidina-2,4-dionas substituÍdas por arilamimoaril-alquil-, processo para preparÁ-las, medicamentos compeendendo estes compostos, e seu uso
JP5269795B2 (ja) * 2006-09-29 2013-08-21 グリーン・クロス・コーポレイション カンナビノイドｃｂ１受容体アンタゴニストとしてのヘテロアリール−ピラゾール誘導体
US7875647B2 (en) 2006-09-29 2011-01-25 Green Cross Corporation Heteroaryl-pyrazole derivatives as cannabinoid CB1 receptor antagonists
US20080207704A1 (en) * 2007-02-27 2008-08-28 The Green Cross Corporation Heteroaryl-imidazole derivatives as cannabinoid cb1 receptor antagonists
US7705024B2 (en) 2007-04-12 2010-04-27 National Health Research Institutes Oxadiazole compounds
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
WO2009078498A1 (en) * 2007-12-17 2009-06-25 Green Cross Corporation Biarylpyrazole 4-carboxamides as cannabinoid cb1 receptor ligands
AR072707A1 (es) 2008-07-09 2010-09-15 Sanofi Aventis Compuestos heterociclicos, procesos para su preparacion, medicamentos que comprenden estos compuestos y el uso de los mismos
KR101318689B1 (ko) 2008-09-25 2013-10-16 주식회사 녹십자 칸나비노이드 ｃｂ1 수용체 길항제로서 황 함유 피라졸-헤테로사이클 유도체
WO2010068601A1 (en) 2008-12-08 2010-06-17 Sanofi-Aventis A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
RU2012111354A (ru) 2009-08-26 2013-10-10 Санофи Новые кристаллические гидраты фторгликозидов, содержащие их фармацевтические препараты и их использование
US8933024B2 (en) 2010-06-18 2015-01-13 Sanofi Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
EP2683704B1 (de) 2011-03-08 2014-12-17 Sanofi Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120055A1 (de) 2011-03-08 2012-09-13 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8901114B2 (en) 2011-03-08 2014-12-02 Sanofi Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
WO2012120056A1 (de) 2011-03-08 2012-09-13 Sanofi Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120054A1 (de) 2011-03-08 2012-09-13 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
CN109651350B (zh) * 2019-01-11 2022-05-24 贵州大学 一类杂环取代的1,3,4-噁(噻)二唑类化合物及其制备方法和用途
CN109942567B (zh) * 2019-04-30 2023-04-07 贵州大学 一种1,3,4-噁(噻)二唑基的咪唑类化合物及其制备方法和用途

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PE20061038A1 (es) 2006-11-24
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EA200701779A1 (ru) 2008-02-28
ZA200706953B (en) 2009-03-25
NO20074763L (no) 2007-11-16
CN101119990A (zh) 2008-02-06
AU2006215443A1 (en) 2006-08-24
NZ560790A (en) 2009-08-28
WO2006087480A1 (fr) 2006-08-24
CA2597359A1 (fr) 2006-08-24
DOP2006000045A (es) 2006-11-15
FR2882365B1 (fr) 2007-09-07
US7632852B2 (en) 2009-12-15
AR055560A1 (es) 2007-08-22
UY29388A1 (es) 2006-10-02
SV2007002422A (es) 2007-01-17
IL185163A0 (en) 2007-12-03
TW200640916A (en) 2006-12-01
JP2008530188A (ja) 2008-08-07
KR20070107053A (ko) 2007-11-06
FR2882365A1 (fr) 2006-08-25
PA8663901A1 (es) 2006-12-07
MX2007009994A (es) 2007-10-10
GT200600082A (es) 2006-10-19
EP1853595A1 (fr) 2007-11-14
US20080039510A1 (en) 2008-02-14

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