NO20084257L - Diketopiperazin og piperidin derivater som antivirale midler - Google Patents

Diketopiperazin og piperidin derivater som antivirale midler

Info

Publication number
NO20084257L
NO20084257L NO20084257A NO20084257A NO20084257L NO 20084257 L NO20084257 L NO 20084257L NO 20084257 A NO20084257 A NO 20084257A NO 20084257 A NO20084257 A NO 20084257A NO 20084257 L NO20084257 L NO 20084257L
Authority
NO
Norway
Prior art keywords
piperidine derivatives
diketopiperazine
antivirals
diketo
piperazine
Prior art date
Application number
NO20084257A
Other languages
English (en)
Other versions
NO341412B1 (no
Inventor
Tao Wang
John F Kadow
Zhongxing Zhang
Zhiwei Yin
Nicholas A Meanwell
Alicia Regueiro-Ren
Jacob Swidorski
Ying Han
David J Carini
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO20084257L publication Critical patent/NO20084257L/no
Publication of NO341412B1 publication Critical patent/NO341412B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Det beskrives forbindelser som har medikament- og biopåvirkende egenskaper, deres farmasøytiske blandinger og fremgangsmåte for deres anvendelse. Særlig beskrives diketo-piperazin- og -piperidin-derivater som har unik antiviral aktivitet. Nærmere bestemt beskriver oppfinnelsen forbindelser som er anvendelige for behandling av HIV og AIDS.
NO20084257A 2006-04-25 2008-10-10 Diketo-piperazin- og –piperidinderivater, farmasøytiske blandinger omfattende slike, slike blandinger omfattende ytterligere anti-HIV midler og slike blandinger for behandling av sykdom NO341412B1 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US79470006P 2006-04-25 2006-04-25
US79470306P 2006-04-25 2006-04-25
US11/733,283 US7807671B2 (en) 2006-04-25 2007-04-10 Diketo-piperazine and piperidine derivatives as antiviral agents
PCT/US2007/066700 WO2007127635A2 (en) 2006-04-25 2007-04-16 Diketo-piperazine and piperidine derivatives as antiviral agents

Publications (2)

Publication Number Publication Date
NO20084257L true NO20084257L (no) 2008-11-19
NO341412B1 NO341412B1 (no) 2017-10-30

Family

ID=38335673

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20084257A NO341412B1 (no) 2006-04-25 2008-10-10 Diketo-piperazin- og –piperidinderivater, farmasøytiske blandinger omfattende slike, slike blandinger omfattende ytterligere anti-HIV midler og slike blandinger for behandling av sykdom

Country Status (17)

Country Link
US (2) US7807671B2 (no)
EP (1) EP2010525B1 (no)
JP (1) JP5214590B2 (no)
KR (1) KR101450349B1 (no)
AR (1) AR060658A1 (no)
AU (1) AU2007242989B2 (no)
BR (1) BRPI0710919A2 (no)
CA (1) CA2650382C (no)
EA (1) EA014957B1 (no)
ES (1) ES2432758T3 (no)
IL (1) IL194540A (no)
MX (1) MX2008013265A (no)
NO (1) NO341412B1 (no)
NZ (1) NZ571995A (no)
PE (1) PE20080318A1 (no)
TW (1) TWI394754B (no)
WO (1) WO2007127635A2 (no)

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PE20080318A1 (es) 2008-04-10
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US7807676B2 (en) 2010-10-05
CA2650382C (en) 2014-05-27
KR20090005393A (ko) 2009-01-13
US20080139572A1 (en) 2008-06-12
BRPI0710919A2 (pt) 2012-06-26
IL194540A (en) 2015-03-31
US7807671B2 (en) 2010-10-05
JP5214590B2 (ja) 2013-06-19
EP2010525A2 (en) 2009-01-07
MX2008013265A (es) 2008-10-27
NZ571995A (en) 2011-11-25
AU2007242989A1 (en) 2007-11-08
TW200811174A (en) 2008-03-01
US20070249579A1 (en) 2007-10-25
IL194540A0 (en) 2009-08-03
AR060658A1 (es) 2008-07-02
JP2009535352A (ja) 2009-10-01
KR101450349B1 (ko) 2014-10-14
NO341412B1 (no) 2017-10-30
AU2007242989B2 (en) 2012-06-28
ES2432758T3 (es) 2013-12-05
EA014957B1 (ru) 2011-04-29
WO2007127635A3 (en) 2008-03-13
EA200802203A1 (ru) 2009-04-28
CA2650382A1 (en) 2007-11-08
WO2007127635A2 (en) 2007-11-08

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