US619455A
(en)
|
|
1899-02-14 |
|
Steaming vessel |
BE666904A
(no)
|
1964-07-14 |
|
|
|
GB1219606A
(en)
|
1968-07-15 |
1971-01-20 |
Rech S Et D Applic Scient Soge |
Quinuclidinol derivatives and preparation thereof
|
US4399216A
(en)
|
1980-02-25 |
1983-08-16 |
The Trustees Of Columbia University |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
US5179017A
(en)
|
1980-02-25 |
1993-01-12 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
US4634665A
(en)
|
1980-02-25 |
1987-01-06 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
US4475196A
(en)
|
1981-03-06 |
1984-10-02 |
Zor Clair G |
Instrument for locating faults in aircraft passenger reading light and attendant call control system
|
US4447233A
(en)
|
1981-04-10 |
1984-05-08 |
Parker-Hannifin Corporation |
Medication infusion pump
|
US4439196A
(en)
|
1982-03-18 |
1984-03-27 |
Merck & Co., Inc. |
Osmotic drug delivery system
|
US4522811A
(en)
|
1982-07-08 |
1985-06-11 |
Syntex (U.S.A.) Inc. |
Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
|
US4447224A
(en)
|
1982-09-20 |
1984-05-08 |
Infusaid Corporation |
Variable flow implantable infusion apparatus
|
US4487603A
(en)
|
1982-11-26 |
1984-12-11 |
Cordis Corporation |
Implantable microinfusion pump system
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
US4486194A
(en)
|
1983-06-08 |
1984-12-04 |
James Ferrara |
Therapeutic device for administering medicaments through the skin
|
EP0147716A3
(de)
|
1983-12-24 |
1987-10-28 |
ANT Nachrichtentechnik GmbH |
Verfahren und Anordnung zur verschlüsselbaren Übertragung einer Nachrichten-Binärzeichenfolge mit Authentizitätsprüfung
|
EP0154316B1
(en)
|
1984-03-06 |
1989-09-13 |
Takeda Chemical Industries, Ltd. |
Chemically modified lymphokine and production thereof
|
US4596556A
(en)
|
1985-03-25 |
1986-06-24 |
Bioject, Inc. |
Hypodermic injection apparatus
|
US5374548A
(en)
|
1986-05-02 |
1994-12-20 |
Genentech, Inc. |
Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor
|
MX9203291A
(es)
|
1985-06-26 |
1992-08-01 |
Liposome Co Inc |
Metodo para acoplamiento de liposomas.
|
JPS6235216A
(ja)
|
1985-08-09 |
1987-02-16 |
Noritoshi Nakabachi |
不均質物質層の層厚非破壊測定方法および装置
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
US4954617A
(en)
|
1986-07-07 |
1990-09-04 |
Trustees Of Dartmouth College |
Monoclonal antibodies to FC receptors for immunoglobulin G on human mononuclear phagocytes
|
US4881175A
(en)
|
1986-09-02 |
1989-11-14 |
Genex Corporation |
Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides
|
US5260203A
(en)
|
1986-09-02 |
1993-11-09 |
Enzon, Inc. |
Single polypeptide chain binding molecules
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
DE3883899T3
(de)
|
1987-03-18 |
1999-04-22 |
Sb2, Inc., Danville, Calif. |
Geänderte antikörper.
|
US5013653A
(en)
|
1987-03-20 |
1991-05-07 |
Creative Biomolecules, Inc. |
Product and process for introduction of a hinge region into a fusion protein to facilitate cleavage
|
DE3853515T3
(de)
|
1987-05-21 |
2005-08-25 |
Micromet Ag |
Multifunktionelle proteine mit vorbestimmter zielsetzung.
|
US5258498A
(en)
|
1987-05-21 |
1993-11-02 |
Creative Biomolecules, Inc. |
Polypeptide linkers for production of biosynthetic proteins
|
US5132405A
(en)
|
1987-05-21 |
1992-07-21 |
Creative Biomolecules, Inc. |
Biosynthetic antibody binding sites
|
US5091513A
(en)
|
1987-05-21 |
1992-02-25 |
Creative Biomolecules, Inc. |
Biosynthetic antibody binding sites
|
US4790824A
(en)
|
1987-06-19 |
1988-12-13 |
Bioject, Inc. |
Non-invasive hypodermic injection device
|
US4941880A
(en)
|
1987-06-19 |
1990-07-17 |
Bioject, Inc. |
Pre-filled ampule and non-invasive hypodermic injection device assembly
|
US5677425A
(en)
|
1987-09-04 |
1997-10-14 |
Celltech Therapeutics Limited |
Recombinant antibody
|
US5476996A
(en)
|
1988-06-14 |
1995-12-19 |
Lidak Pharmaceuticals |
Human immune system in non-human animal
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
CA2006596C
(en)
|
1988-12-22 |
2000-09-05 |
Rika Ishikawa |
Chemically-modified g-csf
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
US5108921A
(en)
|
1989-04-03 |
1992-04-28 |
Purdue Research Foundation |
Method for enhanced transmembrane transport of exogenous molecules
|
GB8916480D0
(en)
|
1989-07-19 |
1989-09-06 |
Glaxo Group Ltd |
Chemical process
|
GB8923590D0
(en)
|
1989-10-19 |
1989-12-06 |
Pfizer Ltd |
Antimuscarinic bronchodilators
|
US5064413A
(en)
|
1989-11-09 |
1991-11-12 |
Bioject, Inc. |
Needleless hypodermic injection device
|
US5312335A
(en)
|
1989-11-09 |
1994-05-17 |
Bioject Inc. |
Needleless hypodermic injection device
|
US6713610B1
(en)
|
1990-01-12 |
2004-03-30 |
Raju Kucherlapati |
Human antibodies derived from immunized xenomice
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
US6673986B1
(en)
|
1990-01-12 |
2004-01-06 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
EP0463151B1
(en)
|
1990-01-12 |
1996-06-12 |
Cell Genesys, Inc. |
Generation of xenogeneic antibodies
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
US6172197B1
(en)
|
1991-07-10 |
2001-01-09 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
US5877397A
(en)
|
1990-08-29 |
1999-03-02 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
US5789650A
(en)
|
1990-08-29 |
1998-08-04 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
DE69127627T2
(de)
|
1990-08-29 |
1998-02-19 |
Genpharm Int |
Produktion und Nützung nicht-menschliche transgentiere zur Produktion heterologe Antikörper
|
US6255458B1
(en)
|
1990-08-29 |
2001-07-03 |
Genpharm International |
High affinity human antibodies and human antibodies against digoxin
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
US6300129B1
(en)
|
1990-08-29 |
2001-10-09 |
Genpharm International |
Transgenic non-human animals for producing heterologous antibodies
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US5874299A
(en)
|
1990-08-29 |
1999-02-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
PT100441A
(pt)
|
1991-05-02 |
1993-09-30 |
Smithkline Beecham Corp |
Pirrolidinonas, seu processo de preparacao, composicoes farmaceuticas que as contem e uso
|
US5451700A
(en)
|
1991-06-11 |
1995-09-19 |
Ciba-Geigy Corporation |
Amidino compounds, their manufacture and methods of treatment
|
JPH0525045A
(ja)
|
1991-07-18 |
1993-02-02 |
Tanabe Seiyaku Co Ltd |
経皮吸収製剤
|
ATE463573T1
(de)
|
1991-12-02 |
2010-04-15 |
Medimmune Ltd |
Herstellung von autoantikörpern auf phagenoberflächen ausgehend von antikörpersegmentbibliotheken
|
AU3328493A
(en)
|
1991-12-17 |
1993-07-19 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US5714350A
(en)
|
1992-03-09 |
1998-02-03 |
Protein Design Labs, Inc. |
Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region
|
WO1993018007A1
(en)
|
1992-03-13 |
1993-09-16 |
Tokyo Tanabe Company Limited |
Novel carbostyril derivative
|
WO1993019751A1
(en)
|
1992-04-02 |
1993-10-14 |
Smithkline Beecham Corporation |
Compounds useful for treating inflammatory diseases and inhibiting production of tumor necrosis factor
|
WO1993019750A1
(en)
|
1992-04-02 |
1993-10-14 |
Smithkline Beecham Corporation |
Compounds useful for treating allergic or inflammatory diseases
|
MX9301943A
(es)
|
1992-04-02 |
1994-08-31 |
Smithkline Beecham Corp |
Compuestos.
|
CA2118508A1
(en)
|
1992-04-24 |
1993-11-11 |
Elizabeth S. Ward |
Recombinant production of immunoglobulin-like domains in prokaryotic cells
|
US5383851A
(en)
|
1992-07-24 |
1995-01-24 |
Bioject Inc. |
Needleless hypodermic injection device
|
WO1994004680A1
(en)
|
1992-08-21 |
1994-03-03 |
Schering Corporation |
Human interleukin-13
|
GB9223377D0
(en)
|
1992-11-04 |
1992-12-23 |
Medarex Inc |
Humanized antibodies to fc receptors for immunoglobulin on human mononuclear phagocytes
|
GB9301000D0
(en)
|
1993-01-20 |
1993-03-10 |
Glaxo Group Ltd |
Chemical compounds
|
CA2161351C
(en)
|
1993-04-26 |
2010-12-21 |
Nils Lonberg |
Transgenic non-human animals capable of producing heterologous antibodies
|
AU691811B2
(en)
|
1993-06-16 |
1998-05-28 |
Celltech Therapeutics Limited |
Antibodies
|
US5625825A
(en)
|
1993-10-21 |
1997-04-29 |
Lsi Logic Corporation |
Random number generating apparatus for an interface unit of a carrier sense with multiple access and collision detect (CSMA/CD) ethernet data network
|
GB9414193D0
(en)
|
1994-07-14 |
1994-08-31 |
Glaxo Group Ltd |
Compounds
|
GB9414208D0
(en)
|
1994-07-14 |
1994-08-31 |
Glaxo Group Ltd |
Compounds
|
US6121022A
(en)
|
1995-04-14 |
2000-09-19 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
US5869046A
(en)
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
US6664227B1
(en)
|
1996-03-01 |
2003-12-16 |
Genetics Institute, Llc |
Treatment of fibrosis by antagonism of IL-13 and IL-13 receptor chains
|
GB9622386D0
(en)
|
1996-10-28 |
1997-01-08 |
Sandoz Ltd |
Organic compounds
|
TW528755B
(en)
|
1996-12-24 |
2003-04-21 |
Glaxo Group Ltd |
2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
|
US6277375B1
(en)
|
1997-03-03 |
2001-08-21 |
Board Of Regents, The University Of Texas System |
Immunoglobulin-like domains with increased half-lives
|
AU736549B2
(en)
|
1997-05-21 |
2001-08-02 |
Merck Patent Gesellschaft Mit Beschrankter Haftung |
Method for the production of non-immunogenic proteins
|
US6166037A
(en)
|
1997-08-28 |
2000-12-26 |
Merck & Co., Inc. |
Pyrrolidine and piperidine modulators of chemokine receptor activity
|
WO1999016766A1
(fr)
|
1997-10-01 |
1999-04-08 |
Kyowa Hakko Kogyo Co., Ltd. |
Derives de benzodioxole
|
GB9723566D0
(en)
|
1997-11-08 |
1998-01-07 |
Glaxo Group Ltd |
Chemical compounds
|
GB9723590D0
(en)
|
1997-11-08 |
1998-01-07 |
Glaxo Group Ltd |
Chemical compounds
|
GB9723589D0
(en)
|
1997-11-08 |
1998-01-07 |
Glaxo Group Ltd |
Chemical compounds
|
YU44900A
(sh)
|
1998-01-31 |
2003-01-31 |
Glaxo Group Limited |
Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
|
AR017457A1
(es)
|
1998-02-14 |
2001-09-05 |
Glaxo Group Ltd |
Compuestos derivados de 2-(purin-9-il)-tetrahidrofuran-3,4-diol, procesos para su preparacion, composiciones que los contienen y su uso en terapia para el tratamiento de enfermedades inflamatorias.
|
US6194551B1
(en)
|
1998-04-02 |
2001-02-27 |
Genentech, Inc. |
Polypeptide variants
|
DK2180007T4
(da)
|
1998-04-20 |
2017-11-27 |
Roche Glycart Ag |
Glycosyleringsteknik for antistoffer til forbedring af antistofafhængig cellecytotoxicitet
|
US6541669B1
(en)
|
1998-06-08 |
2003-04-01 |
Theravance, Inc. |
β2-adrenergic receptor agonists
|
GB9813535D0
(en)
|
1998-06-23 |
1998-08-19 |
Glaxo Group Ltd |
Chemical compounds
|
GB9813565D0
(en)
|
1998-06-23 |
1998-08-19 |
Glaxo Group Ltd |
Chemical compounds
|
HUP0103025A3
(en)
|
1998-06-23 |
2002-04-29 |
Glaxo Group Ltd |
A2a agonist 2-(purin-9-yl)tetrahydrofuran-3,4-diol derivatives, medicaments containing the same, process for producing them and the useful intermediates
|
GB9813540D0
(en)
|
1998-06-23 |
1998-08-19 |
Glaxo Group Ltd |
Chemical compounds
|
KR100563395B1
(ko)
|
1998-06-30 |
2006-03-23 |
다우 글로벌 테크놀로지스 인크. |
중합체 폴리올 및 이의 제조방법
|
DE69932173T2
(de)
|
1998-10-16 |
2007-06-06 |
Pfizer Inc. |
Adeninderivate
|
PT1141286E
(pt)
|
1998-12-14 |
2007-01-31 |
Genetics Inst Llc |
Cadeia de receptores de citocina
|
KR101077001B1
(ko)
|
1999-01-15 |
2011-10-26 |
제넨테크, 인크. |
효과기 기능이 변화된 폴리펩티드 변이체
|
WO2000044407A2
(en)
|
1999-02-01 |
2000-08-03 |
Amgen Canada |
Materials and methods to inhibit hodgkin and reed sternberg cell growth
|
AR022952A1
(es)
|
1999-03-19 |
2002-09-04 |
Smithkline Beecham Corp |
ANTICUERPO MONOCLONAL DE ROEDOR ESPECIFICAMENTE NEUTRALIZANTE PARA LA INTERLEUQUINA-18 HUMANA , UN FRAGMENTO FAB NEUTRALIZANTE o FRAGMENTO F(AB')2, UNA REGION DE COMPLEMENTARIEDAD DE CADENA LIGERA DE INMONOGLOBULINA(CDR), UNA MOLECULA DE ACIDO NUCLEICO, COMPOSICION FARMACEUTICA QUE LO COMPRENDE, EL
|
GB9913083D0
(en)
|
1999-06-04 |
1999-08-04 |
Novartis Ag |
Organic compounds
|
ES2571230T3
(es)
|
1999-04-09 |
2016-05-24 |
Kyowa Hakko Kirin Co Ltd |
Procedimiento para controlar la actividad de una molécula inmunofuncional
|
ATE299865T1
(de)
|
1999-05-04 |
2005-08-15 |
Schering Corp |
Piperazinderivate verwendbar als ccr5 antagonisten
|
TR200402496T2
(tr)
|
1999-05-04 |
2005-01-24 |
Schering Corporation |
CCR5 antagonistleri olarak yararlı piperidin türevleri.
|
YU25500A
(sh)
|
1999-05-11 |
2003-08-29 |
Pfizer Products Inc. |
Postupak za sintezu analoga nukleozida
|
US6683115B2
(en)
|
1999-06-02 |
2004-01-27 |
Theravance, Inc. |
β2-adrenergic receptor agonists
|
GB9913932D0
(en)
|
1999-06-15 |
1999-08-18 |
Pfizer Ltd |
Purine derivatives
|
US6322771B1
(en)
|
1999-06-18 |
2001-11-27 |
University Of Virginia Patent Foundation |
Induction of pharmacological stress with adenosine receptor agonists
|
ES2165768B1
(es)
|
1999-07-14 |
2003-04-01 |
Almirall Prodesfarma Sa |
Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
|
DE60037896D1
(de)
|
1999-07-29 |
2008-03-13 |
Medarex Inc |
Menschliche antikörper gegen her2/neu
|
MXPA02001830A
(es)
|
1999-08-21 |
2002-08-12 |
Byk Gulden Lomberg Chem Fab |
Combinacion sinergica de inhibidores de pde y agonista de beta 2 adrenoceptor.
|
CA2381770C
(en)
|
1999-08-24 |
2007-08-07 |
Medarex, Inc. |
Human ctla-4 antibodies and their uses
|
CO5180581A1
(es)
|
1999-09-30 |
2002-07-30 |
Pfizer Prod Inc |
Compuestos para el tratamiento de la isquemia ciones farmaceuticas que los contienen para el tratamiento de la isquemia
|
US6794132B2
(en)
|
1999-10-02 |
2004-09-21 |
Biosite, Inc. |
Human antibodies
|
GB9924363D0
(en)
|
1999-10-14 |
1999-12-15 |
Pfizer Central Res |
Purine derivatives
|
GB9924361D0
(en)
|
1999-10-14 |
1999-12-15 |
Pfizer Ltd |
Purine derivatives
|
OA11558A
(en)
|
1999-12-08 |
2004-06-03 |
Advanced Medicine Inc |
Beta 2-adrenergic receptor agonists.
|
US6645486B1
(en)
|
2000-01-25 |
2003-11-11 |
Ludwig Institute For Cancer Research |
Method of treatment with IL-9 conjugate
|
GB0003960D0
(en)
|
2000-02-18 |
2000-04-12 |
Pfizer Ltd |
Purine derivatives
|
GB0004016D0
(en)
|
2000-02-22 |
2000-04-12 |
Royal Brompton Hospital |
Biological material and uses thereof
|
WO2001083462A1
(de)
|
2000-04-27 |
2001-11-08 |
Boehringer Ingelheim Pharma Kg |
Neue, langwirksame betamimetika, verfahren zu deren herstellung und deren verwendung als arzneimittel
|
TWI227240B
(en)
|
2000-06-06 |
2005-02-01 |
Pfizer |
2-aminocarbonyl-9H-purine derivatives
|
GB0015727D0
(en)
|
2000-06-27 |
2000-08-16 |
Pfizer Ltd |
Purine derivatives
|
AP1420A
(en)
|
2000-06-27 |
2005-05-30 |
Salvat Lab Sa |
Carbamates derived from arylalkylamines.
|
GB0015876D0
(en)
|
2000-06-28 |
2000-08-23 |
Novartis Ag |
Organic compounds
|
DE10038639A1
(de)
|
2000-07-28 |
2002-02-21 |
Schering Ag |
Nichtsteroidale Entzündungshemmer
|
AR032471A1
(es)
|
2000-08-05 |
2003-11-12 |
Glaxo Group Ltd |
Derivado de androstano y solvatos del mismo, su uso para la fabricacion de medicamentos, composiciones farmaceuticas que los comprenden, procesos para preparar tales derivados, intermediarios utiles en la preparacion de tales derivados, procesos para preparar tales intermediarios, y compuestos inter
|
GB0022695D0
(en)
|
2000-09-15 |
2000-11-01 |
Pfizer Ltd |
Purine Derivatives
|
GB0028383D0
(en)
|
2000-11-21 |
2001-01-03 |
Novartis Ag |
Organic compounds
|
IL155977A0
(en)
|
2000-11-30 |
2003-12-23 |
Medarex Inc |
Transgenic transchromosomal rodents for making human antibodies
|
SI1345937T1
(sl)
|
2000-12-22 |
2006-02-28 |
Almirall Prodesfarma Ag |
Derivati kinulidinkarbamata in njihova uporaba kot M3 antagonisti
|
CA2433128C
(en)
|
2000-12-28 |
2010-05-25 |
Almirall Prodesfarma Ag |
Novel quinuclidine derivatives and medicinal compositions containing the same
|
GB0103630D0
(en)
|
2001-02-14 |
2001-03-28 |
Glaxo Group Ltd |
Chemical compounds
|
WO2002070490A1
(en)
|
2001-03-08 |
2002-09-12 |
Glaxo Group Limited |
Agonists of beta-adrenoceptors
|
EP1241176A1
(en)
|
2001-03-16 |
2002-09-18 |
Pfizer Products Inc. |
Purine derivatives for the treatment of ischemia
|
ATE381537T1
(de)
|
2001-03-22 |
2008-01-15 |
Glaxo Group Ltd |
Formanilid-derivative als beta2-adrenorezeptor- agonisten
|
CA2445839A1
(en)
|
2001-04-30 |
2002-11-07 |
Glaxo Group Limited |
Anti-inflammatory 17.beta.-carbothioate ester derivatives of androstane with a cyclic ester group in position 17.alpha
|
WO2002092780A2
(en)
|
2001-05-17 |
2002-11-21 |
Diversa Corporation |
Novel antigen binding molecules for therapeutic, diagnostic, prophylactic, enzymatic, industrial, and agricultural applications, and methods for generating and screening thereof
|
HUP0400029A2
(hu)
|
2001-05-25 |
2004-04-28 |
Pfizer Inc. |
Obstruktív légúti megbetegedések kezelésére szolgáló adenozin A2a receptor agonista és antikolinerg hatóanyag-kombináció és ezt tartalmazó gyógyszerkészítmény
|
US20040248867A1
(en)
|
2001-06-12 |
2004-12-09 |
Keith Biggadike |
Novel anti-inflammatory 17.alpha.-heterocyclic-esters of 17.beta.carbothioate androstane derivatives
|
DE10129392A1
(de)
|
2001-06-20 |
2003-01-02 |
Convenience Food Sys Wallau |
Werkzeug mit einem Sensorchip
|
EP1578910A4
(en)
|
2001-06-21 |
2008-06-04 |
Verenium Corp |
NITRILASES
|
US7049069B2
(en)
|
2001-07-17 |
2006-05-23 |
University Of Florida |
Detecting and treating reproductive tract disorders
|
KR100912324B1
(ko)
|
2001-09-14 |
2009-08-14 |
글락소 그룹 리미티드 |
호흡기 질환 치료용 펜에탄올아민 유도체
|
AU2002334969A1
(en)
|
2001-10-09 |
2003-04-22 |
Sylvie Barchechath |
Use of stat-6 inhibitors as therapeutic agents
|
RU2004110717A
(ru)
|
2001-10-17 |
2005-10-20 |
Юсиби, С.А. (Be) |
Производные хинуклидина, способы их получения и их применение в качестве и нгибиторов м2- и/или м3- мускариновых рецепторов
|
CA2842429A1
(en)
|
2001-10-19 |
2003-05-01 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of inflammatory bowel disorders
|
GB0125259D0
(en)
|
2001-10-20 |
2001-12-12 |
Glaxo Group Ltd |
Novel compounds
|
HUP0600342A3
(en)
|
2001-10-25 |
2011-03-28 |
Genentech Inc |
Glycoprotein compositions
|
US20040248260A1
(en)
|
2001-10-26 |
2004-12-09 |
Heavner George A. |
IL-13 mutein proteins, antibodies, compositions, methods and uses
|
WO2003035847A2
(en)
|
2001-10-26 |
2003-05-01 |
Centocor, Inc. |
Il-13 mutein proteins, antibodies, compositions, methods and uses
|
MY130622A
(en)
|
2001-11-05 |
2007-07-31 |
Novartis Ag |
Naphthyridine derivatives, their preparation and their use as phosphodiesterase isoenzyme 4 (pde4) inhibitors
|
WO2003042160A1
(en)
|
2001-11-13 |
2003-05-22 |
Theravance, Inc. |
Aryl aniline beta-2 adrenergic receptor agonists
|
TWI249515B
(en)
|
2001-11-13 |
2006-02-21 |
Theravance Inc |
Aryl aniline beta2 adrenergic receptor agonists
|
AU2002356759A1
(en)
|
2001-12-01 |
2003-06-17 |
Glaxo Group Limited |
17.alpha. -cyclic esters of 16-methylpregnan-3,20-dione as anti-inflammatory agents
|
US7452904B2
(en)
|
2001-12-20 |
2008-11-18 |
Chiesi Farmaceutici S.P.A. |
1-alkyl-1-azoniabicyclo' 2.2.2 octane carbamate derivatives and their use as muscarinic receptor antagonists
|
AU2003202044A1
(en)
|
2002-01-15 |
2003-09-09 |
Glaxo Group Limited |
17.alpha-cycloalkyl/cycloylkenyl esters of alkyl-or haloalkyl-androst-4-en-3-on-11.beta.,17.alpha.-diol 17.beta.-carboxylates as anti-inflammatory agents
|
WO2003062259A2
(en)
|
2002-01-21 |
2003-07-31 |
Glaxo Group Limited |
Non-aromatic 17.alpha.-esters of androstane-17.beta.-carboxylate esters as anti-inflammatory agents
|
GB0202216D0
(en)
|
2002-01-31 |
2002-03-20 |
Glaxo Group Ltd |
Novel compounds
|
GB0204719D0
(en)
|
2002-02-28 |
2002-04-17 |
Glaxo Group Ltd |
Medicinal compounds
|
WO2003074679A2
(en)
|
2002-03-01 |
2003-09-12 |
Xencor |
Antibody optimization
|
JP2005521717A
(ja)
|
2002-03-26 |
2005-07-21 |
ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド |
グルココルチコイドミメチックス、その製造方法、その医薬組成物、及び使用
|
NZ535889A
(en)
|
2002-03-26 |
2006-03-31 |
Boehringer Ingelheim Pharma |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
|
WO2003086451A1
(en)
*
|
2002-04-05 |
2003-10-23 |
Centocor, Inc. |
Asthma-related anti-il-13 immunoglobulin derived proteins, compositions, methods and uses
|
EP1496911B1
(en)
|
2002-04-10 |
2007-12-19 |
University Of Virginia Patent Foundation |
Use of a combination comprising a2a adenosine receptor agonists and anti-pathogenic agents for the treatment of inflammatory diseases
|
CA2481320A1
(en)
|
2002-04-11 |
2003-10-23 |
Merck & Co., Inc. |
1h-benzo[f]indazol-5-yl derivatives as selective glucocorticoid receptor modulators
|
ES2206021B1
(es)
|
2002-04-16 |
2005-08-01 |
Almirall Prodesfarma, S.A. |
Nuevos derivados de pirrolidinio.
|
US7271197B2
(en)
|
2002-04-25 |
2007-09-18 |
Glaxo Group Limited |
Phenethanolamine derivatives
|
WO2003092610A2
(en)
|
2002-05-01 |
2003-11-13 |
Regeneron Pharmaceuticals, Inc. |
Methods of using cytokine antagonists to treat hiv infection and aids
|
US6747043B2
(en)
|
2002-05-28 |
2004-06-08 |
Theravance, Inc. |
Alkoxy aryl β2 adrenergic receptor agonists
|
ES2201907B1
(es)
|
2002-05-29 |
2005-06-01 |
Almirall Prodesfarma, S.A. |
Nuevos derivados de indolilpiperidina como potentes agentes antihistaminicos y antialergicos.
|
US7186864B2
(en)
|
2002-05-29 |
2007-03-06 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
|
WO2003102157A2
(en)
|
2002-06-03 |
2003-12-11 |
Genentech, Inc. |
Synthetic antibody phage libraries
|
DE10224888A1
(de)
|
2002-06-05 |
2003-12-24 |
Merck Patent Gmbh |
Pyridazinderivate
|
US7074806B2
(en)
|
2002-06-06 |
2006-07-11 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
|
DE10225574A1
(de)
|
2002-06-10 |
2003-12-18 |
Merck Patent Gmbh |
Aryloxime
|
DE10227269A1
(de)
|
2002-06-19 |
2004-01-08 |
Merck Patent Gmbh |
Thiazolderivate
|
ATE356808T1
(de)
|
2002-06-25 |
2007-04-15 |
Merck Frosst Canada Ltd |
8-(biaryl)chinolin-pde4-inhibitoren
|
ES2204295B1
(es)
|
2002-07-02 |
2005-08-01 |
Almirall Prodesfarma, S.A. |
Nuevos derivados de quinuclidina-amida.
|
CA2490097A1
(en)
|
2002-07-02 |
2004-01-15 |
Merck Frosst Canada & Co. |
Di-aryl-substituted-ethane pyridone pde4 inhibitors
|
ES2518940T3
(es)
|
2002-07-08 |
2014-11-06 |
Pfizer Products Inc. |
Moduladores del receptor de glucocorticoides
|
GB0217225D0
(en)
|
2002-07-25 |
2002-09-04 |
Glaxo Group Ltd |
Medicinal compounds
|
PE20050130A1
(es)
|
2002-08-09 |
2005-03-29 |
Novartis Ag |
Compuestos organicos
|
RS51445B
(en)
|
2002-08-10 |
2011-04-30 |
Nycomed Gmbh. |
PYROLIDINDION SUBSTITUTED BY PIPERIDINE-PTHALAZONE AS PDE4 INHIBITORS
|
AU2003255376A1
(en)
|
2002-08-10 |
2004-03-11 |
Altana Pharma Ag |
Piperidine-derivatives as pde4 inhibitors
|
US20060167001A1
(en)
|
2002-08-10 |
2006-07-27 |
Sterk Jan G |
Pyridazinone-derivatives as pde4 inhibitors
|
JP2005538137A
(ja)
|
2002-08-10 |
2005-12-15 |
アルタナ ファルマ アクチエンゲゼルシャフト |
ピペリジン−n−オキシド誘導体
|
PL374014A1
(en)
|
2002-08-17 |
2005-09-19 |
Altana Pharma Ag |
Novel phenanthridines having pde 3/4 inhibiting properties
|
AU2003263216A1
(en)
|
2002-08-17 |
2004-03-11 |
Nycomed Gmbh |
Benzonaphthyridines with PDE 3/4 inhibiting activity
|
JP2006504678A
(ja)
|
2002-08-21 |
2006-02-09 |
ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド |
グルココルチコイドミメチックス、その製造方法、その医薬組成物、及び使用
|
SE0202483D0
(sv)
|
2002-08-21 |
2002-08-21 |
Astrazeneca Ab |
Chemical compounds
|
US7288562B2
(en)
|
2002-08-23 |
2007-10-30 |
Ranbaxy Laboratories Limited |
Fluoro and sulphonylamino containing 3,6-disubstituted azabicyclo (3.1.0) hexane derivatives as muscarinic receptor antagonists
|
JP4587295B2
(ja)
|
2002-08-29 |
2010-11-24 |
ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Pde4インヒビターとしての3−ヒドロキシ−6−フェニルフェナントリジン
|
EP1539164B1
(en)
|
2002-08-29 |
2006-12-20 |
ALTANA Pharma AG |
2-hydroxy-6-phenylphenanthridines as pde-4 inhibitors
|
JP4619786B2
(ja)
|
2002-08-29 |
2011-01-26 |
ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド |
炎症性、アレルギー性及び増殖性疾患の治療において糖質コルチコイドミメティックスとして使用するための3−(スルホンアミドエチル)−インドール誘導体
|
GB0220730D0
(en)
|
2002-09-06 |
2002-10-16 |
Glaxo Group Ltd |
Medicinal compounds
|
KR20050057408A
(ko)
|
2002-09-18 |
2005-06-16 |
오노 야꾸힝 고교 가부시키가이샤 |
트리아자스피로[5.5]운데칸 유도체 및 이를 유효 성분으로하는 약제
|
JP2006096662A
(ja)
|
2002-09-18 |
2006-04-13 |
Sumitomo Pharmaceut Co Ltd |
新規6−置換ウラシル誘導体及びアレルギー性疾患の治療剤
|
JP2004107299A
(ja)
|
2002-09-20 |
2004-04-08 |
Japan Energy Corp |
新規1−置換ウラシル誘導体及びアレルギー性疾患の治療剤
|
CA2499150A1
(en)
|
2002-09-20 |
2004-04-01 |
Merck & Co., Inc. |
Octahydro-2-h-naphtho[1,2-f] indole-4-carboxamide derivatives as selective glucocorticoid receptor modulators
|
DE10246374A1
(de)
|
2002-10-04 |
2004-04-15 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Betamimetika mit verlängerter Wirkungsdauer, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
|
EP1440966A1
(en)
|
2003-01-10 |
2004-07-28 |
Pfizer Limited |
Indole derivatives useful for the treatment of diseases
|
AU2003269316A1
(en)
|
2002-10-11 |
2004-05-04 |
Pfizer Inc. |
Indole derivatives as beta-2 agonists
|
ES2291733T3
(es)
|
2002-10-22 |
2008-03-01 |
Glaxo Group Limited |
Compuestos de ariletanolamina medicinales.
|
CN100532374C
(zh)
|
2002-10-23 |
2009-08-26 |
格兰马克药品有限公司 |
可用于治疗炎性和变应性病症的新的三环化合物:它们的制备方法以及包含它们的药物组合物
|
SI1556342T1
(sl)
|
2002-10-28 |
2008-08-31 |
Glaxo Group Ltd |
Fenetanolaminski derivat za zdravljenje respiratornih bolezni
|
GB0225030D0
(en)
|
2002-10-28 |
2002-12-04 |
Glaxo Group Ltd |
Medicinal compounds
|
GB0225287D0
(en)
|
2002-10-30 |
2002-12-11 |
Glaxo Group Ltd |
Novel compounds
|
GB0225535D0
(en)
|
2002-11-01 |
2002-12-11 |
Glaxo Group Ltd |
Medicinal compounds
|
GB0225540D0
(en)
|
2002-11-01 |
2002-12-11 |
Glaxo Group Ltd |
Medicinal compounds
|
DE10253220A1
(de)
|
2002-11-15 |
2004-05-27 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Dihydroxy-Methyl-Phenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
|
DE10253426B4
(de)
|
2002-11-15 |
2005-09-22 |
Elbion Ag |
Neue Hydroxyindole, deren Verwendung als Inhibitoren der Phosphodiesterase 4 und Verfahren zu deren Herstellung
|
DE10253282A1
(de)
|
2002-11-15 |
2004-05-27 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Arzneimittel zur Behandlung von chronisch obstruktiver Lungenerkrankung
|
CN1878795A
(zh)
|
2002-12-02 |
2006-12-13 |
阿布格尼克斯公司 |
针对磷脂酶a2的抗体及其应用
|
DE10261874A1
(de)
|
2002-12-20 |
2004-07-08 |
Schering Ag |
Nichtsteroidale Entzündungshemmer
|
EP1587818A4
(en)
|
2003-01-21 |
2010-10-13 |
Merck Sharp & Dohme |
17-CARBAMOYLOXY CORTISOL DERIVATIVES AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS
|
PE20040950A1
(es)
|
2003-02-14 |
2005-01-01 |
Theravance Inc |
DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
|
EP1460064A1
(en)
|
2003-03-14 |
2004-09-22 |
Pfizer Limited |
Indole-2-carboxamide derivatives useful as beta-2 agonists
|
WO2004082362A2
(en)
|
2003-03-18 |
2004-09-30 |
Nitto Denko Corporation |
Methods for extending amorphous photorefractive material lifetimes
|
US7317102B2
(en)
|
2003-04-01 |
2008-01-08 |
Theravance, Inc. |
Diarylmethyl and related compounds
|
BRPI0409198A
(pt)
|
2003-04-04 |
2006-05-02 |
Novartis Ag |
derivados quinolin-2-ona para o tratamento de doenças de vias aéreas
|
US7268147B2
(en)
|
2003-05-15 |
2007-09-11 |
Pfizer Inc |
Compounds useful for the treatment of diseases
|
WO2004106333A1
(en)
|
2003-05-28 |
2004-12-09 |
Theravance, Inc. |
Azabicycloalkane compounds as muscarinic receptor antagonists
|
JP2006526604A
(ja)
|
2003-06-04 |
2006-11-24 |
ファイザー・インク |
β−2アドレナリン受容体アゴニストとしての2−アミノ−ピリジン誘導体
|
GB0312832D0
(en)
|
2003-06-04 |
2003-07-09 |
Pfizer Ltd |
2-amino-pyridine derivatives useful for the treatment of diseases
|
GB0407315D0
(en)
|
2003-07-15 |
2004-05-05 |
Cambridge Antibody Tech |
Human antibody molecules
|
WO2005033121A2
(en)
|
2003-10-03 |
2005-04-14 |
King Pharmaceuticals Research & Development, Inc. |
Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs
|
GB0324654D0
(en)
|
2003-10-22 |
2003-11-26 |
Glaxo Group Ltd |
Medicinal compounds
|
GB0324886D0
(en)
|
2003-10-24 |
2003-11-26 |
Glaxo Group Ltd |
Medicinal compounds
|
PT1703893E
(pt)
|
2003-12-23 |
2012-06-01 |
Genentech Inc |
Novos anticorpos anti-il 13 e as respectivas utilizações
|
CA2557724A1
(en)
*
|
2004-02-27 |
2005-10-06 |
Centocor, Inc. |
Methods and compositions for treating il-13 related pathologies
|
US7501121B2
(en)
|
2004-06-17 |
2009-03-10 |
Wyeth |
IL-13 binding agents
|
US20070048785A1
(en)
|
2004-06-09 |
2007-03-01 |
Lin Laura L |
Anti-IL-13 antibodies and complexes
|
AR049390A1
(es)
*
|
2004-06-09 |
2006-07-26 |
Wyeth Corp |
Anticuerpos contra la interleuquina-13 humana y usos de los mismos
|
TWI307630B
(en)
|
2004-07-01 |
2009-03-21 |
Glaxo Group Ltd |
Immunoglobulins
|
US7563443B2
(en)
*
|
2004-09-17 |
2009-07-21 |
Domantis Limited |
Monovalent anti-CD40L antibody polypeptides and compositions thereof
|
JP2008520684A
(ja)
*
|
2004-11-17 |
2008-06-19 |
アブジェニックス・インコーポレーテッド |
Il−13に対する完全ヒトモノクローナル抗体
|
WO2006124451A2
(en)
|
2005-05-11 |
2006-11-23 |
Centocor, Inc. |
Anti-il-13 antibodies, compositions, methods and uses
|
EP1943359B1
(en)
|
2005-09-30 |
2011-06-29 |
Centocor Ortho Biotech Inc. |
Compositions and methods for il13 biomarkers
|
AU2006296399B2
(en)
|
2005-09-30 |
2011-01-20 |
Medimmune Limited |
Interleukin-13 antibody composition
|
KR20080049113A
(ko)
*
|
2005-10-21 |
2008-06-03 |
노파르티스 아게 |
Il-13에 대항한 인간 항체 및 치료적 용도
|
AU2006330858A1
(en)
|
2005-12-21 |
2007-07-05 |
Wyeth |
Protein formulations with reduced viscosity and uses thereof
|
GB0600488D0
(en)
|
2006-01-11 |
2006-02-22 |
Glaxo Group Ltd |
Immunoglobulins
|
TW200804593A
(en)
|
2006-01-24 |
2008-01-16 |
Domantis Ltd |
Fusion proteins that contain natural junctions
|
MX2013009529A
(es)
*
|
2011-02-17 |
2016-09-21 |
Univ Zuerich |
Tratamiento de enfermedad de crohn con fistulas.
|