LT3418300T - Neutralizuojantys antikūnai prieš gripo virusą a ir jų panaudojimas - Google Patents
Neutralizuojantys antikūnai prieš gripo virusą a ir jų panaudojimasInfo
- Publication number
- LT3418300T LT3418300T LTEP18180926.0T LT18180926T LT3418300T LT 3418300 T LT3418300 T LT 3418300T LT 18180926 T LT18180926 T LT 18180926T LT 3418300 T LT3418300 T LT 3418300T
- Authority
- LT
- Lithuania
- Prior art keywords
- influenza
- neutralizing anti
- virus antibodies
- antibodies
- virus
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title 1
- 206010022000 influenza Diseases 0.000 title 1
- 230000003472 neutralizing effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1018—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/11—Orthomyxoviridae, e.g. influenza virus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/10—Detection of antigens from microorganism in sample from host
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB2011/002329 WO2013011347A1 (en) | 2011-07-18 | 2011-07-18 | Neutralizing anti-influenza a virus antibodies and uses thereof |
| EP18180926.0A EP3418300B1 (en) | 2011-07-18 | 2011-07-18 | Neutralizing anti-influenza a virus antibodies and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT3418300T true LT3418300T (lt) | 2021-01-11 |
Family
ID=44993618
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP11784765.7T LT2734545T (lt) | 2011-07-18 | 2011-07-18 | Antikūnai, neutralizuojantys influenza a virusą, ir jų panaudojimo būdai |
| LTEP18180926.0T LT3418300T (lt) | 2011-07-18 | 2011-07-18 | Neutralizuojantys antikūnai prieš gripo virusą a ir jų panaudojimas |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP11784765.7T LT2734545T (lt) | 2011-07-18 | 2011-07-18 | Antikūnai, neutralizuojantys influenza a virusą, ir jų panaudojimo būdai |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US9587010B2 (lt) |
| EP (3) | EP3812397A1 (lt) |
| JP (1) | JP6035332B2 (lt) |
| CN (1) | CN103717617B (lt) |
| AU (1) | AU2011373387B2 (lt) |
| CA (1) | CA2841551C (lt) |
| DK (2) | DK2734545T3 (lt) |
| ES (2) | ES2841899T3 (lt) |
| HR (2) | HRP20190714T1 (lt) |
| HU (2) | HUE044089T2 (lt) |
| LT (2) | LT2734545T (lt) |
| MX (1) | MX352338B (lt) |
| PL (2) | PL2734545T3 (lt) |
| SI (2) | SI2734545T1 (lt) |
| WO (1) | WO2013011347A1 (lt) |
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| EP3812397A1 (en) | 2011-07-18 | 2021-04-28 | Institute for Research in Biomedicine | Neutralizing anti-influenza a virus antibodies and uses thereof |
| CN107417789A (zh) * | 2011-07-18 | 2017-12-01 | 生物医学学会 | 中和抗甲型流感病毒抗体及其用途 |
| US10130714B2 (en) | 2012-04-14 | 2018-11-20 | Academia Sinica | Enhanced anti-influenza agents conjugated with anti-inflammatory activity |
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| RU2553325C2 (ru) | 2008-07-25 | 2015-06-10 | Институт Фо Ресёч Ин Биомедицин | Нейтрализующие антитела против вируса гриппа а и их использование |
| ES2525346T3 (es) | 2008-10-22 | 2014-12-22 | Institute For Research In Biomedicine | Métodos para producir anticuerpos a partir de células plasmáticas |
| US9051359B2 (en) | 2009-03-30 | 2015-06-09 | Icahn School Of Medicine At Mount Sinai | Influenza virus vaccines and uses thereof |
| MX349924B (es) | 2009-06-24 | 2017-08-21 | Medicago Inc * | Partículas similares al virus de la influenza quiméricas que comprenden hemaglutinina. |
| EP3812397A1 (en) | 2011-07-18 | 2021-04-28 | Institute for Research in Biomedicine | Neutralizing anti-influenza a virus antibodies and uses thereof |
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2011
- 2011-07-18 EP EP20200200.2A patent/EP3812397A1/en active Pending
- 2011-07-18 DK DK11784765.7T patent/DK2734545T3/en active
- 2011-07-18 JP JP2014520738A patent/JP6035332B2/ja active Active
- 2011-07-18 HU HUE11784765A patent/HUE044089T2/hu unknown
- 2011-07-18 AU AU2011373387A patent/AU2011373387B2/en active Active
- 2011-07-18 EP EP18180926.0A patent/EP3418300B1/en active Active
- 2011-07-18 SI SI201131700T patent/SI2734545T1/sl unknown
- 2011-07-18 EP EP11784765.7A patent/EP2734545B1/en active Active
- 2011-07-18 PL PL11784765T patent/PL2734545T3/pl unknown
- 2011-07-18 CN CN201180072356.0A patent/CN103717617B/zh active Active
- 2011-07-18 ES ES18180926T patent/ES2841899T3/es active Active
- 2011-07-18 CA CA2841551A patent/CA2841551C/en active Active
- 2011-07-18 WO PCT/IB2011/002329 patent/WO2013011347A1/en active Application Filing
- 2011-07-18 ES ES11784765T patent/ES2732552T3/es active Active
- 2011-07-18 HU HUE18180926A patent/HUE051756T2/hu unknown
- 2011-07-18 PL PL18180926T patent/PL3418300T3/pl unknown
- 2011-07-18 MX MX2014000749A patent/MX352338B/es active IP Right Grant
- 2011-07-18 US US14/233,719 patent/US9587010B2/en active Active
- 2011-07-18 DK DK18180926.0T patent/DK3418300T3/da active
- 2011-07-18 LT LTEP11784765.7T patent/LT2734545T/lt unknown
- 2011-07-18 SI SI201131938T patent/SI3418300T1/sl unknown
- 2011-07-18 LT LTEP18180926.0T patent/LT3418300T/lt unknown
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2017
- 2017-01-20 US US15/411,677 patent/US20170204167A1/en not_active Abandoned
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2018
- 2018-11-01 US US16/178,497 patent/US10815294B2/en active Active
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2019
- 2019-04-16 HR HRP20190714TT patent/HRP20190714T1/hr unknown
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2020
- 2020-12-10 HR HRP20201975TT patent/HRP20201975T1/hr unknown
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