NO20064981L - Oksadiazolonderivater som PPAR delta agonister - Google Patents

Oksadiazolonderivater som PPAR delta agonister

Info

Publication number
NO20064981L
NO20064981L NO20064981A NO20064981A NO20064981L NO 20064981 L NO20064981 L NO 20064981L NO 20064981 A NO20064981 A NO 20064981A NO 20064981 A NO20064981 A NO 20064981A NO 20064981 L NO20064981 L NO 20064981L
Authority
NO
Norway
Prior art keywords
disorders
ppar
agonists
participate
compounds
Prior art date
Application number
NO20064981A
Other languages
English (en)
Inventor
Corinne Terrier
Baptiste Ronan
Stefanie Keil
Jean Merrill
Karen Chandross
Jochen Goerlitzer
Wolfgang Wendler
Daniel G Mcgarry
Maike Glien
Patrick Bernardelli
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of NO20064981L publication Critical patent/NO20064981L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Det beskrives oksadiazoloner og deres fysiologisk akseptable salter og fysiologisk funksjonelle derivater som viser PPAR 5 aktivitet. Det beskrives forbindelser med formel (I) der restene er som definert og deres fysiologisk akseptable salter samt fremgangsmåter for deres fremstilling. Forbindelsene er egnet for terapi og/eller prevensjon av forstyrrelser av fettsyremetabolisme og glukoseutnyttelsesforstyrrelser så vel som forstyrrelser der insulinresistens er involvert, neurodegenerative sykdommer og/eller demyelinerende forstyrrelser av sentral- og perifernervesystemet og/eller neurologiske forstyrrelser som involverer neuroinflammatoriske prosesser og/eller annen perifer neuropati.
NO20064981A 2004-04-01 2006-10-31 Oksadiazolonderivater som PPAR delta agonister NO20064981L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04007879A EP1586573B1 (en) 2004-04-01 2004-04-01 Oxadiazolones, processes for their preparation and their use as pharmaceuticals
PCT/EP2005/002950 WO2005097786A1 (en) 2004-04-01 2005-03-19 Oxadiazolone derivatives as ppar delta agonists

Publications (1)

Publication Number Publication Date
NO20064981L true NO20064981L (no) 2006-12-28

Family

ID=34924545

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20064981A NO20064981L (no) 2004-04-01 2006-10-31 Oksadiazolonderivater som PPAR delta agonister

Country Status (38)

Country Link
US (3) US20070179191A1 (no)
EP (3) EP1586573B1 (no)
JP (1) JP2007530612A (no)
KR (1) KR20060135857A (no)
CN (1) CN100582104C (no)
AR (1) AR050576A1 (no)
AT (1) ATE435225T1 (no)
AU (1) AU2005231916A1 (no)
BR (1) BRPI0509517A (no)
CA (1) CA2561627A1 (no)
CR (1) CR8572A (no)
CY (1) CY1109370T1 (no)
DE (2) DE602004004631D1 (no)
DK (1) DK1740583T3 (no)
DO (1) DOP2005000051A (no)
EC (1) ECSP066892A (no)
ES (1) ES2329484T3 (no)
GT (1) GT200500028A (no)
HK (1) HK1100408A1 (no)
HR (1) HRP20090493T1 (no)
IL (1) IL178056A0 (no)
MA (1) MA28495B1 (no)
MY (1) MY142431A (no)
NO (1) NO20064981L (no)
PA (1) PA8628701A1 (no)
PE (1) PE20060323A1 (no)
PL (1) PL1740583T3 (no)
PT (1) PT1740583E (no)
RS (1) RS51186B (no)
RU (1) RU2374243C2 (no)
SI (1) SI1740583T1 (no)
SV (1) SV2006002071A (no)
TN (1) TNSN06317A1 (no)
TW (1) TW200602342A (no)
UA (1) UA84203C2 (no)
UY (1) UY28837A1 (no)
WO (1) WO2005097786A1 (no)
ZA (1) ZA200606870B (no)

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KR20080048504A (ko) 2005-09-29 2008-06-02 사노피-아벤티스 페닐- 및 피리디닐-1,2,4-옥사디아졸론 유도체, 이의제조방법 및 약제로서의 이의 용도
BRPI0616477A2 (pt) 2005-09-29 2011-06-21 Sanofi Aventis derivados de 2-amintiazóis e 2-amino-oxazóis, processos para a sua preparação e seus usos
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ES2399147T3 (es) 2006-09-08 2013-03-26 Rhode Island Hospital Tratamiento, prevención y reversión de una enfermedad hepática alcohólica
WO2008030604A2 (en) 2006-09-08 2008-03-13 Rhode Island Hospital Treatment, prevention, and reversal of alcohol-induced brain disease
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Also Published As

Publication number Publication date
US20080255212A1 (en) 2008-10-16
MY142431A (en) 2010-11-30
CY1109370T1 (el) 2014-07-02
US20070179191A1 (en) 2007-08-02
TW200602342A (en) 2006-01-16
PL1740583T3 (pl) 2009-12-31
DOP2005000051A (es) 2005-12-15
BRPI0509517A (pt) 2007-09-11
PA8628701A1 (es) 2006-11-25
ECSP066892A (es) 2006-11-24
AU2005231916A1 (en) 2005-10-20
CN100582104C (zh) 2010-01-20
EP1740583A1 (en) 2007-01-10
ZA200606870B (en) 2008-04-30
HRP20090493T1 (en) 2009-10-31
WO2005097786A1 (en) 2005-10-20
RU2006138498A (ru) 2008-05-10
DK1740583T3 (da) 2009-10-19
US20080262052A1 (en) 2008-10-23
ES2329484T3 (es) 2009-11-26
AR050576A1 (es) 2006-11-08
SV2006002071A (es) 2006-01-30
CR8572A (es) 2007-12-04
EP1740583B1 (en) 2009-07-01
RS51186B (sr) 2010-10-31
US7709509B2 (en) 2010-05-04
MA28495B1 (fr) 2007-03-01
PT1740583E (pt) 2009-09-16
EP1586573A1 (en) 2005-10-19
PE20060323A1 (es) 2006-03-31
HK1100408A1 (en) 2007-09-21
EP2083006A1 (en) 2009-07-29
DE602005015204D1 (de) 2009-08-13
JP2007530612A (ja) 2007-11-01
GT200500028A (es) 2006-06-09
RU2374243C2 (ru) 2009-11-27
UA84203C2 (en) 2008-09-25
CA2561627A1 (en) 2005-10-20
KR20060135857A (ko) 2006-12-29
IL178056A0 (en) 2006-12-31
TNSN06317A1 (en) 2007-12-03
CN1938300A (zh) 2007-03-28
EP1586573B1 (en) 2007-02-07
SI1740583T1 (sl) 2009-12-31
DE602004004631D1 (de) 2007-03-22
ATE435225T1 (de) 2009-07-15
UY28837A1 (es) 2005-10-31

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