ATE435225T1 - Oxadiazolonderivate als ppar-delta-agonisten - Google Patents

Oxadiazolonderivate als ppar-delta-agonisten

Info

Publication number
ATE435225T1
ATE435225T1 AT05716233T AT05716233T ATE435225T1 AT E435225 T1 ATE435225 T1 AT E435225T1 AT 05716233 T AT05716233 T AT 05716233T AT 05716233 T AT05716233 T AT 05716233T AT E435225 T1 ATE435225 T1 AT E435225T1
Authority
AT
Austria
Prior art keywords
ppar
delta agonists
oxadiazolone derivatives
oxadiazolone
derivatives
Prior art date
Application number
AT05716233T
Other languages
English (en)
Inventor
Stefanie Keil
Wolfgang Wendler
Maike Glien
Jochen Goerlitzer
Karen Chandross
Daniel Mcgarry
Jean Merrill
Patrick Bernardelli
Baptiste Ronan
Corinne Terrier
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Application granted granted Critical
Publication of ATE435225T1 publication Critical patent/ATE435225T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT05716233T 2004-04-01 2005-03-19 Oxadiazolonderivate als ppar-delta-agonisten ATE435225T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04007879A EP1586573B1 (de) 2004-04-01 2004-04-01 Oxadiazolone, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Pharmazeutika
PCT/EP2005/002950 WO2005097786A1 (en) 2004-04-01 2005-03-19 Oxadiazolone derivatives as ppar delta agonists

Publications (1)

Publication Number Publication Date
ATE435225T1 true ATE435225T1 (de) 2009-07-15

Family

ID=34924545

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05716233T ATE435225T1 (de) 2004-04-01 2005-03-19 Oxadiazolonderivate als ppar-delta-agonisten

Country Status (38)

Country Link
US (3) US20070179191A1 (de)
EP (3) EP1586573B1 (de)
JP (1) JP2007530612A (de)
KR (1) KR20060135857A (de)
CN (1) CN100582104C (de)
AR (1) AR050576A1 (de)
AT (1) ATE435225T1 (de)
AU (1) AU2005231916A1 (de)
BR (1) BRPI0509517A (de)
CA (1) CA2561627A1 (de)
CR (1) CR8572A (de)
CY (1) CY1109370T1 (de)
DE (2) DE602004004631D1 (de)
DK (1) DK1740583T3 (de)
DO (1) DOP2005000051A (de)
EC (1) ECSP066892A (de)
ES (1) ES2329484T3 (de)
GT (1) GT200500028A (de)
HK (1) HK1100408A1 (de)
HR (1) HRP20090493T1 (de)
IL (1) IL178056A0 (de)
MA (1) MA28495B1 (de)
MY (1) MY142431A (de)
NO (1) NO20064981L (de)
PA (1) PA8628701A1 (de)
PE (1) PE20060323A1 (de)
PL (1) PL1740583T3 (de)
PT (1) PT1740583E (de)
RS (1) RS51186B (de)
RU (1) RU2374243C2 (de)
SI (1) SI1740583T1 (de)
SV (1) SV2006002071A (de)
TN (1) TNSN06317A1 (de)
TW (1) TW200602342A (de)
UA (1) UA84203C2 (de)
UY (1) UY28837A1 (de)
WO (1) WO2005097786A1 (de)
ZA (1) ZA200606870B (de)

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JP2009509988A (ja) 2005-09-29 2009-03-12 サノフィ−アベンティス フェニル−及びピリジニル−1,2,4−オキサジアゾロン誘導体、その製造方法、及び医薬品としてのその使用
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EP1931660B1 (de) * 2005-09-29 2012-08-01 Sanofi Phenyl-[1,2,4]-oxadiazol-5-on-derivate mit phenylgruppe, verfahren zu deren darstellung und deren verwendung als arzneimittel
JP2010502719A (ja) 2006-09-08 2010-01-28 ロード アイランド ホスピタル アルコール誘発性脳疾患の治療、予防および回復
JP5864077B2 (ja) 2006-09-08 2016-02-17 ロード アイランド ホスピタル アルコール誘発性肝疾患の治療、予防および回復
EP1932843A1 (de) * 2006-12-14 2008-06-18 sanofi-aventis Sulfonyl-Phenyl-2H-(1,2,4) Oxadiazol-5-one-Derivate, Verfahren zur Herstellung dafür und zur pharmazeutischen Verwendung damit
EP2288605B1 (de) * 2008-06-09 2014-06-25 Sanofi Annelierte pyrrolidinsulfonamide mit einer oxadiazolon-kopfgruppe, verfahren zu ihrer herstellung und ihre verwendung als pharmazeutika
WO2010000353A1 (en) * 2008-06-09 2010-01-07 Sanofi-Aventis Sulfonamides with heterocycle and oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals
US8329725B2 (en) 2008-06-09 2012-12-11 Sanofi Annelated pyrrolidin sulfonamides with oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals
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AU2010279964B2 (en) * 2009-08-05 2016-02-11 Daiichi Sankyo Company, Limited Amide derivative
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WO2015061481A1 (en) 2013-10-23 2015-04-30 Dara Biosciences, Inc. Methods of treating liquid tumors using compositions comprising spicamycin derivatives

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Also Published As

Publication number Publication date
EP1586573A1 (de) 2005-10-19
GT200500028A (es) 2006-06-09
MA28495B1 (fr) 2007-03-01
CR8572A (es) 2007-12-04
SI1740583T1 (sl) 2009-12-31
TW200602342A (en) 2006-01-16
EP2083006A1 (de) 2009-07-29
EP1740583A1 (de) 2007-01-10
HK1100408A1 (en) 2007-09-21
PT1740583E (pt) 2009-09-16
PL1740583T3 (pl) 2009-12-31
RS51186B (sr) 2010-10-31
SV2006002071A (es) 2006-01-30
US20080255212A1 (en) 2008-10-16
CY1109370T1 (el) 2014-07-02
DE602005015204D1 (de) 2009-08-13
IL178056A0 (en) 2006-12-31
ZA200606870B (en) 2008-04-30
DOP2005000051A (es) 2005-12-15
MY142431A (en) 2010-11-30
HRP20090493T1 (en) 2009-10-31
PE20060323A1 (es) 2006-03-31
AR050576A1 (es) 2006-11-08
CN100582104C (zh) 2010-01-20
DE602004004631D1 (de) 2007-03-22
RU2006138498A (ru) 2008-05-10
CN1938300A (zh) 2007-03-28
NO20064981L (no) 2006-12-28
KR20060135857A (ko) 2006-12-29
US20080262052A1 (en) 2008-10-23
EP1586573B1 (de) 2007-02-07
ECSP066892A (es) 2006-11-24
PA8628701A1 (es) 2006-11-25
UY28837A1 (es) 2005-10-31
DK1740583T3 (da) 2009-10-19
TNSN06317A1 (en) 2007-12-03
RU2374243C2 (ru) 2009-11-27
EP1740583B1 (de) 2009-07-01
ES2329484T3 (es) 2009-11-26
CA2561627A1 (en) 2005-10-20
AU2005231916A1 (en) 2005-10-20
BRPI0509517A (pt) 2007-09-11
UA84203C2 (en) 2008-09-25
US7709509B2 (en) 2010-05-04
WO2005097786A1 (en) 2005-10-20
JP2007530612A (ja) 2007-11-01
US20070179191A1 (en) 2007-08-02

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