ATE537149T1 - Sulfonyl-pyrazolinyl-1-carboxamidinderivate als 5-ht6-antagonisten - Google Patents
Sulfonyl-pyrazolinyl-1-carboxamidinderivate als 5-ht6-antagonistenInfo
- Publication number
- ATE537149T1 ATE537149T1 AT07820387T AT07820387T ATE537149T1 AT E537149 T1 ATE537149 T1 AT E537149T1 AT 07820387 T AT07820387 T AT 07820387T AT 07820387 T AT07820387 T AT 07820387T AT E537149 T1 ATE537149 T1 AT E537149T1
- Authority
- AT
- Austria
- Prior art keywords
- pyrazolinyl
- antagonists
- sulfonyl
- carboxamidine derivatives
- carboxamidine
- Prior art date
Links
Classifications
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- C07—ORGANIC CHEMISTRY
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- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
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- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
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Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US84640606P | 2006-09-22 | 2006-09-22 | |
EP06121087 | 2006-09-22 | ||
US90286507P | 2007-02-23 | 2007-02-23 | |
EP07102965 | 2007-02-23 | ||
PCT/EP2007/059944 WO2008034863A2 (en) | 2006-09-22 | 2007-09-20 | Sulfonylpyrazoline carboxamidine derivatives as 5-ht6 antagonists |
Publications (1)
Publication Number | Publication Date |
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ATE537149T1 true ATE537149T1 (de) | 2011-12-15 |
Family
ID=40225143
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT07820387T ATE537149T1 (de) | 2006-09-22 | 2007-09-20 | Sulfonyl-pyrazolinyl-1-carboxamidinderivate als 5-ht6-antagonisten |
Country Status (26)
Country | Link |
---|---|
US (3) | US7728018B2 (de) |
EP (1) | EP2069310B1 (de) |
JP (1) | JP5225280B2 (de) |
KR (1) | KR101433745B1 (de) |
CN (1) | CN101679279B (de) |
AR (1) | AR062907A1 (de) |
AT (1) | ATE537149T1 (de) |
AU (1) | AU2007298987B8 (de) |
BR (1) | BRPI0716860A2 (de) |
CA (1) | CA2662484C (de) |
CY (1) | CY1112418T1 (de) |
DK (1) | DK2069310T3 (de) |
EA (1) | EA021543B1 (de) |
ES (1) | ES2377996T3 (de) |
HK (1) | HK1137992A1 (de) |
HR (1) | HRP20120215T1 (de) |
IL (1) | IL197232A (de) |
MX (1) | MX2009003183A (de) |
MY (1) | MY147263A (de) |
NO (1) | NO20091485L (de) |
PL (1) | PL2069310T3 (de) |
PT (1) | PT2069310E (de) |
SA (1) | SA07280510B1 (de) |
SI (1) | SI2069310T1 (de) |
TW (1) | TWI428334B (de) |
WO (1) | WO2008034863A2 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7786144B2 (en) * | 2006-05-31 | 2010-08-31 | Solvay Pharmaceuticals B.V. | Sulphur containing pyrazole derivatives as selective cannabinoid CB1 receptor antagonists |
AR062907A1 (es) | 2006-09-22 | 2008-12-17 | Solvay Pharm Bv | Derivados de sulfonilpirazol y sulfonilpirazolincarboxamidina como antagonistas de 5-ht6 |
AR070898A1 (es) | 2008-03-18 | 2010-05-12 | Solvay Pharm Bv | Derivados de arilsulfonil pirazolin carboxamidina como antagonistas de 5-ht6 |
AR079935A1 (es) * | 2010-01-29 | 2012-02-29 | Abbott Healthcare Products Bv | Sintesis de derivados de pirazolin carboxamidina sustituida |
EP2763676B1 (de) * | 2011-10-03 | 2019-12-25 | The University of Utah Research Foundation | Verwendung von 5-ht6-rezeptorantagonisten zur linderung von kognitiven defiziten von down-syndrom |
FR2999574B1 (fr) * | 2012-12-18 | 2014-12-05 | Isochem Sa | Procede de synthese des hydrazines endocycliques |
EP3027613B1 (de) | 2013-07-25 | 2018-03-28 | Uniwersytet Jagiellonski | Pyrrolochinolin-derivate als 5-ht6-antagonisten, herstellungsverfahren und verwendung |
EP3109237A1 (de) * | 2015-06-22 | 2016-12-28 | AnaMar AB | Neuartige 5-ht2-antagonisten |
EP3112334A1 (de) * | 2015-06-29 | 2017-01-04 | DPx Fine Chemicals Austria GmbH & CoKG | Verfahren zur herstellung von 1-cyclopropyl-naphthalenen |
US11072761B2 (en) | 2017-08-08 | 2021-07-27 | S H Kelkar And Company Limited | Compositions comprising odorants |
WO2019180176A1 (en) | 2018-03-21 | 2019-09-26 | Spherium Biomed, S.L. | Composition for the treatment of schizophrenia and/or psychosis |
WO2022013225A1 (en) | 2020-07-13 | 2022-01-20 | Precirix N.V. | Antibody fragment against folr1 |
WO2023203135A1 (en) | 2022-04-22 | 2023-10-26 | Precirix N.V. | Improved radiolabelled antibody |
WO2023213801A1 (en) | 2022-05-02 | 2023-11-09 | Precirix N.V. | Pre-targeting |
Family Cites Families (8)
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JP2004500401A (ja) * | 2000-03-23 | 2004-01-08 | ソルベイ・フアーマシユーチカルズ・ベー・ブイ | Cb1−拮抗活性を有する4,5−ジヒドロ−1h−ピラゾール誘導体 |
AR034160A1 (es) | 2000-09-30 | 2004-02-04 | Gruenenthal Gmbh | Sulfonilguanidinas, medicamentos que contienen estos compuestos y el uso de sulfonilguanidinas |
HUP0402113A3 (en) | 2001-09-21 | 2012-05-29 | Solvay Pharm Bv | 4,5-dihydro-1h-pyrazole derivatives having cb1-antagonistic activity, preparation and use thereof |
SI1429761T1 (sl) * | 2001-09-21 | 2007-02-28 | Solvay Pharm Bv | Novi 4,5-dihidro-1h-pirazolni derivati s cb1-antagonisticno aktivnostjo |
CA2619480A1 (en) * | 2005-08-17 | 2007-02-22 | Solvay Pharmaceuticals Gmbh | Method of using potassium channel inhibiting compounds |
AR062907A1 (es) | 2006-09-22 | 2008-12-17 | Solvay Pharm Bv | Derivados de sulfonilpirazol y sulfonilpirazolincarboxamidina como antagonistas de 5-ht6 |
WO2008087123A2 (en) * | 2007-01-16 | 2008-07-24 | Solvay Pharmaceuticals B.V. | Use of 5-ht6 antagonists to prevent relapse into addiction |
US20080171779A1 (en) * | 2007-01-16 | 2008-07-17 | Solvay Pharmaceuticals B.V. | Use of 5-ht6 antagonists to prevent relapse into addiction |
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2007
- 2007-09-19 AR ARP070104142A patent/AR062907A1/es unknown
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- 2007-09-19 TW TW096134882A patent/TWI428334B/zh not_active IP Right Cessation
- 2007-09-20 PT PT07820387T patent/PT2069310E/pt unknown
- 2007-09-20 EA EA200970310A patent/EA021543B1/ru not_active IP Right Cessation
- 2007-09-20 AT AT07820387T patent/ATE537149T1/de active
- 2007-09-20 MY MYPI20091061A patent/MY147263A/en unknown
- 2007-09-20 SI SI200730822T patent/SI2069310T1/sl unknown
- 2007-09-20 MX MX2009003183A patent/MX2009003183A/es active IP Right Grant
- 2007-09-20 WO PCT/EP2007/059944 patent/WO2008034863A2/en active Application Filing
- 2007-09-20 PL PL07820387T patent/PL2069310T3/pl unknown
- 2007-09-20 KR KR1020097008264A patent/KR101433745B1/ko not_active IP Right Cessation
- 2007-09-20 CN CN2007800349063A patent/CN101679279B/zh not_active Expired - Fee Related
- 2007-09-20 BR BRPI0716860-8A patent/BRPI0716860A2/pt not_active IP Right Cessation
- 2007-09-20 EP EP07820387A patent/EP2069310B1/de active Active
- 2007-09-20 ES ES07820387T patent/ES2377996T3/es active Active
- 2007-09-20 DK DK07820387.4T patent/DK2069310T3/da active
- 2007-09-20 JP JP2009528720A patent/JP5225280B2/ja not_active Expired - Fee Related
- 2007-09-20 AU AU2007298987A patent/AU2007298987B8/en not_active Ceased
- 2007-09-20 CA CA2662484A patent/CA2662484C/en not_active Expired - Fee Related
- 2007-09-21 US US11/859,323 patent/US7728018B2/en not_active Expired - Fee Related
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2009
- 2009-02-24 IL IL197232A patent/IL197232A/en not_active IP Right Cessation
- 2009-04-16 NO NO20091485A patent/NO20091485L/no not_active Application Discontinuation
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2010
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2012
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2014
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