UY28837A1 - Oxadiazolonas procedimientos para su preparación y su uso como productos farmacéuticos. - Google Patents

Oxadiazolonas procedimientos para su preparación y su uso como productos farmacéuticos.

Info

Publication number
UY28837A1
UY28837A1 UY28837A UY28837A UY28837A1 UY 28837 A1 UY28837 A1 UY 28837A1 UY 28837 A UY28837 A UY 28837A UY 28837 A UY28837 A UY 28837A UY 28837 A1 UY28837 A1 UY 28837A1
Authority
UY
Uruguay
Prior art keywords
disorders
oxadiazolonas
procedures
preparation
pharmaceutical products
Prior art date
Application number
UY28837A
Other languages
English (en)
Inventor
Dr Stefanie Keil
Dr Jochen Goerlitzer
Dr Wolfgang Wendler
Dr Maike Glien
Daniel G Mcgarry
Jean Merrill
Karen Chandross
Patrick Bernardelli
Baptiste Ronan
Corinne Terrier
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of UY28837A1 publication Critical patent/UY28837A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La invención se refiere a oxadiazolonas de fórmula I en la que los radicales son como se han definido en la Memoria Descriptiva y a sus sales fisiológicamente aceptables y derivados fisiológicamente funcionales que muestran actividad agonista de PPAR-delta. Los compuestos son adecuados para el tratamiento y/o prevención de trastornos del metabolismo de ácidos grasos y trastornos de uso de la glucosa, así como trastornos en los que está implicada la resistencia a la insulina; enfermedades neurodegenerativas y/o trastornos de desmielinización de los sistemas nerviosos central y periférico, y/o enfermedades neurológicas que implican procesos neuroinflamatorios y/u otras neuropatías periféricas.
UY28837A 2004-04-01 2005-04-01 Oxadiazolonas procedimientos para su preparación y su uso como productos farmacéuticos. UY28837A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04007879A EP1586573B1 (en) 2004-04-01 2004-04-01 Oxadiazolones, processes for their preparation and their use as pharmaceuticals

Publications (1)

Publication Number Publication Date
UY28837A1 true UY28837A1 (es) 2005-10-31

Family

ID=34924545

Family Applications (1)

Application Number Title Priority Date Filing Date
UY28837A UY28837A1 (es) 2004-04-01 2005-04-01 Oxadiazolonas procedimientos para su preparación y su uso como productos farmacéuticos.

Country Status (38)

Country Link
US (3) US20070179191A1 (es)
EP (3) EP1586573B1 (es)
JP (1) JP2007530612A (es)
KR (1) KR20060135857A (es)
CN (1) CN100582104C (es)
AR (1) AR050576A1 (es)
AT (1) ATE435225T1 (es)
AU (1) AU2005231916A1 (es)
BR (1) BRPI0509517A (es)
CA (1) CA2561627A1 (es)
CR (1) CR8572A (es)
CY (1) CY1109370T1 (es)
DE (2) DE602004004631D1 (es)
DK (1) DK1740583T3 (es)
DO (1) DOP2005000051A (es)
EC (1) ECSP066892A (es)
ES (1) ES2329484T3 (es)
GT (1) GT200500028A (es)
HK (1) HK1100408A1 (es)
HR (1) HRP20090493T1 (es)
IL (1) IL178056A0 (es)
MA (1) MA28495B1 (es)
MY (1) MY142431A (es)
NO (1) NO20064981L (es)
PA (1) PA8628701A1 (es)
PE (1) PE20060323A1 (es)
PL (1) PL1740583T3 (es)
PT (1) PT1740583E (es)
RS (1) RS51186B (es)
RU (1) RU2374243C2 (es)
SI (1) SI1740583T1 (es)
SV (1) SV2006002071A (es)
TN (1) TNSN06317A1 (es)
TW (1) TW200602342A (es)
UA (1) UA84203C2 (es)
UY (1) UY28837A1 (es)
WO (1) WO2005097786A1 (es)
ZA (1) ZA200606870B (es)

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WO2007039177A2 (en) 2005-09-29 2007-04-12 Sanofi-Aventis Phenyl- and pyridinyl- 1, 2 , 4 - oxadiazolone derivatives, processes for their preparation and their use as pharmaceuticals
RU2008112199A (ru) 2005-09-29 2009-10-10 Санофи-Авентис (Fr) Производные 2-аминотиазолов и 2-аминооксазолов, способы их получения и их применение в качестве лекарственных препаратов
PL1931660T3 (pl) * 2005-09-29 2012-12-31 Sanofi Sa Pochodne fenylo-[1,2,4]-oksadiazol-5-onu z grupą fenylową, sposoby ich wytwarzania i ich zastosowanie jako środków farmaceutycznych
JP5864077B2 (ja) 2006-09-08 2016-02-17 ロード アイランド ホスピタル アルコール誘発性肝疾患の治療、予防および回復
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EP2288605B1 (en) * 2008-06-09 2014-06-25 Sanofi Annelated pyrrolidin sulfonamides with oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals
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Also Published As

Publication number Publication date
PA8628701A1 (es) 2006-11-25
RU2006138498A (ru) 2008-05-10
ES2329484T3 (es) 2009-11-26
PE20060323A1 (es) 2006-03-31
HK1100408A1 (en) 2007-09-21
TNSN06317A1 (en) 2007-12-03
US20070179191A1 (en) 2007-08-02
US7709509B2 (en) 2010-05-04
MY142431A (en) 2010-11-30
EP1586573A1 (en) 2005-10-19
IL178056A0 (en) 2006-12-31
SI1740583T1 (sl) 2009-12-31
EP1740583B1 (en) 2009-07-01
CR8572A (es) 2007-12-04
AR050576A1 (es) 2006-11-08
ECSP066892A (es) 2006-11-24
JP2007530612A (ja) 2007-11-01
RS51186B (sr) 2010-10-31
CN100582104C (zh) 2010-01-20
EP1586573B1 (en) 2007-02-07
BRPI0509517A (pt) 2007-09-11
CA2561627A1 (en) 2005-10-20
SV2006002071A (es) 2006-01-30
GT200500028A (es) 2006-06-09
MA28495B1 (fr) 2007-03-01
NO20064981L (no) 2006-12-28
PL1740583T3 (pl) 2009-12-31
RU2374243C2 (ru) 2009-11-27
HRP20090493T1 (en) 2009-10-31
US20080255212A1 (en) 2008-10-16
AU2005231916A1 (en) 2005-10-20
US20080262052A1 (en) 2008-10-23
WO2005097786A1 (en) 2005-10-20
DOP2005000051A (es) 2005-12-15
TW200602342A (en) 2006-01-16
KR20060135857A (ko) 2006-12-29
DK1740583T3 (da) 2009-10-19
DE602004004631D1 (de) 2007-03-22
ZA200606870B (en) 2008-04-30
UA84203C2 (en) 2008-09-25
ATE435225T1 (de) 2009-07-15
CY1109370T1 (el) 2014-07-02
EP2083006A1 (en) 2009-07-29
EP1740583A1 (en) 2007-01-10
DE602005015204D1 (de) 2009-08-13
CN1938300A (zh) 2007-03-28
PT1740583E (pt) 2009-09-16

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