NO20060542L - Modifiserte human IGF-1R antistoffer - Google Patents
Modifiserte human IGF-1R antistofferInfo
- Publication number
- NO20060542L NO20060542L NO20060542A NO20060542A NO20060542L NO 20060542 L NO20060542 L NO 20060542L NO 20060542 A NO20060542 A NO 20060542A NO 20060542 A NO20060542 A NO 20060542A NO 20060542 L NO20060542 L NO 20060542L
- Authority
- NO
- Norway
- Prior art keywords
- antibodies
- human igf
- modified human
- igf
- human
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Transplantation (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49520003P | 2003-08-13 | 2003-08-13 | |
PCT/IB2004/002555 WO2005016967A2 (en) | 2003-08-13 | 2004-08-03 | Modified human igf-1r antibodies |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20060542L true NO20060542L (no) | 2006-05-03 |
Family
ID=34193291
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20060542A NO20060542L (no) | 2003-08-13 | 2006-02-02 | Modifiserte human IGF-1R antistoffer |
Country Status (37)
Country | Link |
---|---|
US (2) | US7371378B2 (nl) |
EP (1) | EP1656391B1 (nl) |
JP (1) | JP4638870B2 (nl) |
KR (1) | KR100825156B1 (nl) |
CN (1) | CN1835975B (nl) |
AP (1) | AP2006003510A0 (nl) |
AR (1) | AR045247A1 (nl) |
AT (1) | ATE484525T1 (nl) |
AU (1) | AU2004265152A1 (nl) |
BR (1) | BRPI0413466A (nl) |
CA (1) | CA2535071A1 (nl) |
CL (1) | CL2004002035A1 (nl) |
CR (1) | CR8233A (nl) |
DE (1) | DE602004029581D1 (nl) |
DK (1) | DK1656391T3 (nl) |
EA (1) | EA200600234A1 (nl) |
EC (1) | ECSP066359A (nl) |
ES (1) | ES2351395T3 (nl) |
GT (1) | GT200400158A (nl) |
IL (1) | IL173273A (nl) |
IS (1) | IS8266A (nl) |
MA (1) | MA27988A1 (nl) |
MX (1) | MXPA06001634A (nl) |
NL (1) | NL1026829C2 (nl) |
NO (1) | NO20060542L (nl) |
OA (1) | OA13234A (nl) |
PA (1) | PA8608801A1 (nl) |
PE (1) | PE20050339A1 (nl) |
PL (1) | PL1656391T3 (nl) |
PT (1) | PT1656391E (nl) |
RS (1) | RS20060099A (nl) |
TN (1) | TNSN06050A1 (nl) |
TW (1) | TWI294915B (nl) |
UA (1) | UA85058C2 (nl) |
UY (1) | UY28464A1 (nl) |
WO (1) | WO2005016967A2 (nl) |
ZA (1) | ZA200601231B (nl) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUP0302525A2 (hu) | 2001-01-05 | 2003-10-28 | Abgenix, Inc. | Az inzulinszerű növekedési faktor I receptor elleni ellenanyagok |
CA2484000A1 (en) * | 2002-05-24 | 2003-12-04 | Schering Corporation | Neutralizing human anti-igfr antibody |
EP2365001A3 (en) * | 2003-05-01 | 2012-03-28 | Imclone LLC | Fully human antibodies directed against the human insulin-like growth factor-1 receptor |
RS20060099A (en) * | 2003-08-13 | 2008-08-07 | Pfizer Products Inc., | Modified human igf-1r antibodies |
JP2007510434A (ja) | 2003-11-12 | 2007-04-26 | シェーリング コーポレイション | 多重遺伝子発現のためのプラスミドシステム |
PE20050928A1 (es) | 2003-11-21 | 2005-11-08 | Schering Corp | Combinaciones terapeuticas de anticuerpo anti-igfr1 |
CN101014365B (zh) * | 2004-07-16 | 2011-04-13 | 辉瑞产品公司 | 使用抗-igf-1r抗体联合治疗非血液的恶性肿瘤 |
FR2873699B1 (fr) * | 2004-07-29 | 2009-08-21 | Pierre Fabre Medicament Sa | Nouveaux anticorps anti igf ir rt leurs utilisations |
MX2007006640A (es) | 2004-12-03 | 2007-06-19 | Schering Corp | Biomarcadores para la preseleccion de pacientes para la terapia con anti-receptor 1 del factor de crecimiento similar a la insulina. |
MY146381A (en) | 2004-12-22 | 2012-08-15 | Amgen Inc | Compositions and methods relating relating to anti-igf-1 receptor antibodies |
GB0500417D0 (en) * | 2005-01-10 | 2005-02-16 | Cambridge Antibody Tech | Method of mutagenesis |
EP1879587A2 (en) * | 2005-04-15 | 2008-01-23 | Schering Corporation | Methods and compositions for treating or preventing cancer |
US20060286103A1 (en) * | 2005-06-15 | 2006-12-21 | Parag Kolhe | Stable antibody formulation |
ES2452115T3 (es) * | 2005-06-17 | 2014-03-31 | Imclone Llc | Un anticuerpo anti-PDGFRalfa para su uso en el tratamiento de cáncer de huesos metastásico |
FR2888850B1 (fr) * | 2005-07-22 | 2013-01-11 | Pf Medicament | Nouveaux anticorps anti-igf-ir et leurs applications |
AP2008004569A0 (en) * | 2006-02-03 | 2008-08-31 | Imclone Systems Inc | IGR-IR antagonists as adjuvants for treatment of prostrate cancer |
EP1998806A1 (en) * | 2006-03-28 | 2008-12-10 | F. Hoffmann-Roche AG | Anti-igf-1r human monoclonal antibody formulation |
US7846724B2 (en) | 2006-04-11 | 2010-12-07 | Hoffmann-La Roche Inc. | Method for selecting CHO cell for production of glycosylated antibodies |
CA2653745C (en) * | 2006-06-02 | 2013-11-19 | Pfizer Products Inc. | Circulating tumor cell assay |
WO2008079849A2 (en) * | 2006-12-22 | 2008-07-03 | Genentech, Inc. | Antibodies to insulin-like growth factor receptor |
GB0702888D0 (en) * | 2007-02-14 | 2007-03-28 | Glaxo Group Ltd | Novel Antibodies |
AU2012203443B2 (en) * | 2007-03-02 | 2014-03-06 | Amgen Inc. | Methods and compositions for treating tumor diseases |
CA2679548C (en) * | 2007-03-02 | 2015-01-27 | Amgen Inc. | Methods and compositions for treating tumor diseases |
KR20090113340A (ko) * | 2007-03-22 | 2009-10-29 | 임클론 엘엘씨 | 안정한 항체 제제 |
US8492328B2 (en) | 2007-05-17 | 2013-07-23 | Bristol-Myers Squibb Company | Biomarkers and methods for determining sensitivity to insulin growth factor-1 receptor modulators |
CN101903401B (zh) | 2007-12-21 | 2013-06-05 | 罗切格利卡特公司 | 抗体的稳定性试验 |
EP2259797A2 (en) * | 2008-03-25 | 2010-12-15 | Schering Corporation | Methods for treating or preventing colorectal cancer |
MX2010012064A (es) * | 2008-05-05 | 2010-12-06 | Schering Corp | Uso secuencial de agentes quimioterapeuticos citotoxicos para el tratamiento de cancer. |
EP2356154A4 (en) * | 2008-11-06 | 2012-12-19 | Alexion Pharma Inc | DEVELOPMENT OF REDUCED IMMUNOGENICITY ANTIBODIES AND METHODS OF MANUFACTURING THEREOF |
JP2012518657A (ja) | 2009-02-25 | 2012-08-16 | オーエスアイ・ファーマシューティカルズ,エルエルシー | 併用抗癌治療 |
EP2236139A1 (en) | 2009-03-31 | 2010-10-06 | F. Hoffmann-La Roche AG | Combination therapy of erlotinib with an anti-IGF-1R antibody, which does not inhibit binding of insulin to the insulin receptor |
WO2010146059A2 (en) | 2009-06-16 | 2010-12-23 | F. Hoffmann-La Roche Ag | Biomarkers for igf-1r inhibitor therapy |
TWI513465B (zh) | 2009-06-25 | 2015-12-21 | Regeneron Pharma | 以dll4拮抗劑與化學治療劑治療癌症之方法 |
EP4406615A2 (en) | 2009-10-26 | 2024-07-31 | F. Hoffmann-La Roche AG | Method for the production of a glycosylated immunoglobulin |
WO2011053779A2 (en) | 2009-10-30 | 2011-05-05 | Bristol-Myers Squibb Company | Methods for treating cancer in patients having igf-1r inhibitor resistance |
MX352871B (es) * | 2009-12-23 | 2017-12-13 | Esbatech Alcon Biomed Res Unit | Método para disminuir inmunogenicidad. |
AU2014262201B2 (en) * | 2009-12-23 | 2016-09-15 | Novartis Ag | Method for decreasing immunogenicity |
WO2011101328A2 (en) | 2010-02-18 | 2011-08-25 | Roche Glycart Ag | Treatment with a humanized igg class anti egfr antibody and an antibody against insulin like growth factor 1 receptor |
WO2011161119A1 (en) | 2010-06-22 | 2011-12-29 | F. Hoffmann-La Roche Ag | Antibodies against insulin-like growth factor i receptor and uses thereof |
EP2593142B8 (en) | 2010-07-12 | 2018-12-26 | Pfizer Healthcare Ireland | Multifunctional antibody conjugates |
US20140037642A1 (en) | 2011-02-02 | 2014-02-06 | Amgen Inc. | Methods and compositions relating to inhibition of igf-1r |
EP3536708A1 (en) | 2011-04-19 | 2019-09-11 | Pfizer Inc | Combinations of anti-4-1bb antibodies and adcc-inducing antibodies for the treatment of cancer |
US20140309229A1 (en) | 2011-10-13 | 2014-10-16 | Bristol-Myers Squibb Company | Methods for selecting and treating cancer in patients with igf-1r/ir inhibitors |
EP2802355B1 (en) | 2012-01-09 | 2018-09-05 | CovX Technologies Ireland Limited | Mutant antibodies and conjugation thereof |
EP2631653A1 (en) | 2012-02-24 | 2013-08-28 | Charité - Universitätsmedizin Berlin | Identification of modulators of binding properties of antibodies reactive with a member of the insulin receptor family |
WO2013152252A1 (en) | 2012-04-06 | 2013-10-10 | OSI Pharmaceuticals, LLC | Combination anti-cancer therapy |
WO2014074528A2 (en) * | 2012-11-06 | 2014-05-15 | Medimmune, Llc | Combination therapies using anti-pseudomonas psl and pcrv binding molecules |
KR20210094669A (ko) | 2013-04-29 | 2021-07-29 | 에프. 호프만-라 로슈 아게 | 인간 fcrn-결합 변형된 항체 및 사용 방법 |
CN103319598B (zh) * | 2013-05-13 | 2014-10-22 | 杭州德同生物技术有限公司 | 抗胰岛素样生长因子-1受体抗体及其编码基因和应用 |
MX2016008782A (es) | 2014-01-15 | 2016-09-08 | Hoffmann La Roche | Variantes de region fc con union mejorada de la proteina a. |
BR112019013953A2 (pt) | 2017-01-06 | 2020-02-11 | Abl Bio Inc. | Anticorpo anti-a-syn e uso do mesmo |
EP3484925B1 (en) * | 2017-07-27 | 2020-05-27 | iTeos Therapeutics SA | Anti-tigit antibodies |
US12071483B1 (en) | 2017-12-14 | 2024-08-27 | Abl Bio Inc. | Bispecific antibody to alpha-synuclein/insulin-like growth factor 1 receptor and use thereof |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6054561A (en) * | 1984-02-08 | 2000-04-25 | Chiron Corporation | Antigen-binding sites of antibody molecules specific for cancer antigens |
GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
US6657103B1 (en) * | 1990-01-12 | 2003-12-02 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
GB9203459D0 (en) * | 1992-02-19 | 1992-04-08 | Scotgen Ltd | Antibodies with germ-line variable regions |
US5863949A (en) | 1995-03-08 | 1999-01-26 | Pfizer Inc | Arylsulfonylamino hydroxamic acid derivatives |
WO1996033172A1 (en) | 1995-04-20 | 1996-10-24 | Pfizer Inc. | Arylsulfonyl hydroxamic acid derivatives as mmp and tnf inhibitors |
CA2761116A1 (en) | 1995-04-27 | 1996-10-31 | Amgen Fremont Inc. | Human antibodies derived from immunized xenomice |
IL118626A0 (en) * | 1996-06-11 | 1996-10-16 | Xtl Biopharmaceuticals Limited | Anti HBV antibody |
KR20000067904A (ko) | 1996-07-18 | 2000-11-25 | 디. 제이. 우드, 스피겔 알렌 제이 | 매트릭스 메탈로프로테아제의 포스피네이트계 억제제 |
JP2000501423A (ja) | 1996-08-23 | 2000-02-08 | ファイザー インク. | アリールスルホニルアミノヒドロキサム酸誘導体 |
IL139707A0 (en) | 1998-05-15 | 2002-02-10 | Imclone Systems Inc | Treatment of human tumors with radiation and inhibitors of growth factor receptor tyrosine kinases |
US6682736B1 (en) * | 1998-12-23 | 2004-01-27 | Abgenix, Inc. | Human monoclonal antibodies to CTLA-4 |
TR200802278T2 (tr) | 1999-03-25 | 2008-08-21 | Abbott Gmbh & Co. Kg | Beşeri IL-12'yi bağlayan beşeri antikorlar ve bunları üretmek için yöntemler. |
ES1042735Y (es) | 1999-04-07 | 2000-02-16 | Martinez Fernando Martinez | Vehiculo tripersonal de accionamiento a pedales. |
US20030165502A1 (en) | 2000-06-13 | 2003-09-04 | City Of Hope | Single-chain antibodies against human insulin-like growth factor I receptor: expression, purification, and effect on tumor growth |
DE10033869C2 (de) | 2000-07-12 | 2003-07-31 | Karlsruhe Forschzent | HTS-Kryomagnet und Aufmagnetisierungsverfahren |
HUP0302525A2 (hu) | 2001-01-05 | 2003-10-28 | Abgenix, Inc. | Az inzulinszerű növekedési faktor I receptor elleni ellenanyagok |
EP1361893B1 (en) | 2001-02-19 | 2012-10-24 | Merck Patent GmbH | Modified anti-egfr antibodies with reduced immunogenicity |
ES2427964T3 (es) | 2002-01-18 | 2013-11-05 | Pierre Fabre Medicament | Nuevos anticuerpos anti-IGF-IR y sus aplicaciones |
ATE444972T1 (de) | 2002-04-30 | 2009-10-15 | Kyowa Hakko Kirin Co Ltd | ANTIKÖRPER GEGEN DEN HUMANEN ßINSULIN-LIKEß WACHSTUMSFAKTOR |
CA2484000A1 (en) | 2002-05-24 | 2003-12-04 | Schering Corporation | Neutralizing human anti-igfr antibody |
GB0212303D0 (en) | 2002-05-28 | 2002-07-10 | Isis Innovation | Molecular targetting of IGF-1 receptor |
US7538195B2 (en) | 2002-06-14 | 2009-05-26 | Immunogen Inc. | Anti-IGF-I receptor antibody |
NZ582210A (en) | 2003-02-13 | 2011-04-29 | Pfizer Prod Inc | Uses of anti-insulin-like growth factor I receptor antibodies |
CA2518980A1 (en) | 2003-03-14 | 2004-09-30 | Pharmacia Corporation | Antibodies to igf-i receptor for the treatment of cancers |
CA2519113C (en) | 2003-04-02 | 2012-06-05 | F. Hoffmann-La Roche Ag | Antibodies against insulin-like growth factor i receptor and uses thereof |
RS20060099A (en) * | 2003-08-13 | 2008-08-07 | Pfizer Products Inc., | Modified human igf-1r antibodies |
-
2004
- 2004-08-03 RS YUP-2006/0099A patent/RS20060099A/sr unknown
- 2004-08-03 AT AT04744197T patent/ATE484525T1/de active
- 2004-08-03 CN CN2004800230991A patent/CN1835975B/zh not_active Expired - Fee Related
- 2004-08-03 UA UAA200601349A patent/UA85058C2/ru unknown
- 2004-08-03 OA OA1200600046A patent/OA13234A/en unknown
- 2004-08-03 DK DK04744197.7T patent/DK1656391T3/da active
- 2004-08-03 EA EA200600234A patent/EA200600234A1/ru unknown
- 2004-08-03 ES ES04744197T patent/ES2351395T3/es not_active Expired - Lifetime
- 2004-08-03 EP EP04744197A patent/EP1656391B1/en not_active Expired - Lifetime
- 2004-08-03 AU AU2004265152A patent/AU2004265152A1/en not_active Abandoned
- 2004-08-03 DE DE602004029581T patent/DE602004029581D1/de not_active Expired - Lifetime
- 2004-08-03 WO PCT/IB2004/002555 patent/WO2005016967A2/en active Application Filing
- 2004-08-03 KR KR1020067002957A patent/KR100825156B1/ko not_active IP Right Cessation
- 2004-08-03 BR BRPI0413466-4A patent/BRPI0413466A/pt not_active IP Right Cessation
- 2004-08-03 JP JP2006523070A patent/JP4638870B2/ja not_active Expired - Fee Related
- 2004-08-03 CA CA002535071A patent/CA2535071A1/en not_active Abandoned
- 2004-08-03 PT PT04744197T patent/PT1656391E/pt unknown
- 2004-08-03 PL PL04744197T patent/PL1656391T3/pl unknown
- 2004-08-03 MX MXPA06001634A patent/MXPA06001634A/es unknown
- 2004-08-03 AP AP2006003510A patent/AP2006003510A0/xx unknown
- 2004-08-09 PE PE2004000773A patent/PE20050339A1/es not_active Application Discontinuation
- 2004-08-10 CL CL200402035A patent/CL2004002035A1/es unknown
- 2004-08-11 AR ARP040102870A patent/AR045247A1/es active IP Right Grant
- 2004-08-11 UY UY28464A patent/UY28464A1/es not_active Application Discontinuation
- 2004-08-12 NL NL1026829A patent/NL1026829C2/nl not_active IP Right Cessation
- 2004-08-12 GT GT200400158A patent/GT200400158A/es unknown
- 2004-08-12 US US10/917,073 patent/US7371378B2/en not_active Expired - Fee Related
- 2004-08-12 PA PA20048608801A patent/PA8608801A1/es unknown
- 2004-08-12 TW TW093124269A patent/TWI294915B/zh not_active IP Right Cessation
-
2006
- 2006-01-19 IL IL173273A patent/IL173273A/en not_active IP Right Cessation
- 2006-01-26 IS IS8266A patent/IS8266A/is unknown
- 2006-02-02 NO NO20060542A patent/NO20060542L/no not_active Application Discontinuation
- 2006-02-10 EC EC2006006359A patent/ECSP066359A/es unknown
- 2006-02-10 ZA ZA200601231A patent/ZA200601231B/en unknown
- 2006-02-13 CR CR8233A patent/CR8233A/es not_active Application Discontinuation
- 2006-02-13 MA MA28790A patent/MA27988A1/fr unknown
- 2006-02-13 TN TNP2006000050A patent/TNSN06050A1/fr unknown
-
2008
- 2008-03-03 US US12/041,341 patent/US7575746B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20060542L (no) | Modifiserte human IGF-1R antistoffer | |
NO20082167L (no) | Anti-Myostatin-antistoffer | |
EA201070148A1 (ru) | Соединения и способы модулирования фарнезоидного рецептора x (fxr) | |
DE602005014566D1 (de) | Chinolinon-carboxamid-verbindungen | |
NO20073182L (no) | Indazol-karboksamidforbindelser | |
CA2620129C (en) | Diaminopyrimidines as p2x3 and p2x2/3 modulators | |
ATE441646T1 (de) | 5-ht4-rezeptoragonistenverbindungen | |
NO20061845L (no) | Fenyl-piperazinderivater som modulatorer for muskarine reseptorer | |
NO20064826L (no) | Indazoler, benzotiazoler, benzoisotiazoler, benzisoksazoler og fremstilling og anvendelse derav | |
EA200801372A1 (ru) | Способы получения замещенных пиримидинов | |
NO20083501L (no) | Azaindoler som er anvendelige som inhibitorer for Janus-kinaser | |
NO20063479L (no) | Fosfonater, monofosfonamidater og bis-fosfonamidater for behandling av virussykdommer | |
EA201100524A1 (ru) | Азаиндазолы в качестве антагонистов рецептора ccr1 | |
NO20084878L (no) | Humanisert C-kit antistoff | |
EA200501430A1 (ru) | Лиганды каннабиноидных рецепторов и их применение | |
EA200702346A1 (ru) | КРИСТАЛЛИЧЕСКАЯ ФОРМА 1-ХЛОР-4-(β-D-ГЛЮКОПИРАНОЗ-1-ИЛ)-2-[4-((S)-ТЕТРАГИДРОФУРАН-3-ИЛОКСИ)БЕНЗИЛ]БЕНЗОЛА, СПОСОБ ЕЁ ПОЛУЧЕНИЯ И ЕЁ ПРИМЕНЕНИЕ ДЛЯ ПРИГОТОВЛЕНИЯ ЛЕКАРСТВЕННЫХ СРЕДСТВ | |
NO20091413L (no) | WNT-antagonister og deres anvendelse i diagnostiseringen og behandlingen av WNT-medierte forstyrrelser | |
DE602005027258D1 (de) | Humane monoklonale antikörper gegen hendra- und nipah-viren | |
MX2007011848A (es) | Antagonistas del receptor de procineticina i. | |
MX2007011847A (es) | Derivados de pirimidindiona como antagonistas del receptor de procineticina 2. | |
CY1109808T1 (el) | Αρυλινδενο-πυριδινες και αρυλινδενο-πυριμιδινες και η χρηση τους ως ανταγωνιστων των υποδοχεων αδενοσινης α2α | |
NO20070502L (no) | Azaindoler nyttige som inhibitorer av proteinkinaser | |
WO2020097127A3 (en) | B-cell activating cd73 antibodies | |
WO2005051318A3 (en) | Compounds, compositions and methods for treatment and prophylaxis of hepatitis c viral infections and associated diseases | |
ATE546154T1 (de) | Anti-angiogenetisches mittel und seine verwendung bei der krebsbehandlung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |