NO20051804L - GHRH analoger - Google Patents
GHRH analogerInfo
- Publication number
- NO20051804L NO20051804L NO20051804A NO20051804A NO20051804L NO 20051804 L NO20051804 L NO 20051804L NO 20051804 A NO20051804 A NO 20051804A NO 20051804 A NO20051804 A NO 20051804A NO 20051804 L NO20051804 L NO 20051804L
- Authority
- NO
- Norway
- Prior art keywords
- ghrh
- relates
- present
- analogs
- human
- Prior art date
Links
- 101710142969 Somatoliberin Proteins 0.000 title abstract 5
- 102100022831 Somatoliberin Human genes 0.000 title 1
- 102000038461 Growth Hormone-Releasing Hormone Human genes 0.000 abstract 4
- 239000000095 Growth Hormone-Releasing Hormone Substances 0.000 abstract 4
- 101000997535 Homo sapiens Growth hormone-releasing hormone receptor Proteins 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 230000007812 deficiency Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000000977 initiatory effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000017854 proteolysis Effects 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/25—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Gastroenterology & Hepatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Toxicology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Reproductive Health (AREA)
- Tropical Medicine & Parasitology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41134002P | 2002-09-18 | 2002-09-18 | |
PCT/CA2003/001418 WO2004027064A2 (fr) | 2002-09-18 | 2003-09-17 | Analogues de ghrh |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20051804L true NO20051804L (no) | 2005-04-13 |
Family
ID=32030666
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20051804A NO20051804L (no) | 2002-09-18 | 2005-04-13 | GHRH analoger |
Country Status (13)
Country | Link |
---|---|
US (2) | US20060128615A1 (fr) |
EP (1) | EP1539959A2 (fr) |
JP (1) | JP2006504694A (fr) |
KR (1) | KR20050071498A (fr) |
CN (1) | CN1688696A (fr) |
BR (1) | BR0314619A (fr) |
CA (1) | CA2496687A1 (fr) |
MX (1) | MXPA05002991A (fr) |
NO (1) | NO20051804L (fr) |
NZ (1) | NZ539218A (fr) |
RU (1) | RU2005111253A (fr) |
WO (1) | WO2004027064A2 (fr) |
ZA (1) | ZA200502221B (fr) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5649825B2 (ja) | 2007-01-31 | 2015-01-07 | デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド | 安定化させたp53ペプチドおよびその使用法 |
KR101525754B1 (ko) | 2007-03-28 | 2015-06-09 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 스티칭된 폴리펩티드 |
KR20090130044A (ko) * | 2007-04-04 | 2009-12-17 | 쎄러테크놀로지스 인코포레이티드 | Ghrh 분자의 약제 제형 |
US20090088380A1 (en) * | 2007-07-12 | 2009-04-02 | Pierrette Gaudreau | Ghrh analogs and therapeutic uses thereof |
US20100267636A1 (en) * | 2009-04-20 | 2010-10-21 | Theratechnologies Inc. | Use of cytochrome p450-metabolized drugs and grf molecules in combination therapy |
US20100267635A1 (en) * | 2009-04-20 | 2010-10-21 | Theratechonolgies Inc. | Use of protease inhibitors and grf molecules in combination therapy |
WO2011153491A2 (fr) | 2010-06-03 | 2011-12-08 | University Of Miami | Agonistes de l'hormone de libération de l'hormone de croissance en tant qu'effecteurs de la survie et de la prolifération d'îlots pancréatiques |
CN108570097A (zh) | 2010-08-13 | 2018-09-25 | 爱勒让治疗公司 | 拟肽大环化合物 |
EP2616095A4 (fr) * | 2010-09-16 | 2014-03-19 | Univ Miami | Accélération de la cicatrisation des plaies par l'hormone de libération de l'hormone de croissance et ses agonistes |
CN103547591A (zh) | 2011-04-21 | 2014-01-29 | 瑟瑞技术公司 | 生长激素释放因子(grf)类似物及其用途 |
MX358886B (es) | 2011-10-18 | 2018-08-31 | Aileron Therapeutics Inc | Macrociclos peptidomimeticos. |
US9079974B2 (en) | 2011-12-21 | 2015-07-14 | The University Of Miami | GH-RH analogs with potent agonistic effects |
SG11201404648PA (en) | 2012-02-15 | 2014-09-26 | Aileron Therapeutics Inc | Peptidomimetic macrocycles |
US8987414B2 (en) | 2012-02-15 | 2015-03-24 | Aileron Therapeutics, Inc. | Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles |
WO2013190520A2 (fr) | 2012-06-22 | 2013-12-27 | The General Hospital Corporation | Agents de libération de gh dans le traitement d'une sténose vasculaire et d'états associés |
EP2914256B1 (fr) | 2012-11-01 | 2019-07-31 | Aileron Therapeutics, Inc. | Acides aminés disubstitués et procédés de préparation et d'utilisation de ceux-ci |
US9855312B2 (en) | 2012-12-21 | 2018-01-02 | University Of Miami | GHRH agonists for the treatment of ischemic disorders |
US9393271B2 (en) | 2012-12-21 | 2016-07-19 | University Of Miami | GHRH agonists for islet cell transplantation and function and the treatment of diabetes |
WO2015100423A2 (fr) * | 2013-12-24 | 2015-07-02 | University Of Miami | Méthodes de traitement de cancer au moyen d'agonistes de ghrh |
CN105198966B (zh) * | 2014-06-26 | 2019-06-21 | 中国人民解放军军事医学科学院毒物药物研究所 | GnRH类似物-细胞毒分子缀合物、其制备方法及用途 |
JP2017533889A (ja) | 2014-09-24 | 2017-11-16 | エルロン・セラピューティクス・インコーポレイテッドAileron Therapeutics,Inc. | ペプチド模倣大環状分子およびその使用 |
CN104558150B (zh) * | 2014-11-04 | 2017-12-15 | 广东药学院 | 一类生长激素释放激素类似肽及其在制备治疗不孕不育药物中的应用 |
EP3294318A4 (fr) | 2015-03-20 | 2019-04-03 | Aileron Therapeutics, Inc. | Macrocycles peptidomimétiques et leurs utilisations |
HUE052802T2 (hu) | 2016-04-19 | 2021-05-28 | Griffon Pharmaceuticals Int Sa | Pegilezett bioaktív peptidek és alkalmazásaik |
CN111407884B (zh) * | 2019-06-24 | 2021-12-07 | 浙江大学 | 促生长激素释放激素激动剂ghrh-a在制备抗衰老药物中的用途 |
CN111533800B (zh) * | 2020-03-18 | 2021-08-31 | 浙江湖州纳福生物医药有限公司 | 新型生长激素释放激素类似肽改构和二聚体化制备及其应用 |
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-
2003
- 2003-09-17 CN CNA038222914A patent/CN1688696A/zh active Pending
- 2003-09-17 MX MXPA05002991A patent/MXPA05002991A/es unknown
- 2003-09-17 BR BR0314619-7A patent/BR0314619A/pt not_active IP Right Cessation
- 2003-09-17 CA CA002496687A patent/CA2496687A1/fr not_active Abandoned
- 2003-09-17 RU RU2005111253/13A patent/RU2005111253A/ru not_active Application Discontinuation
- 2003-09-17 US US10/527,598 patent/US20060128615A1/en not_active Abandoned
- 2003-09-17 WO PCT/CA2003/001418 patent/WO2004027064A2/fr active Application Filing
- 2003-09-17 NZ NZ539218A patent/NZ539218A/en unknown
- 2003-09-17 KR KR1020057004781A patent/KR20050071498A/ko not_active Application Discontinuation
- 2003-09-17 JP JP2004536729A patent/JP2006504694A/ja active Pending
- 2003-09-17 EP EP03750194A patent/EP1539959A2/fr not_active Withdrawn
-
2005
- 2005-03-16 ZA ZA200502221A patent/ZA200502221B/en unknown
- 2005-04-13 NO NO20051804A patent/NO20051804L/no not_active Application Discontinuation
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2007
- 2007-06-01 US US11/809,596 patent/US20090023646A1/en not_active Abandoned
Also Published As
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US20060128615A1 (en) | 2006-06-15 |
NZ539218A (en) | 2008-03-28 |
ZA200502221B (en) | 2006-08-30 |
JP2006504694A (ja) | 2006-02-09 |
CN1688696A (zh) | 2005-10-26 |
WO2004027064A2 (fr) | 2004-04-01 |
US20090023646A1 (en) | 2009-01-22 |
BR0314619A (pt) | 2005-08-02 |
MXPA05002991A (es) | 2005-10-05 |
WO2004027064A3 (fr) | 2004-11-18 |
EP1539959A2 (fr) | 2005-06-15 |
CA2496687A1 (fr) | 2004-04-01 |
KR20050071498A (ko) | 2005-07-07 |
AU2003269631A1 (en) | 2004-04-08 |
RU2005111253A (ru) | 2005-11-20 |
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