NO20030635L - Rensing av HBV-antigener for anvendelse i vaksiner - Google Patents

Rensing av HBV-antigener for anvendelse i vaksiner

Info

Publication number
NO20030635L
NO20030635L NO20030635A NO20030635A NO20030635L NO 20030635 L NO20030635 L NO 20030635L NO 20030635 A NO20030635 A NO 20030635A NO 20030635 A NO20030635 A NO 20030635A NO 20030635 L NO20030635 L NO 20030635L
Authority
NO
Norway
Prior art keywords
vaccines
purification
hbv antigens
hbv
antigens
Prior art date
Application number
NO20030635A
Other languages
English (en)
Norwegian (no)
Other versions
NO20030635D0 (no
Inventor
Koen De Heyder
Peter Schu
Michelle Serantoni
Omer Van Opstal
Original Assignee
Glaxosmithkline Biolog Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0019728.5A external-priority patent/GB0019728D0/en
Priority claimed from GB0101334A external-priority patent/GB0101334D0/en
Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa
Publication of NO20030635D0 publication Critical patent/NO20030635D0/no
Publication of NO20030635L publication Critical patent/NO20030635L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/01—DNA viruses
    • C07K14/02—Hepadnaviridae, e.g. hepatitis B virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0016—Combination vaccines based on diphtheria-tetanus-pertussis
    • A61K39/0018—Combination vaccines based on acellular diphtheria-tetanus-pertussis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32611—Poliovirus
    • C12N2770/32634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
NO20030635A 2000-08-10 2003-02-07 Rensing av HBV-antigener for anvendelse i vaksiner NO20030635L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0019728.5A GB0019728D0 (en) 2000-08-10 2000-08-10 Novel treatment
GB0101334A GB0101334D0 (en) 2001-01-18 2001-01-18 Novel compounds
PCT/EP2001/009100 WO2002012287A1 (en) 2000-08-10 2001-08-07 Purification of hbv antigens for use in vaccines

Publications (2)

Publication Number Publication Date
NO20030635D0 NO20030635D0 (no) 2003-02-07
NO20030635L true NO20030635L (no) 2003-04-01

Family

ID=26244821

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20030635A NO20030635L (no) 2000-08-10 2003-02-07 Rensing av HBV-antigener for anvendelse i vaksiner

Country Status (36)

Country Link
US (3) US20030235590A1 (cs)
EP (2) EP1307473B1 (cs)
JP (2) JP2004505992A (cs)
KR (1) KR100804922B1 (cs)
CN (1) CN1468256B (cs)
AP (1) AP2003002734A0 (cs)
AR (1) AR030325A1 (cs)
AT (2) ATE412665T1 (cs)
AU (2) AU2001282073B2 (cs)
BG (1) BG66038B1 (cs)
BR (1) BRPI0113155C1 (cs)
CA (2) CA2427475C (cs)
CY (2) CY1106310T1 (cs)
CZ (1) CZ303217B6 (cs)
DE (2) DE60116107T2 (cs)
DK (2) DK1666487T3 (cs)
DZ (1) DZ3470A1 (cs)
EA (1) EA006433B1 (cs)
EG (1) EG25829A (cs)
ES (2) ES2254464T3 (cs)
HK (1) HK1056884A1 (cs)
HU (1) HU228932B1 (cs)
IL (2) IL154301A0 (cs)
MX (1) MXPA03001235A (cs)
MY (1) MY128999A (cs)
NO (1) NO20030635L (cs)
NZ (1) NZ524012A (cs)
OA (1) OA12361A (cs)
PE (1) PE20020287A1 (cs)
PL (1) PL204736B1 (cs)
PT (1) PT1666487E (cs)
SI (2) SI1307473T1 (cs)
SK (2) SK288079B6 (cs)
UA (1) UA79735C2 (cs)
UY (1) UY26882A1 (cs)
WO (1) WO2002012287A1 (cs)

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CN106222129A (zh) * 2016-07-29 2016-12-14 广东东阳光药业有限公司 一种提高抗体纯度的细胞培养基和培养方法
GEP20227386B (en) 2017-07-18 2022-06-10 Serum Institute Of India Pvt Ltd Immunogenic composition having improved stability, enhanced immunogenicity and reduced reactogenicity and process for preparation thereof
GB201721069D0 (en) 2017-12-15 2018-01-31 Glaxosmithkline Biologicals Sa Hepatitis B Immunisation regimen and compositions
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Also Published As

Publication number Publication date
SK288079B6 (sk) 2013-06-03
HUP0302951A2 (hu) 2003-12-29
BG66038B1 (bg) 2010-11-30
EG25829A (en) 2012-09-02
PL204736B1 (pl) 2010-02-26
EP1666487B1 (en) 2008-10-29
CA2427475C (en) 2011-07-05
US8624004B2 (en) 2014-01-07
UY26882A1 (es) 2002-03-22
PT1666487E (pt) 2008-12-26
HU228932B1 (en) 2013-06-28
SI1307473T1 (sl) 2006-04-30
SK1692003A3 (en) 2003-08-05
JP2012255015A (ja) 2012-12-27
AU8207301A (en) 2002-02-18
EP1307473A1 (en) 2003-05-07
HK1056884A1 (en) 2004-03-05
JP5559847B2 (ja) 2014-07-23
SK288069B6 (sk) 2013-05-03
PL362322A1 (en) 2004-10-18
HUP0302951A3 (en) 2004-10-28
BR0113155A (pt) 2003-07-08
AP2003002734A0 (en) 2003-03-31
NO20030635D0 (no) 2003-02-07
CZ2003385A3 (cs) 2003-06-18
EA006433B1 (ru) 2005-12-29
MY128999A (en) 2007-03-30
KR100804922B1 (ko) 2008-02-20
ES2314555T3 (es) 2009-03-16
US20090123496A1 (en) 2009-05-14
SI1666487T1 (sl) 2009-02-28
BRPI0113155B1 (pt) 2018-11-21
CN1468256B (zh) 2010-10-27
DK1666487T3 (da) 2009-01-12
ATE412665T1 (de) 2008-11-15
CN1468256A (zh) 2004-01-14
DE60136400D1 (de) 2008-12-11
WO2002012287A1 (en) 2002-02-14
MXPA03001235A (es) 2004-07-16
CA2427475A1 (en) 2002-02-11
BRPI0113155C1 (pt) 2021-05-25
DE60116107D1 (de) 2006-01-26
KR20030029127A (ko) 2003-04-11
EP1307473B1 (en) 2005-12-21
BG107545A (bg) 2004-01-30
EP1666487A1 (en) 2006-06-07
DE60116107T2 (de) 2006-08-03
NZ524012A (en) 2004-02-27
AU2001282073B2 (en) 2005-01-20
JP2004505992A (ja) 2004-02-26
OA12361A (en) 2004-04-13
US20060159705A1 (en) 2006-07-20
UA79735C2 (uk) 2007-07-25
IL154301A0 (en) 2003-09-17
PE20020287A1 (es) 2002-06-20
DZ3470A1 (fr) 2002-02-14
ATE313558T1 (de) 2006-01-15
BRPI0113155B8 (pt) 2019-08-13
CZ303217B6 (cs) 2012-05-30
IL154301A (en) 2009-11-18
CY1106310T1 (el) 2011-10-12
CA2740282A1 (en) 2002-02-11
US20030235590A1 (en) 2003-12-25
CY1108789T1 (el) 2014-04-09
ES2254464T3 (es) 2006-06-16
EA200300129A1 (ru) 2003-10-30
DK1307473T3 (da) 2006-05-01
AR030325A1 (es) 2003-08-20

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