DE69928763D1 - Adjuvanzien zur Verwendung in Impfstoffen - Google Patents
Adjuvanzien zur Verwendung in ImpfstoffenInfo
- Publication number
- DE69928763D1 DE69928763D1 DE69928763T DE69928763T DE69928763D1 DE 69928763 D1 DE69928763 D1 DE 69928763D1 DE 69928763 T DE69928763 T DE 69928763T DE 69928763 T DE69928763 T DE 69928763T DE 69928763 D1 DE69928763 D1 DE 69928763D1
- Authority
- DE
- Germany
- Prior art keywords
- vaccines
- adjuvants
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0241—Mollicutes, e.g. Mycoplasma, Erysipelothrix
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/099—Bordetella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/825—Bacterial vaccine for porcine species, e.g. swine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11770599P | 1999-01-29 | 1999-01-29 | |
US117705P | 1999-01-29 | ||
US12176099P | 1999-02-26 | 1999-02-26 | |
US121760P | 1999-02-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69928763D1 true DE69928763D1 (de) | 2006-01-12 |
DE69928763T2 DE69928763T2 (de) | 2006-06-29 |
Family
ID=26815550
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69928763T Expired - Lifetime DE69928763T2 (de) | 1999-01-29 | 1999-12-23 | Adjuvanzien zur Verwendung in Impfstoffen |
Country Status (17)
Country | Link |
---|---|
US (6) | US6572861B1 (de) |
EP (2) | EP1616573B1 (de) |
JP (3) | JP2000219636A (de) |
CN (2) | CN1126568C (de) |
AR (2) | AR035474A1 (de) |
AT (2) | ATE311900T1 (de) |
AU (2) | AU769539B2 (de) |
BR (2) | BRPI0017566B1 (de) |
CA (2) | CA2455134C (de) |
CY (2) | CY1105684T1 (de) |
DE (1) | DE69928763T2 (de) |
DK (2) | DK1616573T3 (de) |
ES (2) | ES2374628T3 (de) |
HK (2) | HK1030166A1 (de) |
NZ (2) | NZ502341A (de) |
PT (1) | PT1616573E (de) |
TW (1) | TW585777B (de) |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU769539B2 (en) * | 1999-01-29 | 2004-01-29 | Zoetis Services Llc | Adjuvants for use in vaccines |
US6676958B2 (en) * | 2001-06-19 | 2004-01-13 | Advanced Bioadjuvants, Llc | Adjuvant composition for mucosal and injection delivered vaccines |
US7279163B1 (en) * | 2002-03-21 | 2007-10-09 | The United States Of America, As Represented By The Secretary Of Agriculture | Water-in-oil emulsion vaccines |
KR20050062542A (ko) * | 2002-08-26 | 2005-06-23 | 화이자 프로덕츠 인코포레이티드 | 소의 호흡기 및 생식기계 감염에 대한 백신 |
PL378001A1 (pl) * | 2003-01-29 | 2006-02-20 | Pfizer Products Inc. | Szczepionki przeciw Bordetella bronchiseptica dla psów |
ES2398235T3 (es) * | 2003-04-04 | 2013-03-14 | Pah Usa 15 Llc | Emulsiones de aceite en agua microfluidizadas y composiciones de vacunas |
US8637047B2 (en) * | 2003-10-30 | 2014-01-28 | Boehringer Ingelheim Vetmedica, Inc. | Erysipelothrix rhusiopathiae-haemophilus parasuis vaccine and methods of using the same |
CN1323718C (zh) * | 2004-03-15 | 2007-07-04 | 中国农业科学院兰州兽医研究所 | 一种利用植物油佐剂制备动物病毒性、细菌性疫苗的方法 |
FR2878746B1 (fr) * | 2004-12-02 | 2007-02-23 | Vetoquinol Sa Sa | Nouvelle composition pharmaceutique utilisable dans le domaine des vaccins |
CN1320924C (zh) * | 2005-01-07 | 2007-06-13 | 邢为藩 | 一种自乳化疫苗佐剂及其制备方法 |
US20090317421A1 (en) | 2006-01-18 | 2009-12-24 | Dominique Missiakas | Compositions and methods related to staphylococcal bacterium proteins |
ES2657392T3 (es) | 2006-09-26 | 2018-03-05 | Infectious Disease Research Institute | Composición de vacuna que contiene un adyuvante sintético |
US20090181078A1 (en) * | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
NZ576563A (en) * | 2006-11-03 | 2012-09-28 | Alphavax Inc | Alphavirus and alphavirus replicon particle formulations and methods |
US20090017064A1 (en) * | 2007-07-10 | 2009-01-15 | Wyeth | Methods and Compositions for Immunizing Pigs Against Porcine Circovirus |
EP2197497B1 (de) | 2007-09-27 | 2016-06-01 | ImmunoVaccine Technologies Inc. | Verwendung von liposomen in einem träger mit einer kontinuierlichen hydrophoben phase zur abgabe von polynucleotiden in vivo |
US20100209452A1 (en) * | 2007-10-03 | 2010-08-19 | Immunovaccine Technologies, Inc | Compositions comprising an antigen, an amphipathic compound and a hydrophobic carrier, and uses thereof |
WO2009059328A2 (en) * | 2007-11-02 | 2009-05-07 | The Johns Hopkins University | Multi- component l2 vaccine for prevention of human papillomavirus infection |
CN101428145B (zh) * | 2007-11-05 | 2013-01-02 | 北京生泰尔生物科技有限公司 | 新型疫苗佐剂 |
EP2296696B1 (de) | 2008-06-05 | 2014-08-27 | ImmunoVaccine Technologies Inc. | Zusammensetzungen mit liposomen, einem antigen, einem polynucleotid und einem träger mit einer kontinuierlichen phase einer hydrophoben substanz |
JP5659332B2 (ja) | 2008-06-27 | 2015-01-28 | ゾエティス・エルエルシー | 新規なアジュバント組成物 |
CN102333540B (zh) | 2008-10-06 | 2015-04-22 | 芝加哥大学 | 与细菌eap、emp和/或adsa蛋白相关的组合物和方法 |
BRPI1010307B1 (pt) | 2009-04-03 | 2021-07-27 | University Of Chicago | Polipeptídeos variantes de proteína a (spa), composição imunogênica compreendendo os mesmos, vacina, método de produção da referida vacina, bem como uso dos referidos polipeptídeos |
PT2437753T (pt) | 2009-06-05 | 2016-11-23 | Infectious Disease Res Inst | Adjuvantes lipídicos de glucopiranosilo sintéticos e composições de vacina contendo os mesmos |
US9241987B2 (en) | 2009-11-20 | 2016-01-26 | The University Of Chicago | Methods and compositions related to immunogenic fibrils |
US9849174B2 (en) | 2009-11-20 | 2017-12-26 | The Board Of Regents Of The University Of Texas System | Methods and compositions related to immunogenic fibrils |
US10080799B2 (en) | 2010-02-12 | 2018-09-25 | Arizona Board Of Regents On Behalf Of Arizona State University | Methods and compositions related to glycoprotein-immunoglobulin fusions |
CA2792369A1 (en) | 2010-03-11 | 2011-09-15 | Immune Design Corp. | Vaccines for influenza |
JP2013523818A (ja) | 2010-04-05 | 2013-06-17 | ザ・ユニバーシティー・オブ・シカゴ | 免疫反応のエンハンサーとしてのプロテインA(SpA)抗体に関連する組成物および方法 |
US9050319B2 (en) | 2010-04-30 | 2015-06-09 | Telormedix, Sa | Phospholipid drug analogs |
WO2011134669A1 (en) | 2010-04-30 | 2011-11-03 | Telormedix Sa | Methods for inducing an immune response |
NZ603155A (en) | 2010-04-30 | 2014-06-27 | Telormedix Sa | Phospholipid drug analogs |
CN103037885B (zh) | 2010-07-02 | 2015-08-26 | 芝加哥大学 | 与蛋白A(SpA)变体相关的组合物和方法 |
WO2012034067A1 (en) | 2010-09-09 | 2012-03-15 | The University Of Chicago | Methods and compositions involving protective staphylococcal antigens |
EP2623118A4 (de) * | 2010-09-28 | 2014-05-07 | Kyoritsu Seiyaku Corp | Schleimhautadjuvantienzusammensetzung |
MX350795B (es) | 2011-04-08 | 2017-09-19 | Inmune Design Corp | Composiciones inmunogenicas y metodos para utilizar las composiciones para inducir respuestas inmunes humorales y celulares. |
US20120288515A1 (en) | 2011-04-27 | 2012-11-15 | Immune Design Corp. | Synthetic long peptide (slp)-based vaccines |
US8945588B2 (en) | 2011-05-06 | 2015-02-03 | The University Of Chicago | Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides |
CN103998058B (zh) | 2011-10-06 | 2021-11-05 | 免疫疫苗技术有限公司 | 包括激活或增加tlr2活性的佐剂的脂质体组合物及其应用 |
GB201205237D0 (en) | 2012-03-26 | 2012-05-09 | Univ Edinburgh | Adjuvant |
US9968668B2 (en) | 2012-04-26 | 2018-05-15 | The University Of Chicago | Staphylococcal coagulase antigens and methods of their use |
LT2850431T (lt) | 2012-05-16 | 2018-06-25 | Immune Design Corp. | Vakcinos, skirtos hsv-2 |
HUE059179T2 (hu) | 2012-09-10 | 2022-10-28 | Galenbio Inc | Vízimadárban Mycoplasma-fertõzés megelõzésére szolgáló oltóanyag |
CA2881863A1 (en) | 2012-10-01 | 2014-04-10 | Telormedix Sa | Phospholipid drug analogs |
JP6426706B2 (ja) | 2013-04-18 | 2018-11-21 | イミューン デザイン コーポレイション | がん処置で使用するためのgla単剤療法 |
US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
PL3166634T3 (pl) | 2014-07-11 | 2021-12-27 | Zoetis Services Llc | Nowe kompozycje szczepionek przeciwko wirusowi biegunki epidemicznej świń |
WO2016138421A1 (en) | 2015-02-27 | 2016-09-01 | Iowa State University Research Foundation, Inc. | Porcine epidemic diarrhea virus strains and immunogenic compositions therefrom |
CA3010977A1 (en) | 2016-01-11 | 2017-07-20 | Zoetis Services Llc | Novel cross protective vaccine compositions for porcine epidemic diarrhea virus |
EP3432922B1 (de) | 2016-03-21 | 2020-02-19 | South Dakota Board of Regents | Orf-virusbasierte plattform für die verabreichung von impfstoffen |
US11246924B2 (en) | 2016-04-01 | 2022-02-15 | Duke University | Alpha-helical peptide nanofibers as a self-adjuvanting vaccine platform |
US10662226B2 (en) | 2016-10-28 | 2020-05-26 | The Regents of the University of Caiifomia | Synthetic beta-amyloid peptides capable of forming stable antigenic oligomers |
GB201703529D0 (en) | 2017-03-06 | 2017-04-19 | Cambridge Entpr Ltd | Vaccine composition |
CN107027749B (zh) * | 2017-05-24 | 2021-04-09 | 浙江工业大学 | 一种复合乳化剂及其在复配毒死蜱农药中的应用 |
ES2705378A1 (es) * | 2017-09-22 | 2019-03-22 | Decco Worldwide Post Harvest Holdings B V | Metodo para el tratamiento y control de fisiopatias de postcosecha de frutas mediante recubrimientos comestibles. |
WO2019183500A1 (en) | 2018-03-23 | 2019-09-26 | Hung Chiung Yu | Coccidioides antigens and methods of their use |
WO2020044267A1 (en) | 2018-08-29 | 2020-03-05 | Centre Hospitalier Universitaire Vaudois | Ebola vaccine compositions and methods of using same |
US11208167B2 (en) | 2018-11-15 | 2021-12-28 | Kuat Innovations Llc | Bicycle rack with actuated arm |
CN114315985A (zh) | 2020-09-29 | 2022-04-12 | 硕腾服务有限责任公司 | 减毒猪流行性腹泻病毒 |
CN115216451A (zh) | 2021-04-16 | 2022-10-21 | 硕腾服务有限责任公司 | 伪狂犬病病毒疫苗 |
TW202327646A (zh) | 2021-10-15 | 2023-07-16 | 美商輝瑞大藥廠 | Rna分子 |
CN113907044A (zh) * | 2021-11-09 | 2022-01-11 | 福建省连江县刘氏兔业养殖场 | 一种抗病猪品系的培育方法及其应用 |
WO2023111907A1 (en) | 2021-12-17 | 2023-06-22 | Pfizer Inc. | Polynucleotide compositions and uses thereof |
WO2023144779A1 (en) | 2022-01-28 | 2023-08-03 | Pfizer Inc. | Coronavirus antigen variants |
TW202424187A (zh) | 2022-10-27 | 2024-06-16 | 美商輝瑞大藥廠 | Rna分子 |
WO2024089634A1 (en) | 2022-10-27 | 2024-05-02 | Pfizer Inc. | Immunogenic compositions against influenza and rsv |
WO2024127181A1 (en) | 2022-12-11 | 2024-06-20 | Pfizer Inc. | Immunogenic compositions against influenza and rsv |
CN118267462A (zh) | 2022-12-29 | 2024-07-02 | 硕腾服务有限责任公司 | 接种猪以抗伪狂犬病病毒的方法 |
WO2024154052A1 (en) | 2023-01-16 | 2024-07-25 | Pfizer Inc. | Immunogenic compositions and methods of inducing an immune response against varicella zoster virus |
Family Cites Families (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4075321A (en) * | 1973-05-04 | 1978-02-21 | Agence Nationale De Valorisation De La Recherche (Anvar) | Vaccines, the process for preparing the same and the applications thereof |
AT350181B (de) * | 1977-05-04 | 1979-05-10 | Schuller Walter Dr | Verfahren zur herstellung einer mischvaccine |
US4137115A (en) * | 1977-11-07 | 1979-01-30 | Patrick Lambert | Joining structure |
US4237115A (en) * | 1977-11-23 | 1980-12-02 | Bactex, Inc. | Method of immunization against enterotoxogenic infection by Escherichia coli |
US4261925A (en) | 1978-04-05 | 1981-04-14 | The Dow Chemical Company | Surfactants |
US4504275A (en) | 1983-03-24 | 1985-03-12 | Imperial Chemical Industries Plc | Emulsifying agents |
US4606918A (en) | 1983-08-22 | 1986-08-19 | Syntex (U.S.A.) Inc. | Polyoxypropylene-polyoxyethylene block polymer based adjuvants |
US4933179A (en) | 1983-08-22 | 1990-06-12 | Syntex (U.S.A.) Inc. | Feline leukemia virus antigen vaccines |
US5338748A (en) | 1985-01-18 | 1994-08-16 | Cetylite Industries, Inc. | Sterilant composition |
US5424323A (en) * | 1985-01-18 | 1995-06-13 | Cetylite Industries, Inc. | Sterilant composition |
DE3517805A1 (de) * | 1985-05-17 | 1986-11-20 | Bayer Ag, 5090 Leverkusen | Impfstoff zur immunisierung von schweinen gegen rhinitis atrophicans (schnueffelkrankheit) |
US4803070A (en) * | 1986-04-15 | 1989-02-07 | Ribi Immunochem Research Inc. | Immunological emulsion adjuvants for polysaccharide vaccines |
US4789544A (en) * | 1986-05-23 | 1988-12-06 | Midcon Labs. Inc. | Co-vaccination using non-O-carbohydrate side-chain gram-negative bacteria preparation |
US5019388A (en) * | 1986-10-14 | 1991-05-28 | Norden Laboratories Inc. | Bordetella bronchiseptica vaccine |
US4888169A (en) | 1986-10-14 | 1989-12-19 | Norden Laboratories, Inc. | Bordetella Bronchiseptica vaccine |
US5084269A (en) | 1986-11-06 | 1992-01-28 | Kullenberg Fred W | Adjuvant for dose treatment with antigens |
US5209929A (en) * | 1987-03-19 | 1993-05-11 | Washington State University Research Foundation | Immunization against Babesiosis using purified merozoite surface antigens of Basesia bigemina |
US5376369A (en) | 1987-11-03 | 1994-12-27 | Syntex (U.S.A.) Inc. | Vaccine adjuvant |
US5069901A (en) * | 1988-02-03 | 1991-12-03 | Jones Elaine V | Preparation of a recombinant subunit vaccine against pseudorabies infection |
GB8822857D0 (en) * | 1988-09-29 | 1988-11-02 | Patralan Ltd | Pharmaceutical formulations |
FR2649012B1 (fr) * | 1989-07-03 | 1991-10-25 | Seppic Sa | Emulsions multiphasiques injectables |
US5223253A (en) * | 1989-09-28 | 1993-06-29 | American Home Products Corporation | Bovine vaccine compositions and method for preventing trichomonas infections using same |
JP3035712B2 (ja) * | 1990-02-12 | 2000-04-24 | スミスクライン ビーチャム バイオロジカルズ(エス ア) | 新規なワクチンおよびそのための方法 |
US5578308A (en) | 1990-02-12 | 1996-11-26 | Capiau; Carine | Glutaraldehyde and formalin detoxified bordetella toxin vaccine |
WO1991018627A1 (en) * | 1990-05-29 | 1991-12-12 | Smithkline Beecham Corporation | Swine pneumonia vaccine and method for the preparation thereof |
WO1991019419A1 (en) | 1990-06-13 | 1991-12-26 | Smithkline Beecham Corporation | Pasteurella multocida toxoid vaccines |
US5695769A (en) | 1990-06-13 | 1997-12-09 | Pfizer Inc. | Pasteurella multocida toxoid vaccines |
US5242686A (en) * | 1990-11-07 | 1993-09-07 | American Home Products Corporation | Feline vaccine compositions and method for preventing chlamydia infections or diseases using the same |
DK0669971T3 (da) | 1991-11-15 | 2003-04-22 | Pfizer | Fremgangsmåde til fremstilling af Gram-negative bakterielle vacciner |
US5338543A (en) * | 1992-02-27 | 1994-08-16 | Ambico, Inc. | Thimerosal inactivated mycoplasma hyopneumoniae vaccine |
US5422277A (en) * | 1992-03-27 | 1995-06-06 | Ortho Diagnostic Systems Inc. | Cell fixative composition and method of staining cells without destroying the cell surface |
DE4222153C2 (de) | 1992-07-06 | 1998-12-03 | Peter Siegfried | Verfahren zur Entölung von Rohlecithin |
DE69419966T2 (de) | 1993-05-17 | 2000-01-20 | Akzo Nobel N.V., Arnheim/Arnhem | Impstoff gegen Streptococcus suis-Infektion |
AU5543294A (en) * | 1993-10-29 | 1995-05-22 | Pharmos Corp. | Submicron emulsions as vaccine adjuvants |
AU679845B2 (en) * | 1994-02-18 | 1997-07-10 | Solidose L.L.C. | Inoculation of animals with dried, pelleted biological materials |
DK53595A (da) * | 1994-05-13 | 1995-11-14 | Iberica Cyanamid | Rekombinante PRRSV-proteiner, diagnostiske kits og vaccine indeholdende sådanne rekombinante PRRSV-proteiner |
DK0773030T3 (da) * | 1994-06-10 | 2003-12-22 | Chemo Sero Therapeut Res Inst | Fremgangsmåde til oprensning af nekrotoksin produceret af Bordetella |
US5538733A (en) * | 1994-07-07 | 1996-07-23 | Willmar Poultry Company, Inc. | Method of priming an immune response in a one-day old animal |
US5625038A (en) * | 1994-07-27 | 1997-04-29 | Henderson; Louise M. | Monoclonal antibodies specific for Erysipelothrix rhusiopathiae |
US5603951A (en) | 1994-11-09 | 1997-02-18 | Hanmi Pharm. Ind. Co., Ltd. | Cyclosporin-containing soft capsule compositions |
GB9620795D0 (en) | 1996-10-05 | 1996-11-20 | Smithkline Beecham Plc | Vaccines |
US5877298A (en) * | 1995-05-04 | 1999-03-02 | Connaught Lab | Acellular pertussis vaccines and methods of preparing thereof |
US5690942A (en) * | 1995-06-02 | 1997-11-25 | American Home Products Corporation | Adjuvants for viral vaccines |
US5718904A (en) * | 1995-06-02 | 1998-02-17 | American Home Products Corporation | Adjuvants for viral vaccines |
TW410158B (en) * | 1995-11-30 | 2000-11-01 | Chemo Sero Therapeut Res Inst | Oil adjuvant vaccine and method for preparing same |
PT835930E (pt) | 1996-10-09 | 2001-06-29 | Akzo Nobel Nv | Estirpes europeias de vacina do virus do sindroma reprodutivo e respiratorio porcino (prrsv) |
ZA982870B (en) * | 1997-04-10 | 1998-10-09 | Akzo Nobel Nv | Live attenuated bacteria of the species actinobacillus pleuropneumoniae |
US6517843B1 (en) * | 1999-08-31 | 2003-02-11 | Merial | Reduction of porcine circovirus-2 viral load with inactivated PCV-2 |
AU769539B2 (en) * | 1999-01-29 | 2004-01-29 | Zoetis Services Llc | Adjuvants for use in vaccines |
US6585981B1 (en) | 2000-07-27 | 2003-07-01 | Regents Of The University Of Minnesota | Temperature-sensitive live vaccine for Mycoplasma hyopneumoniae |
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1999
- 1999-12-21 AU AU65372/99A patent/AU769539B2/en not_active Expired
- 1999-12-23 DE DE69928763T patent/DE69928763T2/de not_active Expired - Lifetime
- 1999-12-23 PT PT05023118T patent/PT1616573E/pt unknown
- 1999-12-23 AT AT99310514T patent/ATE311900T1/de active
- 1999-12-23 EP EP05023118A patent/EP1616573B1/de not_active Expired - Lifetime
- 1999-12-23 AT AT05023118T patent/ATE533504T1/de active
- 1999-12-23 ES ES05023118T patent/ES2374628T3/es not_active Expired - Lifetime
- 1999-12-23 EP EP99310514A patent/EP1023904B1/de not_active Expired - Lifetime
- 1999-12-23 DK DK05023118.2T patent/DK1616573T3/da active
- 1999-12-23 DK DK99310514T patent/DK1023904T3/da active
- 1999-12-23 ES ES99310514T patent/ES2251164T3/es not_active Expired - Lifetime
- 1999-12-28 TW TW088123144A patent/TW585777B/zh not_active IP Right Cessation
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2000
- 2000-01-14 NZ NZ502341A patent/NZ502341A/en not_active IP Right Cessation
- 2000-01-17 AR ARP000100201A patent/AR035474A1/es active IP Right Grant
- 2000-01-19 BR BRPI0017566A patent/BRPI0017566B1/pt active IP Right Grant
- 2000-01-19 BR BRPI0000126A patent/BRPI0000126B8/pt not_active IP Right Cessation
- 2000-01-19 CA CA2455134A patent/CA2455134C/en not_active Expired - Lifetime
- 2000-01-19 CA CA002296244A patent/CA2296244C/en not_active Expired - Lifetime
- 2000-01-24 US US09/489,713 patent/US6572861B1/en not_active Expired - Lifetime
- 2000-01-26 JP JP2000017032A patent/JP2000219636A/ja active Pending
- 2000-01-28 CN CN00101175A patent/CN1126568C/zh not_active Expired - Lifetime
- 2000-01-28 CN CN031306055A patent/CN1449825B/zh not_active Expired - Lifetime
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2001
- 2001-02-21 HK HK01101261A patent/HK1030166A1/xx not_active IP Right Cessation
- 2001-07-27 NZ NZ513202A patent/NZ513202A/xx not_active IP Right Cessation
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2003
- 2003-03-13 US US10/388,947 patent/US6814971B2/en not_active Expired - Lifetime
- 2003-03-13 US US10/389,140 patent/US20030175309A1/en not_active Abandoned
- 2003-03-13 US US10/389,025 patent/US20030175308A1/en not_active Abandoned
- 2003-03-13 US US10/389,139 patent/US6733754B2/en not_active Expired - Lifetime
- 2003-09-03 JP JP2003311701A patent/JP5167469B2/ja not_active Expired - Lifetime
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2004
- 2004-03-11 AU AU2004201021A patent/AU2004201021A1/en not_active Withdrawn
- 2004-04-15 HK HK04102622.8A patent/HK1059739A1/xx unknown
- 2004-09-29 JP JP2004284688A patent/JP4785365B2/ja not_active Expired - Lifetime
- 2004-09-29 US US10/953,979 patent/US7393535B2/en not_active Expired - Lifetime
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2006
- 2006-03-01 CY CY20061100288T patent/CY1105684T1/el unknown
- 2006-09-11 AR ARP060103942A patent/AR055422A2/es not_active Application Discontinuation
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2011
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