NO20030298L - Nye heteroarylderivater og deres anvendelse som farmasöytiske midler - Google Patents

Nye heteroarylderivater og deres anvendelse som farmasöytiske midler

Info

Publication number
NO20030298L
NO20030298L NO20030298A NO20030298A NO20030298L NO 20030298 L NO20030298 L NO 20030298L NO 20030298 A NO20030298 A NO 20030298A NO 20030298 A NO20030298 A NO 20030298A NO 20030298 L NO20030298 L NO 20030298L
Authority
NO
Norway
Prior art keywords
pharmaceutical agents
heteroaryl derivatives
novel heteroaryl
novel
derivatives
Prior art date
Application number
NO20030298A
Other languages
English (en)
Norwegian (no)
Other versions
NO20030298D0 (no
Inventor
Peter Emig
Eckard Guenter
Juergen Schmidt
Bernd Nickel
Bernhard Kutscher
Original Assignee
Zentaris Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentaris Ag filed Critical Zentaris Ag
Publication of NO20030298D0 publication Critical patent/NO20030298D0/no
Publication of NO20030298L publication Critical patent/NO20030298L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20030298A 2000-07-21 2003-01-20 Nye heteroarylderivater og deres anvendelse som farmasöytiske midler NO20030298L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10035928A DE10035928A1 (de) 2000-07-21 2000-07-21 Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
PCT/EP2001/008261 WO2002008192A1 (de) 2000-07-21 2001-07-18 Neue heteroaryl-derivate und deren verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
NO20030298D0 NO20030298D0 (no) 2003-01-20
NO20030298L true NO20030298L (no) 2003-01-20

Family

ID=7649980

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20030298A NO20030298L (no) 2000-07-21 2003-01-20 Nye heteroarylderivater og deres anvendelse som farmasöytiske midler

Country Status (23)

Country Link
US (5) US6890926B2 (enExample)
EP (1) EP1305290A1 (enExample)
JP (1) JP2004504381A (enExample)
KR (1) KR20030022287A (enExample)
CN (1) CN1443171A (enExample)
AR (1) AR033678A1 (enExample)
AU (2) AU2001279757B2 (enExample)
BG (1) BG107508A (enExample)
BR (1) BR0112589A (enExample)
CA (1) CA2353369A1 (enExample)
CZ (1) CZ2003415A3 (enExample)
DE (1) DE10035928A1 (enExample)
HU (1) HUP0300838A2 (enExample)
IL (1) IL153361A0 (enExample)
MX (1) MXPA02012565A (enExample)
NO (1) NO20030298L (enExample)
NZ (1) NZ524154A (enExample)
PL (1) PL358788A1 (enExample)
RU (1) RU2265602C2 (enExample)
SK (1) SK1842003A3 (enExample)
TW (1) TWI228505B (enExample)
WO (1) WO2002008192A1 (enExample)
ZA (1) ZA200210180B (enExample)

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WO2004007470A1 (de) * 2002-07-17 2004-01-22 Zentaris Gmbh Neue anthracen-derivate und deren verwendung als arzneimittel
MXPA05008099A (es) * 2003-01-28 2005-09-21 Aventis Pharma Sa Productos n-aril-heteroaromaticos, composiciones que los contienen y su utilizacion.
AR044586A1 (es) * 2003-06-04 2005-09-21 Aventis Pharma Sa Productos aril - heteroaromaticos, composiciones que los contienen y su utilizacion
FR2855825B1 (fr) * 2003-06-04 2008-08-22 Aventis Pharma Sa Produits aryl-heteroaromatiques, compositions les contenant et utilisation
WO2005068445A2 (en) * 2004-01-08 2005-07-28 Syngenta Participations Ag Pesticidal heterocyclic dihaloallyl compounds
DE102004003428A1 (de) * 2004-01-23 2005-08-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue langwirksame Beta-2-Agonisten, und deren Verwendung als Arzneimittel
FR2871157A1 (fr) * 2004-06-04 2005-12-09 Aventis Pharma Sa Produits biaryl aromatiques, compositions les contenant et utilisation
CN1830964B (zh) * 2005-03-11 2011-06-15 中国科学院上海药物研究所 4-取代苯氨基-3-硝基喹啉类化合物及其制备方法和用途
KR101139413B1 (ko) * 2006-12-07 2012-06-22 차이나 메디컬 유니버시티 항암제로서 새로운 2-아릴-4-퀴놀론의 친수성 유도체
US8835426B2 (en) * 2007-02-26 2014-09-16 Vitae Pharmaceuticals, Inc. Cyclic urea and carbamate inhibitors of 11β-hydroxysteroid dehydrogenase 1
JP5470557B2 (ja) * 2007-07-26 2014-04-16 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の阻害剤の合成
AR069207A1 (es) * 2007-11-07 2010-01-06 Vitae Pharmaceuticals Inc Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1
CA2708303A1 (en) 2007-12-11 2009-06-18 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
TW200934490A (en) * 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
CA2712500A1 (en) * 2008-01-24 2009-07-30 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2714532A1 (en) * 2008-02-11 2009-08-20 Vitae Pharmaceuticals, Inc. 1,3-oxazepan-2-one and 1,3-diazepan-2-one inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
CA2715290A1 (en) * 2008-02-15 2009-08-20 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5538356B2 (ja) * 2008-03-18 2014-07-02 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の阻害剤
EP2300461B1 (en) * 2008-05-01 2013-04-17 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2723039A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134387A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2723032A1 (en) * 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW201016691A (en) 2008-07-25 2010-05-01 Boehringer Ingelheim Int Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2010127237A2 (en) * 2009-04-30 2010-11-04 Boehringer Ingelheim International Gmbh Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
PL2324018T3 (pl) 2008-07-25 2014-02-28 Boehringer Ingelheim Int Cykliczne inhibitory dehydrogenazy 11 beta-hydroksysteroidowej typu 1
WO2010089303A1 (en) 2009-02-04 2010-08-12 Boehringer Ingelheim International Gmbh CYCLIC INHIBITORS OF 11 β-HYDROXYSTEROID DEHYDROGENASE 1
TW201039034A (en) * 2009-04-27 2010-11-01 Chunghwa Picture Tubes Ltd Pixel structure and the method of forming the same
UA109255C2 (ru) 2009-04-30 2015-08-10 Берінгер Інгельхайм Інтернешнл Гмбх Циклические ингибиторы 11бета-гидроксистероиддегидрогеназы 1
US8927539B2 (en) 2009-06-11 2015-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure
EP2448928B1 (en) 2009-07-01 2014-08-13 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2582698B1 (en) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
WO2011161128A1 (en) 2010-06-25 2011-12-29 Boehringer Ingelheim International Gmbh Azaspirohexanones as inhibitors of 11-beta-hsd1 for the treatment of metabolic disorders
CN103179960A (zh) 2010-11-02 2013-06-26 贝林格尔.英格海姆国际有限公司 治疗代谢疾病的药物组合
JP7471818B2 (ja) * 2016-08-18 2024-04-22 ヴィダック ファーマ リミテッド ピペラジン誘導体、医薬組成物、及びその使用方法

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GR79603B (enExample) * 1982-07-24 1984-10-31 Pfizer
FR2538388B1 (fr) 1982-12-24 1985-06-21 Pharmuka Lab Nouveaux derives de naphtalene- ou azanaphtalenecarboxamide, leurs procedes de preparation et leur utilisation comme medicaments
EP0318235A3 (en) * 1987-11-25 1991-05-02 Takeda Chemical Industries, Ltd. Paf antagonist, 1,4-disubstituted piperazine compounds and production thereof
HUT66081A (en) 1990-10-10 1994-09-28 Schering Corp Process for preparing pyridine and pyridine n-oxide derivatives of diaryl methyl piperidines or piperazines and pharmaceutical compositions containing them
CA2165176A1 (en) * 1993-06-18 1995-01-05 Samuel L. Graham Inhibitors of farnesyl-protein transferase
CA2256492C (en) 1996-05-20 2006-04-04 Teijin Limited Diarylalkyl cyclic diamine derivatives as chemokine receptor antagonists
RU2170730C2 (ru) * 1996-05-20 2001-07-20 Дарвин Дискавери Лимитед Хинолиновые карбоксамиды и фармацевтическая композиция на их основе
ATE241600T1 (de) * 1996-06-29 2003-06-15 Samjin Pharm Co Ltd Piperazin-derivate und verfahren zu ihrer herstellung
US5861395A (en) 1996-09-13 1999-01-19 Schering Corporation Compounds useful for inhibition of farnesyl proteins transferase
FR2753706B1 (fr) 1996-09-20 1998-10-30 Nouvelles amines cycliques n-substituees, leur procede de preparation et les compositions pharmaceutiques les renfermant
KR100538152B1 (ko) * 1997-07-07 2005-12-21 코와 가부시키가이샤 디아민 유도체 및 이를 함유하는 의약
DE19743435A1 (de) 1997-10-01 1999-04-08 Merck Patent Gmbh Benzamidinderivate
CA2342251A1 (en) * 1998-08-28 2000-03-09 Scios Inc. Use of piperidines and/or piperazines as inhibitors of p38-alpha kinase
WO2000051614A1 (en) 1999-03-03 2000-09-08 Merck & Co., Inc. Inhibitors of prenyl-protein transferases
DE10035927A1 (de) * 2000-07-21 2002-03-07 Asta Medica Ag Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
US6610274B1 (en) * 2000-12-22 2003-08-26 Wallace J. Gardner Anti-inflammatory composition comprising tetracycline

Also Published As

Publication number Publication date
US6936615B2 (en) 2005-08-30
DE10035928A1 (de) 2002-03-07
US7056912B2 (en) 2006-06-06
US7026310B2 (en) 2006-04-11
CN1443171A (zh) 2003-09-17
US20050176744A1 (en) 2005-08-11
US6890926B2 (en) 2005-05-10
MXPA02012565A (es) 2003-09-22
NZ524154A (en) 2005-02-25
US20040132747A1 (en) 2004-07-08
EP1305290A1 (de) 2003-05-02
US20020103214A1 (en) 2002-08-01
CA2353369A1 (en) 2002-01-21
US20040097530A1 (en) 2004-05-20
AR033678A1 (es) 2004-01-07
AU2001279757B2 (en) 2005-05-26
SK1842003A3 (en) 2004-10-05
CZ2003415A3 (cs) 2004-05-12
NO20030298D0 (no) 2003-01-20
TWI228505B (en) 2005-03-01
RU2265602C2 (ru) 2005-12-10
HUP0300838A2 (hu) 2003-07-28
US20050245523A1 (en) 2005-11-03
KR20030022287A (ko) 2003-03-15
ZA200210180B (en) 2003-02-12
BG107508A (bg) 2003-09-30
BR0112589A (pt) 2003-05-20
PL358788A1 (en) 2004-08-23
WO2002008192A1 (de) 2002-01-31
IL153361A0 (en) 2003-07-06
JP2004504381A (ja) 2004-02-12
AU7975701A (en) 2002-02-05

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