NO20020814D0 - Nye spiroforbindelser - Google Patents
Nye spiroforbindelserInfo
- Publication number
- NO20020814D0 NO20020814D0 NO20020814A NO20020814A NO20020814D0 NO 20020814 D0 NO20020814 D0 NO 20020814D0 NO 20020814 A NO20020814 A NO 20020814A NO 20020814 A NO20020814 A NO 20020814A NO 20020814 D0 NO20020814 D0 NO 20020814D0
- Authority
- NO
- Norway
- Prior art keywords
- spiro compounds
- new spiro
- new
- compounds
- spiro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Neurosurgery (AREA)
- Reproductive Health (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP23357399 | 1999-08-20 | ||
JP2000137692 | 2000-05-10 | ||
PCT/JP2000/005427 WO2001014376A1 (en) | 1999-08-20 | 2000-08-11 | Novel spiro compounds |
Publications (3)
Publication Number | Publication Date |
---|---|
NO20020814D0 true NO20020814D0 (no) | 2002-02-19 |
NO20020814L NO20020814L (no) | 2002-04-15 |
NO323514B1 NO323514B1 (no) | 2007-06-04 |
Family
ID=26531087
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20020814A NO323514B1 (no) | 1999-08-20 | 2002-02-19 | Nye spiroforbindelser, fremgangsmate for fremstilling av slike, samt nevnte spiroforbindelser for medisinsk bruk. |
Country Status (36)
Country | Link |
---|---|
US (3) | US6326375B1 (no) |
EP (1) | EP1204663B1 (no) |
KR (1) | KR100749713B1 (no) |
CN (2) | CN100457757C (no) |
AR (1) | AR029000A1 (no) |
AT (1) | ATE253064T1 (no) |
AU (1) | AU767229B2 (no) |
BG (1) | BG65805B1 (no) |
BR (1) | BR0013423A (no) |
CA (1) | CA2379103C (no) |
CO (1) | CO5200768A1 (no) |
CZ (1) | CZ2002533A3 (no) |
DE (1) | DE60006251T2 (no) |
DK (1) | DK1204663T3 (no) |
DZ (1) | DZ3175A1 (no) |
EA (1) | EA004507B1 (no) |
EE (1) | EE05248B1 (no) |
ES (1) | ES2206287T3 (no) |
GE (1) | GEP20053488B (no) |
HK (1) | HK1043123B (no) |
HR (1) | HRP20020102B1 (no) |
HU (1) | HUP0203107A3 (no) |
IL (1) | IL148119A0 (no) |
IS (1) | IS2420B (no) |
MX (1) | MXPA02001693A (no) |
MY (1) | MY130769A (no) |
NO (1) | NO323514B1 (no) |
NZ (1) | NZ517057A (no) |
PE (1) | PE20010645A1 (no) |
PL (1) | PL353743A1 (no) |
PT (1) | PT1204663E (no) |
RS (1) | RS50484B (no) |
SK (1) | SK286609B6 (no) |
TR (1) | TR200200408T2 (no) |
TW (1) | TWI279402B (no) |
WO (1) | WO2001014376A1 (no) |
Families Citing this family (130)
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US6374762B1 (en) * | 1997-10-27 | 2002-04-23 | Correct Craft, Inc. | Water sport towing apparatus |
US6462053B1 (en) * | 1999-08-20 | 2002-10-08 | Banyu Pharmaceutical Co., Ltd. | Spiro compounds |
US6803372B2 (en) * | 1999-08-20 | 2004-10-12 | Banyu Pharmaceutical Co., Ltd. | Spiro compounds |
CA2424622A1 (en) * | 2000-10-03 | 2002-04-11 | Clyde W. Hodge | Use of neuropeptide-y antagonists in treatment of alcoholism |
JP2004520299A (ja) * | 2000-12-12 | 2004-07-08 | ニューロジェン・コーポレーション | スピロ[イソベンゾフラン−1,4’−ピペリジン]−3−オン類及び3h−スピロイソベンゾフラン−1,4’−ピペリジン類 |
EP1695977A3 (en) * | 2000-12-12 | 2006-09-20 | Neurogen Corporation | Spiro [isobenzofuran-1,4'piperidin]-3-ones and 3H-spiroisobenzofuran-1, 4'-piperidines |
ES2316486T3 (es) | 2000-12-21 | 2009-04-16 | Schering Corporation | Antagonsitas de los receptores y5 del neuropeptido y heteroaril-urea. |
US6946476B2 (en) | 2000-12-21 | 2005-09-20 | Schering Corporation | Heteroaryl urea neuropeptide Y Y5 receptor antagonists |
US6924291B2 (en) | 2001-01-23 | 2005-08-02 | Merck & Co., Inc. | Process for making spiro isobenzofuranone compounds |
WO2002094825A1 (fr) * | 2001-05-22 | 2002-11-28 | Banyu Pharmaceutical Co., Ltd. | Nouveau derive de spiropiperidine |
CA2454228C (en) | 2001-07-24 | 2011-03-22 | Merck & Co., Inc. | Radiolabeled neuropeptide y y5 receptor antagonists |
DE60231880D1 (de) * | 2001-08-07 | 2009-05-20 | Banyu Pharma Co Ltd | Spiro isobenzofurane als neuropeptid y rezeptor antagonisten |
CA2469790A1 (en) * | 2001-12-17 | 2003-06-26 | Merck & Co., Inc. | Method for treating circadian rhythm disruptions |
WO2003051397A1 (en) * | 2001-12-17 | 2003-06-26 | Merck & Co., Inc. | Neuropeptide y5 receptor antagonists for treating depression, anxiety and dementia |
US6605720B1 (en) | 2002-01-28 | 2003-08-12 | Merck & Co., Inc. | Process for making spirolactone compounds |
NZ534757A (en) * | 2002-03-12 | 2006-07-28 | Merck & Co Inc | Substituted amides |
US7109207B2 (en) * | 2002-06-27 | 2006-09-19 | Schering Corporation | Spirosubstituted piperidines as selective melanin concentrating hormone receptor antagonists for the treatment of obesity |
US7105526B2 (en) * | 2002-06-28 | 2006-09-12 | Banyu Pharmaceuticals Co., Ltd. | Benzimidazole derivatives |
WO2004005262A2 (en) * | 2002-07-02 | 2004-01-15 | Schering Corporation | New neuropeptide y y5 receptor antagonists |
AU2003253925A1 (en) * | 2002-07-18 | 2004-02-09 | Banyu Pharmaceutical Co., Ltd. | Combination therapy for the treatment of obesity |
EP1558605A2 (en) * | 2002-10-18 | 2005-08-03 | Merck & Co., Inc. | Process for making spirolactone compounds |
EP1566384B1 (en) | 2002-11-29 | 2009-06-17 | Banyu Pharmaceutical Co., Ltd. | Novel azole derivatives |
US20040122033A1 (en) * | 2002-12-10 | 2004-06-24 | Nargund Ravi P. | Combination therapy for the treatment of obesity |
WO2004058264A1 (en) * | 2002-12-24 | 2004-07-15 | Biofocus Plc | Compound libraries of 2h-spiro (isoquinoline-1, -piperidine derivatives and related compounds for targetting compounds capable of binding to the g-protein receptor |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
AR044283A1 (es) * | 2003-05-19 | 2005-09-07 | Merck & Co Inc | Procedimeinto para preparar compuestos de espirolactona |
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US20060160834A1 (en) * | 2003-06-06 | 2006-07-20 | Fong Tung M | Combination therapy for the treatment of hypertension |
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ATE472531T1 (de) | 2004-08-06 | 2010-07-15 | Merck Sharp & Dohme | Sulfonylverbindungen als hemmer von 11-beta- hydroxysteroiddehydrogenase-1 |
MX2007002033A (es) | 2004-08-19 | 2007-04-26 | Vertex Pharma | Moduladores de receptores muscarinicos. |
US7786141B2 (en) * | 2004-08-19 | 2010-08-31 | Vertex Pharmaceuticals Incorporated | Dihydrospiroindene modulators of muscarinic receptors |
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US8394765B2 (en) * | 2004-11-01 | 2013-03-12 | Amylin Pharmaceuticals Llc | Methods of treating obesity with two different anti-obesity agents |
ES2325773T5 (es) | 2004-11-01 | 2014-02-24 | Amylin Pharmaceuticals, Llc. | Tratamiento de la obesidad y de los trastornos relacionados |
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JPWO2007024004A1 (ja) | 2005-08-24 | 2009-03-05 | 萬有製薬株式会社 | フェニルピリドン誘導体 |
EP1939194A4 (en) | 2005-09-07 | 2010-12-08 | Banyu Pharma Co Ltd | AROMATIC SUBSTITUTED BICYLIC PYRIDONE DERIVATIVE |
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JP5593234B2 (ja) * | 2008-03-11 | 2014-09-17 | ユニバーシティー ヘルス ネットワーク | ニューロペプチドy5r(npy5r)アンタゴニストを使用して癌を治療する方法 |
JPWO2009119726A1 (ja) | 2008-03-28 | 2011-07-28 | Msd株式会社 | メラニン凝集ホルモン受容体拮抗作用を有するジアリールメチルアミド誘導体 |
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