NO20005928L - Bicykliske pyrimidiner og bicykliske 3,4-dihydropyrimidiner som inhibitorer av cellulær proliferasjon - Google Patents
Bicykliske pyrimidiner og bicykliske 3,4-dihydropyrimidiner som inhibitorer av cellulær proliferasjonInfo
- Publication number
- NO20005928L NO20005928L NO20005928A NO20005928A NO20005928L NO 20005928 L NO20005928 L NO 20005928L NO 20005928 A NO20005928 A NO 20005928A NO 20005928 A NO20005928 A NO 20005928A NO 20005928 L NO20005928 L NO 20005928L
- Authority
- NO
- Norway
- Prior art keywords
- bicyclic
- dihydropyrimidines
- inhibitors
- cellular proliferation
- pyrimidines
- Prior art date
Links
- -1 Bicyclic pyrimidines Chemical class 0.000 title 2
- 230000004663 cell proliferation Effects 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8670898P | 1998-05-26 | 1998-05-26 | |
| US12615899P | 1999-03-25 | 1999-03-25 | |
| PCT/US1999/010187 WO1999061444A2 (en) | 1998-05-26 | 1999-05-10 | Bicyclic pyrimidines and bicyclic 3,4-dihydropyrimidines as inhibitors of cellular proliferation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20005928L true NO20005928L (no) | 2000-11-23 |
| NO20005928D0 NO20005928D0 (no) | 2000-11-23 |
Family
ID=26775058
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20005928A NO20005928D0 (no) | 1998-05-26 | 2000-11-23 | Bicykliske pyrimidiner og bicykliske 3,4-dihydropyrimidiner som inhibitorer av cellulær proliferasjon |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US7501425B1 (no) |
| EP (1) | EP1080092B1 (no) |
| JP (1) | JP2002516327A (no) |
| KR (1) | KR20010043829A (no) |
| CN (1) | CN1138778C (no) |
| AP (1) | AP2000001964A0 (no) |
| AT (1) | ATE402177T1 (no) |
| AU (1) | AU763839B2 (no) |
| BG (1) | BG104960A (no) |
| BR (1) | BR9911590A (no) |
| CA (1) | CA2329703C (no) |
| DE (1) | DE69939168D1 (no) |
| EA (1) | EA003640B1 (no) |
| EE (1) | EE200000706A (no) |
| ES (1) | ES2310039T3 (no) |
| GE (1) | GEP20033093B (no) |
| HR (1) | HRP20000799A2 (no) |
| HU (1) | HUP0102514A3 (no) |
| ID (1) | ID27589A (no) |
| IL (1) | IL139599A0 (no) |
| IS (1) | IS5687A (no) |
| NO (1) | NO20005928D0 (no) |
| NZ (1) | NZ508268A (no) |
| PL (1) | PL344248A1 (no) |
| SK (1) | SK17532000A3 (no) |
| TR (1) | TR200003429T2 (no) |
| WO (1) | WO1999061444A2 (no) |
| YU (1) | YU73300A (no) |
Families Citing this family (108)
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|---|---|---|---|---|
| TR200003429T2 (tr) | 1998-05-26 | 2001-07-23 | Warner-Lambert Company | Hücresel çoğalma inhibitörleri olarak bisiklik pirimidinler ve bisiklik 3,4-dihidropirimidinler. |
| TR200101102T2 (tr) * | 1998-10-23 | 2002-01-21 | F.Hoffmann-La Roche Ag | Bisiklik nitrojen heterosikleler |
| IL149100A0 (en) * | 1999-10-21 | 2002-11-10 | Hoffmann La Roche | Heteroalkylamino-substituted bicyclic nitrogen heterocycles as inhibitors of p38 protein kinase |
| MXPA02003841A (es) * | 1999-10-21 | 2002-09-30 | Hoffmann La Roche | Heterociclos de nitrogeno biciclicos alquilamino substituidos como inhibidores de proteina p38. |
| AP2002002603A0 (en) * | 2000-01-24 | 2002-09-30 | Warner Lambert Co | 3-aminoquinazolin-2,4-dione antibacterial agents. |
| US7053070B2 (en) | 2000-01-25 | 2006-05-30 | Warner-Lambert Company | Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors |
| BR0107751A (pt) * | 2000-01-25 | 2002-11-12 | Warner Lambert Co | Inibidores de pirido[2,3-d]pirimidina-2,7-diaminas quinase |
| AR030053A1 (es) * | 2000-03-02 | 2003-08-13 | Smithkline Beecham Corp | 1h-pirimido [4,5-d] pirimidin-2-onas y sales, composiciones farmaceuticas, uso para la fabricacion de un medicamento y procedimiento para producirlas |
| US7235551B2 (en) * | 2000-03-02 | 2007-06-26 | Smithkline Beecham Corporation | 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases |
| CN1422268A (zh) * | 2000-03-06 | 2003-06-04 | 沃尼尔·朗伯公司 | 5-烷基吡啶并[2,3-d]嘧啶酪氨酸激酶抑制剂 |
| US6506749B2 (en) | 2000-08-31 | 2003-01-14 | Syntex (U.S.A.) Llc | 7-oxo-pyridopyrimidines (I) |
| JP4141830B2 (ja) * | 2000-08-31 | 2008-08-27 | エフ.ホフマン−ラ ロシュ アーゲー | 細胞増殖の阻害剤としての7−オキソ−ピリドピリミジン類 |
| ATE521353T1 (de) | 2000-10-23 | 2011-09-15 | Glaxosmithkline Llc | Neues trisubstitutiertes 8h-pyridoä2,3- düpyrimidin-7-onderivat zur behandlung von durch csbp/p38kinase vermittelten krankheiten |
| GB0029015D0 (en) | 2000-11-28 | 2001-01-10 | Univ London | Medical device |
| AU2002251788A1 (en) | 2001-01-19 | 2002-08-12 | Smithkline Beecham Corporation | Novel compounds and uses thereof |
| JP4064818B2 (ja) | 2001-02-12 | 2008-03-19 | エフ.ホフマン−ラ ロシュ アーゲー | 6−置換ピリド−ピリミジン類 |
| US7105667B2 (en) | 2001-05-01 | 2006-09-12 | Bristol-Myers Squibb Co. | Fused heterocyclic compounds and use thereof |
| EP1395585B1 (en) | 2001-05-30 | 2006-01-04 | Warner-Lambert Company LLC | Antibacterial agents |
| DE60303009T2 (de) * | 2002-01-22 | 2006-07-13 | Warner-Lambert Co. Llc | 2-(pyridin-2-ylamino)-pyrido[2,3-d]pyrimidin-7-one |
| US7176310B1 (en) | 2002-04-09 | 2007-02-13 | Ucb Sa | Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents |
| ES2291630T3 (es) | 2002-04-19 | 2008-03-01 | Smithkline Beecham Corporation | Nuevos compuestos. |
| US7196090B2 (en) * | 2002-07-25 | 2007-03-27 | Warner-Lambert Company | Kinase inhibitors |
| ES2293064T3 (es) | 2002-08-06 | 2008-03-16 | F. Hoffmann-La Roche Ag | 6-alcoxi-pirido-pirimidinas como inhibidores de la p-38 map quinasa. |
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| TW200413381A (en) | 2002-11-04 | 2004-08-01 | Hoffmann La Roche | Novel amino-substituted dihydropyrimido [4,5-d]pyrimidinone derivatives, their manufacture and use as pharmaceutical agents |
| US7129351B2 (en) * | 2002-11-04 | 2006-10-31 | Hoffmann-La Roche Inc. | Pyrimido compounds having antiproliferative activity |
| BRPI0406809A (pt) * | 2003-01-17 | 2005-12-27 | Warner Lambert Co | Heterociclos substituìdos de 2-aminopiridina como inibidores da proliferação celular |
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| DE10325133A1 (de) * | 2003-06-04 | 2004-12-23 | Bayer Cropscience Ag | Triazolopyrimidine |
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| RU2348632C2 (ru) | 2003-11-13 | 2009-03-10 | Ф.Хоффманн-Ля Рош Аг | Гидроксиалкилзамещенные пиридо-7-пиримидин-7-оны |
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| JP2008509964A (ja) * | 2004-08-31 | 2008-04-03 | エフ.ホフマン−ラ ロシュ アーゲー | 7−アミノ−3−フェニル−ジヒドロピリミド[4,5−d]ピリミジノンのアミド誘導体、これらの製造、及びプロテインキナーゼ阻害剤としての使用 |
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| US20090137550A1 (en) | 2005-03-25 | 2009-05-28 | Glaxo Group Limited | Novel Compounds |
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| CA2636981A1 (en) | 2006-01-31 | 2007-08-09 | F. Hoffmann-La Roche Ag | 7h-pyrido[3,4-d]pyrimidin-8-ones, their manufacture and use as protein kinase inhibitors |
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1999
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