NO20005928D0 - Bicykliske pyrimidiner og bicykliske 3,4-dihydropyrimidiner som inhibitorer av cellulær proliferasjon - Google Patents
Bicykliske pyrimidiner og bicykliske 3,4-dihydropyrimidiner som inhibitorer av cellulær proliferasjonInfo
- Publication number
- NO20005928D0 NO20005928D0 NO20005928A NO20005928A NO20005928D0 NO 20005928 D0 NO20005928 D0 NO 20005928D0 NO 20005928 A NO20005928 A NO 20005928A NO 20005928 A NO20005928 A NO 20005928A NO 20005928 D0 NO20005928 D0 NO 20005928D0
- Authority
- NO
- Norway
- Prior art keywords
- bicyclic
- dihydropyrimidines
- inhibitors
- cellular proliferation
- pyrimidines
- Prior art date
Links
- -1 Bicyclic pyrimidines Chemical class 0.000 title 2
- 230000004663 cell proliferation Effects 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8670898P | 1998-05-26 | 1998-05-26 | |
| US12615899P | 1999-03-25 | 1999-03-25 | |
| PCT/US1999/010187 WO1999061444A2 (en) | 1998-05-26 | 1999-05-10 | Bicyclic pyrimidines and bicyclic 3,4-dihydropyrimidines as inhibitors of cellular proliferation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20005928D0 true NO20005928D0 (no) | 2000-11-23 |
| NO20005928L NO20005928L (no) | 2000-11-23 |
Family
ID=26775058
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20005928A NO20005928L (no) | 1998-05-26 | 2000-11-23 | Bicykliske pyrimidiner og bicykliske 3,4-dihydropyrimidiner som inhibitorer av cellulær proliferasjon |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US7501425B1 (no) |
| EP (1) | EP1080092B1 (no) |
| JP (1) | JP2002516327A (no) |
| KR (1) | KR20010043829A (no) |
| CN (1) | CN1138778C (no) |
| AP (1) | AP2000001964A0 (no) |
| AT (1) | ATE402177T1 (no) |
| AU (1) | AU763839B2 (no) |
| BG (1) | BG104960A (no) |
| BR (1) | BR9911590A (no) |
| CA (1) | CA2329703C (no) |
| DE (1) | DE69939168D1 (no) |
| EA (1) | EA003640B1 (no) |
| EE (1) | EE200000706A (no) |
| ES (1) | ES2310039T3 (no) |
| GE (1) | GEP20033093B (no) |
| HR (1) | HRP20000799A2 (no) |
| HU (1) | HUP0102514A3 (no) |
| ID (1) | ID27589A (no) |
| IL (1) | IL139599A0 (no) |
| IS (1) | IS5687A (no) |
| NO (1) | NO20005928L (no) |
| NZ (1) | NZ508268A (no) |
| PL (1) | PL344248A1 (no) |
| SK (1) | SK17532000A3 (no) |
| TR (1) | TR200003429T2 (no) |
| WO (1) | WO1999061444A2 (no) |
| YU (1) | YU73300A (no) |
Families Citing this family (108)
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|---|---|---|---|---|
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| WO2001029042A1 (en) | 1999-10-21 | 2001-04-26 | F. Hoffmann-La Roche Ag | Heteroalkylamino-substituted bicyclic nitrogen heterocycles as inhibitors of p38 protein kinase |
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| AP2002002586A0 (en) * | 2000-01-25 | 2002-09-30 | Warner Lambert Co | Pyrido[2,3-d] pyrimidine-2,7-diamine kinase inhibitors. |
| US7053070B2 (en) | 2000-01-25 | 2006-05-30 | Warner-Lambert Company | Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors |
| US7235551B2 (en) * | 2000-03-02 | 2007-06-26 | Smithkline Beecham Corporation | 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases |
| AR030053A1 (es) * | 2000-03-02 | 2003-08-13 | Smithkline Beecham Corp | 1h-pirimido [4,5-d] pirimidin-2-onas y sales, composiciones farmaceuticas, uso para la fabricacion de un medicamento y procedimiento para producirlas |
| HRP20020798A2 (en) * | 2000-03-06 | 2004-02-29 | Warner Lambert Co | 5-ALKYLPYRIDO[2,3-d]PYRIMIDINES TYROZINE KINASE INHIBITORS |
| BR0113628A (pt) * | 2000-08-31 | 2003-07-01 | Hoffmann La Roche | 7-oxo-piridopirimidinas como inibidores de uma proliferação celular |
| US6506749B2 (en) | 2000-08-31 | 2003-01-14 | Syntex (U.S.A.) Llc | 7-oxo-pyridopyrimidines (I) |
| JP4524072B2 (ja) | 2000-10-23 | 2010-08-11 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | 新規化合物 |
| GB0029015D0 (en) | 2000-11-28 | 2001-01-10 | Univ London | Medical device |
| ES2259079T3 (es) | 2001-01-19 | 2006-09-16 | Smithkline Beecham Corporation | Inhibidores de la actividad cinasa del receptor tie2 para tratar enfermedades angiogenicas. |
| HRP20030624B1 (en) | 2001-02-12 | 2007-03-31 | F. Hoffmann - La Roche Ag | 6-substituted pyrido-pyrimidines |
| US7105667B2 (en) | 2001-05-01 | 2006-09-12 | Bristol-Myers Squibb Co. | Fused heterocyclic compounds and use thereof |
| DE60208541D1 (de) | 2001-05-30 | 2006-03-30 | Warner Lambert Co | Antibakterielle mittel |
| WO2003062236A1 (en) * | 2002-01-22 | 2003-07-31 | Warner-Lambert Company Llc | 2-(PYRIDIN-2-YLAMINO)-PYRIDO[2,3d]PYRIMIDIN-7-ONES |
| US7176310B1 (en) | 2002-04-09 | 2007-02-13 | Ucb Sa | Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents |
| US7629350B2 (en) | 2002-04-19 | 2009-12-08 | Smithkline Beecham Corporation | Compounds |
| PA8577501A1 (es) * | 2002-07-25 | 2004-02-07 | Warner Lambert Co | Inhibidores de quinasas |
| CA2492112A1 (en) | 2002-08-06 | 2004-02-19 | F. Hoffmann-La Roche Ag | 6-alkoxy-pyrido-pyrimidines as p-38 map kinase inhibitors |
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| TW202313611A (zh) | 2021-06-09 | 2023-04-01 | 美商英塞特公司 | 作為fgfr抑制劑之三環雜環 |
| EP4352060A1 (en) | 2021-06-09 | 2024-04-17 | Incyte Corporation | Tricyclic heterocycles as fgfr inhibitors |
| CR20240447A (es) | 2022-03-17 | 2025-01-29 | Incyte Corp | Compuestos de urea tricíclica como inhibidores de v617f de jak2. |
| WO2024199388A1 (zh) * | 2023-03-29 | 2024-10-03 | 微境生物医药科技(上海)有限公司 | 作为myt1抑制剂的化合物 |
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1999
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- 1999-05-10 HU HU0102514A patent/HUP0102514A3/hu unknown
- 1999-05-10 DE DE69939168T patent/DE69939168D1/de not_active Expired - Fee Related
- 1999-05-10 KR KR1020007013279A patent/KR20010043829A/ko not_active Ceased
- 1999-05-10 US US09/623,737 patent/US7501425B1/en not_active Expired - Fee Related
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- 1999-05-10 BR BR9911590-5A patent/BR9911590A/pt not_active Application Discontinuation
- 1999-05-10 PL PL99344248A patent/PL344248A1/xx not_active Application Discontinuation
- 1999-05-10 AU AU40734/99A patent/AU763839B2/en not_active Ceased
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- 1999-05-10 HR HR20000799A patent/HRP20000799A2/hr not_active Application Discontinuation
- 1999-05-10 JP JP2000550849A patent/JP2002516327A/ja not_active Abandoned
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- 1999-05-10 CN CNB998065587A patent/CN1138778C/zh not_active Expired - Fee Related
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