NO176914C - Macrolidforbindelser, fremgangsmåte for deres fremstilling, biologisk renset kultur samt preparater inneholdende macrolidforbindelsene - Google Patents

Macrolidforbindelser, fremgangsmåte for deres fremstilling, biologisk renset kultur samt preparater inneholdende macrolidforbindelsene

Info

Publication number
NO176914C
NO176914C NO895096A NO895096A NO176914C NO 176914 C NO176914 C NO 176914C NO 895096 A NO895096 A NO 895096A NO 895096 A NO895096 A NO 895096A NO 176914 C NO176914 C NO 176914C
Authority
NO
Norway
Prior art keywords
macrolide compounds
methods
compounds
preparation
preparations containing
Prior art date
Application number
NO895096A
Other languages
English (en)
Norwegian (no)
Other versions
NO176914B (no
NO895096D0 (no
NO895096L (no
Inventor
Laverne Dwaine Boeck
Hang Chio
Tom Edward Eaton
Otis Webster Godfrey Jr
Karl Heinz Michel
Walter Mitsuo Nakatsukasa
Raymond Che-Fong Yao
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO895096D0 publication Critical patent/NO895096D0/no
Publication of NO895096L publication Critical patent/NO895096L/no
Publication of NO176914B publication Critical patent/NO176914B/no
Publication of NO176914C publication Critical patent/NO176914C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Electrotherapy Devices (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
NO895096A 1988-12-19 1989-12-18 Macrolidforbindelser, fremgangsmåte for deres fremstilling, biologisk renset kultur samt preparater inneholdende macrolidforbindelsene NO176914C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28659188A 1988-12-19 1988-12-19
US42944189A 1989-10-30 1989-10-30

Publications (4)

Publication Number Publication Date
NO895096D0 NO895096D0 (no) 1989-12-18
NO895096L NO895096L (no) 1990-06-20
NO176914B NO176914B (no) 1995-03-13
NO176914C true NO176914C (no) 1995-06-21

Family

ID=26963932

Family Applications (1)

Application Number Title Priority Date Filing Date
NO895096A NO176914C (no) 1988-12-19 1989-12-18 Macrolidforbindelser, fremgangsmåte for deres fremstilling, biologisk renset kultur samt preparater inneholdende macrolidforbindelsene

Country Status (32)

Country Link
US (2) US5496931A (bg)
EP (1) EP0375316B1 (bg)
JP (1) JP2535080B2 (bg)
KR (1) KR0143566B1 (bg)
CN (1) CN1035391C (bg)
AT (1) ATE116325T1 (bg)
AU (1) AU624458B2 (bg)
BG (1) BG60520B1 (bg)
BR (1) BR8906547A (bg)
CA (1) CA2005784C (bg)
CZ (1) CZ285992B6 (bg)
DE (2) DE68920301T2 (bg)
DK (1) DK174489B1 (bg)
DZ (1) DZ1375A1 (bg)
EG (1) EG19191A (bg)
ES (1) ES2065398T3 (bg)
FI (2) FI95601C (bg)
GR (1) GR3015598T3 (bg)
HU (1) HU208998B (bg)
IE (1) IE65919B1 (bg)
IL (1) IL92743A (bg)
IN (1) IN169756B (bg)
MA (1) MA21697A1 (bg)
MY (1) MY111148A (bg)
NL (1) NL350009I2 (bg)
NO (1) NO176914C (bg)
NZ (1) NZ231831A (bg)
OA (1) OA09249A (bg)
PE (1) PE5591A1 (bg)
PL (1) PL161476B1 (bg)
PT (1) PT92607B (bg)
YU (1) YU47099B (bg)

Families Citing this family (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5362634A (en) * 1989-10-30 1994-11-08 Dowelanco Process for producing A83543 compounds
OA09249A (fr) * 1988-12-19 1992-06-30 Lilly Co Eli Composés de macrolides.
US5227295A (en) * 1991-11-08 1993-07-13 Dowelanco Process for isolating A83543 and its components
US5539089A (en) * 1991-11-08 1996-07-23 Dowelanco A83543 aglycones and pseudoglycones
US5202242A (en) * 1991-11-08 1993-04-13 Dowelanco A83543 compounds and processes for production thereof
CN1073483A (zh) * 1991-11-08 1993-06-23 道伊兰科公司 一种发酵杀虫剂化合物及其制备方法
US5591606A (en) * 1992-11-06 1997-01-07 Dowelanco Process for the production of A83543 compounds with Saccharopolyspora spinosa
TR28273A (tr) * 1992-12-09 1996-04-25 Dowelanco Yeni a83543 bilesikleri ve bunlari üretmeye mahsus yöntem.
ATE150758T1 (de) * 1993-03-12 1997-04-15 Dowelanco Neue a83543 verbindungen und verfahren zu ihrer herstellung
CN1130369C (zh) * 1995-06-14 2003-12-10 道农业科学公司 对刺糖多孢菌素化合物的合成修饰
US6001981A (en) * 1996-06-13 1999-12-14 Dow Agrosciences Llc Synthetic modification of Spinosyn compounds
GB9624501D0 (en) * 1996-11-26 1997-01-15 Zeneca Ltd Insecticial compositions and method
ID27789A (id) * 1997-12-23 2001-04-26 Novartis Ag Penggunaan makrolida untuk mengendalikan hama
DE19823396A1 (de) * 1998-05-26 1999-12-02 Bayer Ag Synergistische insektizide Mischungen
DE19823397B4 (de) * 1998-05-26 2011-07-28 Bayer CropScience AG, 40789 Verwendung von Spinosynen zum Einsatz als Bodeninsektizide
WO2000001347A2 (en) * 1998-07-02 2000-01-13 Eli Lilly And Company Formulations for controlling human lice
DE19857967A1 (de) * 1998-12-16 2000-06-21 Bayer Ag Wirkstoffkombinationen
AU775488B2 (en) * 1999-08-12 2004-08-05 Elanco Us Inc. Oral treatment of companion animals with ectoparasiticidal spinosyns
AU770879B2 (en) * 1999-08-12 2004-03-04 Eli Lilly And Company Ectoparasiticidal aqueous suspension formulations of spinosyns
US6927210B1 (en) 1999-08-12 2005-08-09 Eli Lilly And Company Ectoparasiticidal aqueous suspension formulations of spinosyns
AU6605300A (en) * 1999-08-12 2001-03-13 Eli Lilly And Company Control of ectoparasites using spinosyns
AU6606400A (en) * 1999-08-12 2001-03-13 Eli Lilly And Company Topical treatment for insect pests in companion animals
US6933318B1 (en) 1999-08-12 2005-08-23 Eli Lilly And Company Topical organic ectoparasiticidal formulations
KR100731248B1 (ko) * 1999-09-13 2007-06-25 다우 아그로사이언시즈 엘엘씨 살충제 마크롤라이드
AUPQ441699A0 (en) 1999-12-02 2000-01-06 Eli Lilly And Company Pour-on formulations
AUPQ634300A0 (en) * 2000-03-20 2000-04-15 Eli Lilly And Company Synergistic formulations
DE10013914A1 (de) 2000-03-21 2001-09-27 Bayer Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
US6682925B1 (en) * 2000-04-13 2004-01-27 Agraquest, Inc. Streptomyces strain with insecticidal activity and method of using as an insecticide
DE10055941A1 (de) * 2000-11-10 2002-05-23 Bayer Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
US6585990B1 (en) 2001-03-05 2003-07-01 Dow Agrosciences, Llc Compositions and devices using a spinosyn compound for control of insects
IL157974A0 (en) 2001-03-21 2004-03-28 Dow Agrosciences Llc Pesticidal macrolides
TWI275592B (en) * 2001-03-21 2007-03-11 Dow Agrosciences Llc Synthetic derivatives of 21-butenyl and related spinosyns
DK1373245T3 (da) * 2001-03-29 2007-04-10 Bayer Cropscience Ag Mellemprodukter til fremstilling af spinosyner
US6727228B2 (en) * 2001-04-25 2004-04-27 Johnson & Johnson Consumer Companies, Inc. Pediculicidal and ovacidal treatment compositions and methods for killing head lice and their eggs
DE10135550A1 (de) * 2001-07-20 2003-01-30 Bayer Cropscience Ag Verfahren zum Herstellen von neuen Spinosyn-Derivaten
AR036872A1 (es) 2001-08-13 2004-10-13 Du Pont Compuesto de antranilamida, composicion que lo comprende y metodo para controlar una plaga de invertebrados
US20090227452A1 (en) * 2001-09-14 2009-09-10 Birthisel Timothy D Spent fermented grain soil additive
HUP0500984A3 (en) 2001-09-17 2007-02-28 Lilly Co Eli Synergetic pesticidal formulations
JP2005504832A (ja) * 2001-10-08 2005-02-17 イーライ・リリー・アンド・カンパニー 甲虫を防除する方法
TWI330183B (bg) * 2001-10-22 2010-09-11 Eisai R&D Man Co Ltd
US20030225006A1 (en) 2002-02-19 2003-12-04 Burns Lesley S Novel spinosyn-producing polyketide synthases
DE10248257A1 (de) * 2002-10-16 2004-04-29 Bayer Cropscience Ag Wirkstoffkombinationen im insektiziden und akariziden Eigenschaften
DE10320505A1 (de) 2003-05-08 2004-11-25 Bayer Healthcare Ag Mittel zum Bekämpfen von Parasiten an Tieren
DE10333371A1 (de) * 2003-07-23 2005-02-10 Bayer Ag Fungizide Wirkstoffkombinationen
DE602004017347D1 (de) * 2003-11-04 2008-12-04 Intervet Int Bv Azol-pestiziden
DE10353281A1 (de) 2003-11-14 2005-06-16 Bayer Cropscience Ag Wirkstoffkombination mit insektiziden und akariziden Eigenschaften
AU2006249441A1 (en) * 2005-05-26 2006-11-30 Eli Lilly And Company Improved fish production
EP1849363A1 (en) * 2006-03-09 2007-10-31 Cheminova A/S Synergistic combination of glutamate- and GABA-gated chloride agonist pesticide and at least one of Vitamin E or Niacin
ES2477465T3 (es) * 2006-05-25 2014-07-17 Dow Agrosciences, Llc Fumigantes de espinosina
DE102007045922A1 (de) 2007-09-26 2009-04-02 Bayer Cropscience Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
EP2070416A1 (de) 2007-12-11 2009-06-17 Bayer CropScience AG Verwendung von Wirkstoffkombinationen zur Bekämpfung von tierischen Schädlingen
EP2127522A1 (de) 2008-05-29 2009-12-02 Bayer CropScience AG Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
US8470381B2 (en) * 2008-09-22 2013-06-25 Christine Kritikou Spinosyn antifouling compositions, methods of use thereof and articles protected from attachment of biofouling organisms
EP2227951A1 (de) 2009-01-23 2010-09-15 Bayer CropScience AG Verwendung von Enaminocarbonylverbindungen zur Bekämpfung von durch Insekten übertragenen Viren
TW201041507A (en) 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity and methods for preparing same
TW201041510A (en) * 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
TW201041508A (en) * 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
TW201041509A (en) * 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
WO2010150100A1 (en) 2009-06-24 2010-12-29 Entarco Sa The use of spinosyns and spinosyn compositions against diseases caused by protozoans, viral infections and cancer
US8541216B2 (en) * 2009-11-06 2013-09-24 Bayer Cropscience Lp Insecticidal fermentation broth from actinomycetes containing enhanced ratio of active to inactive dunaimycins
WO2011091122A1 (en) * 2010-01-25 2011-07-28 Eli Lilly And Company Methods for internally controlling or treating equine bot larvae
TWI513407B (zh) * 2010-02-19 2015-12-21 Sumitomo Chemical Co 害蟲控制組成物
EP2382865A1 (de) 2010-04-28 2011-11-02 Bayer CropScience AG Synergistische Wirkstoffkombinationen
WO2011143291A1 (en) 2010-05-11 2011-11-17 Dow Agrosciences Llc Spnk strains
DE112011101358T5 (de) 2010-09-29 2013-02-07 Tokai Rubber Industries, Ltd. Kautschukzusammensetzung für einen Wasserschlauch und Wasserschlauch, der unter Verwendung der Kautschukzusammensetzung erhalten worden ist
AU2011323082B2 (en) 2010-11-05 2015-06-11 Eli Lilly And Company Methods for inhibiting insect infestations
EP2654757A1 (en) 2010-12-22 2013-10-30 Entarco SA The use of spinosyns and spinosyn compositions as local anesthetics and as antiarrhythmic agents
WO2012141754A2 (en) 2010-12-29 2012-10-18 Dow Agrosciences Llc Methods of controlling insects
HUE034838T2 (en) 2011-05-03 2018-03-28 Dow Agrosciences Llc Integration of genes into chromosome of saccharopolyspora spinosa
JP5760781B2 (ja) 2011-07-13 2015-08-12 住友化学株式会社 有害節足動物防除組成物及び有害節足動物の防除方法
US9631195B2 (en) 2011-12-28 2017-04-25 Dow Agrosciences Llc Identification and characterization of the spinactin biosysnthesis gene cluster from spinosyn producing saccharopolyspora spinosa
DE112013000869T5 (de) 2012-02-06 2014-10-16 Merial Ltd. Orale parasitizide Veterinärzusammensetzungen umfassend systemisch wirkende Wirkstoffe, Verfahren und Verwendun davon
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
US9895388B1 (en) * 2012-07-27 2018-02-20 ParaPRO Methods and compositions useful for controlling cutaneous mites
US20150250166A1 (en) 2012-08-23 2015-09-10 Allylix, Inc. Nootkatone as an insecticide and insect repellent
US9839214B2 (en) 2012-12-18 2017-12-12 Evolva, Inc. Solavetivone and 5-epi-beta-vertivone as pest repellants and pesticides
BR112016023898A8 (pt) 2014-04-17 2021-03-30 Basf Se uso de compostos malononitrila para proteger animais de parasitas
WO2015179414A1 (en) 2014-05-19 2015-11-26 Merial, Inc. Anthelmintic compounds
AU2015276941B2 (en) 2014-06-19 2018-07-19 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising indole derivatives, methods and uses thereof
US10306887B2 (en) 2014-08-05 2019-06-04 The Board Of Regents Of The University Of Texas Systems Composition and methods for modulation of the octopamine receptor and its homologs
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
SG10202103403SA (en) 2015-05-20 2021-05-28 Boehringer Ingelheim Animal Health Usa Inc Anthelmintic depsipeptide compounds
CN112386603B (zh) * 2015-06-01 2021-10-01 中南大学 多杀菌素衍生物在制备抗肿瘤药物和抗kshv病毒药物方面的应用
WO2017133938A2 (en) 2016-02-01 2017-08-10 Bayer Animal Health Gmbh Rhipicephalus nicotinic acetylcholine receptor and pest control acting thereon
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
EP3541789A1 (en) 2016-11-16 2019-09-25 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
US20200115705A1 (en) 2017-06-06 2020-04-16 Zymergen Inc. A high-throughput (htp) genomic engineering platform for improving saccharopolyspora spinosa
US10494760B2 (en) 2017-12-12 2019-12-03 EctoGuard, LLC Methods and formulations for controlling human lice infestations
SG11202012922VA (en) 2018-07-09 2021-01-28 Boehringer Ingelheim Animal Health Usa Inc Anthelminthic heterocyclic compounds
WO2020023943A1 (en) 2018-07-27 2020-01-30 Aperta Biosciences, Llc Spinosyn formulations for treatment of demodex-induced ocular and facial conditions
EP3883648A1 (en) 2018-11-20 2021-09-29 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
NZ776819A (en) 2019-01-16 2023-04-28 Boehringer Ingelheim Animal Health Usa Inc Topical compositions comprising a neonicotinoid and a macrocyclic lactone, methods and uses thereof
PE20220281A1 (es) 2019-03-19 2022-02-25 Boehringer Ingelheim Animal Health Usa Inc Compuestos de aza-benzotiofeno y aza-benzofurano como antihelminticos
WO2020214901A1 (en) * 2019-04-17 2020-10-22 Boyce Thompson Institute For Plant Research, Inc. Compositions and methods for modulating immunity in plants
MX2022015038A (es) 2020-05-29 2023-01-04 Boehringer Ingelheim Animal Health Usa Inc Compuestos heterociclicos como anthelminticos.
CN113461757B (zh) * 2021-06-25 2023-08-22 湖州师范学院 新型十六元大环内酯的制备方法及用途
CN115785180A (zh) * 2022-12-19 2023-03-14 利民化学有限责任公司 作为杀虫剂的多杀菌素衍生物及其制备方法和应用

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2881162A (en) * 1953-11-16 1959-04-07 Abbott Lab Recovery process
US3725385A (en) * 1970-11-02 1973-04-03 Abbott Lab Process for the demethylation of 3-amino macrolides
US4206206A (en) * 1977-03-24 1980-06-03 Kowa Company, Ltd. Antibiotics of the KA-6606 series and pharmaceutical compositions thereof
AU520409B2 (en) * 1977-05-25 1982-01-28 Commonwealth Scientific And Industrial Research Organisation Controlled release composition
US4213966A (en) * 1977-06-02 1980-07-22 E. R. Squibb & Sons, Inc. Method for isolating polyether antibiotics
US4148883A (en) * 1977-08-18 1979-04-10 Pfizer Inc. Antibiotics produced by new species of nocardia
US4224314A (en) * 1979-03-02 1980-09-23 Pfizer Inc. Antibiotics produced by species of Nocardia
JPS5943929B2 (ja) * 1979-08-13 1984-10-25 サッポロビール株式会社 多糖体rbs物質,その製法およびそれを有効成分とする抗腫瘍性剤
US4273920A (en) * 1979-09-12 1981-06-16 Eli Lilly And Company Polymerization process and product
PH25589A (en) * 1979-09-12 1991-08-08 Lilly Co Eli Device for drug celivery to ruminants
US4293651A (en) * 1979-10-02 1981-10-06 The Upjohn Company Process for producing antibiotic using saccharopolyspora
US4251511A (en) * 1979-10-02 1981-02-17 The Upjohn Company Antibiotic and fermentation process of preparing
US4321329A (en) * 1979-10-02 1982-03-23 The Upjohn Company Saccharopolyspora culture
EP0043197A1 (en) * 1980-07-02 1982-01-06 Beecham Group Plc Beta-Lactam antibiotic, its preparation and use
DE3162169D1 (en) * 1980-07-15 1984-03-15 Kowa Co Process for production of antibiotics, and novel antibiotics produced thereby
US4448970A (en) * 1981-02-19 1984-05-15 The Upjohn Company Nargenicin derivatives
IT1195299B (it) * 1981-11-27 1988-10-12 Pierrel Spa Procedimento chimico di sintesi per la preparazione di antibiotici macrolidici
GB2111495B (en) * 1981-12-08 1985-04-17 Toyo Jozo Kk Aminoglycoside antibiotics
JPS58189114A (ja) * 1982-04-30 1983-11-04 Ss Pharmaceut Co Ltd 抗潰瘍剤
US4508647A (en) * 1982-07-26 1985-04-02 Bristol-Myers Company Antitumor antibiotics BBM-2040A and BBM-2040B
IT1194181B (it) * 1983-03-30 1988-09-14 Erba Farmitalia Procedimento migliorato per la purificazione della tilosina
US4530835A (en) * 1983-07-08 1985-07-23 Warner-Lambert Company CL-1577 Antibiotic compounds and their production
US4560509A (en) * 1983-11-16 1985-12-24 Eli Lilly And Company Antibiotic A39079 factor S-1
JPS625990A (ja) * 1985-06-20 1987-01-12 Sumitomo Chem Co Ltd 抗生物質およびその製造方法
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
US4831016A (en) * 1986-10-31 1989-05-16 Merck & Co., Inc. Reduced avermectin derivatives
US5003056A (en) * 1987-12-24 1991-03-26 Nippon Kayaku Kabushiki Kaisha Antibiotic NK86-0279, process for production of the same and application of the same
OA09249A (fr) * 1988-12-19 1992-06-30 Lilly Co Eli Composés de macrolides.
US5362634A (en) * 1989-10-30 1994-11-08 Dowelanco Process for producing A83543 compounds
US5028536A (en) * 1989-03-15 1991-07-02 Bristol-Myers Squibb Company Antitumor antibiotic BMY-41339
JPH05504469A (ja) * 1989-10-30 1993-07-15 ダウエランコ A83543回収方法
CN1073483A (zh) * 1991-11-08 1993-06-23 道伊兰科公司 一种发酵杀虫剂化合物及其制备方法
US5202242A (en) * 1991-11-08 1993-04-13 Dowelanco A83543 compounds and processes for production thereof
US5227295A (en) * 1991-11-08 1993-07-13 Dowelanco Process for isolating A83543 and its components

Also Published As

Publication number Publication date
AU4689189A (en) 1990-06-21
FI950946A0 (fi) 1995-03-01
DE68920301D1 (de) 1995-02-09
KR900009681A (ko) 1990-07-05
DK642089A (da) 1990-06-20
FI95601B (fi) 1995-11-15
EG19191A (en) 1994-09-29
MY111148A (en) 1999-09-30
CA2005784C (en) 1999-02-02
HU896661D0 (bg) 1990-03-28
EP0375316B1 (en) 1994-12-28
IN169756B (bg) 1991-12-21
PT92607A (pt) 1990-06-29
YU239389A (en) 1991-04-30
DE68920301T2 (de) 1995-07-06
KR0143566B1 (ko) 1998-07-15
PT92607B (pt) 1995-09-12
DE122007000053I2 (de) 2009-09-17
CZ285992B6 (cs) 1999-12-15
DK642089D0 (da) 1989-12-18
FI896053A0 (fi) 1989-12-18
HU208998B (en) 1994-02-28
IE65919B1 (en) 1995-11-29
US5571901A (en) 1996-11-05
BG60520B1 (bg) 1995-07-28
ES2065398T3 (es) 1995-02-16
FI96224C (fi) 1996-05-27
GR3015598T3 (en) 1995-06-30
CN1043742A (zh) 1990-07-11
CZ717089A3 (cs) 1999-08-11
DZ1375A1 (fr) 2004-09-13
NO176914B (no) 1995-03-13
US5496931A (en) 1996-03-05
FI96224B (fi) 1996-02-15
DK174489B1 (da) 2003-04-14
NL350009I2 (nl) 2003-08-01
BR8906547A (pt) 1990-09-04
IL92743A (en) 1994-10-21
MA21697A1 (fr) 1990-07-01
IE894068L (en) 1990-06-19
ATE116325T1 (de) 1995-01-15
IL92743A0 (en) 1990-09-17
EP0375316A1 (en) 1990-06-27
PE5591A1 (es) 1991-02-15
OA09249A (fr) 1992-06-30
CN1035391C (zh) 1997-07-09
PL161476B1 (pl) 1993-06-30
FI95601C (fi) 1996-02-26
CA2005784A1 (en) 1990-06-19
JP2535080B2 (ja) 1996-09-18
AU624458B2 (en) 1992-06-11
NO895096D0 (no) 1989-12-18
NO895096L (no) 1990-06-20
HUT52562A (en) 1990-07-28
JPH02223589A (ja) 1990-09-05
YU47099B (sh) 1994-12-28
BG90678A (bg) 1993-12-24
FI950946A (fi) 1995-03-01
NZ231831A (en) 1994-10-26

Similar Documents

Publication Publication Date Title
NO176914C (no) Macrolidforbindelser, fremgangsmåte for deres fremstilling, biologisk renset kultur samt preparater inneholdende macrolidforbindelsene
FI954246A (fi) Uusia A83543-yhdisteitä ja menetelmä niiden valmistamiseksi
DK0444964T3 (da) Milbemycinetherderivater, deres fremstilling og deres anthelmentiske anvendelser
WO1993009126B1 (en) New a83543 compounds and process for production thereof
BR0013963A (pt) Macrolìdeos pesticidas
CA2099569A1 (en) New a83543 compounds and process for production thereof
PT74846A (en) Process for preparing compounds of macrolides isolated from the fermentation broth of a strain of streptomyces avermitilis
PT94805A (pt) Processo para a preparacao de um macrolido antiparasitario relacionado com as milbemicinas
AU625416B2 (en) Macrolide compounds
PT89957A (pt) Processo para a preparacao de derivados de milbemicinas uteis como insecticidas e parasiticidas

Legal Events

Date Code Title Description
MK1K Patent expired