ATE150758T1 - Neue a83543 verbindungen und verfahren zu ihrer herstellung - Google Patents

Neue a83543 verbindungen und verfahren zu ihrer herstellung

Info

Publication number
ATE150758T1
ATE150758T1 AT94912774T AT94912774T ATE150758T1 AT E150758 T1 ATE150758 T1 AT E150758T1 AT 94912774 T AT94912774 T AT 94912774T AT 94912774 T AT94912774 T AT 94912774T AT E150758 T1 ATE150758 T1 AT E150758T1
Authority
AT
Austria
Prior art keywords
nrrl
new
components
methods
compounds
Prior art date
Application number
AT94912774T
Other languages
English (en)
Inventor
Jon S Mynderse
Patrick J Baker
James A Mabe
Jan R Turner
Mary L B Huber
Mary C Broughton
Walter M Nakatsukasa
Lawrence Creemer
Herbert A Kirst
James W Martin
Original Assignee
Dowelanco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dowelanco filed Critical Dowelanco
Application granted granted Critical
Publication of ATE150758T1 publication Critical patent/ATE150758T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/22Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom rings with more than six members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/08Systemic pesticides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/10Insect repellent
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dentistry (AREA)
  • Virology (AREA)
  • Pest Control & Pesticides (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Devices That Are Associated With Refrigeration Equipment (AREA)
  • Manufacturing Of Printed Wiring (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT94912774T 1993-03-12 1994-03-11 Neue a83543 verbindungen und verfahren zu ihrer herstellung ATE150758T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3052293A 1993-03-12 1993-03-12

Publications (1)

Publication Number Publication Date
ATE150758T1 true ATE150758T1 (de) 1997-04-15

Family

ID=21854619

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94912774T ATE150758T1 (de) 1993-03-12 1994-03-11 Neue a83543 verbindungen und verfahren zu ihrer herstellung

Country Status (14)

Country Link
US (3) US5840861A (de)
EP (1) EP0688332B1 (de)
JP (1) JP4258575B2 (de)
AT (1) ATE150758T1 (de)
AU (1) AU685107B2 (de)
BR (1) BR9406587A (de)
CA (1) CA2156194C (de)
DE (1) DE69402308T2 (de)
DK (1) DK0688332T3 (de)
ES (1) ES2099604T3 (de)
FI (1) FI107266B (de)
IL (1) IL108979A (de)
TW (1) TW294672B (de)
WO (1) WO1994020518A1 (de)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997000265A1 (en) * 1995-06-14 1997-01-03 Dowelanco Synthetic modification to spinosyn compounds
DE19823397B4 (de) 1998-05-26 2011-07-28 Bayer CropScience AG, 40789 Verwendung von Spinosynen zum Einsatz als Bodeninsektizide
DE19823396A1 (de) * 1998-05-26 1999-12-02 Bayer Ag Synergistische insektizide Mischungen
UA65624C2 (uk) 1998-07-02 2004-04-15 Елі Ліллі Енд Компані Препарат для догляду за волоссям (варіанти) та спосіб боротьби з педикульозним ураженням людини із застосуванням спінозину (варіанти)
US6933318B1 (en) 1999-08-12 2005-08-23 Eli Lilly And Company Topical organic ectoparasiticidal formulations
AU6606400A (en) * 1999-08-12 2001-03-13 Eli Lilly And Company Topical treatment for insect pests in companion animals
US6927210B1 (en) 1999-08-12 2005-08-09 Eli Lilly And Company Ectoparasiticidal aqueous suspension formulations of spinosyns
HUP0202825A2 (en) 1999-08-12 2003-03-28 Lilly Co Eli Oral treatment of companion animals with ectoparasiticidal spinosyns
AU6839300A (en) 1999-08-27 2001-03-26 Bayer Aktiengesellschaft Nucleic acids which code for the enzyme activities of the spinosyn biosynthesis
DE60015161T2 (de) * 1999-09-13 2006-02-02 Dow Agrosciences Llc, Indianapolis Pestizide makrolide
AUPQ441699A0 (en) 1999-12-02 2000-01-06 Eli Lilly And Company Pour-on formulations
AUPQ634300A0 (en) * 2000-03-20 2000-04-15 Eli Lilly And Company Synergistic formulations
US6585990B1 (en) 2001-03-05 2003-07-01 Dow Agrosciences, Llc Compositions and devices using a spinosyn compound for control of insects
JP4554158B2 (ja) * 2001-03-21 2010-09-29 ダウ・アグロサイエンス・エル・エル・シー 有害生物防除性スピノシン誘導体
US20040147766A1 (en) * 2001-03-29 2004-07-29 Marc Stadler Intermediates for producing spinosyns
AR033022A1 (es) 2001-03-30 2003-12-03 Dow Agrosciences Llc Genes biosinteticos para la produccion de insecticida de butenilespinosina
US6727228B2 (en) 2001-04-25 2004-04-27 Johnson & Johnson Consumer Companies, Inc. Pediculicidal and ovacidal treatment compositions and methods for killing head lice and their eggs
DE10135550A1 (de) * 2001-07-20 2003-01-30 Bayer Cropscience Ag Verfahren zum Herstellen von neuen Spinosyn-Derivaten
DK2347654T3 (en) 2001-09-17 2019-04-23 Elanco Us Inc Formulation for the control of lice or ticks in cattle
TWI330183B (de) * 2001-10-22 2010-09-11 Eisai R&D Man Co Ltd
WO2003070908A2 (en) 2002-02-19 2003-08-28 Dow Agrosciences Llc Novel spinosyn-producing polyketide synthases
ES2315740T3 (es) * 2003-11-04 2009-04-01 Intervet International Bv Formulaciones ectoparasiticidas de espinosinas y pesticidas de azol.
EP1849363A1 (de) * 2006-03-09 2007-10-31 Cheminova A/S Synergistische Kombinationen aus Glutaminsäure- und GABA-aktivierten Chloridkanälen agonistischen Pestiziden und mindestens eins von Vitamin E und Niacin
CA2714348C (en) * 2008-02-12 2016-11-08 Dow Agrosciences Llc Pesticidal compositions
CN101560477B (zh) * 2008-04-16 2012-04-25 上海医药工业研究院 发酵多杀菌素产生菌的培养基
US9514283B2 (en) 2008-07-09 2016-12-06 Baxter International Inc. Dialysis system having inventory management including online dextrose mixing
PL2343975T3 (pl) 2008-09-22 2013-02-28 Entarco Sa Przeciwporostowe kompozycje spinozynu, metody ich stosowania i wyroby chronione przed przywieraniem bioorganizmów porostowych
US8268975B2 (en) 2009-04-03 2012-09-18 Dow Agrosciences Llc Demulsification compositions, systems and methods for demulsifying and separating aqueous emulsions
TW201041510A (en) * 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
TW201041507A (en) 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity and methods for preparing same
TW201041508A (en) 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
TW201041509A (en) * 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
WO2010150100A1 (en) 2009-06-24 2010-12-29 Entarco Sa The use of spinosyns and spinosyn compositions against diseases caused by protozoans, viral infections and cancer
MX342130B (es) 2010-05-11 2016-09-14 Dow Agrosciences Llc * Cepas spnk.
US20160184340A1 (en) 2010-12-22 2016-06-30 Christine Kritikou The use of spinosyns and spinosyn compositions as local anesthetics and as antiarrhythmic agents
EP2658377A4 (de) * 2010-12-29 2014-06-18 Dow Agrosciences Llc Verfahren zur kontrolle von insekten
HUE034838T2 (en) 2011-05-03 2018-03-28 Dow Agrosciences Llc Integration of genes into chromosome of saccharopolyspora spinosa
US8741603B2 (en) 2011-05-03 2014-06-03 Agrigenetics Inc. Enhancing spinosyn production with oxygen binding proteins
US9404107B2 (en) 2011-05-03 2016-08-02 Dow Agrosciences Llc Integration of genes into the chromosome of Saccharopolyspora spinosa
US9631195B2 (en) 2011-12-28 2017-04-25 Dow Agrosciences Llc Identification and characterization of the spinactin biosysnthesis gene cluster from spinosyn producing saccharopolyspora spinosa
PL232463B1 (pl) 2012-02-06 2019-06-28 Merial Inc Miękka, nadająca się do żucia kompozycja weterynaryjna do leczenia i/lub zapobiegania infekcji lub inwazji pasożytniczej u zwierzęcia oraz jej zastosowanie
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
AU2012233000B2 (en) * 2012-09-28 2016-01-21 Elanco New Zealand Ectoparasitic Treatment Method and Composition
CA2945766C (en) 2014-04-17 2023-09-26 Merial, Inc. Use of malononitrile compounds for protecting animals from parasites
AR100530A1 (es) 2014-05-19 2016-10-12 Merial Inc Compuestos antihelmínticos
BR122020023385B1 (pt) 2014-06-19 2021-05-25 Merial, Inc composições parasiticidas compreendendo derivados de indol, métodos e usos dos mesmos
WO2016022520A1 (en) 2014-08-05 2016-02-11 Kyung-An Han Composition and methods for modulation of the octopamine receptor and its homologs
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
US10081656B2 (en) 2015-05-20 2018-09-25 Merial, Inc. Anthelmintic depsipeptide compounds
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
WO2018093920A1 (en) 2016-11-16 2018-05-24 Merial, Inc. Anthelmintic depsipeptide compounds
US20200115705A1 (en) 2017-06-06 2020-04-16 Zymergen Inc. A high-throughput (htp) genomic engineering platform for improving saccharopolyspora spinosa
PE20211275A1 (es) 2018-07-09 2021-07-19 Boehringer Ingelheim Animal Health Usa Inc Compuestos heterociclicos antihelminticos
US10730901B2 (en) 2018-07-27 2020-08-04 Aperta Biosciences, Llc Spinosyn formulations for treatment of demodex-induced ocular and facial conditions
EP3883648A1 (de) 2018-11-20 2021-09-29 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylaminoverbindung, zusammensetzungen davon, verfahren zur herstellung und verfahren zur verwendung davon
NZ776819A (en) 2019-01-16 2023-04-28 Boehringer Ingelheim Animal Health Usa Inc Topical compositions comprising a neonicotinoid and a macrocyclic lactone, methods and uses thereof
KR20220002890A (ko) 2019-03-19 2022-01-07 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 구충성 아자-벤조티오펜 및 아자-벤조푸란 화합물
CN110734467B (zh) * 2019-09-10 2021-08-27 北大方正集团有限公司 一种从发酵液中提取纯化多杀霉素的方法
MX2022015038A (es) 2020-05-29 2023-01-04 Boehringer Ingelheim Animal Health Usa Inc Compuestos heterociclicos como anthelminticos.

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2881162A (en) * 1953-11-16 1959-04-07 Abbott Lab Recovery process
US3725385A (en) * 1970-11-02 1973-04-03 Abbott Lab Process for the demethylation of 3-amino macrolides
US4206206A (en) * 1977-03-24 1980-06-03 Kowa Company, Ltd. Antibiotics of the KA-6606 series and pharmaceutical compositions thereof
AU520409B2 (en) * 1977-05-25 1982-01-28 Commonwealth Scientific And Industrial Research Organisation Controlled release composition
US4213966A (en) * 1977-06-02 1980-07-22 E. R. Squibb & Sons, Inc. Method for isolating polyether antibiotics
US4148883A (en) * 1977-08-18 1979-04-10 Pfizer Inc. Antibiotics produced by new species of nocardia
US4224314A (en) * 1979-03-02 1980-09-23 Pfizer Inc. Antibiotics produced by species of Nocardia
JPS5943929B2 (ja) * 1979-08-13 1984-10-25 サッポロビール株式会社 多糖体rbs物質,その製法およびそれを有効成分とする抗腫瘍性剤
US4273920A (en) * 1979-09-12 1981-06-16 Eli Lilly And Company Polymerization process and product
NZ194901A (en) * 1979-09-12 1983-07-15 Lilly Co Eli Device for oral delivery of drug to reticulorumen of ruminant
US4321329A (en) * 1979-10-02 1982-03-23 The Upjohn Company Saccharopolyspora culture
US4251511A (en) * 1979-10-02 1981-02-17 The Upjohn Company Antibiotic and fermentation process of preparing
US4293651A (en) * 1979-10-02 1981-10-06 The Upjohn Company Process for producing antibiotic using saccharopolyspora
EP0043197A1 (de) * 1980-07-02 1982-01-06 Beecham Group Plc Beta-Lactam-Antibiotikum, Herstellung und Verwendung
DE3162169D1 (en) * 1980-07-15 1984-03-15 Kowa Co Process for production of antibiotics, and novel antibiotics produced thereby
US4448970A (en) * 1981-02-19 1984-05-15 The Upjohn Company Nargenicin derivatives
IT1195299B (it) * 1981-11-27 1988-10-12 Pierrel Spa Procedimento chimico di sintesi per la preparazione di antibiotici macrolidici
CH656622A5 (de) * 1981-12-08 1986-07-15 Toyo Jozo Kk Aminoglycosid-antibiotika saccharocine und deren herstellung.
JPS58189114A (ja) * 1982-04-30 1983-11-04 Ss Pharmaceut Co Ltd 抗潰瘍剤
US4508647A (en) * 1982-07-26 1985-04-02 Bristol-Myers Company Antitumor antibiotics BBM-2040A and BBM-2040B
IT1194181B (it) * 1983-03-30 1988-09-14 Erba Farmitalia Procedimento migliorato per la purificazione della tilosina
US4530835A (en) * 1983-07-08 1985-07-23 Warner-Lambert Company CL-1577 Antibiotic compounds and their production
US4560509A (en) * 1983-11-16 1985-12-24 Eli Lilly And Company Antibiotic A39079 factor S-1
JPS625990A (ja) * 1985-06-20 1987-01-12 Sumitomo Chem Co Ltd 抗生物質およびその製造方法
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
JPS62226925A (ja) * 1986-03-28 1987-10-05 Ss Pharmaceut Co Ltd 抗マイコプラズマ剤
US4831016A (en) * 1986-10-31 1989-05-16 Merck & Co., Inc. Reduced avermectin derivatives
US5003056A (en) * 1987-12-24 1991-03-26 Nippon Kayaku Kabushiki Kaisha Antibiotic NK86-0279, process for production of the same and application of the same
US5362634A (en) * 1989-10-30 1994-11-08 Dowelanco Process for producing A83543 compounds
PE5591A1 (es) * 1988-12-19 1991-02-15 Lilly Co Eli Un nuevo grupo de compuestos de macrolida
US5028536A (en) * 1989-03-15 1991-07-02 Bristol-Myers Squibb Company Antitumor antibiotic BMY-41339
WO1991006552A1 (en) * 1989-10-30 1991-05-16 Eli Lilly And Company A83543 recovery process
US5202242A (en) * 1991-11-08 1993-04-13 Dowelanco A83543 compounds and processes for production thereof
CN1073483A (zh) * 1991-11-08 1993-06-23 道伊兰科公司 一种发酵杀虫剂化合物及其制备方法
US5227295A (en) * 1991-11-08 1993-07-13 Dowelanco Process for isolating A83543 and its components

Also Published As

Publication number Publication date
DE69402308D1 (de) 1997-04-30
DK0688332T3 (da) 1997-10-13
CA2156194C (en) 2008-01-08
TW294672B (de) 1997-01-01
FI954246L (fi) 1995-09-11
ES2099604T3 (es) 1997-05-16
AU6518794A (en) 1994-09-26
WO1994020518A1 (en) 1994-09-15
US5670486A (en) 1997-09-23
IL108979A0 (en) 1994-06-24
DE69402308T2 (de) 1997-10-23
US5670364A (en) 1997-09-23
CA2156194A1 (en) 1994-09-15
IL108979A (en) 1999-09-22
JPH08507533A (ja) 1996-08-13
AU685107B2 (en) 1998-01-15
FI107266B (fi) 2001-06-29
US5840861A (en) 1998-11-24
EP0688332A1 (de) 1995-12-27
JP4258575B2 (ja) 2009-04-30
BR9406587A (pt) 1996-01-02
FI954246A0 (fi) 1995-09-11
EP0688332B1 (de) 1997-03-26

Similar Documents

Publication Publication Date Title
ATE150758T1 (de) Neue a83543 verbindungen und verfahren zu ihrer herstellung
CA2099569A1 (en) New a83543 compounds and process for production thereof
AU4689189A (en) Macrolide compounds
RU93058364A (ru) Новые соединения а83543 и способ их получения
BG44205A3 (en) Method for preparing of antibiotic s541
PT78784B (de) Anthracyclin-derivate ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als cytostatika
DE3888587D1 (de) AB-006-Antibiotika und Verfahren zu deren Herstellung.
IE780638L (en) B-lactam antibiotic.
FI901237A0 (fi) Ws7622a-, b-, c- och d-substanser, deras derivat, foerfarande foer deras framstaellning och deras anvaendning.
DE68918071D1 (de) Antibiotikum A80915 und Verfahren zu seiner Herstellung.
IL90575A0 (en) Ab-011 antibiotics,their production and compositions containing them
JPS5462392A (en) Preparation of antibiotic substance, sisomicin

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification