NO174256C - Analogifremgangsmåte ved fremstilling av terapeutisk aktive kinuklidinderivater - Google Patents

Analogifremgangsmåte ved fremstilling av terapeutisk aktive kinuklidinderivater

Info

Publication number
NO174256C
NO174256C NO904523A NO904523A NO174256C NO 174256 C NO174256 C NO 174256C NO 904523 A NO904523 A NO 904523A NO 904523 A NO904523 A NO 904523A NO 174256 C NO174256 C NO 174256C
Authority
NO
Norway
Prior art keywords
therapeutically active
analogous method
quinuclidine derivatives
preparing therapeutically
halo
Prior art date
Application number
NO904523A
Other languages
English (en)
Other versions
NO174256B (no
NO904523D0 (no
NO904523L (no
Inventor
Peter Edward Cross
Alan Stobie
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO904523D0 publication Critical patent/NO904523D0/no
Publication of NO904523L publication Critical patent/NO904523L/no
Publication of NO174256B publication Critical patent/NO174256B/no
Publication of NO174256C publication Critical patent/NO174256C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Feeding And Guiding Record Carriers (AREA)
  • Glass Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO904523A 1989-10-19 1990-10-18 Analogifremgangsmåte ved fremstilling av terapeutisk aktive kinuklidinderivater NO174256C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898923590A GB8923590D0 (en) 1989-10-19 1989-10-19 Antimuscarinic bronchodilators

Publications (4)

Publication Number Publication Date
NO904523D0 NO904523D0 (no) 1990-10-18
NO904523L NO904523L (no) 1991-04-22
NO174256B NO174256B (no) 1993-12-27
NO174256C true NO174256C (no) 1994-04-06

Family

ID=10664848

Family Applications (1)

Application Number Title Priority Date Filing Date
NO904523A NO174256C (no) 1989-10-19 1990-10-18 Analogifremgangsmåte ved fremstilling av terapeutisk aktive kinuklidinderivater

Country Status (19)

Country Link
US (1) US5171744A (no)
EP (1) EP0424021B1 (no)
JP (1) JPH06780B2 (no)
KR (1) KR930004845B1 (no)
CN (1) CN1022488C (no)
AT (1) ATE102198T1 (no)
AU (1) AU616362B2 (no)
CA (1) CA2027896A1 (no)
DE (1) DE69007009T2 (no)
FI (1) FI905147A0 (no)
GB (1) GB8923590D0 (no)
HU (1) HU206345B (no)
NO (1) NO174256C (no)
NZ (1) NZ235750A (no)
PL (1) PL287365A1 (no)
PT (1) PT95610A (no)
RU (1) RU2005721C1 (no)
YU (1) YU197290A (no)
ZA (1) ZA908343B (no)

Families Citing this family (77)

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ATE205844T1 (de) * 1990-09-06 2001-10-15 Pfizer Anti-muscarin bronchodilatoren
GB9119705D0 (en) * 1991-09-14 1991-10-30 Pfizer Ltd Therapeutic compounds
US5340826A (en) * 1993-02-04 1994-08-23 Pfizer Inc. Pharmaceutical agents for treatment of urinary incontinence
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KR101084787B1 (ko) 2007-01-10 2011-11-21 아이알엠 엘엘씨 채널 활성화 프로테아제 억제제로서의 화합물 및 조성물
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US8268834B2 (en) 2008-03-19 2012-09-18 Novartis Ag Pyrazine derivatives that inhibit phosphatidylinositol 3-kinase enzyme
JP2011522860A (ja) 2008-06-10 2011-08-04 ノバルティス アーゲー 上皮性ナトリウムチャネルブロッカーとしてのピラジン誘導体
EP2206712A1 (en) 2008-12-23 2010-07-14 CHIESI FARMACEUTICI S.p.A. "Alkaloid aminoester derivatives and medicinal composition thereof"
ES2396023T3 (es) 2009-01-29 2013-02-18 Novartis Ag Bencimidazoles sustituidos para el tratamiento de astrocitomas
US8389526B2 (en) 2009-08-07 2013-03-05 Novartis Ag 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
AU2010283806A1 (en) 2009-08-12 2012-03-01 Novartis Ag Heterocyclic hydrazone compounds and their uses to treat cancer and inflammation
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BR112012032333A2 (pt) * 2010-06-22 2016-11-08 Chiesi Farma Spa composto, uso de um composto, composição farmacêutica, combinação de um composto e dispositivo
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WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
US8372845B2 (en) 2010-09-17 2013-02-12 Novartis Ag Pyrazine derivatives as enac blockers
US20130324526A1 (en) 2011-02-10 2013-12-05 Novartis Ag [1,2,4] triazolo [4,3-b] pyridazine compounds as inhibitors of the c-met tyrosine kinase
WO2012116237A2 (en) 2011-02-23 2012-08-30 Intellikine, Llc Heterocyclic compounds and uses thereof
KR20140014184A (ko) 2011-02-25 2014-02-05 아이알엠 엘엘씨 Trk 억제제로서의 화합물 및 조성물
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UY34305A (es) 2011-09-01 2013-04-30 Novartis Ag Derivados de heterociclos bicíclicos para el tratamiento de la hipertensión arterial pulmonar
EA026655B1 (ru) 2011-09-15 2017-05-31 Новартис Аг 6-ЗАМЕЩЕННЫЕ 3-(ХИНОЛИН-6-ИЛТИО)[1,2,4]ТРИАЗОЛО[4,3-a]ПИРИДИНЫ В КАЧЕСТВЕ ИНГИБИТОРОВ c-MET ТИРОЗИНКИНАЗЫ
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WO2013038386A1 (en) 2011-09-16 2013-03-21 Novartis Ag Heterocyclic compounds for the treatment of cystic fibrosis
JP6165733B2 (ja) 2011-09-16 2017-07-19 ノバルティス アーゲー Ｎ−置換ヘテロシクリルカルボキサミド類
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WO2013038381A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine/pyrazine amide derivatives
WO2013078440A2 (en) 2011-11-23 2013-05-30 Intellikine, Llc Enhanced treatment regimens using mtor inhibitors
US8809340B2 (en) 2012-03-19 2014-08-19 Novartis Ag Crystalline form
EP2834246B1 (en) 2012-04-03 2021-07-28 Novartis AG Combination products with tyrosine kinase inhibitors and their use
US9073921B2 (en) 2013-03-01 2015-07-07 Novartis Ag Salt forms of bicyclic heterocyclic derivatives
EP2968340A4 (en) 2013-03-15 2016-08-10 Intellikine Llc COMBINING KINASE INHIBITORS AND USES THEREOF
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JP6454727B2 (ja) 2014-04-24 2019-01-16 ノバルティス アーゲー ホスファチジルイノシトール３−キナーゼ阻害薬としてのアミノピリジン誘導体
EA033571B1 (ru) 2014-04-24 2019-11-06 Novartis Ag Производные пиразина в качестве ингибиторов фосфатидилинозитол 3-киназы
KR20160141855A (ko) 2014-04-24 2016-12-09 노파르티스 아게 포스파티딜이노시톨 3-키나제 억제제로서의 아미노 피라진 유도체
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US4843074A (en) * 1988-05-17 1989-06-27 Marion Laboratories, Inc. 1-azabicyclo[2.2.2]octan-3-yl 2-aryl-3-azacyclo-2-hydroxypropionates and their quaternary salts
IT1228288B (it) * 1989-01-09 1991-06-07 Zambon Spa Composti ad attivita' antiserotoninica

Also Published As

Publication number Publication date
KR930004845B1 (ko) 1993-06-09
CN1022488C (zh) 1993-10-20
RU2005721C1 (ru) 1994-01-15
NO174256B (no) 1993-12-27
PT95610A (pt) 1991-09-13
NO904523D0 (no) 1990-10-18
AU6472690A (en) 1991-07-25
US5171744A (en) 1992-12-15
GB8923590D0 (en) 1989-12-06
FI905147A0 (fi) 1990-10-18
HU206345B (en) 1992-10-28
JPH06780B2 (ja) 1994-01-05
KR910007924A (ko) 1991-05-30
HUT56365A (en) 1991-08-28
CA2027896A1 (en) 1991-04-20
NO904523L (no) 1991-04-22
PL287365A1 (en) 1991-06-03
DE69007009T2 (de) 1994-06-09
YU197290A (sh) 1993-10-20
NZ235750A (en) 1992-03-26
CN1051041A (zh) 1991-05-01
HU906495D0 (en) 1991-04-29
ATE102198T1 (de) 1994-03-15
DE69007009D1 (de) 1994-04-07
EP0424021A1 (en) 1991-04-24
ZA908343B (en) 1992-06-24
JPH03133980A (ja) 1991-06-07
EP0424021B1 (en) 1994-03-02
AU616362B2 (en) 1991-10-24

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