ZA908343B - Antimuscarinic bronchodilators - Google Patents

Antimuscarinic bronchodilators

Info

Publication number
ZA908343B
ZA908343B ZA908343A ZA908343A ZA908343B ZA 908343 B ZA908343 B ZA 908343B ZA 908343 A ZA908343 A ZA 908343A ZA 908343 A ZA908343 A ZA 908343A ZA 908343 B ZA908343 B ZA 908343B
Authority
ZA
South Africa
Prior art keywords
halo
substituents
alkoxy
hydroxy
optionally substituted
Prior art date
Application number
ZA908343A
Other languages
English (en)
Inventor
Peter Edward Cross
Edward Cross Peter
Alan Stobie
Stobie Alan
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA908343B publication Critical patent/ZA908343B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Glass Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Feeding And Guiding Record Carriers (AREA)
ZA908343A 1989-10-19 1990-10-18 Antimuscarinic bronchodilators ZA908343B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898923590A GB8923590D0 (en) 1989-10-19 1989-10-19 Antimuscarinic bronchodilators

Publications (1)

Publication Number Publication Date
ZA908343B true ZA908343B (en) 1992-06-24

Family

ID=10664848

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA908343A ZA908343B (en) 1989-10-19 1990-10-18 Antimuscarinic bronchodilators

Country Status (19)

Country Link
US (1) US5171744A (xx)
EP (1) EP0424021B1 (xx)
JP (1) JPH06780B2 (xx)
KR (1) KR930004845B1 (xx)
CN (1) CN1022488C (xx)
AT (1) ATE102198T1 (xx)
AU (1) AU616362B2 (xx)
CA (1) CA2027896A1 (xx)
DE (1) DE69007009T2 (xx)
FI (1) FI905147A0 (xx)
GB (1) GB8923590D0 (xx)
HU (1) HU206345B (xx)
NO (1) NO174256C (xx)
NZ (1) NZ235750A (xx)
PL (1) PL287365A1 (xx)
PT (1) PT95610A (xx)
RU (1) RU2005721C1 (xx)
YU (1) YU197290A (xx)
ZA (1) ZA908343B (xx)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
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EP0500864B1 (en) * 1990-09-06 2001-09-19 Pfizer Limited Antimuscarinic bronchodilators
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CA2672446A1 (en) * 2006-12-19 2008-06-26 Astrazeneca Ab Quinuclidinol derivatives as muscarinic receptor antagonists
AU2007342223B2 (en) 2007-01-10 2011-02-24 Irm Llc Compounds and compositions as channel activating protease inhibitors
ES2361595T3 (es) 2007-05-07 2011-06-20 Novartis Ag Compuestos orgánicos.
BRPI0812000A2 (pt) * 2007-05-30 2014-11-18 Microdose Therapeutx Inc Métodos e composições para administração de oxibutinina
US8415390B2 (en) 2008-05-30 2013-04-09 Microdose Therapeutx, Inc. Methods and compositions for administration of oxybutynin
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TW201031406A (en) 2009-01-29 2010-09-01 Novartis Ag Substituted benzimidazoles for the treatment of astrocytomas
US8389526B2 (en) 2009-08-07 2013-03-05 Novartis Ag 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
CA2770873A1 (en) 2009-08-12 2011-02-17 Novartis Ag Heterocyclic hydrazone compounds and their uses to treat cancer and inflammation
IN2012DN01961A (xx) 2009-08-17 2015-08-21 Intellikine Llc
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WO2011050325A1 (en) 2009-10-22 2011-04-28 Vertex Pharmaceuticals Incorporated Compositions for treatment of cystic fibrosis and other chronic diseases
US8247436B2 (en) 2010-03-19 2012-08-21 Novartis Ag Pyridine and pyrazine derivative for the treatment of CF
RU2569846C2 (ru) * 2010-06-22 2015-11-27 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Алкалоидные производные сложных аминоэфиров и включающие их лекарственные композиции
UY33597A (es) 2010-09-09 2012-04-30 Irm Llc Compuestos y composiciones como inhibidores de la trk
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
US8372845B2 (en) 2010-09-17 2013-02-12 Novartis Ag Pyrazine derivatives as enac blockers
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UY34305A (es) 2011-09-01 2013-04-30 Novartis Ag Derivados de heterociclos bicíclicos para el tratamiento de la hipertensión arterial pulmonar
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WO2013038381A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine/pyrazine amide derivatives
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US9174994B2 (en) 2011-11-23 2015-11-03 Intellikine, Llc Enhanced treatment regimens using mTor inhibitors
US8809340B2 (en) 2012-03-19 2014-08-19 Novartis Ag Crystalline form
RU2660354C2 (ru) 2012-04-03 2018-07-05 Новартис Аг Комбинированные продукты, содержащие ингибиторы тирозинкиназ, и их применение
US9073921B2 (en) 2013-03-01 2015-07-07 Novartis Ag Salt forms of bicyclic heterocyclic derivatives
WO2014151147A1 (en) 2013-03-15 2014-09-25 Intellikine, Llc Combination of kinase inhibitors and uses thereof
WO2015084804A1 (en) 2013-12-03 2015-06-11 Novartis Ag Combination of mdm2 inhibitor and braf inhibitor and their use
KR20160141855A (ko) 2014-04-24 2016-12-09 노파르티스 아게 포스파티딜이노시톨 3-키나제 억제제로서의 아미노 피라진 유도체
PT3134396T (pt) 2014-04-24 2019-12-16 Novartis Ag Derivados de amino piridina como inibidores da fosfatidilinositol 3-quinase
PL3134395T3 (pl) 2014-04-24 2018-07-31 Novartis Ag Pochodne pirazyny jako inhibitory 3-kinazy fosfatydyloinozytolu
WO2016011658A1 (en) 2014-07-25 2016-01-28 Novartis Ag Combination therapy
CN107207510B (zh) 2014-07-31 2019-11-29 诺华股份有限公司 联合疗法
CN113891744A (zh) 2019-06-10 2022-01-04 诺华股份有限公司 用于治疗cf、copd和支气管扩张的吡啶和吡嗪衍生物
KR20220052934A (ko) 2019-08-28 2022-04-28 노파르티스 아게 치환 1,3-페닐 헤테로아릴 유도체 및 질환 치료에서의 이의 용도
TW202140550A (zh) 2020-01-29 2021-11-01 瑞士商諾華公司 使用抗ｔｓｌｐ抗體治療炎性或阻塞性氣道疾病之方法

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IT1228288B (it) * 1989-01-09 1991-06-07 Zambon Spa Composti ad attivita' antiserotoninica

Also Published As

Publication number Publication date
NO174256B (no) 1993-12-27
JPH06780B2 (ja) 1994-01-05
KR910007924A (ko) 1991-05-30
DE69007009T2 (de) 1994-06-09
CN1022488C (zh) 1993-10-20
EP0424021B1 (en) 1994-03-02
EP0424021A1 (en) 1991-04-24
NO904523D0 (no) 1990-10-18
CA2027896A1 (en) 1991-04-20
RU2005721C1 (ru) 1994-01-15
GB8923590D0 (en) 1989-12-06
NO904523L (no) 1991-04-22
AU616362B2 (en) 1991-10-24
PT95610A (pt) 1991-09-13
YU197290A (sh) 1993-10-20
NO174256C (no) 1994-04-06
DE69007009D1 (de) 1994-04-07
NZ235750A (en) 1992-03-26
JPH03133980A (ja) 1991-06-07
HU206345B (en) 1992-10-28
KR930004845B1 (ko) 1993-06-09
ATE102198T1 (de) 1994-03-15
AU6472690A (en) 1991-07-25
CN1051041A (zh) 1991-05-01
PL287365A1 (en) 1991-06-03
US5171744A (en) 1992-12-15
FI905147A0 (fi) 1990-10-18
HUT56365A (en) 1991-08-28
HU906495D0 (en) 1991-04-29

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