NL8002567A - Fenylethylaminederivaten, werkwijzen ter bereiding ervan, preparaten die de nieuwe derivaten bevatten, alsmede werkwijzen ter bereiding daarvan. - Google Patents

Fenylethylaminederivaten, werkwijzen ter bereiding ervan, preparaten die de nieuwe derivaten bevatten, alsmede werkwijzen ter bereiding daarvan. Download PDF

Info

Publication number
NL8002567A
NL8002567A NL8002567A NL8002567A NL8002567A NL 8002567 A NL8002567 A NL 8002567A NL 8002567 A NL8002567 A NL 8002567A NL 8002567 A NL8002567 A NL 8002567A NL 8002567 A NL8002567 A NL 8002567A
Authority
NL
Netherlands
Prior art keywords
group
carbon atoms
formula
phenoxy
alkyl group
Prior art date
Application number
NL8002567A
Other languages
English (en)
Dutch (nl)
Original Assignee
Continental Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Continental Pharma filed Critical Continental Pharma
Publication of NL8002567A publication Critical patent/NL8002567A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
NL8002567A 1979-05-04 1980-05-02 Fenylethylaminederivaten, werkwijzen ter bereiding ervan, preparaten die de nieuwe derivaten bevatten, alsmede werkwijzen ter bereiding daarvan. NL8002567A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU81225 1979-05-04
LU81225 1979-05-04

Publications (1)

Publication Number Publication Date
NL8002567A true NL8002567A (nl) 1980-11-06

Family

ID=19729148

Family Applications (2)

Application Number Title Priority Date Filing Date
NL8002567A NL8002567A (nl) 1979-05-04 1980-05-02 Fenylethylaminederivaten, werkwijzen ter bereiding ervan, preparaten die de nieuwe derivaten bevatten, alsmede werkwijzen ter bereiding daarvan.
NL8002568A NL8002568A (nl) 1979-05-04 1980-05-02 Benzimidazoolderivaten, werkwijzen ter bereiding ervan, farmaceutische preparaten, die de benzimida- zoolderivaten bevatten, alsmede werkwijzen ter bereiding van farmaceutische preparaten.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NL8002568A NL8002568A (nl) 1979-05-04 1980-05-02 Benzimidazoolderivaten, werkwijzen ter bereiding ervan, farmaceutische preparaten, die de benzimida- zoolderivaten bevatten, alsmede werkwijzen ter bereiding van farmaceutische preparaten.

Country Status (22)

Country Link
US (1) US4338330A (el)
JP (2) JPS6033424B2 (el)
AT (2) AT376418B (el)
AU (2) AU542596B2 (el)
BE (2) BE883069A (el)
CA (1) CA1146563A (el)
CH (2) CH644599A5 (el)
DE (2) DE3016828A1 (el)
DK (2) DK187980A (el)
ES (2) ES491143A0 (el)
FI (2) FI801428A (el)
FR (2) FR2455572B1 (el)
GB (2) GB2055360B (el)
GR (2) GR68535B (el)
IE (1) IE50218B1 (el)
IL (2) IL59973A (el)
IT (2) IT1150018B (el)
NL (2) NL8002567A (el)
NO (2) NO150916C (el)
PT (2) PT71174A (el)
SE (2) SE8003278L (el)
ZA (2) ZA802694B (el)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1156661A (en) * 1980-02-25 1983-11-08 Hoffmann-La Roche Limited Phenoxy-aminopropanol derivatives
JPS582343A (ja) * 1981-06-30 1983-01-07 Osaka Soda Co Ltd 耐窒素酸化物性に優れた加硫性ゴム組成物
GB8310556D0 (en) * 1983-04-19 1983-05-25 Beecham Group Plc Compounds
US4550119A (en) * 1983-05-23 1985-10-29 Warner-Lambert Company 2,4-Dihydro-5-[(substituted)phenyl]-4,4-disubstituted-3H-pyrazol-3-ones
US5104892A (en) * 1989-12-11 1992-04-14 American Home Products Corporation Substituted benzimidazole derivatives possessing Class III antiarrhythmic activity
US5541204A (en) * 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
JP2005520858A (ja) 2002-03-20 2005-07-14 メタボレックス， インコーポレイテッド 置換フェニル酢酸
US7351719B2 (en) 2002-10-31 2008-04-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds
US7199259B2 (en) * 2003-06-20 2007-04-03 Metabolex, Inc. Resolution of α-(phenoxy)phenylacetic acid derivatives
RU2006145872A (ru) * 2004-05-25 2008-06-27 Метаболекс, Инк. (Us) Замещенные триазолы в качестве модуляторов ppar и способы их получения
EP1749000A4 (en) * 2004-05-25 2009-12-30 Metabolex Inc BICYCLIC SUBSTITUTED TRIAZOLE AS PPAR MODULATORS AND METHOD FOR THE PRODUCTION THEREOF
US7714131B2 (en) * 2005-09-23 2010-05-11 Metabolex, Inc. Process for the stereoselective preparation of (−)-halofenate and derivatives thereof
EP2727911B1 (en) * 2012-10-31 2016-12-21 Medizinische Hochschule Hannover Novel means and methods for treating malaria and other parasitic disorders

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1157556A (en) * 1966-06-09 1969-07-09 Egyt Gyogyszervegyeszeti Gyar Novel Benzazole Derivatives and the Preparation thereof
FR1570892A (el) 1968-06-18 1969-06-13
US3574218A (en) * 1969-08-11 1971-04-06 Egyt Gyogyszervegyeszeti Gyar 2-aryl- or aralkyl-substituted benzazole derivatives
JPS5231858B1 (el) * 1969-12-17 1977-08-17
CH624395A5 (el) 1976-01-08 1981-07-31 Ciba Geigy Ag
DE2609645A1 (de) 1976-03-09 1977-09-15 Boehringer Sohn Ingelheim Aminoalkylheterocyclen
DE2640730C2 (de) * 1976-09-10 1983-08-25 Hoechst Ag, 6230 Frankfurt Benzoxazolyloxy- und Benzothiazolyloxy-phenoxy-Verbindungen und diese enthaltende herbizide Mittel
DE2644833A1 (de) * 1976-10-05 1978-04-20 Boehringer Sohn Ingelheim Neue 1-aryloxy-2-hydroxy-3-alkylenaminopropane und verfahren zu ihrer herstellung
DE2737630A1 (de) 1977-08-20 1979-03-01 Boehringer Mannheim Gmbh Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2801953A1 (de) 1978-01-18 1979-07-19 Boehringer Mannheim Gmbh 4-hydroxy-2-benzimidazolinon-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
DE2801980A1 (de) 1978-01-18 1979-07-19 Boehringer Mannheim Gmbh 4-hydroxy-2-benzimidazolin-thion- derivate, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
EP0003758A1 (de) 1978-02-09 1979-09-05 Ciba-Geigy Ag Verätherte Hydroxy-benzodiheterocyclen und ihre Säureadditionssalze, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate
DE2905877A1 (de) 1979-02-16 1980-08-28 Boehringer Mannheim Gmbh Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2905876A1 (de) 1979-02-16 1980-08-28 Boehringer Mannheim Gmbh Neue piperidinopropylderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
SE8003277L (sv) 1980-11-05
ZA802695B (en) 1981-08-26
FR2455572B1 (fr) 1986-07-25
IT8021779A0 (it) 1980-05-02
FI801429A (fi) 1980-11-05
CH645090A5 (fr) 1984-09-14
GB2055091A (en) 1981-02-25
ATA238680A (de) 1984-04-15
GB2055360B (en) 1983-07-06
GR68535B (el) 1982-01-18
IT1159060B (it) 1987-02-25
IL59974A0 (en) 1980-07-31
IE800918L (en) 1980-11-04
AU5809680A (en) 1980-11-06
FR2455572A1 (fr) 1980-11-28
CH644599A5 (fr) 1984-08-15
ATA238780A (de) 1984-03-15
BE883068A (fr) 1980-08-18
AU537573B2 (en) 1984-07-05
DE3016828A1 (de) 1980-11-13
AU542596B2 (en) 1985-02-28
NL8002568A (nl) 1980-11-06
JPS6033424B2 (ja) 1985-08-02
AT376210B (de) 1984-10-25
IT8021780A0 (it) 1980-05-02
SE8003278L (sv) 1980-11-05
GB2055091B (en) 1983-11-09
DK187880A (da) 1980-11-05
ES8103729A1 (es) 1981-03-16
JPS5663946A (en) 1981-05-30
PT71174A (fr) 1980-05-01
IT8021780A1 (it) 1981-11-02
IE50218B1 (en) 1986-03-05
NO150916B (no) 1984-10-01
US4338330A (en) 1982-07-06
NO801285L (no) 1980-11-05
IT1150018B (it) 1986-12-10
IL59973A0 (en) 1980-07-31
NO801286L (no) 1980-11-05
JPS565465A (en) 1981-01-20
ES8104245A1 (es) 1981-04-16
CA1146563A (en) 1983-05-17
NO150916C (no) 1985-01-16
ZA802694B (en) 1981-08-26
ES491143A0 (es) 1981-04-16
FR2455587A1 (fr) 1980-11-28
AU5809580A (en) 1980-11-06
BE883069A (fr) 1980-08-18
ES491142A0 (es) 1981-03-16
FR2455587B1 (el) 1983-06-24
FI801428A (fi) 1980-11-05
GB2055360A (en) 1981-03-04
IT8021779A1 (it) 1981-11-02
GR68536B (el) 1982-01-18
IL59973A (en) 1985-03-31
DE3016827A1 (de) 1980-11-20
AT376418B (de) 1984-11-26
PT71175A (fr) 1980-05-01
DK187980A (da) 1980-11-05

Similar Documents

Publication Publication Date Title
NL8002567A (nl) Fenylethylaminederivaten, werkwijzen ter bereiding ervan, preparaten die de nieuwe derivaten bevatten, alsmede werkwijzen ter bereiding daarvan.
US4081447A (en) 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof
JP2637737B2 (ja) 新規な薬剤
JPS62167752A (ja) フエニルアセトニトリル誘導体その医薬組成物および哺乳動物におけるカルシウムイオンきつ抗作用または抗高圧作用促進方法
NL8003601A (nl) Amino-etheroxyden, werkwijze voor de bereiding hiervan en de toepassing als geneesmiddel.
JPS6059914B2 (ja) フエノ（アルコ）キシ−置換されたオキシランカルボン酸、その製法、その使用及びこれを含有する医薬品
CH617697A5 (el)
CH542177A (fr) Procédé de préparation d'amino-alcools et de leurs sels
EP0028959B1 (fr) Dérivés de la 5,8,13,13a-tétrahydro-6H-dibenzo (a,g) quinolizine, procédé d'obtention et compositions pharmaceutiques les contenant
CA1120945A (en) Esters of 1,1,2-triphenylalkene derivatives
DK159425B (da) 5-acyl-3-cyano-2-(1h)-pyridinoner eller syreadditionssalte deraf
Yamato et al. Synthesis and structure-activity relationship of spiro [isochromanpiperidine] analogs for inhibition of histamine release. 1
US4515814A (en) 3-Phenoxypropan-2-ol derivatives for treating glaucoma
US4490392A (en) Benzylalcohol derivative and process for preparing
BE854655A (fr) 9-hydroxyhexahydrobenzo (c) quinoleines et intermediaires de synthese
KR840001840B1 (ko) 1-아릴옥시-3-알킬아미노-2-프로판올류의 제조방법
Brown et al. Chiral synthesis of 3-substituted morpholines via serine enantiomers and reductions of 5-oxomorpholine-3-carboxylates
CH652119A5 (fr) Derives de l'acide guanidinocyclohexanecarboxylique et leur procede de fabrication.
US3969363A (en) Derivatives of 1-phenoxy-3-amino-propan-2-ol and process for their production
JPS584026B2 (ja) ピラジンユウドウタイ オヨビ セイホウ
EP0173634A1 (fr) Nouveaux dérivés d'(arylpipérazinyléthylaminoéthoxy)-4 phénol, leur méthode de préparation et leur application thérapeutique
JPS6037096B2 (ja) ピリジン誘導体の製法
US4201790A (en) Benzophenone derivatives
FR2567754A1 (fr) Application therapeutique d'aminomethylene-2 indanediones-1,3 substituees sur l'azote
KR840002005B1 (ko) 피페라진 유도체의 제조방법

Legal Events

Date Code Title Description
A1A A request for search or an international-type search has been filed
BB A search report has been drawn up
A85 Still pending on 85-01-01
CNR Transfer of rights (patent application after its laying open for public inspection)

Free format text: CONTINENTAL PHARMA, INC.

BC A request for examination has been filed
BV The patent application has lapsed