IT1150018B - Derivati del benzimmidazolo,loro preparazione e loro impiego e anche composizioni contenenti questi derivati - Google Patents

Derivati del benzimmidazolo,loro preparazione e loro impiego e anche composizioni contenenti questi derivati

Info

Publication number
IT1150018B
IT1150018B IT8021779A IT2177980A IT1150018B IT 1150018 B IT1150018 B IT 1150018B IT 8021779 A IT8021779 A IT 8021779A IT 2177980 A IT2177980 A IT 2177980A IT 1150018 B IT1150018 B IT 1150018B
Authority
IT
Italy
Prior art keywords
derivatives
benzimmidazole
preparation
compositions containing
compositions
Prior art date
Application number
IT8021779A
Other languages
English (en)
Other versions
IT8021779A0 (it
IT8021779A1 (it
Inventor
Claude Gillet
Joseph Roba
Georges Lambelin
Dorsser William Van
Michel Snyers
Original Assignee
Continental Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Continental Pharma filed Critical Continental Pharma
Publication of IT8021779A0 publication Critical patent/IT8021779A0/it
Publication of IT8021779A1 publication Critical patent/IT8021779A1/it
Application granted granted Critical
Publication of IT1150018B publication Critical patent/IT1150018B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
IT8021779A 1979-05-04 1980-05-02 Derivati del benzimmidazolo,loro preparazione e loro impiego e anche composizioni contenenti questi derivati IT1150018B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU81225 1979-05-04

Publications (3)

Publication Number Publication Date
IT8021779A0 IT8021779A0 (it) 1980-05-02
IT8021779A1 IT8021779A1 (it) 1981-11-02
IT1150018B true IT1150018B (it) 1986-12-10

Family

ID=19729148

Family Applications (2)

Application Number Title Priority Date Filing Date
IT8021779A IT1150018B (it) 1979-05-04 1980-05-02 Derivati del benzimmidazolo,loro preparazione e loro impiego e anche composizioni contenenti questi derivati
IT8021780A IT1159060B (it) 1979-05-04 1980-05-02 Derivati della feniletilammina,loro preparazione e loro impiego e anche composizioni che contengono guesti derivati

Family Applications After (1)

Application Number Title Priority Date Filing Date
IT8021780A IT1159060B (it) 1979-05-04 1980-05-02 Derivati della feniletilammina,loro preparazione e loro impiego e anche composizioni che contengono guesti derivati

Country Status (22)

Country Link
US (1) US4338330A (it)
JP (2) JPS6033424B2 (it)
AT (2) AT376210B (it)
AU (2) AU542596B2 (it)
BE (2) BE883069A (it)
CA (1) CA1146563A (it)
CH (2) CH644599A5 (it)
DE (2) DE3016828A1 (it)
DK (2) DK187880A (it)
ES (2) ES8103729A1 (it)
FI (2) FI801428A (it)
FR (2) FR2455572B1 (it)
GB (2) GB2055091B (it)
GR (2) GR68535B (it)
IE (1) IE50218B1 (it)
IL (2) IL59973A (it)
IT (2) IT1150018B (it)
NL (2) NL8002568A (it)
NO (2) NO150916C (it)
PT (2) PT71174A (it)
SE (2) SE8003277L (it)
ZA (2) ZA802695B (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1156661A (en) * 1980-02-25 1983-11-08 Hoffmann-La Roche Limited Phenoxy-aminopropanol derivatives
JPS582343A (ja) * 1981-06-30 1983-01-07 Osaka Soda Co Ltd 耐窒素酸化物性に優れた加硫性ゴム組成物
GB8310556D0 (en) * 1983-04-19 1983-05-25 Beecham Group Plc Compounds
US4550119A (en) * 1983-05-23 1985-10-29 Warner-Lambert Company 2,4-Dihydro-5-[(substituted)phenyl]-4,4-disubstituted-3H-pyrazol-3-ones
US5104892A (en) * 1989-12-11 1992-04-14 American Home Products Corporation Substituted benzimidazole derivatives possessing Class III antiarrhythmic activity
US5541204A (en) * 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
EP1487843A4 (en) 2002-03-20 2010-03-10 Metabolex Inc SUBSTITUTED PHENYLACETIC ACIDS
US7351719B2 (en) 2002-10-31 2008-04-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds
US7199259B2 (en) * 2003-06-20 2007-04-03 Metabolex, Inc. Resolution of α-(phenoxy)phenylacetic acid derivatives
US20060014785A1 (en) * 2004-05-25 2006-01-19 Metabolex, Inc. Bicyclic, substituted triazoles as modulators of ppar and methods of their preparation
EP1751120A4 (en) * 2004-05-25 2010-05-05 Metabolex Inc SUBSTITUTED TRIAZOLE AS PPAR MODULATORS AND MANUFACTURING METHOD THEREFOR
US7714131B2 (en) * 2005-09-23 2010-05-11 Metabolex, Inc. Process for the stereoselective preparation of (−)-halofenate and derivatives thereof
EP2727911B1 (en) * 2012-10-31 2016-12-21 Medizinische Hochschule Hannover Novel means and methods for treating malaria and other parasitic disorders

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1157556A (en) * 1966-06-09 1969-07-09 Egyt Gyogyszervegyeszeti Gyar Novel Benzazole Derivatives and the Preparation thereof
FR1570892A (it) * 1968-06-18 1969-06-13
US3574218A (en) * 1969-08-11 1971-04-06 Egyt Gyogyszervegyeszeti Gyar 2-aryl- or aralkyl-substituted benzazole derivatives
JPS5231858B1 (it) * 1969-12-17 1977-08-17
CH624395A5 (it) 1976-01-08 1981-07-31 Ciba Geigy Ag
DE2609645A1 (de) 1976-03-09 1977-09-15 Boehringer Sohn Ingelheim Aminoalkylheterocyclen
DE2640730C2 (de) * 1976-09-10 1983-08-25 Hoechst Ag, 6230 Frankfurt Benzoxazolyloxy- und Benzothiazolyloxy-phenoxy-Verbindungen und diese enthaltende herbizide Mittel
DE2644833A1 (de) * 1976-10-05 1978-04-20 Boehringer Sohn Ingelheim Neue 1-aryloxy-2-hydroxy-3-alkylenaminopropane und verfahren zu ihrer herstellung
DE2737630A1 (de) 1977-08-20 1979-03-01 Boehringer Mannheim Gmbh Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2801953A1 (de) 1978-01-18 1979-07-19 Boehringer Mannheim Gmbh 4-hydroxy-2-benzimidazolinon-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
DE2801980A1 (de) 1978-01-18 1979-07-19 Boehringer Mannheim Gmbh 4-hydroxy-2-benzimidazolin-thion- derivate, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
EP0003758A1 (de) 1978-02-09 1979-09-05 Ciba-Geigy Ag Verätherte Hydroxy-benzodiheterocyclen und ihre Säureadditionssalze, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate
DE2905876A1 (de) 1979-02-16 1980-08-28 Boehringer Mannheim Gmbh Neue piperidinopropylderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2905877A1 (de) 1979-02-16 1980-08-28 Boehringer Mannheim Gmbh Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
DK187880A (da) 1980-11-05
NO801286L (no) 1980-11-05
CA1146563A (en) 1983-05-17
CH644599A5 (fr) 1984-08-15
IT8021780A1 (it) 1981-11-02
DE3016828A1 (de) 1980-11-13
IT8021779A0 (it) 1980-05-02
AU5809680A (en) 1980-11-06
AU537573B2 (en) 1984-07-05
FI801429A (fi) 1980-11-05
AU542596B2 (en) 1985-02-28
FR2455587B1 (it) 1983-06-24
JPS6033424B2 (ja) 1985-08-02
DE3016827A1 (de) 1980-11-20
IT8021780A0 (it) 1980-05-02
ES491143A0 (es) 1981-04-16
GB2055360A (en) 1981-03-04
AT376418B (de) 1984-11-26
FR2455587A1 (fr) 1980-11-28
US4338330A (en) 1982-07-06
ES491142A0 (es) 1981-03-16
IL59974A0 (en) 1980-07-31
JPS565465A (en) 1981-01-20
ATA238780A (de) 1984-03-15
ZA802695B (en) 1981-08-26
BE883069A (fr) 1980-08-18
GB2055091B (en) 1983-11-09
IT1159060B (it) 1987-02-25
IL59973A (en) 1985-03-31
GR68535B (it) 1982-01-18
NO150916B (no) 1984-10-01
SE8003278L (sv) 1980-11-05
JPS5663946A (en) 1981-05-30
PT71174A (fr) 1980-05-01
FR2455572A1 (fr) 1980-11-28
CH645090A5 (fr) 1984-09-14
FR2455572B1 (fr) 1986-07-25
ATA238680A (de) 1984-04-15
GB2055360B (en) 1983-07-06
PT71175A (fr) 1980-05-01
AU5809580A (en) 1980-11-06
NL8002568A (nl) 1980-11-06
NO150916C (no) 1985-01-16
DK187980A (da) 1980-11-05
ES8103729A1 (es) 1981-03-16
SE8003277L (sv) 1980-11-05
GR68536B (it) 1982-01-18
IE50218B1 (en) 1986-03-05
IE800918L (en) 1980-11-04
IT8021779A1 (it) 1981-11-02
AT376210B (de) 1984-10-25
NO801285L (no) 1980-11-05
ES8104245A1 (es) 1981-04-16
BE883068A (fr) 1980-08-18
ZA802694B (en) 1981-08-26
NL8002567A (nl) 1980-11-06
FI801428A (fi) 1980-11-05
IL59973A0 (en) 1980-07-31
GB2055091A (en) 1981-02-25

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