ES8104245A1 - Procedimiento para la preparacion de derivados de bencimida-zol - Google Patents
Procedimiento para la preparacion de derivados de bencimida-zolInfo
- Publication number
- ES8104245A1 ES8104245A1 ES491143A ES491143A ES8104245A1 ES 8104245 A1 ES8104245 A1 ES 8104245A1 ES 491143 A ES491143 A ES 491143A ES 491143 A ES491143 A ES 491143A ES 8104245 A1 ES8104245 A1 ES 8104245A1
- Authority
- ES
- Spain
- Prior art keywords
- linear
- ramified
- radicals
- radical
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE BENCIMIDAZOL, DE FORMULA GENERAL (I), DONDE R1 PUEDE SER DISTINTOS TIPOS DE RADICALES; R2 Y R3 PUEDEN SER HIDROGENO O DISTINTOS TIPOS DE RADICALES. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II), DONE B Y Q REPRESENTAN DISTINTOS RADICALES, CON UN COMPUESTO DE FORMULA R1Z'', DONDE Z'' PUEDE SER DISTINTOS TIPOS DE RADICALES. ESTOS PRODUCTOS SE APLICAN PARA LA PROFILAXIS Y TRATAMIENTO DE LA HIPERTENSION Y AFECCIONES CARDIOVASCULARES. *FORMULA*
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
LU81225 | 1979-05-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8104245A1 true ES8104245A1 (es) | 1981-04-16 |
ES491143A0 ES491143A0 (es) | 1981-04-16 |
Family
ID=19729148
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES491143A Granted ES491143A0 (es) | 1979-05-04 | 1980-05-02 | Procedimiento para la preparacion de derivados de bencimida-zol |
ES491142A Granted ES491142A0 (es) | 1979-05-04 | 1980-05-02 | Procedimiento para la preparacion de derivados de fenileti- lamina |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES491142A Granted ES491142A0 (es) | 1979-05-04 | 1980-05-02 | Procedimiento para la preparacion de derivados de fenileti- lamina |
Country Status (22)
Country | Link |
---|---|
US (1) | US4338330A (es) |
JP (2) | JPS6033424B2 (es) |
AT (2) | AT376418B (es) |
AU (2) | AU542596B2 (es) |
BE (2) | BE883069A (es) |
CA (1) | CA1146563A (es) |
CH (2) | CH644599A5 (es) |
DE (2) | DE3016828A1 (es) |
DK (2) | DK187980A (es) |
ES (2) | ES491143A0 (es) |
FI (2) | FI801428A (es) |
FR (2) | FR2455572B1 (es) |
GB (2) | GB2055360B (es) |
GR (2) | GR68535B (es) |
IE (1) | IE50218B1 (es) |
IL (2) | IL59973A (es) |
IT (2) | IT1150018B (es) |
NL (2) | NL8002567A (es) |
NO (2) | NO150916C (es) |
PT (2) | PT71174A (es) |
SE (2) | SE8003278L (es) |
ZA (2) | ZA802694B (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1156661A (en) * | 1980-02-25 | 1983-11-08 | Hoffmann-La Roche Limited | Phenoxy-aminopropanol derivatives |
JPS582343A (ja) * | 1981-06-30 | 1983-01-07 | Osaka Soda Co Ltd | 耐窒素酸化物性に優れた加硫性ゴム組成物 |
GB8310556D0 (en) * | 1983-04-19 | 1983-05-25 | Beecham Group Plc | Compounds |
US4550119A (en) * | 1983-05-23 | 1985-10-29 | Warner-Lambert Company | 2,4-Dihydro-5-[(substituted)phenyl]-4,4-disubstituted-3H-pyrazol-3-ones |
US5104892A (en) * | 1989-12-11 | 1992-04-14 | American Home Products Corporation | Substituted benzimidazole derivatives possessing Class III antiarrhythmic activity |
US5541204A (en) * | 1994-12-02 | 1996-07-30 | Bristol-Myers Squibb Company | Aryloxypropanolamine β 3 adrenergic agonists |
JP2005520858A (ja) | 2002-03-20 | 2005-07-14 | メタボレックス, インコーポレイテッド | 置換フェニル酢酸 |
US7351719B2 (en) | 2002-10-31 | 2008-04-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds |
US7199259B2 (en) * | 2003-06-20 | 2007-04-03 | Metabolex, Inc. | Resolution of α-(phenoxy)phenylacetic acid derivatives |
RU2006145872A (ru) * | 2004-05-25 | 2008-06-27 | Метаболекс, Инк. (Us) | Замещенные триазолы в качестве модуляторов ppar и способы их получения |
EP1749000A4 (en) * | 2004-05-25 | 2009-12-30 | Metabolex Inc | BICYCLIC SUBSTITUTED TRIAZOLE AS PPAR MODULATORS AND METHOD FOR THE PRODUCTION THEREOF |
US7714131B2 (en) * | 2005-09-23 | 2010-05-11 | Metabolex, Inc. | Process for the stereoselective preparation of (−)-halofenate and derivatives thereof |
EP2727911B1 (en) * | 2012-10-31 | 2016-12-21 | Medizinische Hochschule Hannover | Novel means and methods for treating malaria and other parasitic disorders |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1157556A (en) * | 1966-06-09 | 1969-07-09 | Egyt Gyogyszervegyeszeti Gyar | Novel Benzazole Derivatives and the Preparation thereof |
FR1570892A (es) | 1968-06-18 | 1969-06-13 | ||
US3574218A (en) * | 1969-08-11 | 1971-04-06 | Egyt Gyogyszervegyeszeti Gyar | 2-aryl- or aralkyl-substituted benzazole derivatives |
JPS5231858B1 (es) * | 1969-12-17 | 1977-08-17 | ||
CH624395A5 (es) | 1976-01-08 | 1981-07-31 | Ciba Geigy Ag | |
DE2609645A1 (de) | 1976-03-09 | 1977-09-15 | Boehringer Sohn Ingelheim | Aminoalkylheterocyclen |
DE2640730C2 (de) * | 1976-09-10 | 1983-08-25 | Hoechst Ag, 6230 Frankfurt | Benzoxazolyloxy- und Benzothiazolyloxy-phenoxy-Verbindungen und diese enthaltende herbizide Mittel |
DE2644833A1 (de) * | 1976-10-05 | 1978-04-20 | Boehringer Sohn Ingelheim | Neue 1-aryloxy-2-hydroxy-3-alkylenaminopropane und verfahren zu ihrer herstellung |
DE2737630A1 (de) | 1977-08-20 | 1979-03-01 | Boehringer Mannheim Gmbh | Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE2801953A1 (de) | 1978-01-18 | 1979-07-19 | Boehringer Mannheim Gmbh | 4-hydroxy-2-benzimidazolinon-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
DE2801980A1 (de) | 1978-01-18 | 1979-07-19 | Boehringer Mannheim Gmbh | 4-hydroxy-2-benzimidazolin-thion- derivate, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel |
EP0003758A1 (de) | 1978-02-09 | 1979-09-05 | Ciba-Geigy Ag | Verätherte Hydroxy-benzodiheterocyclen und ihre Säureadditionssalze, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate |
DE2905877A1 (de) | 1979-02-16 | 1980-08-28 | Boehringer Mannheim Gmbh | Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE2905876A1 (de) | 1979-02-16 | 1980-08-28 | Boehringer Mannheim Gmbh | Neue piperidinopropylderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
-
1980
- 1980-04-30 SE SE8003278A patent/SE8003278L/xx not_active Application Discontinuation
- 1980-04-30 DK DK187980A patent/DK187980A/da not_active Application Discontinuation
- 1980-04-30 FR FR8009846A patent/FR2455572B1/fr not_active Expired
- 1980-04-30 FR FR8009847A patent/FR2455587A1/fr active Granted
- 1980-04-30 PT PT71174A patent/PT71174A/pt unknown
- 1980-04-30 SE SE8003277A patent/SE8003277L/xx not_active Application Discontinuation
- 1980-04-30 BE BE0/200433A patent/BE883069A/fr not_active IP Right Cessation
- 1980-04-30 US US06/145,144 patent/US4338330A/en not_active Expired - Lifetime
- 1980-04-30 BE BE0/200432A patent/BE883068A/fr not_active IP Right Cessation
- 1980-04-30 DK DK187880A patent/DK187880A/da not_active Application Discontinuation
- 1980-04-30 PT PT71175A patent/PT71175A/pt unknown
- 1980-05-01 IL IL59973A patent/IL59973A/xx unknown
- 1980-05-01 IL IL59974A patent/IL59974A0/xx unknown
- 1980-05-02 ES ES491143A patent/ES491143A0/es active Granted
- 1980-05-02 NL NL8002567A patent/NL8002567A/nl not_active Application Discontinuation
- 1980-05-02 CH CH345380A patent/CH644599A5/fr not_active IP Right Cessation
- 1980-05-02 IT IT8021779A patent/IT1150018B/it active
- 1980-05-02 NL NL8002568A patent/NL8002568A/nl not_active Application Discontinuation
- 1980-05-02 CA CA000351169A patent/CA1146563A/en not_active Expired
- 1980-05-02 GR GR61835A patent/GR68535B/el unknown
- 1980-05-02 FI FI801428A patent/FI801428A/fi not_active Application Discontinuation
- 1980-05-02 NO NO801285A patent/NO150916C/no unknown
- 1980-05-02 GR GR61836A patent/GR68536B/el unknown
- 1980-05-02 GB GB8014647A patent/GB2055360B/en not_active Expired
- 1980-05-02 DE DE19803016828 patent/DE3016828A1/de not_active Withdrawn
- 1980-05-02 GB GB8014645A patent/GB2055091B/en not_active Expired
- 1980-05-02 CH CH345280A patent/CH645090A5/fr not_active IP Right Cessation
- 1980-05-02 DE DE19803016827 patent/DE3016827A1/de not_active Withdrawn
- 1980-05-02 NO NO801286A patent/NO801286L/no unknown
- 1980-05-02 FI FI801429A patent/FI801429A/fi not_active Application Discontinuation
- 1980-05-02 ES ES491142A patent/ES491142A0/es active Granted
- 1980-05-02 IT IT8021780A patent/IT1159060B/it active
- 1980-05-05 AU AU58096/80A patent/AU542596B2/en not_active Ceased
- 1980-05-05 IE IE918/80A patent/IE50218B1/en unknown
- 1980-05-05 AU AU58095/80A patent/AU537573B2/en not_active Ceased
- 1980-05-05 ZA ZA00802694A patent/ZA802694B/xx unknown
- 1980-05-05 AT AT0238680A patent/AT376418B/de not_active IP Right Cessation
- 1980-05-05 ZA ZA00802695A patent/ZA802695B/xx unknown
- 1980-05-05 AT AT0238780A patent/AT376210B/de not_active IP Right Cessation
- 1980-05-06 JP JP55059847A patent/JPS6033424B2/ja not_active Expired
- 1980-05-06 JP JP5984680A patent/JPS565465A/ja active Pending
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