MY190351A - Novel compounds and compositions for the inhibition of nampt - Google Patents

Novel compounds and compositions for the inhibition of nampt

Info

Publication number
MY190351A
MY190351A MYPI2013000731A MYPI2013000731A MY190351A MY 190351 A MY190351 A MY 190351A MY PI2013000731 A MYPI2013000731 A MY PI2013000731A MY PI2013000731 A MYPI2013000731 A MY PI2013000731A MY 190351 A MY190351 A MY 190351A
Authority
MY
Malaysia
Prior art keywords
saposin
support
hydrophobic agent
protein
bound
Prior art date
Application number
MYPI2013000731A
Other languages
English (en)
Inventor
Kenneth W Bair
Timm Baumeister
Alexandre J Buckmelter
Karl H Clodfelter
Peter DRAGOVICH
Francis Gosselin
Bingsong Han
Jian Lin
Dominic J Reynolds
Bruce Roth
Chase C Smith
Zhongguo Wang
Xiaozhang Zheng
Po-Wai Yuen
Original Assignee
Genentech Inc
Forma Tm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc, Forma Tm Llc filed Critical Genentech Inc
Publication of MY190351A publication Critical patent/MY190351A/en

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4355—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
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    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
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MYPI2013000731A 2010-09-03 2011-09-02 Novel compounds and compositions for the inhibition of nampt MY190351A (en)

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PH12013500412A1 (en) 2013-04-22
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US10272072B2 (en) 2019-04-30
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