MXPA05008340A - Microbios de vida libre modificados, composiciones de vacuna y metodos de uso de los mismos. - Google Patents
Microbios de vida libre modificados, composiciones de vacuna y metodos de uso de los mismos.Info
- Publication number
- MXPA05008340A MXPA05008340A MXPA05008340A MXPA05008340A MXPA05008340A MX PA05008340 A MXPA05008340 A MX PA05008340A MX PA05008340 A MXPA05008340 A MX PA05008340A MX PA05008340 A MXPA05008340 A MX PA05008340A MX PA05008340 A MXPA05008340 A MX PA05008340A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- modified
- microbes
- vaccine compositions
- living microbes
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000000427 antigen Substances 0.000 abstract 5
- 102000036639 antigens Human genes 0.000 abstract 5
- 108091007433 antigens Proteins 0.000 abstract 5
- 208000035473 Communicable disease Diseases 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 230000004913 activation Effects 0.000 abstract 1
- 230000002238 attenuated effect Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000035800 maturation Effects 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
- A61K39/001103—Receptors for growth factors
- A61K39/001106—Her-2/neu/ErbB2, Her-3/ErbB3 or Her 4/ErbB4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001148—Regulators of development
- A61K39/00115—Apoptosis related proteins, e.g. survivin or livin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001154—Enzymes
- A61K39/001158—Proteinases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001154—Enzymes
- A61K39/001164—GTPases, e.g. Ras or Rho
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001166—Adhesion molecules, e.g. NRCAM, EpCAM or cadherins
- A61K39/001168—Mesothelin [MSLN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/00118—Cancer antigens from embryonic or fetal origin
- A61K39/001182—Carcinoembryonic antigen [CEA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
- A61K39/001188—NY-ESO
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/00119—Melanoma antigens
- A61K39/001192—Glycoprotein 100 [Gp100]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001193—Prostate associated antigens e.g. Prostate stem cell antigen [PSCA]; Prostate carcinoma tumor antigen [PCTA]; PAP or PSGR
- A61K39/001195—Prostate specific membrane antigen [PSMA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0208—Specific bacteria not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/07—Bacillus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/19—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4244—Enzymes
- A61K40/4247—Proteinases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4264—Cancer antigens from embryonic or fetal origin
- A61K40/4266—Carcinoembryonic antigen [CEA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/45—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/46—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/50—Cellular immunotherapy characterised by the use of allogeneic cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Reproductive Health (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Communicable Diseases (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44605103P | 2003-02-06 | 2003-02-06 | |
| US44915303P | 2003-02-21 | 2003-02-21 | |
| US49008903P | 2003-07-24 | 2003-07-24 | |
| US51186903P | 2003-10-15 | 2003-10-15 | |
| US54151504P | 2004-02-02 | 2004-02-02 | |
| PCT/US2004/003671 WO2004084936A2 (en) | 2003-02-06 | 2004-02-06 | Modified free-living microbes, vaccine compositions and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA05008340A true MXPA05008340A (es) | 2006-03-13 |
Family
ID=33102553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA05008340A MXPA05008340A (es) | 2003-02-06 | 2004-02-06 | Microbios de vida libre modificados, composiciones de vacuna y metodos de uso de los mismos. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7833775B2 (enExample) |
| EP (1) | EP1592442A2 (enExample) |
| JP (2) | JP4839209B2 (enExample) |
| KR (1) | KR101173871B1 (enExample) |
| AU (2) | AU2004224425B2 (enExample) |
| CA (1) | CA2515298C (enExample) |
| MX (1) | MXPA05008340A (enExample) |
| WO (1) | WO2004084936A2 (enExample) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8114414B2 (en) * | 1994-11-08 | 2012-02-14 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of cervical cancer |
| US8791237B2 (en) * | 1994-11-08 | 2014-07-29 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of non-hodgkins lymphoma |
| US8771702B2 (en) * | 2001-03-26 | 2014-07-08 | The Trustees Of The University Of Pennsylvania | Non-hemolytic LLO fusion proteins and methods of utilizing same |
| US8481043B2 (en) * | 2001-06-22 | 2013-07-09 | Cpex Pharmaceuticals, Inc. | Nasal immunization |
| KR101192652B1 (ko) * | 2003-02-06 | 2012-10-19 | 앤저 테라퓨틱스 인코퍼레이티드 | 비포식 세포로의 침투가 약화된 리스테리아, 리스테리아를 포함하는 백신, 및 그것의 사용방법 |
| US7695725B2 (en) | 2003-02-06 | 2010-04-13 | Aduro Biotech | Modified free-living microbes, vaccine compositions and methods of use thereof |
| WO2005026203A2 (en) | 2003-09-18 | 2005-03-24 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Dna promoters and anthrax vaccines |
| US7842289B2 (en) | 2003-12-24 | 2010-11-30 | Aduro Biotech | Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof |
| WO2005092372A2 (en) * | 2004-02-06 | 2005-10-06 | Cerus Corporation | Modified bacillus anthracis vaccine compositions and methods of use thereof |
| DE102004013988A1 (de) * | 2004-03-19 | 2005-10-13 | Henkel Kgaa | Der Faktor RecA aus Bacillus licheniformis und recA-inaktivierte Sicherheitsstämme für die biotechnologische Produktion |
| US20060003454A1 (en) * | 2004-07-02 | 2006-01-05 | Conjugon, Inc. | Non-dividing donor cells for gene transfer |
| US20060270040A1 (en) * | 2005-05-26 | 2006-11-30 | Conjugon, Inc. | Compositions and methods for treating tissue |
| EP1928495A2 (en) * | 2005-08-19 | 2008-06-11 | Cerus Corporation | Antibody-mediated enhancement of immune response |
| AU2006304573B2 (en) | 2005-10-17 | 2012-05-24 | Sloan Kettering Institute For Cancer Research | WT1 HLA class II-binding peptides and compositions and methods comprising same |
| WO2008048289A2 (en) | 2005-11-14 | 2008-04-24 | University Of Maryland Biotechnology Institute Off. Of Research Admin./Tech. Dev. | Salmonella based oral vaccines for anthrax |
| WO2007101262A2 (en) * | 2006-02-28 | 2007-09-07 | The Board Of Regents Of The University Of Texas System | Attenuated francisella bacteria |
| US7935804B2 (en) * | 2006-03-01 | 2011-05-03 | Aduro Biotech | Engineered Listeria and methods of use thereof |
| US20070207171A1 (en) * | 2006-03-01 | 2007-09-06 | Cerus Corporation | Engineered listeria and methods of use thereof |
| EP1991263B8 (en) | 2006-03-01 | 2015-02-25 | Aduro Biotech | Engineered listeria and methods of use thereof |
| ES2591029T3 (es) | 2006-04-10 | 2016-11-24 | Sloan Kettering Institute For Cancer Research | Péptidos WT-1 inmunogénicos y métodos para su uso |
| AU2007259329A1 (en) * | 2006-05-12 | 2007-12-21 | Farris, Darise | Anthrax compositions and methods of use and production |
| WO2008094188A2 (en) * | 2006-07-17 | 2008-08-07 | Anza Therapeutics, Inc. | Methods and compositions using listeria for enhancing immunogenicity by prime boost |
| US8124408B2 (en) * | 2006-10-04 | 2012-02-28 | Janssen Pharmaceutica N.V. | Preparation of inactivated artificial antigen presenting cells and their use in cell therapies |
| US8452541B2 (en) * | 2007-06-18 | 2013-05-28 | Microsoft Corporation | Vaccine design methodology |
| AU2008280436A1 (en) * | 2007-07-24 | 2009-01-29 | Stichting Katholieke Universiteit Radboud University Nijmegen Medical Centre | Compositions and methods for generating an immune response in a subject |
| CN102076843A (zh) | 2008-05-19 | 2011-05-25 | 艾杜罗生物科技公司 | 包含prfa*突变体李斯特菌的组合物及其使用方法 |
| CN102947452A (zh) | 2010-05-23 | 2013-02-27 | 艾杜罗生物科技公司 | 使用用于癌症的辅佐治疗的李斯特菌属的方法和组合物 |
| WO2011159814A2 (en) | 2010-06-15 | 2011-12-22 | The Regents Of The University Of California | Novel live recombinant booster vaccine against tuberculosis |
| ES2656498T3 (es) * | 2010-09-07 | 2018-02-27 | Sigma-Aldrich Co. Llc | Células para inmunoprecipitación de cromatina y procedimiento de fabricación de las mismas |
| RS57630B1 (sr) | 2010-11-17 | 2018-11-30 | Aduro Biotech Inc | Metode i sastavi za uzrokovanje imunog odgovora na egfrviii |
| CN103687611A (zh) | 2011-03-11 | 2014-03-26 | 阿德瓦希斯公司 | 基于李斯特菌属的佐剂 |
| CN104684577B (zh) | 2012-01-13 | 2018-05-08 | 纪念斯隆凯特林癌症中心 | 免疫原性wt-1肽及其使用方法 |
| US10058599B2 (en) | 2012-03-12 | 2018-08-28 | Advaxis, Inc. | Suppressor cell function inhibition following Listeria vaccine treatment |
| US10815273B2 (en) | 2013-01-15 | 2020-10-27 | Memorial Sloan Kettering Cancer Center | Immunogenic WT-1 peptides and methods of use thereof |
| PL2945647T3 (pl) | 2013-01-15 | 2021-03-08 | Memorial Sloan Kettering Cancer Center | Immunogenne peptydy wt-1 i sposoby ich zastosowania |
| SG11201702611YA (en) | 2014-10-14 | 2017-04-27 | Univ Pennsylvania | Combination therapy for use in cancer therapy |
| WO2016073381A1 (en) | 2014-11-03 | 2016-05-12 | Cerus Corporation | Compositions and methods for improved car-t cell therapies |
| UY36616A (es) | 2015-04-13 | 2016-10-31 | Aduro Biotech Inc | Fusiones de variante iii del receptor de factor de crecimiento epidérmico-mesotelina y métodos para usar los mismos |
| CN107980044A (zh) | 2015-04-13 | 2018-05-01 | 艾杜罗生物科技公司 | 用于治疗癌症的免疫原性融合蛋白 |
| IL256381B2 (en) | 2015-06-26 | 2024-12-01 | Cerus Corp | Cryoprecipitate preparations and methods for their preparation |
| CA3003097A1 (en) | 2015-10-23 | 2017-04-27 | Cerus Corporation | Plasma compositions and methods of use thereof |
| AU2016369519B2 (en) | 2015-12-16 | 2023-04-20 | Seattle Project Corp. | Neoantigen identification, manufacture, and use |
| WO2018119462A1 (en) | 2016-12-23 | 2018-06-28 | Cerus Corporation | Systems and methods for testing and screening using compound bound substrates |
| MX390725B (es) | 2017-03-03 | 2025-03-21 | Cerus Corp | Kits y metodos para preparar composiciones de plaquetas con patogeno inactivado. |
| CN111315401A (zh) * | 2017-06-16 | 2020-06-19 | 南特生物科学公司 | 细菌疫苗 |
| CA3078744A1 (en) | 2017-10-10 | 2019-04-18 | Gritstone Oncology, Inc. | Neoantigen identification using hotspots |
| AU2018373154B2 (en) | 2017-11-22 | 2025-08-07 | Seattle Project Corp. | Reducing junction epitope presentation for neoantigens |
| CA3087253A1 (en) | 2017-12-29 | 2019-07-04 | Cerus Corporation | Systems and methods for treating biological fluids |
| CN110408634B (zh) * | 2018-04-27 | 2021-08-03 | 苏州若泰医药科技有限公司 | 一种非整合李斯特菌疫苗及抗肿瘤免疫应答方法 |
| CN112533939B (zh) * | 2018-08-02 | 2024-03-19 | 苏州若泰医药科技有限公司 | 一种基于减毒李斯特菌激活的抗原提呈细胞的肿瘤免疫治疗组合物、制备方法和应用 |
| WO2020028794A1 (en) * | 2018-08-02 | 2020-02-06 | The Johns Hopkins University | Compositions comprising annexin v and hpv tumor antigen fusion polypeptides |
| CN114173842A (zh) | 2019-06-22 | 2022-03-11 | 塞鲁斯公司 | 生物流体处理系统 |
| EP3991179A1 (en) | 2019-06-28 | 2022-05-04 | Cerus Corporation | System and methods for implementing a biological fluid treatment device |
| US20230123485A1 (en) * | 2020-03-11 | 2023-04-20 | Superbrewed Food, Inc. | Microbial compositions and uses thereof |
| US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
| WO2022226319A1 (en) * | 2021-04-23 | 2022-10-27 | Wake Forest University Health Sciences | Psoralen-inactivated neisseria gonorrhoeae vaccines and methods thereof |
| KR102717863B1 (ko) | 2023-06-09 | 2024-10-16 | 지보건설 주식회사 | 지반 보강공법 및 그 공법에 적용되는 굴삭기 버킷 |
Family Cites Families (84)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US77263A (en) * | 1868-04-28 | Henry w | ||
| US136738A (en) * | 1873-03-11 | Improvement in combined oil-cans and torches | ||
| US9194A (en) * | 1852-08-17 | Pile-cutting machineby | ||
| US4693981A (en) * | 1983-12-20 | 1987-09-15 | Advanced Genetics Research Institute | Preparation of inactivated viral vaccines |
| US4556556A (en) | 1984-03-23 | 1985-12-03 | Advanced Genetics Research Institute | Vaccine for the prevention of vesicular stomatitis virus infection |
| US4545987A (en) | 1983-12-20 | 1985-10-08 | Advanced Genetics Research Institute | Psoralen inactivated double-stranded RNA viral vaccines |
| US5106619A (en) | 1983-12-20 | 1992-04-21 | Diamond Scientific Co. | Preparation of inactivated viral vaccines |
| US5171568A (en) | 1984-04-06 | 1992-12-15 | Chiron Corporation | Recombinant herpes simplex gb-gd vaccine |
| US4791062A (en) | 1985-02-28 | 1988-12-13 | Diamond Scientific Co. | FVR vaccine |
| EP0318216B2 (en) | 1987-11-18 | 2001-08-29 | Chiron Corporation | NANBV diagnostics |
| DK189788D0 (da) | 1988-04-07 | 1988-04-07 | Wolf Watz Hans | Vaccine |
| IL92996A (en) * | 1989-01-10 | 1996-06-18 | Bisaccia Emil | Photovoltaic compounds as drugs for the treatment of viral infections and a method for the production of vaccines |
| KR0185373B1 (ko) | 1989-03-17 | 1999-05-01 | 로버트 피. 블랙버언 | Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용 |
| AU638719B2 (en) | 1989-05-18 | 1993-07-08 | Novartis Vaccines And Diagnostics, Inc. | Nanbv diagnostics: polynucleotides useful for screening for hepatitis c virus |
| US5180819A (en) | 1989-12-22 | 1993-01-19 | The Trustees Of Columbia University In The City Of New York | Purified myeloblastin, nucleic acid molecule encoding same, and uses thereof |
| US6346611B1 (en) * | 1990-06-11 | 2002-02-12 | Gilead Sciences, Inc. | High affinity TGfβ nucleic acid ligands and inhibitors |
| US5830702A (en) | 1990-10-31 | 1998-11-03 | The Trustees Of The University Of Pennsylvania | Live, recombinant listeria monocytogenes and production of cytotoxic T-cell response |
| FR2686896B1 (fr) | 1992-01-31 | 1995-01-06 | Pasteur Institut | Mutant attenue de listeria monocytogenes; souche recombinante de listeria monocytogenes, utilisation comme vecteurs heterologues d'antigenes vaccinal et utilisation comme vaccin ou composition diagnostique. |
| US5593823A (en) | 1993-06-28 | 1997-01-14 | Cerus Corporation | Method for inactivating pathogens in blood using photoactivation of 4'-primary amino-substituted psoralens |
| US5399719A (en) | 1993-06-28 | 1995-03-21 | Steritech, Inc. | Compounds for the photodecontamination of pathogens in blood |
| US6051237A (en) | 1994-11-08 | 2000-04-18 | The Trustees Of The University Of Pennsylvania | Specific immunotherapy of cancer using a live recombinant bacterial vaccine vector |
| US5691132A (en) | 1994-11-14 | 1997-11-25 | Cerus Corporation | Method for inactivating pathogens in red cell compositions using quinacrine mustard |
| US5877159A (en) | 1995-05-03 | 1999-03-02 | University Of Maryland At Baltimore | Method for introducing and expressing genes in animal cells and live invasive bacterial vectors for use in the same |
| US6682729B1 (en) | 1995-05-03 | 2004-01-27 | University Of Maryland, Baltimore | Method for introducing and expressing genes in animal cells, and live invasive bacterial vectors for use in the same |
| US6150170A (en) | 1998-05-03 | 2000-11-21 | University Of Maryland At Baltimore | Method for introducing and expressing genes in animal cells, and live invasive bacterial vectors for use in the same |
| US6177441B1 (en) | 1995-06-05 | 2001-01-23 | Cerus Corporation | Treating red blood cell solutions with anti-viral agents |
| WO1996039818A1 (en) | 1995-06-07 | 1996-12-19 | Cerus Corporation | Treating red blood cell solutions with anti-viral agents |
| GB9521568D0 (en) | 1995-10-20 | 1995-12-20 | Lynxvale Ltd | Delivery of biologically active polypeptides |
| AU1152397A (en) | 1995-12-20 | 1997-07-14 | Board Of Trustees Of The Leland Stanford Junior University | Methods for in vivo t cell activation by antigen-pulsed dendritic cells |
| ATE254931T1 (de) | 1996-01-05 | 2003-12-15 | Us Gov Health & Human Serv | Mesothelinantigen, verfahren und testsatz zur targetierung |
| US5843459A (en) | 1996-01-19 | 1998-12-01 | Human Gene Therapy Research Institute | Differential inactivation of nucleic acids by chemical modification |
| AU734196B2 (en) | 1996-03-28 | 2001-06-07 | Whitehead Institute | Opsonin-enhanced cells, and methods of modulating an immune response to an antigen |
| EP0808897A1 (en) | 1996-05-21 | 1997-11-26 | I.D.M. Immuno-Designed Molecules | New antigen presenting cells, a process for preparing the same and their use as cellular vaccines |
| KR20000022445A (ko) | 1996-07-10 | 2000-04-25 | 크리스토퍼 엘. 와이트, 스코트 지. 홀퀴스트, 스티븐 엘. 말라스카 | 수상돌기 세포의 활성화 방법 |
| GB9615022D0 (en) | 1996-07-17 | 1996-09-04 | Mini Agriculture & Fisheries | Vaccine preparations |
| US6194204B1 (en) | 1996-08-02 | 2001-02-27 | Center For Blood Research, Inc. | Enrichment of dendritic cells from blood |
| US7273753B2 (en) | 1996-08-02 | 2007-09-25 | Center Of Blood Research | Purification and uses of dendritic cells and monocytes |
| DE19635676A1 (de) | 1996-09-03 | 1998-03-05 | Basf Ag | Feste geschäumte Wirkstoffzubereitungen |
| CN101676268B (zh) * | 1997-01-06 | 2013-09-25 | 塞鲁斯公司 | 用于病原体灭活的脆性化合物 |
| US6093725A (en) | 1997-01-06 | 2000-07-25 | Cerus Corporation | Frangible compounds for pathogen inactivation |
| US6514987B1 (en) | 1997-01-06 | 2003-02-04 | Cerus Corporation | Frangible compounds for pathogen inactivation |
| GB9700939D0 (en) | 1997-01-17 | 1997-03-05 | Microbial Technics Limited | Therapy |
| WO1998033386A1 (en) | 1997-01-31 | 1998-08-06 | Vanderbilt University | Method of delivering antigens for vaccination with a live vector |
| WO1999003976A2 (en) | 1997-07-21 | 1999-01-28 | Cerus Corporation | Method of treating leukocytes, leukocyte compositions and methods of use thereof |
| US6099848A (en) | 1997-11-18 | 2000-08-08 | The Trustees Of The University Of Pennsylvania | Immunogenic compositions comprising DAL/DAT double-mutant, auxotrophic, attenuated strains of Listeria and their methods of use |
| JP2003525848A (ja) | 1997-11-20 | 2003-09-02 | セラス コーポレーション | 病原体を不活化するための新規なソラレン |
| DE19754938B4 (de) | 1997-12-11 | 2006-04-20 | Christoph von Dr. Eichel-Streiber | TGC-Verfahren zur Induktion einer zielgerichteten, somatischen Transgenität |
| US6143551A (en) | 1997-12-29 | 2000-11-07 | Schering Aktiengesellschaft | Delivery of polypeptide-encoding plasmid DNA into the cytosol of macrophages by attenuated listeria suicide bacteria |
| ES2224415T3 (es) | 1998-01-06 | 2005-03-01 | Cerus Corporation | Metodos para inhibir desactivadores patogenos en materiales biologicos. |
| AU756911B2 (en) | 1998-03-20 | 2003-01-23 | Biopolo S.C.R.L. | Processes for improved presentation of antigens by dendritic cells |
| JP2002509716A (ja) | 1998-03-31 | 2002-04-02 | ユニバーシティ テクノロジー コーポレイション | テロメラーゼ抗原に対する免疫応答を惹起するための方法および組成物 |
| US20020155108A1 (en) | 1998-05-04 | 2002-10-24 | Biocrystal, Ltd. | Method for ex vivo loading of antigen presenting cells with antigen, and a vaccine comprising the loaded cells |
| US6254863B1 (en) | 1998-08-12 | 2001-07-03 | Loma Linda University | Non-virulent Porphyromonas gingivalis mutant |
| US6004815A (en) | 1998-08-13 | 1999-12-21 | The Regents Of The University Of California | Bacteria expressing nonsecreted cytolysin as intracellular microbial delivery vehicles to eukaryotic cells |
| GB9918283D0 (en) | 1999-08-03 | 1999-10-06 | Int Centre Genetic Eng & Bio | Hsv vaccines |
| AU7856100A (en) | 1999-10-04 | 2001-05-10 | Vion Pharmaceuticals, Inc. | Methods for treating solid tumors with irradiation and bacteria |
| DE19949594A1 (de) | 1999-10-14 | 2001-04-26 | Deutsches Krebsforsch | Rekombinante attenuierte Listerien zur Immuntherapie |
| US20030077263A1 (en) | 1999-10-29 | 2003-04-24 | Immunex Corporation | Method of activating dendritic cells |
| US6855320B2 (en) | 2000-03-29 | 2005-02-15 | The Trustees Of The University Of Pennsylvania | Fusion of non-hemolytic, truncated form of listeriolysin O to antigens to enhance immunogenicity |
| AU2001255196A1 (en) | 2000-03-29 | 2001-10-08 | The Trustees Of The University Of Pennsylvania | Compositions and methods for enhancing immunogenicity of antigens |
| IL152553A0 (en) | 2000-05-04 | 2003-05-29 | Harvard College | Compounds and methods for the treatment and prevention of bacterial infection |
| US20020150588A1 (en) | 2000-09-21 | 2002-10-17 | Allison James P. | SPAS-1 cancer antigen |
| US7405076B2 (en) | 2000-11-14 | 2008-07-29 | Universite Libre De Bruxelles | Generation and use of dendritic cells |
| US7045122B2 (en) * | 2000-11-16 | 2006-05-16 | Akzo Nobel N.V. | Salmonella vaccine |
| EP1365750A2 (en) | 2000-12-21 | 2003-12-03 | Cerus Corporation | Methods for inactivation of pathogens in biological materials |
| US6783765B2 (en) | 2001-03-23 | 2004-08-31 | Council Of Scientific And Industrial Research | Process for the preparation of a vaccine for the treatment of tuberculosis and other intracellular infections diseases and the vaccine produced by the process |
| EP1373475A2 (en) | 2001-04-02 | 2004-01-02 | Alimentary Health Limited | Immunotherapy based on dendritic cells |
| US7566568B2 (en) | 2001-04-27 | 2009-07-28 | Istituto Superiore Di Sanita | Method for generating highly active human dendritic cells from peripheral blood mononuclear cells |
| US20040022761A1 (en) | 2001-05-11 | 2004-02-05 | Banchereau Jacques F | Compositions and methods for producing antigen-presenting cells |
| WO2003012085A1 (en) | 2001-07-30 | 2003-02-13 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Antigen presenting cells, method for their preparation and their use for cancer vaccines |
| US7413869B2 (en) | 2002-04-05 | 2008-08-19 | Dendreon Corporation | Method for determining potency of antigenic presenting cell based vaccines |
| US7425449B2 (en) | 2002-04-30 | 2008-09-16 | The Regents Of The University Of California | Site specific Listeria integration vectors and methods for using the same |
| US7794728B2 (en) | 2002-05-29 | 2010-09-14 | The Regents Of The University Of California | Attenuated Listeria spp. and methods for using the same |
| US20040009194A1 (en) | 2002-06-21 | 2004-01-15 | Jean-Marie Andrieu | Methods, and compositions for a therapeutic antigen presenting cell vaccine for treatment of immunodeficiency virus |
| AU2002950473A0 (en) | 2002-07-26 | 2002-09-12 | Commonwealth Scientific And Industrial Research Organisation | Expression system |
| US7695725B2 (en) | 2003-02-06 | 2010-04-13 | Aduro Biotech | Modified free-living microbes, vaccine compositions and methods of use thereof |
| KR101192652B1 (ko) | 2003-02-06 | 2012-10-19 | 앤저 테라퓨틱스 인코퍼레이티드 | 비포식 세포로의 침투가 약화된 리스테리아, 리스테리아를 포함하는 백신, 및 그것의 사용방법 |
| US20050281783A1 (en) | 2003-10-15 | 2005-12-22 | Kinch Michael S | Listeria-based EphA2 vaccines |
| US20050175630A1 (en) | 2003-12-23 | 2005-08-11 | Eyal Raz | Immunogenic compositions and methods of use thereof |
| US7842289B2 (en) | 2003-12-24 | 2010-11-30 | Aduro Biotech | Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof |
| WO2005067460A2 (en) | 2003-12-24 | 2005-07-28 | Medimmune, Inc. | Epha2 vaccines |
| WO2005071088A2 (en) | 2003-12-24 | 2005-08-04 | Cerus Corporation | Recombinant nucleic acid molecules encoding fusion proteins comprising antigens and bacterial secretory signal polypeptides, expression cassettes, and bacteria, and methods of use thereof |
| US20070031457A1 (en) | 2004-02-06 | 2007-02-08 | Dubensky Thomas W Jr | Modified Bacillus anthracis, vaccine compositions and methods of use thereof |
| WO2005092372A2 (en) | 2004-02-06 | 2005-10-06 | Cerus Corporation | Modified bacillus anthracis vaccine compositions and methods of use thereof |
-
2004
- 2004-02-06 AU AU2004224425A patent/AU2004224425B2/en not_active Ceased
- 2004-02-06 MX MXPA05008340A patent/MXPA05008340A/es active IP Right Grant
- 2004-02-06 EP EP04749318A patent/EP1592442A2/en not_active Withdrawn
- 2004-02-06 WO PCT/US2004/003671 patent/WO2004084936A2/en not_active Ceased
- 2004-02-06 CA CA2515298A patent/CA2515298C/en not_active Expired - Fee Related
- 2004-02-06 US US10/773,618 patent/US7833775B2/en active Active
- 2004-02-06 KR KR1020057014537A patent/KR101173871B1/ko not_active Expired - Fee Related
- 2004-02-06 JP JP2006508697A patent/JP4839209B2/ja not_active Expired - Fee Related
-
2007
- 2007-02-05 JP JP2007026192A patent/JP2007131639A/ja active Pending
-
2010
- 2010-06-10 AU AU2010202434A patent/AU2010202434A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20040197343A1 (en) | 2004-10-07 |
| WO2004084936A3 (en) | 2005-06-16 |
| EP1592442A2 (en) | 2005-11-09 |
| WO2004084936A8 (en) | 2004-12-16 |
| JP2007131639A (ja) | 2007-05-31 |
| JP4839209B2 (ja) | 2011-12-21 |
| JP2006521376A (ja) | 2006-09-21 |
| AU2004224425A1 (en) | 2004-10-07 |
| CA2515298A1 (en) | 2004-10-07 |
| AU2004224425B2 (en) | 2010-06-24 |
| WO2004084936A2 (en) | 2004-10-07 |
| CA2515298C (en) | 2014-04-08 |
| KR20060008860A (ko) | 2006-01-27 |
| KR101173871B1 (ko) | 2012-08-16 |
| US7833775B2 (en) | 2010-11-16 |
| AU2010202434A1 (en) | 2010-07-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MXPA05008340A (es) | Microbios de vida libre modificados, composiciones de vacuna y metodos de uso de los mismos. | |
| MX2020003995A (es) | Nuevas moleculas de acido nucleico artificiales. | |
| CY1121211T1 (el) | Εμβολιο ιου ερπητα ζωστηρα | |
| CY1121789T1 (el) | Νεες ανοσοενισχυτικες συνθεσεις | |
| MX2020003915A (es) | Proteinas trispecificas y metodos de uso. | |
| MX2018010586A (es) | Nanovacuna de activacion de "sting" para inmunoterapia. | |
| TW200806316A (en) | Yeast-based vaccine for inducing an immune response | |
| BR0316758A (pt) | Vacinas baseadas em levedura como imunoterapia | |
| BR0311995A (pt) | Partìculas semelhantes a vìrus empacotadas para o uso como adjuvantes: método de preparação e uso | |
| BRPI0707779B8 (pt) | antígeno isolado, composição de vacina e método para produção de uma proteína antígeno | |
| AR081809A1 (es) | Composiciones farmaceuticas que comprenden un polipeptido que comprende al menos un motivo cxxc y antigenos heterologos y usos de las mismas | |
| EA201600305A1 (ru) | Вариант белка opc2 pcv2 и содержащие его вирусоподобные частицы | |
| MXPA04000885A (es) | Celulas presentadoras de antigeno, metodo para su preparacion y uso para vacunas contra cancer. | |
| CO6321162A2 (es) | Una vacuna que comprende una cantidad inmunogenica de un antigeno en somastatina y un adyuvante | |
| AR080313A1 (es) | Composiciones de virus de moquillo canino (cdv) recombinante y sus usos | |
| BRPI0815578B8 (pt) | Peptídeo de cdca1, seu uso e composição imunogênica compreendendo o mesmo para induzir imunidade, tratar e/ou prevenir o câncer, bem como método in vitro para induzir uma célula apresentadora de antígeno e uma célula t citotóxica (killer) | |
| CL2012000447A1 (es) | Composición o vacuna que comprende un vector viral de un paramixovirus aviar 8 (apmv-8) recombinante; método para producir dicho vector; y uso para preparar medicamento útil para inducir una respuesta inmunológica. | |
| MX2025004075A (es) | Vacunas para circovirus porcino tipo 3 (pcv3), y produccion y sus usos | |
| AR075484A1 (es) | Pestivirus quimericos | |
| CO6460752A2 (es) | Respuesta inmunitaria reforzada en especies aviares | |
| GEP201706766B (en) | Methods and compositions for vaccinating against staphylococcus aureus | |
| DE602004028029D1 (en) | Rwendung | |
| MX2023012530A (es) | Composición y metodos de vacuna adyuvada. | |
| WO2009077577A3 (en) | Vaccine antigens from piscirickettsia salmonis | |
| NI201700080A (es) | Composiciones de vacuna para el virus del dengue y métodos de uso de las mismas. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB | Transfer or rights | ||
| GB | Transfer or rights | ||
| FG | Grant or registration |