PL2945647T3 - Immunogenne peptydy wt-1 i sposoby ich zastosowania - Google Patents

Immunogenne peptydy wt-1 i sposoby ich zastosowania

Info

Publication number
PL2945647T3
PL2945647T3 PL14741142T PL14741142T PL2945647T3 PL 2945647 T3 PL2945647 T3 PL 2945647T3 PL 14741142 T PL14741142 T PL 14741142T PL 14741142 T PL14741142 T PL 14741142T PL 2945647 T3 PL2945647 T3 PL 2945647T3
Authority
PL
Poland
Prior art keywords
immunogenic
peptides
methods
Prior art date
Application number
PL14741142T
Other languages
English (en)
Inventor
David A. Scheinberg
Tao DAO
Original Assignee
Memorial Sloan Kettering Cancer Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Memorial Sloan Kettering Cancer Center filed Critical Memorial Sloan Kettering Cancer Center
Publication of PL2945647T3 publication Critical patent/PL2945647T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001152Transcription factors, e.g. SOX or c-MYC
    • A61K39/001153Wilms tumor 1 [WT1]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5154Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
PL14741142T 2013-01-15 2014-01-15 Immunogenne peptydy wt-1 i sposoby ich zastosowania PL2945647T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361752799P 2013-01-15 2013-01-15
PCT/US2014/011711 WO2014113490A2 (en) 2013-01-15 2014-01-15 Immunogenic wt-1 peptides and methods of use thereof
EP14741142.5A EP2945647B1 (en) 2013-01-15 2014-01-15 Immunogenic wt-1 peptides and methods of use thereof

Publications (1)

Publication Number Publication Date
PL2945647T3 true PL2945647T3 (pl) 2021-03-08

Family

ID=51210182

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14741142T PL2945647T3 (pl) 2013-01-15 2014-01-15 Immunogenne peptydy wt-1 i sposoby ich zastosowania

Country Status (17)

Country Link
US (1) US9919037B2 (pl)
EP (2) EP3769782A1 (pl)
JP (4) JP6486278B2 (pl)
CN (4) CN116253788A (pl)
AU (4) AU2014207615B2 (pl)
CA (1) CA2898099A1 (pl)
CY (1) CY1123563T1 (pl)
DK (1) DK2945647T3 (pl)
ES (1) ES2832546T3 (pl)
HR (1) HRP20201867T1 (pl)
HU (1) HUE052541T2 (pl)
LT (1) LT2945647T (pl)
PL (1) PL2945647T3 (pl)
PT (1) PT2945647T (pl)
RS (1) RS61173B1 (pl)
SI (1) SI2945647T1 (pl)
WO (1) WO2014113490A2 (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2626238C (en) 2005-10-17 2015-10-06 Sloan Kettering Institute For Cancer Research Wt1 hla class ii-binding peptides and compositions and methods comprising same
WO2007120673A2 (en) 2006-04-10 2007-10-25 Sloan Kettering Institute For Cancer Research Immunogenic wt-1 peptides and methods of use thereof
EP2802347B1 (en) 2012-01-13 2019-01-09 Memorial Sloan Kettering Cancer Center Immunogenic wt-1 peptides and methods of use thereof
EP3769782A1 (en) 2013-01-15 2021-01-27 Memorial Sloan Kettering Cancer Center Immunogenic wt-1 peptides and methods of use thereof
US10815273B2 (en) 2013-01-15 2020-10-27 Memorial Sloan Kettering Cancer Center Immunogenic WT-1 peptides and methods of use thereof
FR3030573B1 (fr) 2014-12-18 2021-06-11 Veolia Proprete Biostimulation in-situ de l'hydrolyse de la matiere organique pour optimiser sa valorisation energetique
DK3377516T3 (da) 2015-11-20 2022-09-19 Memorial Sloan Kettering Cancer Center Sammensætning til behandling af cancer
EP3411475A4 (en) 2016-02-06 2019-09-11 President and Fellows of Harvard College REGENERATION OF THE HEMATOPOIETIC NICHE TO RECONSTITUTE IMMUNITY
MX2018012152A (es) * 2016-04-06 2019-02-07 Immatics Biotechnologies Gmbh Nuevos peptidos y nuevas combinaciones de peptidos para el uso en la inmunoterapia contra la leucemia mieloide aguda (aml) y otros tipos de cancer.
US20200010528A1 (en) 2017-03-15 2020-01-09 Cue Biopharma, Inc. Methods for modulating an immune response
EP3600340A4 (en) 2017-03-31 2021-01-20 ACT Genomics (IP) Co., Ltd. CLASSIFICATION SYSTEM FOR CANCER-SPECIFIC IMMUNOGENIC EPITOPES
WO2018227205A1 (en) * 2017-06-09 2018-12-13 President And Fellows Of Harvard College Compositions for inducing an immune response
WO2019006401A2 (en) * 2017-06-30 2019-01-03 Advaxis, Inc. LISTERIA-BASED IMMUNOGENIC COMPOSITIONS COMPRISING HETERICCLIENT WILMS TUMOR PROTEIN ANTIGENS AND METHODS OF USE THEREOF
CN113260369A (zh) * 2018-08-10 2021-08-13 优特力克斯有限公司 癌抗原特异性细胞毒性t细胞
TW202039542A (zh) * 2018-12-19 2020-11-01 美商庫爾生物製藥有限公司 多聚體t細胞調節多肽及其使用方法
MX2021012422A (es) * 2019-04-10 2022-01-19 Slsg Ltd Llc Composición de inmunoterapia multivalente y métodos para usarse en el tratamiento de cánceres positivos a la proteína del tumor de wilms 1 (wt1).
WO2021138447A1 (en) 2019-12-31 2021-07-08 Elixirgen Therapeutics, Inc. Temperature-based transient delivery of nucleic acids and proteins to cells and tissues
WO2021142007A1 (en) * 2020-01-09 2021-07-15 Arizona Board Of Regents On Behalf Of Arizona State University Antibodies and method of producing antibodies
WO2021194940A1 (en) * 2020-03-27 2021-09-30 Children's National Medical Center Sars-cov-2-specific t cells and methods of treatment using them
CN111647066B (zh) * 2020-07-01 2020-12-18 维肽瀛(上海)生物技术有限公司 Wt1多肽肿瘤抑制剂
CN113730562A (zh) * 2021-09-10 2021-12-03 中国人民解放军陆军军医大学 以壳聚糖修饰plga的wt1多肽纳米粒疫苗及其制备方法和应用

Family Cites Families (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2016100A (en) 1932-01-06 1935-10-01 Schwarzkopf Erich Thermo-magnetically actuated source of power
US2015101A (en) 1933-08-16 1935-09-24 Edna W Dieckmann Terminal fixture aperture indicator
US2016103A (en) 1933-09-01 1935-10-01 Hugo J Chott Dental aligning and testing device
US2016101A (en) 1934-03-26 1935-10-01 Charles A Towne Apparatus for drawing tabs from addressograph plate carriers
US4722848A (en) 1982-12-08 1988-02-02 Health Research, Incorporated Method for immunizing animals with synthetically modified vaccinia virus
US5837249A (en) 1985-04-19 1998-11-17 The Wistar Institute Method for generating an immunogenic T cell response protective against a virus
US5726288A (en) 1989-11-13 1998-03-10 Massachusetts Institute Of Technology Localization and characterization of the Wilms' tumor gene
US5229115A (en) 1990-07-26 1993-07-20 Immunex Corporation Adoptive immunotherapy with interleukin-7
JPH06505486A (ja) 1991-02-07 1994-06-23 モレキュメティクス,リミティド βターンおよびβバルジのコンフォメーション的に制限された模倣物およびそれらを含有するペプチド
WO1994021287A1 (en) 1993-03-15 1994-09-29 The Government Of The United States Of America As Represented By The Department Of Health And Human Services Peptide coated dendritic cells as immunogens
WO1995029240A1 (en) 1994-04-22 1995-11-02 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Isolation and characterization of a novel primate t-cell lymphotropic virus and the use of this virus or components thereof in diagnostics assays and vaccines
US5622835A (en) 1994-04-28 1997-04-22 The Wistar Institute Of Anatomy & Biology WT1 monoclonal antibodies
US5643786A (en) 1995-01-27 1997-07-01 The United States Of America As Represented By The Department Of Health And Human Services Method for isolating dendritic cells
US6156316A (en) 1995-05-08 2000-12-05 Sloan-Kettering Institute For Cancer Research Oncogene fusion protein peptide vaccines
JPH11171896A (ja) 1995-09-19 1999-06-29 Kirin Brewery Co Ltd 新規ペプチド化合物およびその医薬組成物
US5981217A (en) 1995-12-11 1999-11-09 Mayo Foundation For Medical Education And Research DNA encoding TGF-β inducible early factor-1 (TIEF-1), a gene expressed by osteoblasts
PT879282E (pt) 1996-01-17 2003-11-28 Imp College Innovations Ltd Imunoterapia utilizando linfocitos t citotoxicos (ctl)
US5853719A (en) 1996-04-30 1998-12-29 Duke University Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA
US6207375B1 (en) 1996-12-11 2001-03-27 Mayo Foundation For Medical Educational & Research TGF-β inducible early factor-1 (TIEF-1) and a method to detect breast cancer
ID27813A (id) 1998-01-28 2001-04-26 Corixa Corp Senyawa-senyawa untuk terapi dan diagnosa kanker paru-paru dan metoda untuk penggunaannya
EP2048160B1 (en) 1998-07-31 2015-01-07 International Institute of Cancer Immunology, Inc. Tumor antigen based on products of the tumor suppressor gene WT1
US7115272B1 (en) 1998-09-30 2006-10-03 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
US7144581B2 (en) 2000-10-09 2006-12-05 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
US7329410B1 (en) 1998-09-30 2008-02-12 Corixa Corporation Compositions and method for WT1 specific immunotherapy
US20120301492A1 (en) * 1998-09-30 2012-11-29 Corixa Corporation Compositions and methods for wt1 specific immunotherapy
US20030072767A1 (en) 1998-09-30 2003-04-17 Alexander Gaiger Compositions and methods for WT1 specific immunotherapy
US20030235557A1 (en) 1998-09-30 2003-12-25 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
US7901693B2 (en) 1998-09-30 2011-03-08 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
US7063854B1 (en) 1998-09-30 2006-06-20 Corixa Corporation Composition and methods for WTI specific immunotherapy
US7655249B2 (en) 1998-09-30 2010-02-02 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
GB9823897D0 (en) 1998-11-02 1998-12-30 Imp College Innovations Ltd Immunotherapeutic methods and molecules
WO2000037491A2 (en) 1998-12-22 2000-06-29 Genset Dnas encoding proteins with signal sequences
AU3395900A (en) 1999-03-12 2000-10-04 Human Genome Sciences, Inc. Human lung cancer associated gene sequences and polypeptides
AU3755800A (en) 1999-03-15 2000-10-04 Introgen Therapeutics, Inc. Dendritic cells transduced with a wild-type self gene elicit potent antitumor immune responses
US6593299B1 (en) 1999-04-21 2003-07-15 University Of Florida Research Foundation, Inc. Compositions and methods for controlling pests
WO2001025273A2 (en) 1999-10-04 2001-04-12 Corixa Corporation Compositions and methods for wt1 specific immunotherapy
US20030082194A1 (en) 2000-02-22 2003-05-01 Alexander Gaiger Compositions and methods for diagnosis and therapy of malignant mesothelioma
NZ521430A (en) 2000-02-22 2004-04-30 Corixa Corp Compositions comprising 1-4 antigenic peptide fragments of the Wilms' tumour gene product for treatment or prevention of malignant mesothelioma
US20040002068A1 (en) 2000-03-01 2004-01-01 Corixa Corporation Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
US6861234B1 (en) 2000-04-28 2005-03-01 Mannkind Corporation Method of epitope discovery
EP1209226A3 (en) 2000-11-07 2002-06-05 GSF-Forschungszentrum für Umwelt und Gesundheit GmbH Maturation of dendritic cells by recombinant heat shock protein 70 (hsp70)
JP3728439B2 (ja) 2001-03-22 2005-12-21 治夫 杉山 Wt1改変ペプチド
US8771702B2 (en) 2001-03-26 2014-07-08 The Trustees Of The University Of Pennsylvania Non-hemolytic LLO fusion proteins and methods of utilizing same
ATE494905T1 (de) 2001-06-29 2011-01-15 Chugai Pharmaceutical Co Ltd Krebsimpfstoff mit einem krebs-antigen auf grundlage des produkts aus dem tumorunterdrückungsgen wt1 und einem kationischen liposom
US7553494B2 (en) 2001-08-24 2009-06-30 Corixa Corporation WT1 fusion proteins
EP1447091A4 (en) 2001-09-28 2008-02-13 Institute Of Can International NEW METHOD FOR INDUCTION OF ANTIGEN SPECIFIC T CELLS
JPWO2003028758A1 (ja) 2001-09-28 2005-01-13 治夫 杉山 抗原特異的t細胞の誘導方法
US20030072761A1 (en) 2001-10-16 2003-04-17 Lebowitz Jonathan Methods and compositions for targeting proteins across the blood brain barrier
US20030175272A1 (en) 2002-03-07 2003-09-18 Medcell Biologics, Inc. Re-activated T-cells for adoptive immunotherapy
AU2003242305A1 (en) 2002-06-12 2003-12-31 Chugai Seiyaku Kabushiki Kaisha Hla-a24-restricted cancer antigen peptide
WO2004084936A2 (en) 2003-02-06 2004-10-07 Cerus Corporation Modified free-living microbes, vaccine compositions and methods of use thereof
US20050008618A1 (en) 2003-02-27 2005-01-13 Howard Kaufman Composition for delivering an agent to a target cell and uses thereof
CA2514288C (en) 2003-03-05 2015-07-07 Dendreon Corporation Compositions and methods employing alternative reading frame polypeptides for the treatment of cancer and infectious disease
EP2343083B1 (en) * 2003-06-27 2014-01-15 International Institute of Cancer Immunology, Inc. Method of diagnosing cancer comprising the measurement of WT1-specific CTL precursor cells
US20050147621A1 (en) 2003-10-10 2005-07-07 Higgins Darren E. Use of bacterial 5' untranslated regions for nucleic acid expression
CN100513563C (zh) 2003-11-05 2009-07-15 株式会社国际癌症免疫研究所 Wt1衍生的hla-dr-结合抗原肽
EP1708732B2 (en) 2003-12-01 2016-05-18 Sloan-Kettering Institute For Cancer Research Synthetic hla binding peptide analogues and uses thereof
DE602004020266D1 (de) 2003-12-05 2009-05-07 Multimmune Gmbh Therapeutische und diagnostische anti-hsp 70-antikörper
EP1550458A1 (en) 2003-12-23 2005-07-06 Vectron Therapeutics AG Synergistic liposomal adjuvants
WO2005087260A1 (en) 2004-03-04 2005-09-22 Corixa Corporation Co-encapsulated wt1 polypeptide and immunostimulant microsphere formulations and methods thereof
US20050214268A1 (en) 2004-03-25 2005-09-29 Cavanagh William A Iii Methods for treating tumors and cancerous tissues
US20050221481A1 (en) 2004-03-30 2005-10-06 Istituto Superiore Di Sanita' Amplification of T cells from human cord blood in serum-deprived culture stimulated with stem cell factor, interleukin-7 and interleukin-2
WO2005095598A1 (ja) 2004-03-31 2005-10-13 International Institute Of Cancer Immunology, Inc. Wt1由来の癌抗原ペプチド
US9629927B2 (en) 2005-07-29 2017-04-25 Sloan-Kettering Institute For Cancer Research Single wall nanotube constructs and uses thereof
CA2626238C (en) 2005-10-17 2015-10-06 Sloan Kettering Institute For Cancer Research Wt1 hla class ii-binding peptides and compositions and methods comprising same
CN101336249A (zh) 2005-11-30 2008-12-31 株式会社癌免疫研究所 新型肽化合物
PL1988163T3 (pl) 2006-02-22 2012-11-30 Int Inst Cancer Immunology Inc Ograniczony do hla-a*3303 peptyd wt1 i zawierająca go kompozycja farmaceutyczna
US8288355B2 (en) 2006-03-29 2012-10-16 International Institute Of Cancer Immunology, Inc. siRNA specific to WT1 17AA(−)isoform and use thereof
WO2007120673A2 (en) * 2006-04-10 2007-10-25 Sloan Kettering Institute For Cancer Research Immunogenic wt-1 peptides and methods of use thereof
WO2007120603A2 (en) 2006-04-10 2007-10-25 Sloan Kettering Institute For Cancer Research Immunogenic bcr-abl peptides and methods of use thereof
NZ600281A (en) 2006-12-27 2013-03-28 Harvard College Compositions and methods for the treatment of infections and tumors
CN102335439B (zh) 2006-12-28 2015-04-22 株式会社癌免疫研究所 Hla-a*1101限制的wt1肽及含有其的药物组合物
CN105664147A (zh) 2007-02-07 2016-06-15 日本电气株式会社 用于癌症的治疗剂
CN104312974B (zh) 2007-02-27 2018-09-04 株式会社癌免疫研究所 活化辅助t细胞的方法以及用于该方法的组合物
EA201300101A1 (ru) 2007-05-24 2014-02-28 Глаксосмитклайн Байолоджикалс С.А. Лиофилизированная антигенная композиция
KR100995340B1 (ko) 2007-11-19 2010-11-19 재단법인서울대학교산학협력재단 자연 살해 t 세포의 리간드와 항원을 적재한 단핵구 또는미분화 골수성 세포를 포함하는 백신
AU2008332278C1 (en) 2007-12-05 2013-10-03 International Institute Of Cancer Immunology, Inc. Cancer vaccine composition
KR100900837B1 (ko) 2007-12-07 2009-06-04 (주)두비엘 리포펩타이드와 폴리(i:c)를 아쥬반트로 포함하는 강력한백신 조성물
EP2283112B1 (en) 2008-05-19 2016-10-12 Aduro Biotech Compositions comprising prfa*mutant listeria and methods of use thereof
US20110318380A1 (en) 2008-10-01 2011-12-29 Dako Denmark A/S MHC Multimers in Cancer Vaccines and Immune Monitoring
AR076349A1 (es) 2009-04-23 2011-06-01 Int Inst Cancer Immunology Inc Peptido auxiliar del antigeno del cancer
US20130288236A1 (en) 2009-11-11 2013-10-31 Quest Diagnostics Investments Incorporated Wt1 mutations for prognosis of myeloproliferative disorders
US20110136141A1 (en) 2009-12-03 2011-06-09 Abbott Laboratories Peptide reagents and method for inhibiting autoantibody antigen binding
WO2011100754A1 (en) 2010-02-15 2011-08-18 The Trustees Of The University Of Pennsylvania Live listeria-based vaccines for central nervous system therapy
SG10202108581TA (en) 2010-10-05 2021-09-29 Int Inst Cancer Immunology Inc Method for activating helper t cell
AP2013007158A0 (en) 2011-03-11 2013-10-31 Gilead Calistoga Llc Combination therapies for hematologic malignancies
CN103764826A (zh) 2011-06-28 2014-04-30 株式会社癌免疫研究所 肽癌抗原-特异性t细胞的受体基因
CA2843386A1 (en) 2011-07-29 2013-02-07 Riken Cell for use in immunotherapy which contains modified nucleic acid construct encoding wilms tumor gene product or fragment thereof, method for producing said cell, and said nucleic acid construct
US9539299B2 (en) 2011-10-27 2017-01-10 International Institute Of Cancer Immunology, Inc. Combination therapy with WT1 peptide vaccine and temozolomide
WO2013089252A1 (ja) 2011-12-14 2013-06-20 国立大学法人 高知大学 ヘルパーt細胞誘導性ポリペプチドの改変
US9303079B2 (en) 2012-04-02 2016-04-05 Moderna Therapeutics, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
CN107557334B (zh) 2012-05-03 2021-06-25 弗雷德哈钦森癌症研究中心 增强亲和力的t细胞受体及其制备方法
EP2911683B1 (en) 2012-10-23 2019-09-25 Ubivac, LLC Allogeneic autophagosome-enriched composition for the treatment of disease
SG10201705028WA (en) 2012-12-17 2017-07-28 Otsuka Pharma Co Ltd Method for activating helper t cell
CN104968782B (zh) 2012-12-26 2019-09-06 生物科莫公司 利用人副流感2型病毒载体的疫苗
EP3769782A1 (en) 2013-01-15 2021-01-27 Memorial Sloan Kettering Cancer Center Immunogenic wt-1 peptides and methods of use thereof
US10071051B2 (en) 2013-02-05 2018-09-11 Nitto Denko Corporation WT1 peptide cancer vaccine composition for transdermal administration
KR102045029B1 (ko) 2013-02-05 2019-11-14 닛토덴코 가부시키가이샤 점막 투여용 wt1 펩티드 암 백신 조성물
KR20140100419A (ko) 2013-02-05 2014-08-14 닛토덴코 가부시키가이샤 경피 투여용 wt1 펩티드 암 백신 조성물
EP2762156A1 (en) 2013-02-05 2014-08-06 Nitto Denko Corporation Tape preparation of WT1 peptide cancer vaccine for transdermal administration
WO2014127296A1 (en) 2013-02-14 2014-08-21 Immunocellular Therapeutics, Ltd Cancer vaccines and vaccination methods
JP6294868B2 (ja) 2013-03-12 2018-03-14 大日本住友製薬株式会社 液体水性組成物
EA201992251A1 (ru) 2013-03-15 2020-05-08 Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания Противораковые вакцины и способы лечения с их применением
WO2014157692A1 (ja) 2013-03-29 2014-10-02 大日本住友製薬株式会社 Wt1抗原ペプチドコンジュゲートワクチン
SG11201508521SA (en) 2013-04-25 2015-11-27 Vaximm Ag Salmonella-based vectors for cancer immunotherapy targeting wilms' tumor gene wt1
WO2014185387A1 (ja) 2013-05-13 2014-11-20 株式会社癌免疫研究所 免疫療法の臨床効果の予測法
WO2015002134A1 (ja) 2013-07-02 2015-01-08 公益財団法人がん研究会 細胞性免疫誘導ワクチン
JP6697386B2 (ja) 2013-11-22 2020-05-20 ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ イリノイ 改変された高親和性ヒトt細胞受容体
WO2015090584A1 (en) 2013-12-18 2015-06-25 Vaximm Gmbh Mafinex-Technologiezentrum Novel msln targeting dna vaccine for cancer immunotherapy
EP4070818A3 (en) 2014-01-06 2023-01-11 The Trustees of the University of Pennsylvania Pd1 and pdl1 antibodies and vaccine combinations and use of same for immunotherapy
JP6005305B2 (ja) 2014-02-26 2016-10-12 テラ株式会社 Wt1抗原性ポリペプチド、及び該ポリペプチドを含む抗腫瘍剤
US10023841B2 (en) 2014-05-23 2018-07-17 Baylor Research Institute Methods and compositions for treating breast cancer with dendritic cell vaccines
KR20170092660A (ko) 2014-12-11 2017-08-11 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 혈관 신생병의 면역 요법
CN108350411B (zh) 2015-06-25 2021-06-22 白川利朗 口服肿瘤疫苗
US20190054112A1 (en) 2015-09-18 2019-02-21 Moderna Therapeutics, Inc. Polynucleotide formulations for use in the treatment of renal diseases

Also Published As

Publication number Publication date
CY1123563T1 (el) 2022-03-24
EP2945647A4 (en) 2016-11-09
AU2018241209B2 (en) 2020-07-09
HRP20201867T1 (hr) 2021-02-05
ES2832546T3 (es) 2021-06-10
WO2014113490A2 (en) 2014-07-24
CN105377291A (zh) 2016-03-02
CA2898099A1 (en) 2014-07-24
AU2020250313B2 (en) 2022-12-15
WO2014113490A3 (en) 2015-10-22
CN110078813B (zh) 2023-03-28
CN110078813A (zh) 2019-08-02
AU2023201564A1 (en) 2023-06-01
US20150352201A1 (en) 2015-12-10
AU2018241209A1 (en) 2018-11-01
SI2945647T1 (sl) 2021-01-29
JP2016506907A (ja) 2016-03-07
DK2945647T3 (da) 2020-11-16
AU2014207615B2 (en) 2018-11-01
JP2019122377A (ja) 2019-07-25
AU2020250313A1 (en) 2020-11-12
JP6853842B2 (ja) 2021-03-31
RS61173B1 (sr) 2021-01-29
EP2945647A2 (en) 2015-11-25
JP6486278B2 (ja) 2019-03-20
JP2022125121A (ja) 2022-08-26
JP2021040663A (ja) 2021-03-18
US9919037B2 (en) 2018-03-20
EP2945647B1 (en) 2020-09-09
CN116253788A (zh) 2023-06-13
HUE052541T2 (hu) 2021-05-28
AU2014207615A1 (en) 2015-07-30
LT2945647T (lt) 2021-02-25
EP3769782A1 (en) 2021-01-27
PT2945647T (pt) 2020-11-26
JP7097943B2 (ja) 2022-07-08
CN105377291B (zh) 2019-04-02
CN116789792A (zh) 2023-09-22

Similar Documents

Publication Publication Date Title
EP2945647A4 (en) IMMUNOGENIC WT-1 PEPTIDES AND METHODS OF USE
IL280155A (en) Anti- SIGLEC-8 antibodies and methods of using them
HK1204261A1 (en) Immunogenic wt-1 peptides and methods of use thereof wt-1
IL290547A (en) Antibodies and methods of use
IL244495B (en) Anti-alpha-synuclein antibodies and methods of use
EP2999474A4 (en) THERAPEUTIC AND METHOD OF USE
HK1225612A1 (zh) 抗ly6e抗體及使用方法
HK1225645A1 (zh) Pcv2b趨異株疫苗組合物以及使用方法
HK1221641A1 (zh) 疫苗組合物及使用方法
HK1218247A1 (zh) 益生菌和使用方法
SG11201507276UA (en) Improved methods of use for recombinant human secretoglobins
SG11201601263WA (en) Recombinant microorganisms and methods of use thereof
EP2950818A4 (en) TUMORIN VEGETABLES AND METHOD FOR USE THEREOF