MX9206847A - Derivados de indolpirrolcarbazol, proceso para su preparacion y medicamento que los contiene - Google Patents
Derivados de indolpirrolcarbazol, proceso para su preparacion y medicamento que los contieneInfo
- Publication number
- MX9206847A MX9206847A MX9206847A MX9206847A MX9206847A MX 9206847 A MX9206847 A MX 9206847A MX 9206847 A MX9206847 A MX 9206847A MX 9206847 A MX9206847 A MX 9206847A MX 9206847 A MX9206847 A MX 9206847A
- Authority
- MX
- Mexico
- Prior art keywords
- group
- groups
- indolpirrolcarbazol
- medication
- derivatives
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000005018 aryl alkenyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000000020 sulfo group Chemical group O=S(=O)([*])O[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/044—Pyrrole radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Silicon Polymers (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP34191691 | 1991-11-29 | ||
| JP6926992 | 1992-02-18 | ||
| JP25730692 | 1992-09-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9206847A true MX9206847A (es) | 1993-06-30 |
Family
ID=27300000
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9206847A MX9206847A (es) | 1991-11-29 | 1992-11-27 | Derivados de indolpirrolcarbazol, proceso para su preparacion y medicamento que los contiene |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP0545195B1 (enExample) |
| JP (1) | JP2629542B2 (enExample) |
| KR (1) | KR100275976B1 (enExample) |
| AT (1) | ATE130617T1 (enExample) |
| AU (1) | AU650376B2 (enExample) |
| BG (1) | BG61036B1 (enExample) |
| CA (1) | CA2083534C (enExample) |
| CZ (1) | CZ287304B6 (enExample) |
| DE (1) | DE69206242T2 (enExample) |
| DK (1) | DK0545195T3 (enExample) |
| DZ (1) | DZ1634A1 (enExample) |
| ES (1) | ES2079774T3 (enExample) |
| FI (1) | FI106864B (enExample) |
| GR (1) | GR3018527T3 (enExample) |
| HU (3) | HU9203754D0 (enExample) |
| IL (1) | IL103844A (enExample) |
| MX (1) | MX9206847A (enExample) |
| MY (1) | MY114655A (enExample) |
| NO (1) | NO178929C (enExample) |
| NZ (1) | NZ245203A (enExample) |
| PL (1) | PL171468B1 (enExample) |
| RO (1) | RO113469B1 (enExample) |
| RU (1) | RU2117671C1 (enExample) |
| SA (1) | SA93130351B1 (enExample) |
| TW (1) | TW224469B (enExample) |
| WO (1) | WO1993011145A1 (enExample) |
| YU (1) | YU48963B (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT760375E (pt) * | 1994-05-09 | 2004-04-30 | Banyu Pharma Co Ltd | Derivado de indolopiprolocarbazole anti-tumoral |
| WO1995030682A1 (en) * | 1994-05-09 | 1995-11-16 | Banyu Pharmaceutical Co., Ltd. | Antitumor indolopyprolocarbazole derivative |
| WO1995034663A1 (en) * | 1994-06-13 | 1995-12-21 | Banyu Pharmaceutical Co., Ltd. | Gene coding for glycosyltransferase and use thereof |
| WO1996004293A1 (en) * | 1994-08-02 | 1996-02-15 | Banyu Pharmaceutical Co., Ltd. | Antitumor indolopyrrolocarbazoles |
| US5705511A (en) * | 1994-10-14 | 1998-01-06 | Cephalon, Inc. | Fused pyrrolocarbazoles |
| US5475110A (en) * | 1994-10-14 | 1995-12-12 | Cephalon, Inc. | Fused Pyrrolocarbazoles |
| US5594009A (en) * | 1994-10-14 | 1997-01-14 | Cephalon, Inc. | Fused pyrrolocarbazoles |
| US5591855A (en) * | 1994-10-14 | 1997-01-07 | Cephalon, Inc. | Fused pyrrolocarbazoles |
| AU6836696A (en) * | 1995-09-05 | 1997-03-27 | Banyu Pharmaceutical Co., Ltd. | Antitumor indolopyrrolocarbazole derivatives |
| US5616724A (en) * | 1996-02-21 | 1997-04-01 | Cephalon, Inc. | Fused pyrrolo[2,3-c]carbazole-6-ones |
| AU710669B2 (en) * | 1996-08-22 | 1999-09-23 | Bristol-Myers Squibb Company | Cytotoxic amino sugar and related sugar derivatives of indolopyrrolocarbazoles |
| GB9811624D0 (en) * | 1998-05-29 | 1998-07-29 | Merck Sharp & Dohme | Therapeutic use |
| US6013646A (en) * | 1998-07-02 | 2000-01-11 | Bayer Corporation | Indolocarbazole derivatives useful for the treatment of neurodegenerative diseases and cancer |
| US6833373B1 (en) | 1998-12-23 | 2004-12-21 | G.D. Searle & Co. | Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia |
| US6858598B1 (en) | 1998-12-23 | 2005-02-22 | G. D. Searle & Co. | Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia |
| WO2004083228A1 (ja) | 1999-09-10 | 2004-09-30 | Katsuhisa Kojiri | インドロピロロカルバゾール誘導体及び抗腫瘍剤 |
| FR2801054B1 (fr) * | 1999-11-17 | 2003-06-13 | Adir | Nouveaux derives de 12,13-(pyranosyl)-indolo[2,3-a]pyrrolo [3,4-c]carbazole et 12,13-(pyranosyl)-furo[3,4-c]indolo [2,3-a]carbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| ES2210127T3 (es) | 2000-02-24 | 2004-07-01 | Banyu Pharmaceutical Co., Ltd. | Procedimiento para preparar derivados de indolopirrolocarbazol, compuestos intermedios y procedimiento de preparacion de los compuestos intermedios. |
| US6677450B2 (en) | 2000-10-06 | 2004-01-13 | Bristol-Myers Squibb Company | Topoisomerase inhibitors |
| US6653290B2 (en) | 2000-10-06 | 2003-11-25 | Bristol-Myers Squibb Company | Tumor proliferation inhibitors |
| US6610727B2 (en) | 2000-10-06 | 2003-08-26 | Bristol-Myers Squibb Company | Anhydro sugar derivatives of indolocarbazoles |
| US6555677B2 (en) | 2000-10-31 | 2003-04-29 | Merck & Co., Inc. | Phase transfer catalyzed glycosidation of an indolocarbazole |
| RU2003131269A (ru) | 2001-03-22 | 2005-05-10 | Бристол-Маерс Сквибб Компани (Us) | Производные индолопирролокарбазолов и сахаров, цитотоксические и селективные по отношению к топоизомеразе i |
| US6559299B2 (en) | 2001-03-29 | 2003-05-06 | Merck & Co., Inc. | Preparation and isolation of indolocarbazole glycosides |
| AP2004003120A0 (en) * | 2002-03-26 | 2004-09-30 | Banyu Pharma Co Ltd | Combined use of antitumor indolopyrrolocarbazole derivatives and other antitumor agent |
| CA2398828A1 (en) | 2002-08-09 | 2004-02-09 | Merck & Co., Inc. | A pharmaceutical composition containing an indolopyrrolocarbazole derivative |
| EP1541582A1 (en) * | 2002-08-23 | 2005-06-15 | Banyu Pharmaceutical Co., Ltd. | Process for producing indolopyrrolocarbazole derivative |
| AU2003248103A1 (en) * | 2003-07-24 | 2005-02-14 | Banyu Pharmaceutical Co., Ltd | Indolopyrrolocarbazole derivative and antitumor agent |
| AU2004272457A1 (en) * | 2003-09-16 | 2005-03-24 | Banyu Pharmaceutical Co., Ltd. | Novel indolopyrrolocarbazole derivative with antitumor activity |
| US7169802B2 (en) | 2003-12-23 | 2007-01-30 | Cephalon, Inc. | Fused pyrrolocarbazoles |
| US7241779B2 (en) * | 2003-12-23 | 2007-07-10 | Cephalon, Inc. | Fused pyrrolocarbazoles |
| RU2255089C1 (ru) * | 2003-12-26 | 2005-06-27 | Закрытое акционерное общество "АСГЛ-Исследовательские Лаборатории" | Производные гликозидов индоло[2,3-а]пирроло[3,4-с]карбазол-5,7-дионов, обладающие цитотоксической и противоопухолевой активностью |
| ES2326459B1 (es) | 2008-04-08 | 2010-05-28 | Universidad De Oviedo | Indolocarbazoles glicosilados, su procedimiento de obtencion y sus usos. |
| JP2012509282A (ja) | 2008-11-19 | 2012-04-19 | セファロン、インク． | インダゾロ［５，４−ａ］ピロロ［３，４−ｃ］カルバゾール化合物の新しい形態 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4785085A (en) * | 1986-11-21 | 1988-11-15 | Bristol-Myers Company | Rebeccamycin analogs |
| DE4005969A1 (de) * | 1990-02-26 | 1991-08-29 | Boehringer Mannheim Gmbh | Neue trisubstituierte pyrrole, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten |
| IL97233A (en) * | 1990-03-06 | 1995-03-30 | Bristol Myers Squibb Co | Rebeccamycin analogs, their production and pharmaceutical compositions containing them |
| JPH0725787B2 (ja) * | 1990-03-06 | 1995-03-22 | ブリストル−マイヤーズ スクイブ カンパニー | 臭化物前駆物質物質供給によるレベカマイシン類似体 |
| WO1992018507A1 (en) * | 1991-04-11 | 1992-10-29 | Schering Corporation | Anti-tumor and anti-psoriatic agents |
-
1992
- 1992-11-20 NZ NZ245203A patent/NZ245203A/en not_active IP Right Cessation
- 1992-11-22 DZ DZ920145A patent/DZ1634A1/fr active
- 1992-11-23 AT AT92119904T patent/ATE130617T1/de not_active IP Right Cessation
- 1992-11-23 IL IL103844A patent/IL103844A/xx not_active IP Right Cessation
- 1992-11-23 ES ES92119904T patent/ES2079774T3/es not_active Expired - Lifetime
- 1992-11-23 DK DK92119904.8T patent/DK0545195T3/da active
- 1992-11-23 DE DE69206242T patent/DE69206242T2/de not_active Expired - Fee Related
- 1992-11-23 EP EP92119904A patent/EP0545195B1/en not_active Expired - Lifetime
- 1992-11-23 CA CA002083534A patent/CA2083534C/en not_active Expired - Fee Related
- 1992-11-24 JP JP4336560A patent/JP2629542B2/ja not_active Expired - Fee Related
- 1992-11-25 TW TW081109448A patent/TW224469B/zh active
- 1992-11-25 MY MYPI92002167A patent/MY114655A/en unknown
- 1992-11-26 AU AU29637/92A patent/AU650376B2/en not_active Ceased
- 1992-11-27 CZ CS19923508A patent/CZ287304B6/cs not_active IP Right Cessation
- 1992-11-27 FI FI925422A patent/FI106864B/fi active
- 1992-11-27 NO NO924593A patent/NO178929C/no not_active IP Right Cessation
- 1992-11-27 MX MX9206847A patent/MX9206847A/es unknown
- 1992-11-27 RO RO93-01067A patent/RO113469B1/ro unknown
- 1992-11-27 RU RU93050130A patent/RU2117671C1/ru not_active IP Right Cessation
- 1992-11-27 HU HU9203754A patent/HU9203754D0/hu unknown
- 1992-11-27 PL PL92304729A patent/PL171468B1/pl not_active IP Right Cessation
- 1992-11-27 HU HU9203754A patent/HU217611B/hu not_active IP Right Cessation
- 1992-11-27 YU YU102692A patent/YU48963B/sh unknown
- 1992-11-27 WO PCT/JP1992/001549 patent/WO1993011145A1/en not_active Ceased
- 1992-11-28 KR KR1019920022729A patent/KR100275976B1/ko not_active Expired - Fee Related
-
1993
- 1993-01-30 SA SA93130351A patent/SA93130351B1/ar unknown
- 1993-07-20 BG BG97970A patent/BG61036B1/bg unknown
-
1995
- 1995-06-08 HU HU95P/P00172P patent/HU211254A9/hu unknown
- 1995-12-22 GR GR950403667T patent/GR3018527T3/el unknown
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