MX360236B - Uso de marcadores en el diagnostico y tratamiento de cancer de prostata. - Google Patents
Uso de marcadores en el diagnostico y tratamiento de cancer de prostata.Info
- Publication number
- MX360236B MX360236B MX2015000008A MX2015000008A MX360236B MX 360236 B MX360236 B MX 360236B MX 2015000008 A MX2015000008 A MX 2015000008A MX 2015000008 A MX2015000008 A MX 2015000008A MX 360236 B MX360236 B MX 360236B
- Authority
- MX
- Mexico
- Prior art keywords
- prostate cancer
- markers
- level
- cancer
- prostata
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57555—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the prostate
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4742—Keratin; Cytokeratin
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La presente invención se refiere a un método para diagnosticar cáncer de próstata en un sujeto, caracterizado porque comprende: (1) determinar un nivel de uno o más marcadores relacionados con el cáncer de próstata que comprende queratina 19 en una muestra de suero del sujeto; y (2) comparar el nivel de uno o más marcadores relacionados con el cáncer de próstata en la muestra de suero con el nivel de uno o más de los marcadores relacionados con el cáncer de próstata en una muestra de control normal, en donde el nivel incrementado de queratina 19 en la muestra de suero en relación con la muestra de control normal es indicativo de cáncer de próstata en el sujeto.
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261665201P | 2012-06-27 | 2012-06-27 | |
| US201261672090P | 2012-07-16 | 2012-07-16 | |
| US201261673094P | 2012-07-18 | 2012-07-18 | |
| US201261702523P | 2012-09-18 | 2012-09-18 | |
| US201261718081P | 2012-10-24 | 2012-10-24 | |
| US201261718080P | 2012-10-24 | 2012-10-24 | |
| US201261718064P | 2012-10-24 | 2012-10-24 | |
| PCT/US2013/048373 WO2014004931A1 (en) | 2012-06-27 | 2013-06-27 | Use of markers in the diagnosis and treatment of prostate cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015000008A MX2015000008A (es) | 2015-04-10 |
| MX360236B true MX360236B (es) | 2018-10-26 |
Family
ID=49783880
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015000008A MX360236B (es) | 2012-06-27 | 2013-06-27 | Uso de marcadores en el diagnostico y tratamiento de cancer de prostata. |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US20140038838A1 (es) |
| EP (1) | EP2867375B1 (es) |
| JP (2) | JP6352909B2 (es) |
| KR (1) | KR20150023904A (es) |
| CN (1) | CN104583422A (es) |
| AU (1) | AU2013284448B2 (es) |
| BR (1) | BR112014032728A2 (es) |
| CA (1) | CA2877721A1 (es) |
| EA (1) | EA201492284A1 (es) |
| ES (1) | ES2720763T3 (es) |
| IL (1) | IL236482A0 (es) |
| MX (1) | MX360236B (es) |
| NZ (1) | NZ703411A (es) |
| SG (1) | SG11201408651TA (es) |
| WO (1) | WO2014004931A1 (es) |
Families Citing this family (15)
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|---|---|---|---|---|
| TWI596494B (zh) | 2012-03-05 | 2017-08-21 | Opko診斷法有限責任公司 | 預測前列腺癌風險及前列腺腺體體積之方法及裝置 |
| CN106061998B (zh) * | 2014-02-05 | 2020-12-11 | 弗吉瑞必欧诊断股份公司 | 用于检测恶性赘生性疾病的组合物和方法 |
| KR102505543B1 (ko) | 2014-03-28 | 2023-03-02 | 옵코 다이어그노스틱스, 엘엘씨 | 전립선암 진단에 관한 조성물 및 방법 |
| US12326453B2 (en) | 2014-03-28 | 2025-06-10 | Opko Diagnostics, Llc | Compositions and methods for active surveillance of prostate cancer |
| SG10202012249YA (en) | 2014-12-08 | 2021-01-28 | Berg Llc | Use of markers including filamin a in the diagnosis and treatment of prostate cancer |
| PT3253800T (pt) | 2015-03-27 | 2021-04-28 | Opko Diagnostics Llc | Padrões de antigénio da próstata e suas utilizações |
| CA3026342A1 (en) * | 2016-06-03 | 2017-12-07 | Etubics Corporation | Compositions and methods for tumor vaccination using prostate cancer-associated antigens |
| CA3030219A1 (en) * | 2016-07-07 | 2018-01-11 | Berg Llc | Lipid, protein, and metabolite markers for the diagnosis and treatment of prostate cancer |
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| KR102405789B1 (ko) * | 2018-08-24 | 2022-06-07 | 고려대학교 세종산학협력단 | 키누레닌 경로 대사체를 포함하는 전립선암 진단용 바이오마커 조성물 |
| CN109608537B (zh) * | 2018-12-12 | 2020-09-15 | 深圳市龙华区人民医院 | 基于前列腺癌干细胞标志物cd44的抗原表位多肽cd44-p2及其应用 |
| CN109608536B (zh) * | 2018-12-12 | 2020-09-15 | 深圳市龙华区人民医院 | 基于前列腺癌干细胞标志物cd44的抗原表位多肽cd44-p3及其应用 |
| KR102497196B1 (ko) * | 2020-09-08 | 2023-02-07 | (주)유로테크 | 전립선암 진단 점수 계산 방법 및 그 용도 |
| CN114134223B (zh) * | 2021-12-02 | 2022-10-11 | 青岛市中心血站 | 一种用于丙型肝炎病毒相关肝纤维化的血液检测试剂盒 |
| CN114460297A (zh) * | 2022-01-17 | 2022-05-10 | 珠海中科先进技术研究院有限公司 | 一种用于检测血液中循环前列腺上皮细胞的免疫荧光试剂盒及其使用方法 |
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2013
- 2013-06-27 NZ NZ703411A patent/NZ703411A/en not_active IP Right Cessation
- 2013-06-27 MX MX2015000008A patent/MX360236B/es active IP Right Grant
- 2013-06-27 BR BR112014032728A patent/BR112014032728A2/pt not_active IP Right Cessation
- 2013-06-27 EA EA201492284A patent/EA201492284A1/ru unknown
- 2013-06-27 KR KR1020157002289A patent/KR20150023904A/ko not_active Ceased
- 2013-06-27 CN CN201380045178.1A patent/CN104583422A/zh active Pending
- 2013-06-27 JP JP2015520541A patent/JP6352909B2/ja not_active Expired - Fee Related
- 2013-06-27 EP EP13809780.3A patent/EP2867375B1/en active Active
- 2013-06-27 WO PCT/US2013/048373 patent/WO2014004931A1/en not_active Ceased
- 2013-06-27 US US13/929,723 patent/US20140038838A1/en not_active Abandoned
- 2013-06-27 AU AU2013284448A patent/AU2013284448B2/en not_active Ceased
- 2013-06-27 ES ES13809780T patent/ES2720763T3/es active Active
- 2013-06-27 SG SG11201408651TA patent/SG11201408651TA/en unknown
- 2013-06-27 CA CA2877721A patent/CA2877721A1/en not_active Abandoned
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2014
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2016
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2017
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| AU2013284448B2 (en) | 2019-04-18 |
| HK1209792A1 (en) | 2016-04-08 |
| AU2013284448A1 (en) | 2015-01-22 |
| US20140038838A1 (en) | 2014-02-06 |
| JP2018163164A (ja) | 2018-10-18 |
| EP2867375B1 (en) | 2019-02-27 |
| EP2867375A4 (en) | 2016-06-01 |
| WO2014004931A1 (en) | 2014-01-03 |
| IL236482A0 (en) | 2015-02-26 |
| CN104583422A (zh) | 2015-04-29 |
| JP6352909B2 (ja) | 2018-07-04 |
| ES2720763T3 (es) | 2019-07-24 |
| US20160178632A1 (en) | 2016-06-23 |
| US20180031563A1 (en) | 2018-02-01 |
| KR20150023904A (ko) | 2015-03-05 |
| MX2015000008A (es) | 2015-04-10 |
| JP2015523569A (ja) | 2015-08-13 |
| NZ703411A (en) | 2017-09-29 |
| CA2877721A1 (en) | 2014-01-03 |
| EP2867375A1 (en) | 2015-05-06 |
| US9797905B2 (en) | 2017-10-24 |
| EA201492284A1 (ru) | 2015-11-30 |
| SG11201408651TA (en) | 2015-01-29 |
| JP6581247B2 (ja) | 2019-09-25 |
| BR112014032728A2 (pt) | 2017-11-28 |
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