MX354547B - Ensayos y métodos para seleccionar un regimen de tratamiento para un sujeto con depresión. - Google Patents
Ensayos y métodos para seleccionar un regimen de tratamiento para un sujeto con depresión.Info
- Publication number
- MX354547B MX354547B MX2014005786A MX2014005786A MX354547B MX 354547 B MX354547 B MX 354547B MX 2014005786 A MX2014005786 A MX 2014005786A MX 2014005786 A MX2014005786 A MX 2014005786A MX 354547 B MX354547 B MX 354547B
- Authority
- MX
- Mexico
- Prior art keywords
- subject
- depression
- biomarkers
- treatment regimen
- effectiveness
- Prior art date
Links
- 238000011269 treatment regimen Methods 0.000 title abstract 5
- 238000003556 assay Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 238000011282 treatment Methods 0.000 title 1
- 239000000090 biomarker Substances 0.000 abstract 6
- 239000000203 mixture Substances 0.000 abstract 6
- 239000000935 antidepressant agent Substances 0.000 abstract 4
- JVJFIQYAHPMBBX-FNORWQNLSA-N (E)-4-hydroxynon-2-enal Chemical compound CCCCCC(O)\C=C\C=O JVJFIQYAHPMBBX-FNORWQNLSA-N 0.000 abstract 2
- JVJFIQYAHPMBBX-UHFFFAOYSA-N HNE Natural products CCCCCC(O)C=CC=O JVJFIQYAHPMBBX-UHFFFAOYSA-N 0.000 abstract 2
- 101001013648 Homo sapiens Methionine synthase Proteins 0.000 abstract 2
- 101001116314 Homo sapiens Methionine synthase reductase Proteins 0.000 abstract 2
- 101000587058 Homo sapiens Methylenetetrahydrofolate reductase Proteins 0.000 abstract 2
- 102100031551 Methionine synthase Human genes 0.000 abstract 2
- 102100024614 Methionine synthase reductase Human genes 0.000 abstract 2
- 102100029684 Methylenetetrahydrofolate reductase Human genes 0.000 abstract 2
- 101001030849 Rhinella marina Mesotocin receptor Proteins 0.000 abstract 2
- 208000028552 Treatment-Resistant Depressive disease Diseases 0.000 abstract 2
- 238000005299 abrasion Methods 0.000 abstract 2
- 230000001430 anti-depressive effect Effects 0.000 abstract 2
- 229940005513 antidepressants Drugs 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000000994 depressogenic effect Effects 0.000 abstract 2
- 229920001971 elastomer Polymers 0.000 abstract 2
- 229940014144 folate Drugs 0.000 abstract 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 abstract 2
- 235000019152 folic acid Nutrition 0.000 abstract 2
- 239000011724 folic acid Substances 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 229920000620 organic polymer Polymers 0.000 abstract 2
- 230000002093 peripheral effect Effects 0.000 abstract 2
- 239000005060 rubber Substances 0.000 abstract 2
- 229940124834 selective serotonin reuptake inhibitor Drugs 0.000 abstract 2
- 239000012896 selective serotonin reuptake inhibitor Substances 0.000 abstract 2
- 229920002050 silicone resin Polymers 0.000 abstract 2
- 229920001169 thermoplastic Polymers 0.000 abstract 2
- 239000004416 thermosoftening plastic Substances 0.000 abstract 2
- RNFJDJUURJAICM-UHFFFAOYSA-N 2,2,4,4,6,6-hexaphenoxy-1,3,5-triaza-2$l^{5},4$l^{5},6$l^{5}-triphosphacyclohexa-1,3,5-triene Chemical compound N=1P(OC=2C=CC=CC=2)(OC=2C=CC=CC=2)=NP(OC=2C=CC=CC=2)(OC=2C=CC=CC=2)=NP=1(OC=1C=CC=CC=1)OC1=CC=CC=C1 RNFJDJUURJAICM-UHFFFAOYSA-N 0.000 abstract 1
- 229910052782 aluminium Inorganic materials 0.000 abstract 1
- 239000004411 aluminium Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 239000003063 flame retardant Substances 0.000 abstract 1
- 229920001187 thermosetting polymer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161559541P | 2011-11-14 | 2011-11-14 | |
| PCT/US2012/065084 WO2013074676A2 (en) | 2011-11-14 | 2012-11-14 | Assays and methods for selecting a treatment regimen for a subject with depression |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014005786A MX2014005786A (es) | 2014-08-27 |
| MX354547B true MX354547B (es) | 2018-03-09 |
Family
ID=47279072
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014005786A MX354547B (es) | 2011-11-14 | 2012-11-14 | Ensayos y métodos para seleccionar un regimen de tratamiento para un sujeto con depresión. |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9540691B2 (enExample) |
| EP (1) | EP2780467B1 (enExample) |
| JP (1) | JP6285865B2 (enExample) |
| KR (1) | KR102035877B1 (enExample) |
| CN (1) | CN104053785A (enExample) |
| AU (1) | AU2012340015B2 (enExample) |
| BR (1) | BR112014011491A2 (enExample) |
| CA (1) | CA2855640C (enExample) |
| IL (1) | IL232407B (enExample) |
| IN (1) | IN2014DN04226A (enExample) |
| MX (1) | MX354547B (enExample) |
| RU (1) | RU2622082C2 (enExample) |
| WO (1) | WO2013074676A2 (enExample) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104053785A (zh) * | 2011-11-14 | 2014-09-17 | 综合医院公司 | 为患有抑郁症的受试者选择治疗方案的测定法和方法 |
| KR20150131147A (ko) * | 2013-03-12 | 2015-11-24 | 네스텍 소시에테아노님 | 우울증을 갖는 대상을 위해 치료 섭생법을 선별하기 위한 검정법 및 방법 |
| US20140274981A1 (en) | 2013-03-15 | 2014-09-18 | Janssen Pharmaceutica Nv | Pharmaceutical composition of s-ketamine hydrochloride |
| US20150250813A1 (en) * | 2013-12-05 | 2015-09-10 | Buriva, LLC | Dietary supplement containing phospholipid-dha, folate, and n-acetyl-l-cysteine |
| US9610302B2 (en) * | 2013-12-05 | 2017-04-04 | Buriva, LLC. | Composition containing phospholipid-DHA and B vitamins |
| US9549937B2 (en) * | 2013-12-05 | 2017-01-24 | Burvia, LLC. | Composition containing phospholipid-DHA and folate |
| AU2015227296A1 (en) * | 2014-03-05 | 2016-09-08 | Takeda Pharmaceutical Company Limited | Method for treating depression and major depressive disorder |
| WO2015136446A1 (en) * | 2014-03-11 | 2015-09-17 | Nestec S.A. | Methods for selecting antidepressant drug therapy to treat depression |
| KR101588119B1 (ko) * | 2014-05-16 | 2016-01-25 | 동아대학교 산학협력단 | Ｓｌｃ6ａ3 유전자의 다형성 소위성과 이를 이용한 ｄｎａ 타이핑 키트 및 상기 유전자 관련 질병의 진단키트 |
| US10098854B2 (en) | 2014-08-13 | 2018-10-16 | Janssen Pharmaceutica Nv | Method for the treatment of depression |
| EP3193853A1 (en) | 2014-09-15 | 2017-07-26 | Janssen Pharmaceutica NV | VAL66MET (SNP rs6265) GENOTYPE SPECIFIC DOSING REGIMENS AND METHODS FOR THE TREATMENT OF DEPRESSION |
| CN105671130A (zh) * | 2014-11-18 | 2016-06-15 | 武汉白原科技有限公司 | 一种心理性格检测试剂盒和方法 |
| US20160203591A1 (en) * | 2015-01-09 | 2016-07-14 | Umm Al-Qura University | System and process for monitoring the quality of food in a refrigerator |
| CN104655705B (zh) * | 2015-02-12 | 2017-03-08 | 江苏省原子医学研究所 | 一种用毛细管电泳快速检测生物样本中儿茶酚氧甲基转移酶comt活性的方法 |
| CN104789668A (zh) * | 2015-04-10 | 2015-07-22 | 浙江博惠生物科技有限公司 | 一种叶酸代谢能力评估的检测位点rs1801394的检测PCR扩增引物和单碱基延伸引物 |
| US11122997B2 (en) | 2015-04-17 | 2021-09-21 | Mayo Foundation For Medical Education And Research | Modulating the aryl hydrocarbon receptor system to treat major depressive disorder |
| US20180137235A1 (en) * | 2015-04-28 | 2018-05-17 | Proove Biosciences, Inc. | System and method for processing genotype information relating to opioid risk |
| US20160332962A1 (en) | 2015-05-13 | 2016-11-17 | Janssen Pharmaceutica Nv | (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine |
| JP6974179B2 (ja) * | 2015-05-25 | 2021-12-01 | フーナン スカイワールド バイオテクノロジーズ コンパニー | Ｓ−アデノシルメチオニン、ｓ−アデノシルホモシステイン及びホモシステインを迅速かつ簡単に測定するための蛍光の使用 |
| US11313868B2 (en) | 2016-06-14 | 2022-04-26 | Board Of Regents, The University Of Texas System | Methods of detecting anti-folic acid antibodies and uses thereof |
| WO2018053605A1 (en) * | 2016-09-26 | 2018-03-29 | Precision Medicine Holdings Pty Ltd | Diagnosis, prognosis and treatment for schizophrenia and schizoaffective psychosis |
| CN107245527A (zh) * | 2017-07-25 | 2017-10-13 | 重庆京因生物科技有限责任公司 | Mtrr基因多态性快速检测的引物、分子信标、试剂盒及其检测方法 |
| US11399575B2 (en) * | 2017-08-02 | 2022-08-02 | Glaxosmithkline Consumer Healthcare Holdings (Us) Llc | Wearable device and application for behavioral support |
| US20200009081A1 (en) | 2017-09-13 | 2020-01-09 | Janssen Pharmaceutica N.V. | Delivery Of Esketamine For The Treatment Of Depression |
| SG11202005896WA (en) | 2017-12-22 | 2020-07-29 | Janssen Pharmaceuticals Inc | Esketamine for the treatment of depression |
| CN108251522B (zh) * | 2018-04-09 | 2020-11-27 | 江苏硕世生物科技股份有限公司 | 人类mthfr和mtrr基因检测试剂盒及其用途 |
| CN108642138B (zh) * | 2018-05-02 | 2021-11-30 | 广东药科大学 | 一种检测叶酸代谢相关基因遗传信息的方法及试剂盒 |
| CA3099344A1 (en) | 2018-05-03 | 2019-11-07 | Pierre L. DE ROCHEMONT | High speed / low power server farms and server networks |
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| CN108823299A (zh) * | 2018-06-11 | 2018-11-16 | 苏州艾达康医疗科技有限公司 | 一种抑郁症用药相关基因的检测方法及试剂盒 |
| JP2021534804A (ja) * | 2018-09-03 | 2021-12-16 | ビスビュー メディカル，インコーポレイテッド | 抗生物質感受性検査のための装置および方法 |
| EP3934632A4 (en) | 2019-03-05 | 2022-11-23 | Janssen Pharmaceuticals, Inc. | Esketamine for the treatment of depression |
| EP3969621A4 (en) | 2019-05-14 | 2023-01-25 | Prometheus Biosciences, Inc. | TL1A PATIENT SELECTION METHODS, SYSTEMS AND DEVICES |
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| CN110693507A (zh) * | 2019-08-30 | 2020-01-17 | 中国民用航空飞行学院 | 一种民航飞行学员心理健康测试和心理援助系统 |
| CN111351945B (zh) * | 2020-03-18 | 2021-04-23 | 东南大学 | 维生素d结合蛋白作为标志物在精神疾病抑郁症诊断中的应用 |
| AU2021244617A1 (en) | 2020-03-26 | 2022-11-10 | Migdalia FORT | Ultraviolet radiation treatments |
| WO2022115277A1 (en) * | 2020-11-24 | 2022-06-02 | Genomind, Inc. | Methods and systems for reporting patient-and drug-specific medical data |
| CN116103385B (zh) * | 2021-11-11 | 2024-11-15 | 深圳理工大学 | 一种预测抑郁障碍患者对治疗反应的基因诊断试剂盒和系统 |
| KR102925722B1 (ko) * | 2022-01-17 | 2026-02-10 | 서울대학교산학협력단 | 멀티오믹스 기반의 신경계 질환 분석 장치 및 방법 |
| KR102925724B1 (ko) * | 2022-01-17 | 2026-02-10 | 서울대학교산학협력단 | 게놈-대사체 통합 분석 기반의 만성신장질환 분석 장치 및 방법 |
| CN116298233A (zh) * | 2022-03-16 | 2023-06-23 | 昱言科技(北京)有限公司 | 用于诊断双相障碍的生物标记物 |
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| CN120847438B (zh) * | 2025-07-16 | 2026-02-03 | 江西众康中药饮片有限公司 | 药材辨识系统及方法 |
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| AU2012340015B2 (en) | 2017-09-21 |
| CN104053785A (zh) | 2014-09-17 |
| JP6285865B2 (ja) | 2018-02-28 |
| NZ624231A (en) | 2016-10-28 |
| IN2014DN04226A (enExample) | 2015-05-22 |
| EP2780467A2 (en) | 2014-09-24 |
| US9540691B2 (en) | 2017-01-10 |
| HK1202590A1 (en) | 2015-10-02 |
| WO2013074676A2 (en) | 2013-05-23 |
| KR102035877B1 (ko) | 2019-10-23 |
| CA2855640C (en) | 2020-03-10 |
| WO2013074676A3 (en) | 2013-08-15 |
| RU2014124121A (ru) | 2015-12-27 |
| JP2015508281A (ja) | 2015-03-19 |
| AU2012340015A1 (en) | 2014-05-22 |
| US20130172361A1 (en) | 2013-07-04 |
| US20130267523A1 (en) | 2013-10-10 |
| KR20140100524A (ko) | 2014-08-14 |
| MX2014005786A (es) | 2014-08-27 |
| US9546401B2 (en) | 2017-01-17 |
| IL232407A0 (en) | 2014-06-30 |
| EP2780467B1 (en) | 2018-10-17 |
| IL232407B (en) | 2019-03-31 |
| BR112014011491A2 (pt) | 2017-05-09 |
| RU2622082C2 (ru) | 2017-06-09 |
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