MX2019010189A - Polisulfato de pentosan, composicion farmaceutica y anticoagulante. - Google Patents
Polisulfato de pentosan, composicion farmaceutica y anticoagulante.Info
- Publication number
- MX2019010189A MX2019010189A MX2019010189A MX2019010189A MX2019010189A MX 2019010189 A MX2019010189 A MX 2019010189A MX 2019010189 A MX2019010189 A MX 2019010189A MX 2019010189 A MX2019010189 A MX 2019010189A MX 2019010189 A MX2019010189 A MX 2019010189A
- Authority
- MX
- Mexico
- Prior art keywords
- pentosan polysulfate
- pharmaceutically acceptable
- anticoagulant
- pharmaceutical composition
- acceptable salt
- Prior art date
Links
- 229940043138 pentosan polysulfate Drugs 0.000 title abstract 3
- 239000003146 anticoagulant agent Substances 0.000 title abstract 2
- 229940127219 anticoagulant drug Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 230000001858 anti-Xa Effects 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000012453 solvate Substances 0.000 abstract 2
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0057—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Xylans, i.e. xylosaccharide, e.g. arabinoxylan, arabinofuronan, pentosans; (beta-1,3)(beta-1,4)-D-Xylans, e.g. rhodymenans; Hemicellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7024—Esters of saccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/06—Use of macromolecular materials
- A61L33/08—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/14—Hemicellulose; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/14—Hemicellulose; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L97/00—Compositions of lignin-containing materials
- C08L97/02—Lignocellulosic material, e.g. wood, straw or bagasse
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Materials Engineering (AREA)
- Hematology (AREA)
- Polymers & Plastics (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Surgery (AREA)
- Birds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Cosmetics (AREA)
Abstract
La presente invención provee polisulfato de pentosan que tiene un peso molecular promedio en peso de 5000 o menos y un contenido de grupos acetilo de 0% a 2.0% en masa, o una sal farmacéuticamente aceptable del mismo, o un solvato farmacéuticamente aceptable del mismo. El polisulfato de pentosan de la presente invención, o una sal farmacéuticamente aceptable del mismo, o un solvato farmacéuticamente aceptable del mismo exhibe una actividad anti-Xa y una relación de actividad anti-Xa/anti-Ila, que son apropiadas para uso práctico, y es útil como una composición farmacéutica tal como un anticoagulante.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2017035916 | 2017-02-28 | ||
| JP2017166559A JP6281659B1 (ja) | 2017-02-28 | 2017-08-31 | ポリ硫酸ペントサン、医薬組成物及び抗凝固剤 |
| PCT/JP2018/007138 WO2018159580A1 (ja) | 2017-02-28 | 2018-02-27 | ポリ硫酸ペントサン、医薬組成物及び抗凝固剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2019010189A true MX2019010189A (es) | 2019-10-09 |
Family
ID=61231477
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019010189A MX2019010189A (es) | 2017-02-28 | 2018-02-27 | Polisulfato de pentosan, composicion farmaceutica y anticoagulante. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US11274165B2 (es) |
| EP (1) | EP3590971B1 (es) |
| JP (1) | JP6281659B1 (es) |
| KR (1) | KR102520754B1 (es) |
| CN (1) | CN110325553B (es) |
| AU (1) | AU2018229054B2 (es) |
| BR (1) | BR112019017527B1 (es) |
| CA (1) | CA3054533C (es) |
| ES (1) | ES2929538T3 (es) |
| HU (1) | HUE060518T2 (es) |
| MX (1) | MX2019010189A (es) |
| PL (1) | PL3590971T3 (es) |
| PT (1) | PT3590971T (es) |
| SG (1) | SG11201907938RA (es) |
| WO (1) | WO2018159580A1 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6225321B1 (ja) | 2016-08-31 | 2017-11-08 | 王子ホールディングス株式会社 | ポリ硫酸ペントサンの製造方法 |
| WO2018043667A1 (ja) | 2016-08-31 | 2018-03-08 | 王子ホールディングス株式会社 | 酸性キシロオリゴ糖の製造方法及び酸性キシロオリゴ糖 |
| JP6281659B1 (ja) | 2017-02-28 | 2018-02-21 | 王子ホールディングス株式会社 | ポリ硫酸ペントサン、医薬組成物及び抗凝固剤 |
| SG10201913607WA (en) | 2017-05-31 | 2020-03-30 | Oji Holdings Corp | Moisturizing topical preparation |
| BR112020004787A2 (pt) | 2017-09-12 | 2020-09-24 | Oji Holdings Corporation | polissulfato de pentosano, composição farmacêutica, anticoagulante, e, método para produzir polissulfato de pentosano |
| PL3730521T3 (pl) * | 2017-12-20 | 2023-10-09 | Oji Holdings Corporation | Polisiarczan pentozanu i lek zawierający polisiarczan pentozanu |
| AU2018437600B2 (en) * | 2018-08-20 | 2022-11-17 | Reqmed Company, Ltd. | Novel pentosan polysulfate sodium preparation |
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| JPS4843100A (es) * | 1971-09-30 | 1973-06-22 | ||
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| FR2538404B1 (es) | 1982-12-28 | 1985-08-23 | Anic Spa | |
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| JPS60112708A (ja) | 1983-11-24 | 1985-06-19 | Maruho Kk | 皮膚用保湿剤 |
| FR2572731B1 (fr) | 1984-11-07 | 1987-03-06 | Sanofi Sa | Nouveaux sulfates de xylanes de bas poids moleculaires, leur procede de preparation et leur activite antithrombotique et hypolipemiante par voie orale |
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| US5672334A (en) | 1991-01-16 | 1997-09-30 | Access Pharmaceuticals, Inc. | Invivo agents comprising cationic metal chelators with acidic saccharides and glycosaminoglycans |
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| CN106832020A (zh) | 2015-12-04 | 2017-06-13 | 长春工业大学 | 一种玉米秸秆戊聚糖硫酸酯的制备工艺 |
| CN105907896B (zh) | 2016-05-16 | 2019-11-12 | 中国科学院广州能源研究所 | 一种利用木质纤维原料联产高浓度木糖和低聚木糖的方法 |
| WO2018043667A1 (ja) * | 2016-08-31 | 2018-03-08 | 王子ホールディングス株式会社 | 酸性キシロオリゴ糖の製造方法及び酸性キシロオリゴ糖 |
| JP6225321B1 (ja) | 2016-08-31 | 2017-11-08 | 王子ホールディングス株式会社 | ポリ硫酸ペントサンの製造方法 |
| JP6281659B1 (ja) * | 2017-02-28 | 2018-02-21 | 王子ホールディングス株式会社 | ポリ硫酸ペントサン、医薬組成物及び抗凝固剤 |
-
2017
- 2017-08-31 JP JP2017166559A patent/JP6281659B1/ja active Active
-
2018
- 2018-02-27 PL PL18761900.2T patent/PL3590971T3/pl unknown
- 2018-02-27 CN CN201880013926.0A patent/CN110325553B/zh active Active
- 2018-02-27 EP EP18761900.2A patent/EP3590971B1/en active Active
- 2018-02-27 US US16/489,074 patent/US11274165B2/en active Active
- 2018-02-27 CA CA3054533A patent/CA3054533C/en active Active
- 2018-02-27 AU AU2018229054A patent/AU2018229054B2/en active Active
- 2018-02-27 ES ES18761900T patent/ES2929538T3/es active Active
- 2018-02-27 BR BR112019017527-0A patent/BR112019017527B1/pt active IP Right Grant
- 2018-02-27 HU HUE18761900A patent/HUE060518T2/hu unknown
- 2018-02-27 WO PCT/JP2018/007138 patent/WO2018159580A1/ja unknown
- 2018-02-27 MX MX2019010189A patent/MX2019010189A/es unknown
- 2018-02-27 KR KR1020197024908A patent/KR102520754B1/ko active IP Right Grant
- 2018-02-27 SG SG11201907938RA patent/SG11201907938RA/en unknown
- 2018-02-27 PT PT187619002T patent/PT3590971T/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2929538T3 (es) | 2022-11-30 |
| CA3054533A1 (en) | 2018-09-07 |
| US11274165B2 (en) | 2022-03-15 |
| CN110325553B (zh) | 2021-10-08 |
| BR112019017527A2 (pt) | 2020-03-31 |
| WO2018159580A1 (ja) | 2018-09-07 |
| BR112019017527B1 (pt) | 2024-03-12 |
| JP6281659B1 (ja) | 2018-02-21 |
| HUE060518T2 (hu) | 2023-03-28 |
| EP3590971B1 (en) | 2022-10-12 |
| KR102520754B1 (ko) | 2023-04-11 |
| CN110325553A (zh) | 2019-10-11 |
| CA3054533C (en) | 2024-05-28 |
| EP3590971A1 (en) | 2020-01-08 |
| AU2018229054A1 (en) | 2019-09-12 |
| JP2018141120A (ja) | 2018-09-13 |
| SG11201907938RA (en) | 2019-09-27 |
| PL3590971T3 (pl) | 2023-01-23 |
| KR20190120216A (ko) | 2019-10-23 |
| US20200062867A1 (en) | 2020-02-27 |
| EP3590971A4 (en) | 2020-12-09 |
| PT3590971T (pt) | 2022-11-29 |
| AU2018229054B2 (en) | 2021-09-16 |
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