MX2011008119A - Derivado de acido hialuronico polisulfatado de bajo peso molecular, y medicamento que contiene el mismo. - Google Patents

Derivado de acido hialuronico polisulfatado de bajo peso molecular, y medicamento que contiene el mismo.

Info

Publication number
MX2011008119A
MX2011008119A MX2011008119A MX2011008119A MX2011008119A MX 2011008119 A MX2011008119 A MX 2011008119A MX 2011008119 A MX2011008119 A MX 2011008119A MX 2011008119 A MX2011008119 A MX 2011008119A MX 2011008119 A MX2011008119 A MX 2011008119A
Authority
MX
Mexico
Prior art keywords
molecular
low
hyaluronic acid
acid derivative
polysulfated hyaluronic
Prior art date
Application number
MX2011008119A
Other languages
English (en)
Inventor
Fumitaka Goto
Yoko Sakamoto
Takahiro Tomoyasu
Yusuke Kato
Takao Taki
Takashi Hayashi
Yasuo Koga
Kazuaki Kakehi
Hiroaki Asai
Naohiro Hayashi
Satoshi Shimizu
Satoru Nakazato
Junji Takaba
Atsushi Azuma
Wakako Hirano
Kazunari Izumi
Minoru Kashimoto
Masaru Nishida
Original Assignee
Otsuka Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Chemical Co Ltd filed Critical Otsuka Chemical Co Ltd
Publication of MX2011008119A publication Critical patent/MX2011008119A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Otolaryngology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)

Abstract

Se describe un derivado de ácido hialurónico polisulfatado de bajo peso molecular útil para la prevención y/o el tratamiento de una enfermedad alérgica; la presente invención se refiere también a un agente para la prevención y/o el tratamiento de una enfermedad alérgica seleccionada de polinosis, rinitis alérgica, conjuntivitis alérgica, dermatitis atópica y asma, representado por la fórmula general (lA) o (IB) siguiente: (ver fórmula (IA o IB)) en donde n representa un número de 0 a 15; y cada R's representa independientemente un átomo de hidrógeno o un grupo SO3H, etc.
MX2011008119A 2009-02-02 2010-02-01 Derivado de acido hialuronico polisulfatado de bajo peso molecular, y medicamento que contiene el mismo. MX2011008119A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2009021820 2009-02-02
PCT/JP2010/000583 WO2010087207A1 (ja) 2009-02-02 2010-02-01 低分子量多硫酸化ヒアルロン酸誘導体及びこれを含有する医薬

Publications (1)

Publication Number Publication Date
MX2011008119A true MX2011008119A (es) 2011-08-24

Family

ID=42395469

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011008119A MX2011008119A (es) 2009-02-02 2010-02-01 Derivado de acido hialuronico polisulfatado de bajo peso molecular, y medicamento que contiene el mismo.

Country Status (20)

Country Link
US (1) US8993536B2 (es)
EP (1) EP2392579B1 (es)
JP (2) JP4884559B2 (es)
KR (1) KR101678429B1 (es)
CN (1) CN102300870B (es)
AR (1) AR075224A1 (es)
BR (1) BRPI1007325A2 (es)
CA (1) CA2750188C (es)
CO (1) CO6362026A2 (es)
ES (1) ES2610240T3 (es)
HK (1) HK1159642A1 (es)
IL (1) IL213323A (es)
MX (1) MX2011008119A (es)
MY (1) MY160359A (es)
NZ (1) NZ594854A (es)
RU (1) RU2519781C2 (es)
SG (2) SG2014006985A (es)
TW (1) TWI539955B (es)
UA (1) UA105781C2 (es)
WO (1) WO2010087207A1 (es)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2010010904A (es) 2008-04-04 2010-11-04 Univ Utah Res Found Eteres de glicosaminoglicosano semisinteticos alquilados, y metodos para elaborarlos y usarlos.
EP2397484A1 (en) * 2010-06-11 2011-12-21 Immunovo B.V. Trisaccharide derivates, and their use as adjuvants
JP2012046511A (ja) * 2010-07-30 2012-03-08 Otsuka Chem Co Ltd 低分子量多硫酸化ヒアルロン酸誘導体を含有する医薬
US9522162B2 (en) 2011-03-23 2016-12-20 University Of Utah Research Foundation Methods for treating or preventing urological inflammation
JP5871500B2 (ja) * 2011-06-20 2016-03-01 公益財団法人先端医療振興財団 α−Ｋｌｏｔｈｏ／ＦＧＦ２３複合体形成阻害化合物
TW201400494A (zh) * 2012-03-22 2014-01-01 Otsuka Pharma Co Ltd 寡糖化合物之製造方法
CN102579478A (zh) * 2012-03-30 2012-07-18 济南康众医药科技开发有限公司 玻璃酸钠在制备药物中的应用
JP2014047155A (ja) * 2012-08-30 2014-03-17 Tottori Univ 保護硫酸化オリゴ糖化合物及びその製造方法
SE538503C2 (en) 2014-11-11 2016-08-16 Tx Medic Ab New dextran sulfate
ITUB20155623A1 (it) * 2015-11-16 2017-05-16 Fidia Farm Spa Processo migliorato per la produzione di HA solfatato di elevata purezza
KR102559743B1 (ko) 2016-08-31 2023-07-25 오지 홀딩스 가부시키가이샤 산성 자일로올리고당의 제조 방법 및 산성 자일로올리고당
JP6225321B1 (ja) 2016-08-31 2017-11-08 王子ホールディングス株式会社 ポリ硫酸ペントサンの製造方法
US11337994B2 (en) 2016-09-15 2022-05-24 University Of Utah Research Foundation In situ gelling compositions for the treatment or prevention of inflammation and tissue damage
JP6281659B1 (ja) * 2017-02-28 2018-02-21 王子ホールディングス株式会社 ポリ硫酸ペントサン、医薬組成物及び抗凝固剤
WO2018165656A1 (en) 2017-03-10 2018-09-13 The University Of North Carolina At Chapel Hill Short-acting heparin-based anticoagulant compounds and methods
CA3065747A1 (en) 2017-05-31 2018-12-06 Oji Holdings Corporation Moisturizing composition comprising pentosan polysulfate
WO2019010216A1 (en) 2017-07-03 2019-01-10 The University Of North Carolina At Chapel Hill ENZYMATIC SYNTHESIS OF HOMOGENEOUS CHONDROITIN SULFATE OLIGOSACCHARIDES
MX2020002726A (es) 2017-09-12 2020-07-20 Oji Holdings Corp Polisulfato de pentosan y metodo para producir polisulfato de pentosan.
WO2019090203A1 (en) 2017-11-03 2019-05-09 The University Of North Carolina At Chapel Hill Sulfated oligosaccharides having anti-inflammatory activity
AU2018387999B2 (en) 2017-12-20 2021-06-17 Oji Holdings Corporation Pentosan polysulfate and medicine containing pentosan polysulfate
CN112437667B (zh) * 2018-06-20 2024-05-28 北卡罗来纳大学查珀尔希尔分校 细胞保护方法和组合物
WO2024072942A2 (en) 2022-09-29 2024-04-04 Adora Animal Health Corporation Skin penetrating formulations of sulfated glycosaminoglycans and fragments derived therefrom for the treatment of pain and other medical conditions

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08277224A (ja) * 1995-02-07 1996-10-22 Shiseido Co Ltd 抗炎症剤
DE69621528T2 (de) 1995-02-07 2003-01-16 Shiseido Co. Ltd., Tokio/Tokyo Anti-inflamatorische agenzien
JPH10195107A (ja) * 1997-01-10 1998-07-28 Shiseido Co Ltd オリゴ硫酸化ヒアルロン酸
JPH11147901A (ja) 1997-11-19 1999-06-02 Maruho Co Ltd カリクレイン−キニン系阻害剤
JPH11269077A (ja) * 1998-03-19 1999-10-05 Maruho Co Ltd ホスホリパーゼａ２阻害用医薬組成物
US6689748B1 (en) 1998-04-08 2004-02-10 Theoharis C. Theoharides Method of treating mast cell activation-induced diseases with a proteoglycan
JPH11335288A (ja) 1998-05-20 1999-12-07 Maruho Co Ltd アレルギー性疾患の予防または治療薬
WO2000069917A1 (fr) * 1999-05-18 2000-11-23 Maruho Kabushikikaisha Compositions medicinales destinees a inhiber le systeme kallikreine-kinine ou la phospholipase a¿2?
JP2004059506A (ja) * 2002-07-29 2004-02-26 Taisho Pharmaceut Co Ltd セレクチン及びケモカインに作用する過硫酸化オリゴ糖
FR2845686B1 (fr) * 2002-10-10 2013-08-30 Aventis Pharma Sa Melanges de polysaccharides derives d'heparine, leur preparation et les compositions pharmaceutiques les contenant
US20040171819A1 (en) 2002-10-10 2004-09-02 Aventis Pharma S.A. Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
ATE397006T1 (de) * 2004-08-05 2008-06-15 Ivax Drug Res Inst Ltd Polysulfatierte glykoside und salze davon

Also Published As

Publication number Publication date
IL213323A0 (en) 2011-07-31
US20110281819A1 (en) 2011-11-17
US8993536B2 (en) 2015-03-31
CO6362026A2 (es) 2012-01-20
JP2011168591A (ja) 2011-09-01
EP2392579A1 (en) 2011-12-07
NZ594854A (en) 2013-03-28
MY160359A (en) 2017-02-28
TWI539955B (zh) 2016-07-01
CA2750188C (en) 2016-11-29
TW201032814A (en) 2010-09-16
SG2014006985A (en) 2014-04-28
AR075224A1 (es) 2011-03-16
EP2392579A4 (en) 2012-09-26
CA2750188A1 (en) 2010-08-05
ES2610240T3 (es) 2017-04-26
KR20110117118A (ko) 2011-10-26
KR101678429B1 (ko) 2016-11-22
RU2519781C2 (ru) 2014-06-20
CN102300870B (zh) 2014-12-03
IL213323A (en) 2014-12-31
EP2392579B1 (en) 2016-11-23
JPWO2010087207A1 (ja) 2012-08-02
HK1159642A1 (zh) 2012-08-03
JP4884559B2 (ja) 2012-02-29
CN102300870A (zh) 2011-12-28
BRPI1007325A2 (pt) 2019-09-24
JP5554738B2 (ja) 2014-07-23
SG173470A1 (en) 2011-09-29
RU2011136250A (ru) 2013-03-10
AU2010209200A1 (en) 2011-06-30
UA105781C2 (uk) 2014-06-25
WO2010087207A1 (ja) 2010-08-05

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