NO20064659L - Nye kvarterniserte quinuklidin-estere - Google Patents

Nye kvarterniserte quinuklidin-estere

Info

Publication number
NO20064659L
NO20064659L NO20064659A NO20064659A NO20064659L NO 20064659 L NO20064659 L NO 20064659L NO 20064659 A NO20064659 A NO 20064659A NO 20064659 A NO20064659 A NO 20064659A NO 20064659 L NO20064659 L NO 20064659L
Authority
NO
Norway
Prior art keywords
compounds
new
quinuclidine esters
urological
respiratory
Prior art date
Application number
NO20064659A
Other languages
English (en)
Inventor
Maria Dolors Fernandez Forner
Maria Prat Quinones
Maria Antonia Buil Albero
Original Assignee
Almirall Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Lab filed Critical Almirall Lab
Publication of NO20064659L publication Critical patent/NO20064659L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Abstract

Nye kinuklidinderivater og farmasøytiske sammensetninger omfattende disse. Forbindelser med formel (I), hvori de ulike substituenter og/eller radikaler har verdiene definert i kravene. Oppfinnelsen angår også en fremgangsmåte for fremstilling av nevnte forbindelser, til farmasøytiske sammensetninger som omfatter disse, så vel som til kombinasjoner av nevnte forbindelser med andre forbindelser, som er aktive i behandlingen av respiratorisk, urologisk eller gastrointestinale forstyrrelser eller sykdommer. Endelig angår oppfinnelsen også anvendelse av forbindelsene med formel (I) for behandling av respiratoriske, urologiske eller gasttointestinale forstyrrelser eller sykdommer.
NO20064659A 2004-03-15 2006-10-13 Nye kvarterniserte quinuklidin-estere NO20064659L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200400638A ES2239546B1 (es) 2004-03-15 2004-03-15 Nuevos esteres de quinuclidina cuaternizados.
PCT/EP2005/002523 WO2005090342A1 (en) 2004-03-15 2005-03-10 New quaternized quinuclidine esters

Publications (1)

Publication Number Publication Date
NO20064659L true NO20064659L (no) 2006-12-13

Family

ID=34955916

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20064659A NO20064659L (no) 2004-03-15 2006-10-13 Nye kvarterniserte quinuklidin-estere

Country Status (31)

Country Link
US (1) US20080214600A1 (no)
EP (1) EP1725552B1 (no)
JP (1) JP2007529444A (no)
KR (1) KR20070003940A (no)
CN (1) CN1930158A (no)
AR (1) AR048004A1 (no)
AT (1) ATE399166T1 (no)
AU (1) AU2005223310A1 (no)
BR (1) BRPI0508177A (no)
CA (1) CA2560157A1 (no)
CY (1) CY1108324T1 (no)
DE (1) DE602005007714D1 (no)
DK (1) DK1725552T3 (no)
EC (1) ECSP066770A (no)
ES (2) ES2239546B1 (no)
HK (1) HK1101855A1 (no)
HR (1) HRP20080338T3 (no)
IL (1) IL177341A0 (no)
MY (1) MY142036A (no)
NO (1) NO20064659L (no)
NZ (1) NZ548583A (no)
PE (1) PE20060005A1 (no)
PL (1) PL1725552T3 (no)
PT (1) PT1725552E (no)
RS (1) RS50566B (no)
RU (1) RU2382041C2 (no)
SI (1) SI1725552T1 (no)
TW (1) TW200604196A (no)
UA (1) UA88634C2 (no)
WO (1) WO2005090342A1 (no)
ZA (1) ZA200605931B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
GB0424284D0 (en) * 2004-11-02 2004-12-01 Novartis Ag Organic compounds
ES2298049B1 (es) * 2006-07-21 2009-10-20 Laboratorios Almirall S.A. Procedimiento para fabricar bromuro de 3(r)-(2-hidroxi-2,2-ditien-2-ilacetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo (2.2.2) octano.
KR20090110353A (ko) * 2007-02-15 2009-10-21 아젠터 디스커버리 리미티드 Ｍ３ 무스카린 수용체로서의 헤테로시클릭 유도체
RU2480458C2 (ru) 2007-09-07 2013-04-27 Тереванс, Инк. Гуанидинсодержащие соединения, применимые в качестве антагонистов мускариновых рецепторов
CA2608561A1 (en) * 2007-10-29 2009-04-29 Carl Paluszkiewicz Motorcycle wind deflector accessory support
EP2222637A1 (en) 2007-12-14 2010-09-01 Theravance, Inc. Amidine-containing compounds useful as muscarinic receptor antagonists
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
US20090326004A1 (en) 2008-06-03 2009-12-31 Ranbaxy Laboratories Limited Muscarinic receptor antagonists
CA2758100C (en) 2009-04-09 2017-08-29 Novartis Ag Process for preparing pyrrolidinium salts
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
CN104837828B (zh) * 2012-12-05 2017-07-18 奇斯药制品公司 作为pde4‑抑制剂的苯基乙基吡啶衍生物
CN103755698A (zh) * 2014-01-06 2014-04-30 万特制药(海南)有限公司 一锅法制备阿地溴铵的工艺
CN103755699A (zh) * 2014-01-06 2014-04-30 万特制药(海南)有限公司 一种2-羟基-2,2-二噻吩-2-基乙酸-1-氮杂二环[2,2,2]辛-3(r)-基酯制备方法
KR101511090B1 (ko) 2014-04-24 2015-04-10 고려대학교 산학협력단 염증성 질환의 예방 또는 치료용 약학 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1219606A (en) * 1968-07-15 1971-01-20 Rech S Et D Applic Scient Soge Quinuclidinol derivatives and preparation thereof
US4843074A (en) * 1988-05-17 1989-06-27 Marion Laboratories, Inc. 1-azabicyclo[2.2.2]octan-3-yl 2-aryl-3-azacyclo-2-hydroxypropionates and their quaternary salts
ES2165768B1 (es) * 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
BR0116624A (pt) * 2000-12-28 2003-12-23 Almirall Prodesfarma Ag Composto, processo para produzir o mesmo, composição farmacêutica, uso do composto ou da composição farmacêutica, e, produto de combinação
US7361668B2 (en) * 2001-10-17 2008-04-22 Ucb, S.A. Quinuclidine derivatives processes for preparing them and their uses as m2 and/or m3 muscarinic receptor inhibitors
ES2204295B1 (es) * 2002-07-02 2005-08-01 Almirall Prodesfarma, S.A. Nuevos derivados de quinuclidina-amida.
AR044134A1 (es) * 2003-05-02 2005-08-24 Novartis Ag Derivados de quinuclidina, metodo de preparacion y composiciones farmaceuticas.

Also Published As

Publication number Publication date
UA88634C2 (en) 2009-11-10
PE20060005A1 (es) 2006-01-28
ES2239546A1 (es) 2005-09-16
WO2005090342A1 (en) 2005-09-29
TW200604196A (en) 2006-02-01
HK1101855A1 (en) 2007-10-26
DE602005007714D1 (de) 2008-08-07
US20080214600A1 (en) 2008-09-04
EP1725552A1 (en) 2006-11-29
ES2239546B1 (es) 2006-12-01
BRPI0508177A (pt) 2007-08-07
PT1725552E (pt) 2008-09-18
CY1108324T1 (el) 2014-02-12
AU2005223310A1 (en) 2005-09-29
SI1725552T1 (sl) 2008-10-31
NZ548583A (en) 2010-05-28
RS50566B (sr) 2010-05-07
ZA200605931B (en) 2007-11-28
ES2307168T3 (es) 2008-11-16
EP1725552B1 (en) 2008-06-25
JP2007529444A (ja) 2007-10-25
HRP20080338T3 (en) 2008-07-31
RU2382041C2 (ru) 2010-02-20
CN1930158A (zh) 2007-03-14
CA2560157A1 (en) 2005-09-29
ATE399166T1 (de) 2008-07-15
DK1725552T3 (da) 2008-10-13
AR048004A1 (es) 2006-03-15
PL1725552T3 (pl) 2008-12-31
RU2006136085A (ru) 2008-04-27
KR20070003940A (ko) 2007-01-05
IL177341A0 (en) 2006-12-10
MY142036A (en) 2010-08-16
ECSP066770A (es) 2006-11-16

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