MX2016001247A - MATRICES DERIVED FROM SOFT ACELLULAR FABRIC AND METHODS TO PREPARE THE SAME. - Google Patents

MATRICES DERIVED FROM SOFT ACELLULAR FABRIC AND METHODS TO PREPARE THE SAME.

Info

Publication number
MX2016001247A
MX2016001247A MX2016001247A MX2016001247A MX2016001247A MX 2016001247 A MX2016001247 A MX 2016001247A MX 2016001247 A MX2016001247 A MX 2016001247A MX 2016001247 A MX2016001247 A MX 2016001247A MX 2016001247 A MX2016001247 A MX 2016001247A
Authority
MX
Mexico
Prior art keywords
acellular
soft tissue
tissue
matrix
methods
Prior art date
Application number
MX2016001247A
Other languages
English (en)
Inventor
Chen Huang Yen-
Ivery Asia
Choi Bryan
SCHILLING Benjamin
Dan Ngo Manh-
Original Assignee
Musculoskeletal Transplant Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US201361860043P priority Critical
Application filed by Musculoskeletal Transplant Found filed Critical Musculoskeletal Transplant Found
Priority to PCT/US2014/048797 priority patent/WO2015017500A1/en
Publication of MX2016001247A publication Critical patent/MX2016001247A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/35Fat tissue; Adipocytes; Stromal cells; Connective tissues
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/40Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking

Abstract

Una matriz derivada de tejido suave acelular incluye un tejido colagenoso que ha sido deslipidado y descelularizado. El tejido adiposo está entre los tejidos suaves que son adecuados para manufacturar una matriz derivada de tejido suave acelular. Las células tejidogénicas exógenas y otros factores biológicamente activos se pueden agregar a la matriz acelular. La matriz acelular se puede proporcionar como partículas, una suspensión espesa, una pasta, un gel o en alguna otra forma. La matriz acelular se puede proporcionar como un andamio tridimensional que ha sido reconstituido a partir de partículas del tejido tridimensional. El andamio tridimensional puede tener la configuración de una cualidad anatómica y puede servir como una plantilla para la reparación o el reemplazo de tejido. Un método para hacer una matriz derivada de tejido suave acelular incluye los pasos que consisten en retirar lípido del tejido suave por medio de la extracción con solvente y la descelularización química del tejido suave.A matrix derived from soft acellular tissue includes a collagenous tissue that has been slipped and decellularized. Adipose tissue is among the soft tissues that are suitable for manufacturing a matrix derived from acellular soft tissue. Exogenous tissue cells and other biologically active factors can be added to the acellular matrix. The acellular matrix can be provided as particles, a thick suspension, a paste, a gel or in some other form. The acellular matrix can be provided as a three-dimensional scaffold that has been reconstituted from three-dimensional tissue particles. The three-dimensional scaffolding can have the configuration of an anatomical quality and can serve as a template for tissue repair or replacement. One method of making a matrix derived from acellular soft tissue includes the steps of removing lipid from soft tissue by solvent extraction and chemical decellularization of soft tissue.
MX2016001247A 2013-07-30 2014-07-30 MATRICES DERIVED FROM SOFT ACELLULAR FABRIC AND METHODS TO PREPARE THE SAME. MX2016001247A (es)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US201361860043P true 2013-07-30 2013-07-30
PCT/US2014/048797 WO2015017500A1 (en) 2013-07-30 2014-07-30 Acellular soft tissue-derived matrices and methods for preparing same

Publications (1)

Publication Number Publication Date
MX2016001247A true MX2016001247A (es) 2016-08-17

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016001247A MX2016001247A (es) 2013-07-30 2014-07-30 MATRICES DERIVED FROM SOFT ACELLULAR FABRIC AND METHODS TO PREPARE THE SAME.

Country Status (6)

Country Link
US (4) US20150037436A1 (es)
EP (1) EP3027235A1 (es)
AU (1) AU2014296259B2 (es)
CA (1) CA2919374C (es)
MX (1) MX2016001247A (es)
WO (1) WO2015017500A1 (es)

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