MX2015011688A - Moduladores benzoimidazol-2-il pirimidinas del receptor h4 de histamina. - Google Patents

Moduladores benzoimidazol-2-il pirimidinas del receptor h4 de histamina.

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Publication number
MX2015011688A
MX2015011688A MX2015011688A MX2015011688A MX2015011688A MX 2015011688 A MX2015011688 A MX 2015011688A MX 2015011688 A MX2015011688 A MX 2015011688A MX 2015011688 A MX2015011688 A MX 2015011688A MX 2015011688 A MX2015011688 A MX 2015011688A
Authority
MX
Mexico
Prior art keywords
benzoimidazol
receptor
histamine
modulators
pyrimidine
Prior art date
Application number
MX2015011688A
Other languages
English (en)
Inventor
Stefan Horns
Susanne Lochner
Magali B Hickey
Matteo Conza
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of MX2015011688A publication Critical patent/MX2015011688A/es

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Abstract

Benzoimidazol-2-il pirimidinas, métodos de purificación para las mismas, y composiciones farmacéuticas y métodos para el tratamiento de estados de enfermedad, trastornos, y afecciones mediados por la actividad del receptor H4, que incluyen alergia, asma, enfermedades autoinmunitarias y prurito.
MX2015011688A 2013-03-06 2014-03-06 Moduladores benzoimidazol-2-il pirimidinas del receptor h4 de histamina. MX2015011688A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361773706P 2013-03-06 2013-03-06
US201361776260P 2013-03-11 2013-03-11
US201361784909P 2013-03-14 2013-03-14
PCT/US2014/021130 WO2014138368A1 (en) 2013-03-06 2014-03-06 Benzoimidazol-2-yl pyrimidine modulators of the histamine h4 receptor

Publications (1)

Publication Number Publication Date
MX2015011688A true MX2015011688A (es) 2015-12-07

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MX2015011688A MX2015011688A (es) 2013-03-06 2014-03-06 Moduladores benzoimidazol-2-il pirimidinas del receptor h4 de histamina.

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US (4) US8859575B2 (es)
EP (2) EP3660011A1 (es)
JP (1) JP6471103B2 (es)
KR (1) KR102230383B1 (es)
CN (1) CN105025898B (es)
AU (1) AU2014225675B2 (es)
BR (1) BR112015021463A8 (es)
CA (1) CA2903737C (es)
CL (1) CL2015002434A1 (es)
CR (1) CR20150435A (es)
CY (1) CY1122545T1 (es)
DK (1) DK2964229T3 (es)
DO (1) DOP2016000027A (es)
EA (1) EA201591648A1 (es)
ES (1) ES2773543T3 (es)
GT (1) GT201500243A (es)
HK (1) HK1218513A1 (es)
HR (1) HRP20200253T1 (es)
HU (1) HUE047681T2 (es)
IL (1) IL240247B (es)
JO (1) JO3516B1 (es)
LT (1) LT2964229T (es)
MX (1) MX2015011688A (es)
MY (1) MY180726A (es)
NZ (1) NZ710640A (es)
PE (1) PE20151536A1 (es)
PH (1) PH12015501731A1 (es)
PL (1) PL2964229T3 (es)
PT (1) PT2964229T (es)
RS (1) RS59909B1 (es)
SA (1) SA515360981B1 (es)
SG (1) SG11201507117XA (es)
SI (1) SI2964229T1 (es)
TW (1) TWI617554B (es)
UA (1) UA118754C2 (es)
UY (1) UY35370A (es)
WO (1) WO2014138368A1 (es)
ZA (1) ZA201507351B (es)

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US9371311B2 (en) 2008-06-30 2016-06-21 Janssen Pharmaceutica Nv Benzoimidazol-2-yl pyrimidine derivatives
UY35370A (es) 2013-03-06 2014-09-30 Janssen Pharmaceutica Nv Moduladores benzoimidazol-2-il pirimidina del receptor de histamina h4
WO2014152537A1 (en) 2013-03-14 2014-09-25 Janssen Pharmaceutica Nv P2x7 modulators
TWI627174B (zh) 2013-03-14 2018-06-21 比利時商健生藥品公司 Ｐ２ｘ７調控劑
JO3773B1 (ar) 2013-03-14 2021-01-31 Janssen Pharmaceutica Nv معدلات p2x7
EP2970271B1 (en) 2013-03-14 2017-11-08 Janssen Pharmaceutica NV P2x7 modulators
ES2714048T3 (es) 2014-09-12 2019-05-24 Janssen Pharmaceutica Nv Moduladores de P2X7
JP6827113B2 (ja) 2017-01-21 2021-02-10 広州白雲山漢方現代薬業有限公司Ｇｕａｎｇｚｈｏｕ Ｈａｎｆａｎｇ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｃｏ．，Ｌｔｄ． シェーグレン症候群の治療におけるペオニフロリン−６’−ｏ−ベンゼンスルホン酸の使用
EP3856179A1 (en) 2018-09-28 2021-08-04 Janssen Pharmaceutica N.V. Monoacylglycerol lipase modulators
EP3856178A1 (en) 2018-09-28 2021-08-04 Janssen Pharmaceutica NV Monoacylglycerol lipase modulators
US11839663B2 (en) 2019-09-30 2023-12-12 Janssen Pharmaceutica Nv Radiolabelled MGL pet ligands
JP2023518511A (ja) 2020-03-26 2023-05-01 ヤンセン ファーマシューティカ エヌ．ベー． モノアシルグリセロールリパーゼ調節因子

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