MD3455258T2 - Metode de tratament al cancerului de piele prin administrarea unui inhibitor PD-1 - Google Patents
Metode de tratament al cancerului de piele prin administrarea unui inhibitor PD-1 Download PDFInfo
- Publication number
- MD3455258T2 MD3455258T2 MDE20190333T MDE20190333T MD3455258T2 MD 3455258 T2 MD3455258 T2 MD 3455258T2 MD E20190333 T MDE20190333 T MD E20190333T MD E20190333 T MDE20190333 T MD E20190333T MD 3455258 T2 MD3455258 T2 MD 3455258T2
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- antibody
- tumor
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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- C—CHEMISTRY; METALLURGY
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-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Cell Biology (AREA)
- Neurology (AREA)
- Botany (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662335743P | 2016-05-13 | 2016-05-13 | |
| US201662340142P | 2016-05-23 | 2016-05-23 | |
| US201662348546P | 2016-06-10 | 2016-06-10 | |
| US201662350305P | 2016-06-15 | 2016-06-15 | |
| US201662364920P | 2016-07-21 | 2016-07-21 | |
| US201662374020P | 2016-08-12 | 2016-08-12 | |
| US201762451274P | 2017-01-27 | 2017-01-27 | |
| PCT/US2017/032408 WO2017197263A1 (en) | 2016-05-13 | 2017-05-12 | Methods of treating skin cancer by administering a pd-1 inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MD3455258T2 true MD3455258T2 (ro) | 2022-02-28 |
Family
ID=58800911
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDE20190333T MD3455258T2 (ro) | 2016-05-13 | 2017-05-12 | Metode de tratament al cancerului de piele prin administrarea unui inhibitor PD-1 |
| MDE20220619T MD3932951T2 (ro) | 2016-05-13 | 2017-05-12 | Metode de tratament al cancerului de piele prin administrarea inhibitorului PD-1 |
| MDE20190335T MD3455259T2 (ro) | 2016-05-13 | 2017-05-12 | Combinație de anticorpi anti-PD-1 și radiație pentru tratarea cancerului |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDE20220619T MD3932951T2 (ro) | 2016-05-13 | 2017-05-12 | Metode de tratament al cancerului de piele prin administrarea inhibitorului PD-1 |
| MDE20190335T MD3455259T2 (ro) | 2016-05-13 | 2017-05-12 | Combinație de anticorpi anti-PD-1 și radiație pentru tratarea cancerului |
Country Status (32)
| Country | Link |
|---|---|
| US (4) | US20170327567A1 (https=) |
| EP (4) | EP3455258B1 (https=) |
| JP (4) | JP6999577B2 (https=) |
| KR (5) | KR102470294B1 (https=) |
| CN (4) | CN116407627A (https=) |
| AU (3) | AU2017264955B2 (https=) |
| BR (1) | BR112018073291A2 (https=) |
| CA (2) | CA3023985A1 (https=) |
| CL (1) | CL2018003207A1 (https=) |
| CY (1) | CY1124901T1 (https=) |
| DK (3) | DK3932951T5 (https=) |
| ES (3) | ES2899954T3 (https=) |
| FI (2) | FI3932951T3 (https=) |
| HR (3) | HRP20220014T1 (https=) |
| HU (3) | HUE061417T2 (https=) |
| IL (4) | IL302924B2 (https=) |
| LT (2) | LT3932951T (https=) |
| MD (3) | MD3455258T2 (https=) |
| MX (4) | MX2018013848A (https=) |
| MY (2) | MY208872A (https=) |
| NZ (2) | NZ788452A (https=) |
| PH (1) | PH12018502263A1 (https=) |
| PL (3) | PL3932951T3 (https=) |
| PT (3) | PT3455258T (https=) |
| RS (3) | RS62783B1 (https=) |
| SG (2) | SG11201809554VA (https=) |
| SI (3) | SI3932951T1 (https=) |
| SM (2) | SMT202200015T1 (https=) |
| TW (4) | TWI910495B (https=) |
| UA (1) | UA124151C2 (https=) |
| WO (2) | WO2017197259A1 (https=) |
| ZA (2) | ZA201807050B (https=) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX383464B (es) | 2015-07-13 | 2025-03-14 | Cytomx Therapeutics Inc | Anticuerpos anti-pd-1, anticuerpos anti-pd-1 activables, y métodos de uso de los mismos. |
| EP3740506A1 (en) * | 2018-01-16 | 2020-11-25 | Bristol-Myers Squibb Company | Methods of treating cancer with antibodies against tim3 |
| SG11202007590TA (en) | 2018-02-13 | 2020-09-29 | Merck Sharp & Dohme | Methods for treating cancer with anti-pd-1 antibodies |
| EP3775258A4 (en) | 2018-03-28 | 2022-01-26 | Board of Regents, The University of Texas System | IDENTIFICATION OF EPIGENETIC ALTERATIONS IN DNA ISOLATED FROM EXOSOMES |
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