SG11201809554VA - Methods of treating skin cancer by administering a pd-1 inhibitor - Google Patents

Methods of treating skin cancer by administering a pd-1 inhibitor

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Publication number
SG11201809554VA
SG11201809554VA SG11201809554VA SG11201809554VA SG11201809554VA SG 11201809554V A SG11201809554V A SG 11201809554VA SG 11201809554V A SG11201809554V A SG 11201809554VA SG 11201809554V A SG11201809554V A SG 11201809554VA SG 11201809554V A SG11201809554V A SG 11201809554VA
Authority
SG
Singapore
Prior art keywords
international
tarrytown
regeneron
methods
saw mill
Prior art date
Application number
SG11201809554VA
Inventor
Israel Lowy
Tasha Sims
Matthew Fury
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of SG11201809554VA publication Critical patent/SG11201809554VA/en

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    • A61K39/39541Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 16 November 2017 (16.11.2017) WIPO I PCT omit VIII Hot 0 Oil mom VIII 10110111110 oimIE (10) International Publication Number WO 2017/197263 Al (51) International Patent Classification: C07K 16/28 (2006.01) A61N 5/10 (2006.01) A61N 5/00 (2006.01) (21) International Application Number: PCT/US2017/032408 TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). (22) International Filing Date: Published: 12 May 2017 (12.05.2017) with international search report (Art. 21(3)) (25) Filing Language: English with sequence listing part of description (Rule 5.2(a)) (26) Publication Language: English (30) Priority Data: 62/335,743 13 May 2016 (13.05.2016) US 62/340,142 23 May 2016 (23.05.2016) US 62/348,546 10 June 2016 (10.06.2016) US 62/350,305 15 June 2016 (15.06.2016) US 62/364,920 21 July 2016 (21.07.2016) US 62/374,020 12 August 2016 (12.08.2016) US 62/451,274 27 January 2017 (27.01.2017) US (71) Applicant: REGENERON PHARMACEUTICALS, INC. [US/US]; 777 Old Saw Mill River Road, Tarrytown, NY 10591 (US). (72) Inventors: LOWY, Israel; c/o Regeneron Pharmaceuti- cals, Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591 (US). SIMS, Tasha, N.; c/o Regeneron Pharmaceu- ticals, Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591 (US). FURY, Matthew, G.; c/o Regeneron Pharma- ceuticals, Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591 (US). (74) Agent: KOWALCHYK, Katherine, M.; Merchant & Gould P.C., P.O. Box 2903, Minneapolis, MN 55402-0903 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, N 1-1 (54) Title: METHODS OF TREATING SKIN CANCER BY ADMINISTERING A PD-1 INHIBITOR (57) : The present disclosure provides methods for treating, reducing the severity, or inhibiting the growth of cancer (e.g., skin O cancer). The methods of the present disclosure comprise administering to a subject in need thereof a therapeutically effective amount of \" a programmed death 1 (PD-1) antagonist (e.g., an anti-PD-1 antibody). In certain embodiments, the skin cancer is cutaneous squamous 0 cell carcinoma or basal cell carcinoma.
SG11201809554VA 2016-05-13 2017-05-12 Methods of treating skin cancer by administering a pd-1 inhibitor SG11201809554VA (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201662335743P 2016-05-13 2016-05-13
US201662340142P 2016-05-23 2016-05-23
US201662348546P 2016-06-10 2016-06-10
US201662350305P 2016-06-15 2016-06-15
US201662364920P 2016-07-21 2016-07-21
US201662374020P 2016-08-12 2016-08-12
US201762451274P 2017-01-27 2017-01-27
PCT/US2017/032408 WO2017197263A1 (en) 2016-05-13 2017-05-12 Methods of treating skin cancer by administering a pd-1 inhibitor

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