MA35432B1 - Composé pour le traitement et la prophylaxie de la maladie du virus respiratoire syncytial - Google Patents

Composé pour le traitement et la prophylaxie de la maladie du virus respiratoire syncytial

Info

Publication number
MA35432B1
MA35432B1 MA36815A MA36815A MA35432B1 MA 35432 B1 MA35432 B1 MA 35432B1 MA 36815 A MA36815 A MA 36815A MA 36815 A MA36815 A MA 36815A MA 35432 B1 MA35432 B1 MA 35432B1
Authority
MA
Morocco
Prior art keywords
compound
prophylaxis
treatment
respiratory syncytial
syncytial virus
Prior art date
Application number
MA36815A
Other languages
English (en)
Inventor
Li Chen
Lichun Feng
Song Feng
Lu Gao
Tao Guo
Mengwei Huang
Chungen Liang
Yongfu Liu
Lisha Wang
Jason Christopher Wong
Jim Zhen Wu
Xihan Wu
Hongying Yun
Xiufang Zheng
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MA35432B1 publication Critical patent/MA35432B1/fr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)

Abstract

L'invention concerne un composé de formule (i), ainsi qu'un sel pharmaceutiquement acceptable de celui-ci, où r
MA36815A 2011-08-11 2014-03-11 Composé pour le traitement et la prophylaxie de la maladie du virus respiratoire syncytial MA35432B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2011078258 2011-08-11
CN2012078439 2012-07-10
PCT/EP2012/065499 WO2013020993A1 (fr) 2011-08-11 2012-08-08 Composé pour le traitement et la prophylaxie de la maladie du virus respiratoire syncytial

Publications (1)

Publication Number Publication Date
MA35432B1 true MA35432B1 (fr) 2014-09-01

Family

ID=46651492

Family Applications (1)

Application Number Title Priority Date Filing Date
MA36815A MA35432B1 (fr) 2011-08-11 2014-03-11 Composé pour le traitement et la prophylaxie de la maladie du virus respiratoire syncytial

Country Status (21)

Country Link
US (2) US8871756B2 (fr)
EP (1) EP2742039B1 (fr)
JP (1) JP5746793B2 (fr)
KR (1) KR101570627B1 (fr)
CN (1) CN103717589B (fr)
AU (1) AU2012293644B2 (fr)
BR (1) BR112014003198B1 (fr)
CA (1) CA2842123C (fr)
CL (1) CL2014000311A1 (fr)
CO (1) CO6852080A2 (fr)
CR (1) CR20140026A (fr)
EA (1) EA023262B1 (fr)
EC (1) ECSP14013199A (fr)
ES (1) ES2552016T3 (fr)
HK (1) HK1196131A1 (fr)
IL (1) IL230458A (fr)
MA (1) MA35432B1 (fr)
MX (1) MX349881B (fr)
MY (1) MY184306A (fr)
PE (1) PE20142148A1 (fr)
WO (1) WO2013020993A1 (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR099134A1 (es) * 2014-01-24 2016-06-29 Hoffmann La Roche Procedimiento para la preparación de n-[(3-aminooxetán-3-il)metil]-2-(1,1-dioxo-3,5-dihidro-1,4-benzotiazepín-4-il)-6-metil-quinazolín-4-amina
US9266835B2 (en) * 2014-02-27 2016-02-23 Janssen Pharmaceutica Nv Quinoline derivatives useful as CB-1 inverse agonists
US9464055B2 (en) * 2014-02-27 2016-10-11 Janssen Pharmaceutica Nv Quinoline derivatives useful as CB-1 inverse agonists
CN105726488B (zh) * 2014-12-08 2020-10-20 上海爱科百发生物医药技术有限公司 含有呼吸道合胞病毒抑制剂的肠溶微丸及其制备方法
CN104529802A (zh) * 2014-12-13 2015-04-22 西安近代化学研究所 一种合成n,n′-双取代氟代丙二酰胺化合物的方法
CN104860954B (zh) * 2015-04-20 2018-05-04 南京天印健华医药科技有限公司 一种苯酯螺吡咯烷类化合物及其制备方法
EP3298017B1 (fr) 2015-05-20 2019-08-14 H. Hoffnabb-La Roche Ag Composés pour le traitement d'une amyotrophie spinale
EP3322704B1 (fr) * 2015-07-16 2019-11-27 H. Hoffnabb-La Roche Ag Forme crystalline de la 4-quinazolinamine n-[(3-amino-3-oxétanyl)méthyl]-2-(2,3-dihydro-1,1-dioxido-1,4-benzothiazépin-4(5h)-yl)-6-méthyl pour le traitement des infections par le virus respiratoire syncytial (vrs)
WO2017080967A1 (fr) 2015-11-12 2017-05-18 F. Hoffmann-La Roche Ag Compositions pour le traitement d'une amyotrophie spinale
CN108137579B (zh) 2015-12-10 2022-01-07 豪夫迈·罗氏有限公司 桥连哌啶衍生物
IL281633B (en) 2015-12-10 2022-07-01 Ptc Therapeutics Inc Methods for treating Huntington's disease
CN109715612B (zh) 2016-07-14 2022-09-16 克林提克斯医药股份有限公司 促生长素抑制素调节剂及其用途
EP3634953B1 (fr) 2017-06-05 2024-01-03 PTC Therapeutics, Inc. Composés permettant de traiter la maladie de huntington
CA3067591A1 (fr) 2017-06-28 2019-01-03 Ptc Therapeutics, Inc. Procedes de traitement de la maladie de huntington
US11395822B2 (en) 2017-06-28 2022-07-26 Ptc Therapeutics, Inc. Methods for treating Huntington's disease
CA3094703A1 (fr) 2018-03-27 2019-10-03 Ptc Therapeutics, Inc. Composes pour le traitement de la maladie de huntington
WO2020005873A1 (fr) 2018-06-27 2020-01-02 Ptc Therapeutics, Inc. Composés hétérocycliques et hétéroaryles pour le traitement de la maladie de huntington
US11685746B2 (en) 2018-06-27 2023-06-27 Ptc Therapeutics, Inc. Heteroaryl compounds for treating Huntington's disease
JP7520816B2 (ja) 2018-09-06 2024-07-23 シダラ セラピューティクス インコーポレーテッド ウイルス感染症の治療のための組成物及び方法
JP7248255B2 (ja) * 2019-01-29 2023-03-29 シャンドン スアンズ ファーマ カンパニー，リミテッド ヘキソングルコキナーゼ阻害剤およびその使用
EP4028392A1 (fr) * 2019-09-09 2022-07-20 Cidara Therapeutics, Inc. Compositions et méthodes pour le traitement du virus respiratoire syncytial
GB201915273D0 (en) * 2019-10-22 2019-12-04 Reviral Ltd Pharmaceutical compounds
JP7357157B2 (ja) * 2019-10-31 2023-10-05 シャンハイ アーク バイオファーマスゥ－ティカル カンパニー リミテッド 呼吸器合胞体ウイルス融合タンパク質阻害剤組成物及びそれを用いてｒｓｖ感染を治療及び予防する方法
GB201915932D0 (en) * 2019-11-01 2019-12-18 Reviral Ltd Pharmaceutical compounds
CN113149977A (zh) * 2020-01-22 2021-07-23 苏州爱科百发生物医药技术有限公司 一类呼吸道合胞病毒抑制剂的合成与用途
CN111518055A (zh) * 2020-05-16 2020-08-11 西安都创医药科技有限公司 一种苯并硫氮杂卓氧化物的制备方法及其制备的产品及其应用
CN111620838A (zh) * 2020-05-16 2020-09-04 西安都创医药科技有限公司 一种氯代苯并硫氮杂卓化合物的制备方法及其制备的产品及其应用
CN111548325A (zh) * 2020-05-16 2020-08-18 西安都创医药科技有限公司 一种卤代苯并硫氮杂卓化合物的制备方法及其制备的产品及其应用
CN111574475B (zh) * 2020-06-03 2022-09-20 西安都创医药科技有限公司 卤代苯并硫杂卓氧化物的制备方法及其制备的产品及其应用
MX2023002761A (es) 2020-09-09 2023-04-03 Crinetics Pharmaceuticals Inc Formulaciones de un modulador de somatostatina.
CN113234085A (zh) * 2021-04-26 2021-08-10 无锡合全药业有限公司 一种2-氧杂-6-氮杂螺[3.4]辛烷-8-基氨基甲酸叔丁酯的合成方法
CN118239945A (zh) * 2022-12-22 2024-06-25 甫康（上海）健康科技有限责任公司 一种苯并硫氮杂卓类化合物及其制备方法与用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4044136A (en) * 1972-09-09 1977-08-23 Pfizer Inc. Aminoquinazoline therapeutic agents
GB1383409A (en) * 1972-09-09 1974-02-12 Pfizer Ltd Derivatives of 2-amino- and 4-amino-quinazoline and pharmaceutical compositions containing them
US5874438A (en) * 1996-10-11 1999-02-23 Bayer Aktiengesellschaft 2,2'-bridged bis-2,4-diaminoquinazolines
US6774134B2 (en) * 2000-12-20 2004-08-10 Bristol-Myers Squibb Company Heterocyclic substituted 2-methyl-benzimidazole antiviral agents
AU2004305039A1 (en) * 2003-12-12 2005-07-07 Qtl Biosystems Llc Metal ion mediated fluorescence superquenching assays, kits and reagents
WO2005061513A1 (fr) * 2003-12-24 2005-07-07 Biota Scientific Management Pty Ltd Agents polycycliques pour le traitement d'infections par le virus syncytial respiratoire
WO2008033466A2 (fr) * 2006-09-14 2008-03-20 Combinatorx (Singapore) Pre. Ltd. Compositions et procédés pour le traitement de maladies virales

Also Published As

Publication number Publication date
EP2742039A1 (fr) 2014-06-18
CN103717589B (zh) 2016-08-17
AU2012293644A1 (en) 2014-01-30
EA201490419A1 (ru) 2014-05-30
US8871756B2 (en) 2014-10-28
EP2742039B1 (fr) 2015-09-16
CN103717589A (zh) 2014-04-09
IL230458A0 (en) 2014-03-31
WO2013020993A1 (fr) 2013-02-14
US20130196974A1 (en) 2013-08-01
KR101570627B1 (ko) 2015-11-19
MY184306A (en) 2021-03-31
EA023262B1 (ru) 2016-05-31
KR20140045590A (ko) 2014-04-16
IL230458A (en) 2015-11-30
JP5746793B2 (ja) 2015-07-08
AU2012293644B2 (en) 2017-05-25
MX349881B (es) 2017-08-16
ECSP14013199A (es) 2014-03-31
JP2014521709A (ja) 2014-08-28
PE20142148A1 (es) 2015-01-03
CR20140026A (es) 2014-05-12
HK1196131A1 (zh) 2014-12-05
MX2014001481A (es) 2014-04-30
CA2842123C (fr) 2020-10-06
CL2014000311A1 (es) 2014-10-17
USRE49481E1 (en) 2023-04-04
CO6852080A2 (es) 2014-01-30
NZ620079A (en) 2016-06-24
ES2552016T3 (es) 2015-11-25
CA2842123A1 (fr) 2013-02-14
BR112014003198B1 (pt) 2020-10-13
BR112014003198A2 (pt) 2017-04-04

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