MX342153B - Compuestos para el tratamiento y profilaxis de enfermedad por el virus sincitial respiratorio. - Google Patents

Compuestos para el tratamiento y profilaxis de enfermedad por el virus sincitial respiratorio.

Info

Publication number
MX342153B
MX342153B MX2014003701A MX2014003701A MX342153B MX 342153 B MX342153 B MX 342153B MX 2014003701 A MX2014003701 A MX 2014003701A MX 2014003701 A MX2014003701 A MX 2014003701A MX 342153 B MX342153 B MX 342153B
Authority
MX
Mexico
Prior art keywords
prophylaxis
compounds
treatment
respiratory syncytial
syncytial virus
Prior art date
Application number
MX2014003701A
Other languages
English (en)
Other versions
MX2014003701A (es
Inventor
Liang Chungen
Wang Lisha
Yun Hongying
Zheng Xiufang
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX2014003701A publication Critical patent/MX2014003701A/es
Publication of MX342153B publication Critical patent/MX342153B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Se describe un compuesto de fórmula (I) (ver fórmula) también como una sal aceptable farmacéuticamente del mismo, en donde R1, R2 y X son como se definen en la descripción y en las reivindicaciones, que pueden ser usadas como medicamento.
MX2014003701A 2011-10-11 2012-10-08 Compuestos para el tratamiento y profilaxis de enfermedad por el virus sincitial respiratorio. MX342153B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2011080627 2011-10-11
PCT/EP2012/069813 WO2013053658A1 (en) 2011-10-11 2012-10-08 Compounds for the treatment and prophylaxis of respiratory syncytial virus disease

Publications (2)

Publication Number Publication Date
MX2014003701A MX2014003701A (es) 2015-04-14
MX342153B true MX342153B (es) 2016-09-15

Family

ID=47018191

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014003701A MX342153B (es) 2011-10-11 2012-10-08 Compuestos para el tratamiento y profilaxis de enfermedad por el virus sincitial respiratorio.

Country Status (10)

Country Link
US (1) US8604019B2 (es)
EP (1) EP2766370B1 (es)
JP (1) JP2014530225A (es)
KR (1) KR20140088555A (es)
BR (1) BR112014008783A2 (es)
CA (1) CA2847071A1 (es)
ES (1) ES2593059T3 (es)
MX (1) MX342153B (es)
RU (1) RU2014118330A (es)
WO (1) WO2013053658A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040175384A1 (en) * 2003-12-12 2004-09-09 Mohapatra Shyam S. Protein kinase C as a target for the treatment of respiratory syncytial virus
US10184942B2 (en) 2011-03-17 2019-01-22 University Of South Florida Natriuretic peptide receptor as a biomarker for diagnosis and prognosis of cancer
EA038819B1 (ru) 2013-08-21 2021-10-25 Алиос Биофарма, Инк. Противовирусные соединения
AR099134A1 (es) 2014-01-24 2016-06-29 Hoffmann La Roche Procedimiento para la preparación de n-[(3-aminooxetán-3-il)metil]-2-(1,1-dioxo-3,5-dihidro-1,4-benzotiazepín-4-il)-6-metil-quinazolín-4-amina
MA41614A (fr) 2015-02-25 2018-01-02 Alios Biopharma Inc Composés antiviraux
EP3322704B1 (en) 2015-07-16 2019-11-27 H. Hoffnabb-La Roche Ag Crystalline form of n-[(3-amino-3-oxetanyl)methyl]-2-(2,3-dihydro-1,1-dioxido-1,4-benzothiazepin-4(5h)-yl)-6-methyl-4-quinazolinamine for the treatment of respiratory syncytial virus (rsv) infections
BR112020006334A2 (pt) 2017-09-29 2020-09-24 Enanta Pharmaceuticals, Inc. combinação de agentes farmacêuticos como inibidores de rsv
CN117865910A (zh) * 2023-12-15 2024-04-12 山东盛安贝新材料有限公司南京分公司 一种齐瑞索韦中间体的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6774134B2 (en) * 2000-12-20 2004-08-10 Bristol-Myers Squibb Company Heterocyclic substituted 2-methyl-benzimidazole antiviral agents
US8598193B2 (en) * 2003-12-24 2013-12-03 Biota Scientific Management Pty Ltd. Polycyclic agents for the treatment of respiratory syncytial virus infections
WO2009008906A2 (en) * 2007-02-06 2009-01-15 The Trustees Of The University Of Pennsylvania Therapeutic compounds for blocking dna synthesis of pox viruses

Also Published As

Publication number Publication date
EP2766370A1 (en) 2014-08-20
HK1197058A1 (en) 2015-01-02
EP2766370B1 (en) 2016-08-03
BR112014008783A2 (pt) 2017-04-25
CA2847071A1 (en) 2013-04-18
JP2014530225A (ja) 2014-11-17
WO2013053658A1 (en) 2013-04-18
US20130090328A1 (en) 2013-04-11
MX2014003701A (es) 2015-04-14
RU2014118330A (ru) 2015-11-20
KR20140088555A (ko) 2014-07-10
US8604019B2 (en) 2013-12-10
ES2593059T3 (es) 2016-12-05

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