MX345264B - Derivado de azol. - Google Patents
Derivado de azol.Info
- Publication number
- MX345264B MX345264B MX2013010570A MX2013010570A MX345264B MX 345264 B MX345264 B MX 345264B MX 2013010570 A MX2013010570 A MX 2013010570A MX 2013010570 A MX2013010570 A MX 2013010570A MX 345264 B MX345264 B MX 345264B
- Authority
- MX
- Mexico
- Prior art keywords
- pharmaceutically acceptable
- acceptable salts
- formula
- azol
- derived
- Prior art date
Links
- PLIKAWJENQZMHA-UHFFFAOYSA-N 4-aminophenol Chemical compound NC1=CC=C(O)C=C1 PLIKAWJENQZMHA-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 201000004384 Alopecia Diseases 0.000 abstract 1
- 102100027913 Peptidyl-prolyl cis-trans isomerase FKBP1A Human genes 0.000 abstract 1
- 108010006877 Tacrolimus Binding Protein 1A Proteins 0.000 abstract 1
- 231100000360 alopecia Toxicity 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cosmetics (AREA)
Abstract
Se proveen compuestos novedosos que se unen a FKBP12 o sales farmacéuticamente aceptables de los mismos, así como nuevos agentes terapéuticos útiles en la prevención o tratamiento de alopecia que comprenden esos compuestos o sales farmacéuticamente aceptables de los mismos; de manera específica, se proveen compuestos representados por la fórmula (1) (Ver Formula) [en donde R1 representa ya sea la siguiente fórmula (2) o (3)] (Ver Formulas) o sales farmacéuticamente aceptables de los mismos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011056149 | 2011-03-15 | ||
| PCT/JP2012/056624 WO2012124750A1 (ja) | 2011-03-15 | 2012-03-15 | アゾール誘導体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013010570A MX2013010570A (es) | 2013-10-28 |
| MX345264B true MX345264B (es) | 2017-01-20 |
Family
ID=46830815
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013010570A MX345264B (es) | 2011-03-15 | 2012-03-15 | Derivado de azol. |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US9181229B2 (es) |
| EP (1) | EP2687524B1 (es) |
| JP (1) | JP5828339B2 (es) |
| KR (1) | KR101854949B1 (es) |
| CN (1) | CN103502240B (es) |
| AU (1) | AU2012229834B2 (es) |
| BR (1) | BR112013022710A2 (es) |
| CA (1) | CA2829746C (es) |
| CY (1) | CY1117011T1 (es) |
| DK (1) | DK2687524T3 (es) |
| ES (1) | ES2549559T3 (es) |
| HR (1) | HRP20151062T1 (es) |
| HU (1) | HUE027055T2 (es) |
| IL (1) | IL228319A (es) |
| ME (1) | ME02299B (es) |
| MX (1) | MX345264B (es) |
| MY (1) | MY162945A (es) |
| PH (1) | PH12013501897A1 (es) |
| PL (1) | PL2687524T3 (es) |
| PT (1) | PT2687524E (es) |
| RS (1) | RS54377B1 (es) |
| RU (1) | RU2573634C2 (es) |
| SG (1) | SG193461A1 (es) |
| SI (1) | SI2687524T1 (es) |
| SM (1) | SMT201500319B (es) |
| TW (1) | TWI534142B (es) |
| WO (1) | WO2012124750A1 (es) |
| ZA (1) | ZA201307179B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6020396B2 (ja) * | 2012-09-12 | 2016-11-02 | 大正製薬株式会社 | アゾール誘導体を含有する医薬 |
| CN107405340A (zh) * | 2015-02-25 | 2017-11-28 | 大正制药株式会社 | 毛发生长用外用组合物 |
| JP2017078044A (ja) * | 2015-10-21 | 2017-04-27 | 大正製薬株式会社 | 発毛剤組成物 |
| AU2020417293A1 (en) | 2020-01-03 | 2022-09-01 | Berg Llc | Polycyclic amides as UBE2K modulators for treating cancer |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR0159766B1 (ko) | 1989-10-16 | 1998-12-01 | 후지사와 토모키치로 | 양모제 조성물 |
| HU217621B (hu) | 1991-05-09 | 2000-03-28 | Vertex Pharmaceuticals Inc. | Eljárás új glioxaloil-pipekolinsav-észterek, származékaik és az ezeket tartalmazó gyógyszerkészítmények előállítására |
| US5859031A (en) | 1995-06-07 | 1999-01-12 | Gpi Nil Holdings, Inc. | Small molecule inhibitors of rotamase enzyme activity |
| US5945441A (en) | 1997-06-04 | 1999-08-31 | Gpi Nil Holdings, Inc. | Pyrrolidine carboxylate hair revitalizing agents |
| GB9804426D0 (en) | 1998-03-02 | 1998-04-29 | Pfizer Ltd | Heterocycles |
| AU743199B2 (en) | 1998-06-02 | 2002-01-24 | Bristol-Myers Squibb Company | Neurotrophic difluoroamide agents |
| WO1999062880A1 (en) | 1998-06-03 | 1999-12-09 | Gpi Nil Holdings, Inc. | N-linked sulfonamides of n-heterocyclic carboxylic acids or carboxylic acid isosteres |
| IL140042A0 (en) * | 1998-06-03 | 2002-02-10 | Guilford Pharm Inc | Carboxylic acids and carboxylic acid isosteres of n-heterocyclic compounds |
| GB9815696D0 (en) | 1998-07-20 | 1998-09-16 | Pfizer Ltd | Heterocyclics |
| US6228872B1 (en) | 1998-11-12 | 2001-05-08 | Bristol-Myers Squibb Company | Neurotrophic diamide and carbamate agents |
| RU2241709C2 (ru) * | 1999-07-09 | 2004-12-10 | Орто-Макнейл Фармасьютикал, Инк. | Производные азотсодержащих гетероциклических соединений и способ лечения расстройств, характеризующихся поражением нейронов |
| JP2001247569A (ja) | 1999-08-12 | 2001-09-11 | Japan Tobacco Inc | ピロリジン誘導体又はピペリジン誘導体及びその医薬用途 |
| US6818643B1 (en) | 1999-12-08 | 2004-11-16 | Bristol-Myers Squibb Company | Neurotrophic bicyclic diamides |
| JP4240978B2 (ja) | 2002-09-30 | 2009-03-18 | 大正製薬株式会社 | アリールオキシメチルオキサジアゾール誘導体 |
| JP4221989B2 (ja) | 2002-09-30 | 2009-02-12 | 大正製薬株式会社 | オキサジアゾール誘導体 |
| CA2673841A1 (en) | 2006-12-20 | 2008-06-26 | Taisho Pharmaceutical Co., Ltd. | Prophylactic or therapeutic agent for alopecia |
-
2012
- 2012-03-14 TW TW101108668A patent/TWI534142B/zh not_active IP Right Cessation
- 2012-03-15 PH PH1/2013/501897A patent/PH12013501897A1/en unknown
- 2012-03-15 HR HRP20151062TT patent/HRP20151062T1/hr unknown
- 2012-03-15 ES ES12757646.0T patent/ES2549559T3/es active Active
- 2012-03-15 US US14/004,997 patent/US9181229B2/en not_active Expired - Fee Related
- 2012-03-15 MY MYPI2013701644A patent/MY162945A/en unknown
- 2012-03-15 ME MEP-2015-201A patent/ME02299B/me unknown
- 2012-03-15 RS RS20150776A patent/RS54377B1/sr unknown
- 2012-03-15 CA CA2829746A patent/CA2829746C/en not_active Expired - Fee Related
- 2012-03-15 AU AU2012229834A patent/AU2012229834B2/en not_active Ceased
- 2012-03-15 MX MX2013010570A patent/MX345264B/es active IP Right Grant
- 2012-03-15 EP EP12757646.0A patent/EP2687524B1/en active Active
- 2012-03-15 RU RU2013145886/04A patent/RU2573634C2/ru not_active IP Right Cessation
- 2012-03-15 DK DK12757646.0T patent/DK2687524T3/en active
- 2012-03-15 PL PL12757646T patent/PL2687524T3/pl unknown
- 2012-03-15 BR BR112013022710A patent/BR112013022710A2/pt active Search and Examination
- 2012-03-15 WO PCT/JP2012/056624 patent/WO2012124750A1/ja not_active Ceased
- 2012-03-15 KR KR1020137024653A patent/KR101854949B1/ko not_active Expired - Fee Related
- 2012-03-15 JP JP2013504765A patent/JP5828339B2/ja not_active Expired - Fee Related
- 2012-03-15 SI SI201230334T patent/SI2687524T1/sl unknown
- 2012-03-15 CN CN201280013162.8A patent/CN103502240B/zh not_active Expired - Fee Related
- 2012-03-15 PT PT127576460T patent/PT2687524E/pt unknown
- 2012-03-15 HU HUE12757646A patent/HUE027055T2/en unknown
- 2012-03-15 SG SG2013069182A patent/SG193461A1/en unknown
-
2013
- 2013-09-09 IL IL228319A patent/IL228319A/en active IP Right Grant
- 2013-09-25 ZA ZA2013/07179A patent/ZA201307179B/en unknown
-
2015
- 2015-12-08 CY CY20151101118T patent/CY1117011T1/el unknown
- 2015-12-21 SM SM201500319T patent/SMT201500319B/it unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2020011449A (es) | Oxiesteroles y metodos de uso de los mismos. | |
| EA201590296A1 (ru) | Дейтерированный ибрутиниб | |
| CO6480927A2 (es) | Derivados de imidazolin-2-ona 1,3-disustituida como inhibidores de cyp17. | |
| CR20140525A (es) | Compuestos de N-alquiltriazol como antagonistas de LPAR | |
| EA201492023A1 (ru) | Регуляторы пути комплемента и их применение | |
| EA201401054A1 (ru) | N-циклиламиды в качестве нематоцидов | |
| EA201492287A1 (ru) | Дейтерированные производные руксолитиниба | |
| MX361499B (es) | Baricitinib deuterado. | |
| EA201690020A1 (ru) | Применение производных пиразолопиридина для лечения рака мочевого пузыря | |
| EA201490919A1 (ru) | Производные бетулина | |
| BR112015000704A2 (pt) | imidazotriazinacarbonitrilas úteis como inibidores de quinase | |
| ECSP13012362A (es) | Derivados de indolizina, su procedimiento de preparación | |
| MX2021005052A (es) | Oxiesteroles y métodos de uso de los mismos. | |
| EA201591634A1 (ru) | Дигидропиридопиримидиновые соединения | |
| BR112014028042A2 (pt) | inibidores de nampt | |
| GB201209587D0 (en) | Therapeutic compounds | |
| EA201591024A1 (ru) | Димерные соединения | |
| EA201600619A1 (ru) | Хромен и 1,1а, 2,7в-тетрагидроциклопропа[с]хромен пиридопиразиндионы в качестве модулятора гамма-секретазы | |
| UY33907A (es) | Derivados de pirazol microbicidas | |
| PH12015501429A1 (en) | Herbicidal composition | |
| PH12015501146A1 (en) | Hydantoin derivative | |
| EA201990313A1 (ru) | Производное триазолопиразинона, пригодное в качестве ингибитора фдэ1 человека | |
| BR112013027395A2 (pt) | inibidores de 17alfa-hidroxilase/c17,20-liase | |
| CY1117011T1 (el) | Παραγωγα αζολιου | |
| UA109804C2 (xx) | 2-метоксипіридин-4-ільні похідні |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |