MA26057A1 - Appareil et procédé de perçage de peau par microdents - Google Patents

Appareil et procédé de perçage de peau par microdents

Info

Publication number
MA26057A1
MA26057A1 MA27151A MA27151A MA26057A1 MA 26057 A1 MA26057 A1 MA 26057A1 MA 27151 A MA27151 A MA 27151A MA 27151 A MA27151 A MA 27151A MA 26057 A1 MA26057 A1 MA 26057A1
Authority
MA
Morocco
Prior art keywords
impact
microprotrusion member
stratum corneum
skin
microdents
Prior art date
Application number
MA27151A
Other languages
English (en)
Inventor
Michel J N Cormier
Peter E Daddona
Richard L Keenan
Weiqi Lin
James A Matriano
Ahmad P Samiee
Joseph C Trautman
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22906027&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA26057(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alza Corp filed Critical Alza Corp
Publication of MA26057A1 publication Critical patent/MA26057A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/20Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/20Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205Vaccinating by means of needles or other puncturing devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14507Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/150022Source of blood for capillary blood or interstitial fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150274Manufacture or production processes or steps for blood sampling devices
    • A61B5/150282Manufacture or production processes or steps for blood sampling devices for piercing elements, e.g. blade, lancet, canula, needle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150801Means for facilitating use, e.g. by people with impaired vision; means for indicating when used correctly or incorrectly; means for alarming
    • A61B5/150824Means for facilitating use, e.g. by people with impaired vision; means for indicating when used correctly or incorrectly; means for alarming by visual feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150977Arrays of piercing elements for simultaneous piercing
    • A61B5/150984Microneedles or microblades
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101Details
    • A61B5/15103Piercing procedure
    • A61B5/15107Piercing being assisted by a triggering mechanism
    • A61B5/15113Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101Details
    • A61B5/15115Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids
    • A61B5/15117Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15142Devices intended for single use, i.e. disposable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15186Devices loaded with a single lancet, i.e. a single lancet with or without a casing is loaded into a reusable drive device and then discarded after use; drive devices reloadable for multiple use
    • A61B5/15188Constructional features of reusable driving devices
    • A61B5/1519Constructional features of reusable driving devices comprising driving means, e.g. a spring, for propelling the piercing unit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743Type of operation; Specification of treatment sites
    • A61B2017/00747Dermatology
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046Solid microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Manufacturing & Machinery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Surgical Instruments (AREA)
  • Perforating, Stamping-Out Or Severing By Means Other Than Cutting (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Massaging Devices (AREA)
  • Medicinal Preparation (AREA)
MA27151A 2000-10-13 2003-05-12 Appareil et procédé de perçage de peau par microdents MA26057A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24030700P 2000-10-13 2000-10-13

Publications (1)

Publication Number Publication Date
MA26057A1 true MA26057A1 (fr) 2004-04-01

Family

ID=22906027

Family Applications (1)

Application Number Title Priority Date Filing Date
MA27151A MA26057A1 (fr) 2000-10-13 2003-05-12 Appareil et procédé de perçage de peau par microdents

Country Status (22)

Country Link
US (2) US7131960B2 (fr)
EP (1) EP1341453B1 (fr)
JP (1) JP4659332B2 (fr)
KR (1) KR20030068136A (fr)
CN (1) CN1250171C (fr)
AT (1) ATE428357T1 (fr)
AU (2) AU9682801A (fr)
BR (1) BR0114629A (fr)
CA (1) CA2425315C (fr)
CZ (1) CZ20031037A3 (fr)
DE (1) DE60138411D1 (fr)
ES (1) ES2324461T3 (fr)
HU (1) HUP0303558A2 (fr)
IL (1) IL155374A0 (fr)
MA (1) MA26057A1 (fr)
MX (1) MXPA03003299A (fr)
NO (1) NO20031681L (fr)
NZ (1) NZ525294A (fr)
PL (1) PL360998A1 (fr)
RU (1) RU2275871C2 (fr)
WO (1) WO2002030301A1 (fr)
ZA (1) ZA200303633B (fr)

Families Citing this family (138)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997048440A1 (fr) * 1996-06-18 1997-12-24 Alza Corporation Dispositif d'amelioration d'apport ou d'echantillonnage d'agents transdermiques
US6918901B1 (en) * 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
ES2324461T3 (es) * 2000-10-13 2009-08-07 Alza Corporation Aparato y procedimiento para perforar la piel con microprotuberancias.
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
JP4104975B2 (ja) * 2000-10-13 2008-06-18 アルザ・コーポレーシヨン 衝撃適用装置用の微小突起部材保持器
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
RU2282468C2 (ru) * 2000-10-26 2006-08-27 Алза Корпорейшн Устройство для трансдермальной доставки лекарственных средств, имеющее микровыступы с покрытием
WO2002074173A1 (fr) * 2001-03-16 2002-09-26 Alza Corporation Procede et appareil de revetement de microprojections de perçage de peau
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
MXPA03009603A (es) * 2001-04-20 2004-12-06 Johnson & Johnson Arreglo de microproyeccion que tiene un agente benefico que contiene un recubrimiento.
US20030199810A1 (en) * 2001-11-30 2003-10-23 Trautman Joseph Creagan Methods and apparatuses for forming microprojection arrays
AU2002357372B2 (en) * 2001-12-20 2008-11-20 Alza Corporation Skin-piercing microprojections having piercing depth control
US6912417B1 (en) 2002-04-05 2005-06-28 Ichor Medical Systmes, Inc. Method and apparatus for delivery of therapeutic agents
MXPA05000205A (es) * 2002-06-28 2005-09-30 Johnson & Johnson Dispositivos transdermicos para suministro de farmaco que tienen microprotrusiones revestidas.
KR101323980B1 (ko) * 2002-07-19 2013-10-30 쓰리엠 이노베이티브 프로퍼티즈 컴파니 마이크로 니들 장치, 마이크로 니들 장치를 사용하는 방법 및 마이크로 니들 장치를 송출하는 방법
US20040115167A1 (en) * 2002-09-30 2004-06-17 Michel Cormier Drug delivery device and method having coated microprojections incorporating vasoconstrictors
WO2004044557A2 (fr) 2002-11-12 2004-05-27 Argose, Inc. Mesure non invasive d'analytes
US20040106163A1 (en) * 2002-11-12 2004-06-03 Workman Jerome James Non-invasive measurement of analytes
AR042815A1 (es) * 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
US7087063B2 (en) * 2003-02-19 2006-08-08 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Abrasion device and method
US7226457B2 (en) * 2003-02-19 2007-06-05 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Epidermal sampling apparatus and method
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
ES2437565T3 (es) * 2003-06-30 2014-01-13 Alza Corporation Formulaciones para microproyecciones revestidas que contienen contraiones no volátiles
UY28398A1 (es) * 2003-07-02 2004-11-08 Alza Corp Método y parche de inmunización por disposición de microproyección
US20050031676A1 (en) * 2003-08-04 2005-02-10 Wong Patrick S.L. Method and device for enhancing transdermal agent flux
KR20060097751A (ko) * 2003-10-24 2006-09-15 알자 코포레이션 경피 약물 전달을 증대시키기 위한 장치 및 방법
JP2007510445A (ja) 2003-10-24 2007-04-26 アルザ・コーポレーシヨン 経皮薬剤送達促進用の前処置法及びシステム
CN1897882A (zh) * 2003-10-28 2007-01-17 阿尔扎公司 降低烟草使用频率的方法和装置
KR20070001886A (ko) * 2003-10-28 2007-01-04 알자 코포레이션 치료용 펩타이드 및 단백질의 폴리머 컨쥬게이트의 피복된미세돌출부를 통한 전달
WO2005044333A2 (fr) 2003-10-31 2005-05-19 Alza Corporation Applicateur a actionnement automatique pour reseau de micro-protuberances
WO2005065241A2 (fr) * 2003-12-24 2005-07-21 Argose, Inc. Rapporteurs de metabolites a petites molecules destines a etre utilises comme biocapteurs de glucose in vivo
EP1706171A1 (fr) * 2003-12-29 2006-10-04 3M Innovative Properties Company Dispositifs medicaux et kits comprenant ces dispositifs
CN1636505B (zh) * 2004-01-09 2011-11-09 希森美康株式会社 提取器具、提取装置和血糖值测量装置
CN102886101B (zh) 2004-03-08 2015-10-28 艾科医疗系统公司 改进的治疗剂电介导输送设备
EP1737357B1 (fr) 2004-03-24 2019-12-11 Corium, Inc. Dispositif d'administration transdermique
CA2562642A1 (fr) * 2004-04-13 2005-11-03 Alza Corporation Appareil et procede d'administration transdermique de multiples vaccins
AU2005244734A1 (en) 2004-05-13 2005-12-01 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents
US20060030811A1 (en) * 2004-08-03 2006-02-09 Wong Patrick S Method and device for enhancing transdermal agent flux
JP2008512199A (ja) * 2004-09-08 2008-04-24 アルザ コーポレイション 皮膚への接着及び伸展性(compliance)が改善された微小突起アレイ
US8267889B2 (en) 2004-11-18 2012-09-18 3M Innovative Properties Company Low-profile microneedle array applicator
CA2587386C (fr) 2004-11-18 2013-01-15 3M Innovative Properties Company Attache et applicateur pour jeu de micro-aiguilles
WO2006089056A2 (fr) * 2005-02-16 2006-08-24 Alza Corporation Dispositif et procede d'administration transdermique d'agents a base d'epoetine s
EP1869414A4 (fr) 2005-03-29 2010-07-28 Arkal Medical Inc Dispositifs, systemes, procedes et outils pour la surveillance continue du glucose
US10035008B2 (en) 2005-04-07 2018-07-31 3M Innovative Properties Company System and method for tool feedback sensing
US20060280644A1 (en) * 2005-06-02 2006-12-14 Scott Sellers Method for terminal sterilization of transdermal delivery devices
WO2007002523A2 (fr) * 2005-06-24 2007-01-04 3M Innovative Properties Company Timbre repliable et son procede d'application
JP5144510B2 (ja) 2005-06-27 2013-02-13 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイ適用装置
US20070078414A1 (en) * 2005-08-05 2007-04-05 Mcallister Devin V Methods and devices for delivering agents across biological barriers
CN101267896A (zh) * 2005-09-12 2008-09-17 阿尔扎公司 可涂覆的透皮给药微突起组合件
WO2007064486A1 (fr) * 2005-11-30 2007-06-07 3M Innovative Properties Company Reseaux de microaiguilles et leurs methodes d'utilisation
JP4963849B2 (ja) 2006-03-13 2012-06-27 シスメックス株式会社 微細孔形成システム
CN101466393A (zh) * 2006-03-15 2009-06-24 阿尔扎公司 用于经皮递送甲状旁腺激素药剂以治疗骨质减少的方法
US9119945B2 (en) * 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
WO2007127811A2 (fr) * 2006-04-25 2007-11-08 Alza Corporation Application d'un réseau de microsaillies, les microsaillies étant groupées pour accroître la charge médicamenteuse
WO2007127815A2 (fr) * 2006-04-25 2007-11-08 Alza Corporation Application d'un réseau de microprotubérances muni d'éléments de microprotubérances multicouches pour charge de médicament élevée
US20080058726A1 (en) * 2006-08-30 2008-03-06 Arvind Jina Methods and Apparatus Incorporating a Surface Penetration Device
AU2008209537B2 (en) 2007-01-22 2013-01-31 Corium Pharma Solutions, Inc. Applicators for microneedle arrays
CA2686093C (fr) 2007-04-16 2018-05-08 Corium International, Inc. Reseaux de micro-aiguilles coulees dans un solvant contenant un actif
WO2009048607A1 (fr) 2007-10-10 2009-04-16 Corium International, Inc. Distribution de vaccin par l'intermédiaire de réseaux de micro-aiguilles
US20090247984A1 (en) * 2007-10-24 2009-10-01 Masimo Laboratories, Inc. Use of microneedles for small molecule metabolite reporter delivery
US20100293807A1 (en) * 2007-10-29 2010-11-25 Transpharma Medical, Ltd. Vertical patch drying
US20090264911A1 (en) * 2008-04-16 2009-10-22 Kim Stanley I Single-use disposable lancing apparatus and methods
CN105999538A (zh) * 2008-11-18 2016-10-12 3M创新有限公司 空心微针阵列和方法
WO2010101620A2 (fr) 2009-03-02 2010-09-10 Seventh Sense Biosystems, Inc. Systèmes et procédés permettant de créer et d'utiliser des bulles de succion ou d'autres régions groupées de fluide dans la peau
US9295417B2 (en) 2011-04-29 2016-03-29 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
EP3354312A1 (fr) 2009-07-31 2018-08-01 3M Innovative Properties Co. Ensemble de micro-aiguilles creuses
US8409147B2 (en) * 2009-08-22 2013-04-02 Joseph Wayne Kraft Rapid local anesthesia linear injection device
US8088108B2 (en) * 2009-08-22 2012-01-03 Joseph Wayne Kraft Rapid local anesthesia injection cone
WO2011105496A1 (fr) * 2010-02-24 2011-09-01 久光製薬株式会社 Dispositif à micro-aiguilles
AU2011246880B2 (en) * 2010-04-28 2015-10-29 Sorrento Therapeutics, Inc. Medical devices for delivery of siRNA
DK2563450T3 (da) * 2010-04-28 2017-11-13 Kimberly Clark Co Apparat til administration af rheumatoid-arthritis-medikament
GB201007207D0 (en) 2010-04-29 2010-06-16 Univ Cork Method
CN102971038B (zh) 2010-05-04 2016-02-03 考里安国际公司 微针施加器
CA2798145C (fr) 2010-05-04 2022-10-18 Corium International, Inc. Methode et dispositif permettant l'administration transdermique d'hormone parathyroidienne au moyen d'un reseau de microprojections
WO2011148995A1 (fr) 2010-05-28 2011-12-01 久光製薬株式会社 Réseau à fines protubérances
US20130072874A1 (en) 2010-05-28 2013-03-21 Hisamitsu Pharmaceutical Co., Inc. Device having array provided with fine protrusions
JP5562138B2 (ja) 2010-06-24 2014-07-30 シスメックス株式会社 微細孔形成装置
EP2399635A1 (fr) 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto-injecteur
US20130158482A1 (en) 2010-07-26 2013-06-20 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
US8257379B2 (en) * 2010-07-29 2012-09-04 Kyphon Sarl Tissue structure perforation system and method
US20120039809A1 (en) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
EP2626107B1 (fr) * 2010-10-07 2021-05-26 Hisamitsu Pharmaceutical Co., Inc. Applicateur
DE202010013095U1 (de) 2010-12-10 2011-02-17 Mt Derm Gmbh Vorrichtung zum wiederholten Aufstechen von Haut und Stechmodul
EP2489380A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Dispositif d'injection
EP2489386A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489385A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
BR112013020874A2 (pt) 2011-02-18 2019-05-21 Endo Pharmaceuticals Inc. composto, regime, método para a preparação do referido composto, e, uso de um composto
EP2489384A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489382A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489390A1 (fr) * 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Mécanisme d'encliquetage
EP2489389A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Mécanisme d'encliquetage
EP2489388A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489381A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489387A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
KR20120119250A (ko) * 2011-04-21 2012-10-31 (주)마이티시스템 단턱이 형성된 미세바늘
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
WO2012149143A1 (fr) * 2011-04-29 2012-11-01 Seventh Sense Biosystems, Inc. Acheminement et/ou réception de fluides
EP3236259A1 (fr) 2011-04-29 2017-10-25 Seventh Sense Biosystems, Inc. Production de plasma ou de sérum et élimination de fluides sous pression réduite
JP6265740B2 (ja) * 2011-10-06 2018-01-24 久光製薬株式会社 アプリケータ
US10010707B2 (en) 2011-10-12 2018-07-03 3M Innovative Properties Company Integrated microneedle array delivery system
JP6495654B2 (ja) 2011-10-24 2019-04-03 アサナ バイオサイエンシズ,リミティド ライアビリティ カンパニー シクロヘキシルアミン類
USD733290S1 (en) 2012-01-27 2015-06-30 3M Innovative Properties Company Microneedle applicator
CN104245041B (zh) 2012-04-05 2016-08-17 久光制药株式会社 穿刺装置及其制造方法
EP2841147A4 (fr) * 2012-05-01 2016-04-13 Univ Pittsburgh Réseaux de micro-aiguilles à extrémité chargée pour l'insertion transdermique
JP6009302B2 (ja) * 2012-09-27 2016-10-19 シスメックス株式会社 微細孔形成装置、微細針チップおよびチップホルダ
WO2014053081A1 (fr) 2012-10-01 2014-04-10 The Hong Kong University Of Science And Technology Conception et fabrication de timbre transdermique non électronique à perfusion active et dispositif pour l'administration transdermique à travers la peau
EP2937111B1 (fr) 2012-12-21 2020-03-18 Hisamitsu Pharmaceutical Co., Inc. Applicateur
US11052231B2 (en) 2012-12-21 2021-07-06 Corium, Inc. Microarray for delivery of therapeutic agent and methods of use
KR102244475B1 (ko) * 2013-01-08 2021-04-23 쓰리엠 이노베이티브 프로퍼티즈 컴파니 마이크로니들 장치를 피부에 적용하기 위한 어플리케이터
BR112015022253B1 (pt) * 2013-03-12 2022-03-15 Corium, Inc Aplicador de microprojeções
CA2903459C (fr) 2013-03-15 2024-02-20 Corium International, Inc. Applicateurs de microprojection d'impacts multiples et procedes d'utilisation
KR102341601B1 (ko) 2013-03-15 2021-12-21 코리움, 인크. 치료제를 전달하기 위한 마이크로어레이 및 사용 방법
JP2016514133A (ja) 2013-03-15 2016-05-19 コリウム インターナショナル, インコーポレイテッド ポリマーを含まない微細構造物を含むマイクロアレイ、製造方法および使用方法
JP2016512754A (ja) 2013-03-15 2016-05-09 コリウム インターナショナル, インコーポレイテッド 治療剤の送達のためのマイクロアレイ、使用方法および製造方法
US20150038897A1 (en) 2013-07-30 2015-02-05 Zosano Pharma, Inc. Low-Profile Microneedle Patch Applicator
WO2015040697A1 (fr) 2013-09-18 2015-03-26 コスメディ製薬株式会社 Dispositif d'application de timbre de micro-aiguille et organe de retenue de timbre
JP6215343B2 (ja) 2013-11-05 2017-10-18 久光製薬株式会社 アプリケータ
AU2014365823B2 (en) 2013-12-16 2019-05-02 Abs Development 1, Inc. P2X3 and/or P2X2/3 compounds and methods
CN103654969B (zh) * 2013-12-24 2015-12-30 湖州美奇医疗器械有限公司 一种医疗助针器
WO2016036866A1 (fr) 2014-09-04 2016-03-10 Corium International, Inc. Matrice de microstructures, procédé de production et procédés d'utilisation
US10137289B2 (en) * 2014-12-20 2018-11-27 Esthetic Education LLC Microneedle cartridge and nosecone assembly
WO2016149673A1 (fr) 2015-03-18 2016-09-22 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Composés bioactifs conjugués à des substrats de réseaux de micro-aiguilles
MA41818A (fr) 2015-03-27 2018-01-30 Leo Pharma As Timbre à micro-aiguilles pour administration d'un principe actif à la peau
WO2017004067A1 (fr) 2015-06-29 2017-01-05 Corium International, Inc. Micro-réseau pour l'administration d'un agent thérapeutique, procédés d'utilisation, et procédés de fabrication
JP2017023404A (ja) * 2015-07-22 2017-02-02 日本写真印刷株式会社 マイクロニードルパッチ用インパクト付加型アプリケータ及び先端部材
EP3345648A4 (fr) 2015-09-02 2019-04-17 Hisamitsu Pharmaceutical Co., Inc. Applicateur
WO2017143345A1 (fr) 2016-02-19 2017-08-24 Zp Opco, Inc. Procédé pour obtenir rapidement des concentrations thérapeutiques de triptans pour le traitement de migraines
WO2017159779A1 (fr) 2016-03-16 2017-09-21 コスメディ製薬株式会社 Boîtier de timbre à micro-aiguilles
MX2018011742A (es) 2016-03-28 2019-02-14 Ichor Medical Systems Inc Metodo y aparato para suministro de agentes terapeuticos.
WO2018064135A1 (fr) 2016-09-30 2018-04-05 Asana Biosciences, Llc Composés p2x3 et/ou p2x2/3 et méthodes associées
JP6931217B2 (ja) 2017-03-28 2021-09-01 コスメディ製薬株式会社 水溶性シート状製剤のアプリケータ
EP3672570A1 (fr) 2017-08-23 2020-07-01 Zosano Pharma Corporation Procédé d'obtention rapide de concentrations thérapeutiques de zolmitriptan pour le traitement de migraines et de céphalées de horton
US11660264B2 (en) * 2017-08-23 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
WO2019077519A1 (fr) 2017-10-17 2019-04-25 3M Innovative Properties Company Applicateur pour appliquer une puce à injections à la peau
WO2019146618A1 (fr) 2018-01-24 2019-08-01 コスメディ製薬株式会社 Dispositif de liaison étanche pour micro-aiguille
US11660265B2 (en) 2018-06-28 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
DE102019200563A1 (de) * 2019-01-17 2020-07-23 Lts Lohmann Therapie-Systeme Ag Applikator
JP7491551B2 (ja) 2019-04-25 2024-05-28 コスメディ製薬株式会社 水溶性シート状製剤のアプリケータ2

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE25637E (en) * 1964-09-08 Means for vaccinating
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) * 1972-02-14 1973-08-13 Ici Ltd Pansements
EP0429842B1 (fr) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Dispositif d'administration transcutanée de médicaments à base de protéine ou de peptide
US5279544A (en) * 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
US6048337A (en) * 1992-01-07 2000-04-11 Principal Ab Transdermal perfusion of fluids
CN1098712C (zh) 1994-08-18 2003-01-15 Nmt集团公开有限公司 针缩回机构
JPH10510175A (ja) * 1994-12-09 1998-10-06 ノバルティス アクチェンゲゼルシャフト 経皮システム
AU5869796A (en) 1995-05-22 1996-12-11 Ned A. Godshall Micromechanical patch for enhancing the delivery of compound s through the skin
WO1996037155A1 (fr) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Dispositif micromecanique et procede pour ameliorer l'administration percutanee de composes
DE19525607A1 (de) 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
US5613978A (en) 1996-06-04 1997-03-25 Palco Laboratories Adjustable tip for lancet device
WO1997048440A1 (fr) 1996-06-18 1997-12-24 Alza Corporation Dispositif d'amelioration d'apport ou d'echantillonnage d'agents transdermiques
ATE241405T1 (de) 1996-07-03 2003-06-15 Altea Therapeutics Corp Mehrfache mechanische mikroperforierung von haut oder schleimhäuten
US5983136A (en) 1996-09-17 1999-11-09 Deka Products Limited Partnership System for delivery of drugs by transport
ES2195190T3 (es) * 1996-12-20 2003-12-01 Alza Corp Dispositivo y metodo para mejorar el flujo de agente transdermico.
DE19654391A1 (de) 1996-12-27 1998-07-02 Basf Ag Katalysator zur selektiven Herstellung von Propylen aus Propan
US6918901B1 (en) * 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
KR100557261B1 (ko) * 1997-12-11 2006-03-07 알자 코포레이션 경피성 작용제 유동률을 증진시키기 위한 장치
KR100572539B1 (ko) 1997-12-11 2006-04-24 알자 코포레이션 경피성 작용제 유동률을 증진시키기 위한 장치
KR100561892B1 (ko) * 1997-12-11 2006-03-16 알자 코포레이션 경피성 작용제 유동률을 증진시키기 위한 장치
AU767122B2 (en) 1998-06-10 2003-10-30 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
GB9817662D0 (en) * 1998-08-13 1998-10-07 Crocker Peter J Substance delivery
PT1189660E (pt) * 1999-06-08 2006-09-29 Altea Therapeutics Corp Equipamento para a formacao de microporos em membranas biologicas utilizando dispositivos de interface para o tecido de pelicula fina e processo para o mesmo
US6364889B1 (en) * 1999-11-17 2002-04-02 Bayer Corporation Electronic lancing device
WO2001043643A1 (fr) * 1999-12-16 2001-06-21 Alza Corporation Dispositif destine a augmenter le flux transdermique de substances echantillonnees
ES2324461T3 (es) * 2000-10-13 2009-08-07 Alza Corporation Aparato y procedimiento para perforar la piel con microprotuberancias.
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
JP4104975B2 (ja) * 2000-10-13 2008-06-18 アルザ・コーポレーシヨン 衝撃適用装置用の微小突起部材保持器
ES2243564T3 (es) * 2000-10-13 2005-12-01 Alza Corporation Aplicador de red de microlamas que produce un impacto.
US7108681B2 (en) * 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
RU2282468C2 (ru) * 2000-10-26 2006-08-27 Алза Корпорейшн Устройство для трансдермальной доставки лекарственных средств, имеющее микровыступы с покрытием
WO2002074173A1 (fr) * 2001-03-16 2002-09-26 Alza Corporation Procede et appareil de revetement de microprojections de perçage de peau
MXPA03009603A (es) * 2001-04-20 2004-12-06 Johnson & Johnson Arreglo de microproyeccion que tiene un agente benefico que contiene un recubrimiento.
US6591124B2 (en) * 2001-05-11 2003-07-08 The Procter & Gamble Company Portable interstitial fluid monitoring system
US6767341B2 (en) * 2001-06-13 2004-07-27 Abbott Laboratories Microneedles for minimally invasive drug delivery
US20030199810A1 (en) * 2001-11-30 2003-10-23 Trautman Joseph Creagan Methods and apparatuses for forming microprojection arrays
AU2002357372B2 (en) * 2001-12-20 2008-11-20 Alza Corporation Skin-piercing microprojections having piercing depth control
MXPA05000205A (es) * 2002-06-28 2005-09-30 Johnson & Johnson Dispositivos transdermicos para suministro de farmaco que tienen microprotrusiones revestidas.
AR042815A1 (es) * 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
ES2437565T3 (es) * 2003-06-30 2014-01-13 Alza Corporation Formulaciones para microproyecciones revestidas que contienen contraiones no volátiles
KR20070001886A (ko) * 2003-10-28 2007-01-04 알자 코포레이션 치료용 펩타이드 및 단백질의 폴리머 컨쥬게이트의 피복된미세돌출부를 통한 전달
WO2005044333A2 (fr) * 2003-10-31 2005-05-19 Alza Corporation Applicateur a actionnement automatique pour reseau de micro-protuberances
WO2005051456A2 (fr) * 2003-11-13 2005-06-09 Alza Corporation Composition et appareil d'administration transdermique
AU2005244734A1 (en) * 2004-05-13 2005-12-01 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents

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CA2425315A1 (fr) 2002-04-18
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US7798987B2 (en) 2010-09-21
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