LV10458B - 4,13-dioxabicyclo£8.2.1.|tridecenone derivatives, method and intermediate products for preparation thereof and drugs containing that compounds - Google Patents

4,13-dioxabicyclo£8.2.1.|tridecenone derivatives, method and intermediate products for preparation thereof and drugs containing that compounds Download PDF

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Publication number
LV10458B
LV10458B LVP-93-01A LV930001A LV10458B LV 10458 B LV10458 B LV 10458B LV 930001 A LV930001 A LV 930001A LV 10458 B LV10458 B LV 10458B
Authority
LV
Latvia
Prior art keywords
formula
der
methyl
dioxabicyclo
die
Prior art date
Application number
LVP-93-01A
Other languages
English (en)
Latvian (lv)
Other versions
LV10458A (lv
Inventor
Hiltje Dagmar
Preuschoff Ulf
Eeckhout Christian
Original Assignee
Kali Chemie Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Pharma Gmbh filed Critical Kali Chemie Pharma Gmbh
Publication of LV10458A publication Critical patent/LV10458A/xx
Publication of LV10458B publication Critical patent/LV10458B/lv

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
LVP-93-01A 1992-01-07 1993-01-06 4,13-dioxabicyclo£8.2.1.|tridecenone derivatives, method and intermediate products for preparation thereof and drugs containing that compounds LV10458B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4200145A DE4200145A1 (de) 1992-01-07 1992-01-07 7,10-epoxy-oxacyclododecan-derivate, verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
LV10458A LV10458A (lv) 1995-02-20
LV10458B true LV10458B (en) 1996-02-20

Family

ID=6449136

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-93-01A LV10458B (en) 1992-01-07 1993-01-06 4,13-dioxabicyclo£8.2.1.|tridecenone derivatives, method and intermediate products for preparation thereof and drugs containing that compounds

Country Status (28)

Country Link
US (1) US5418224A (sk)
EP (1) EP0550895B1 (sk)
JP (1) JP3300084B2 (sk)
KR (1) KR100273937B1 (sk)
CN (1) CN1033646C (sk)
AT (1) ATE155478T1 (sk)
AU (1) AU667699B2 (sk)
CA (1) CA2086811C (sk)
CZ (1) CZ281773B6 (sk)
DE (2) DE4200145A1 (sk)
DK (1) DK0550895T3 (sk)
DZ (1) DZ1652A1 (sk)
ES (1) ES2104808T3 (sk)
FI (1) FI106862B (sk)
GR (1) GR3024859T3 (sk)
HK (1) HK1014003A1 (sk)
HU (2) HU212272B (sk)
IL (1) IL104158A (sk)
LT (1) LT3015B (sk)
LV (1) LV10458B (sk)
MX (1) MX9300045A (sk)
NO (1) NO179586C (sk)
PH (1) PH30098A (sk)
RU (1) RU2107070C1 (sk)
SK (1) SK279251B6 (sk)
TW (1) TW238308B (sk)
UA (1) UA29393C2 (sk)
ZA (1) ZA9339B (sk)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL123583A (en) * 1995-10-13 2003-07-31 Neurosearch As 3-substituted -8-azabicyclo [3,2,1] oct-2-ene derivatives, their preparation and pharmaceutical compositions containing them
US6077943A (en) * 1996-03-01 2000-06-20 Takeda Chemical Industries, Ltd. Method of producing erythromycin derivative
CA2247929A1 (en) * 1996-03-01 1997-09-04 Miichiro Arita Processes for the preparation of erythromycin derivatives
DE19644195A1 (de) * 1996-10-24 1998-04-30 Solvay Pharm Gmbh 10,13,15-Trioxatricyclo[9.2.1.1.·9·.·6·]-pentadecanon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US6165985A (en) * 1998-02-13 2000-12-26 Solvay Pharmaceuticals Gmbh 11-acetyl-12,13-dioxabicyclo[8.2.1]-tridecenone derivatives, processes for their preparation and pharmaceutical compositions comprising them
DE19805822B4 (de) * 1998-02-13 2009-02-05 Solvay Pharmaceuticals Gmbh 11-Acetyl-12,13-dioxabicyclo[8.2.1]tridecenon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
PT1489090E (pt) * 2000-08-17 2006-05-31 Kitasato Inst Novos derivados de pseudoeritromicina
JP2004529184A (ja) * 2001-05-10 2004-09-24 ゾルファイ　ファーマスーティカルズ　ゲゼルシャフト　ミット　ベシュレンクテル　ハフツング 新規１−アミドメチルカルボニル−ピペリジン誘導体、該誘導体を製造するための方法及び中間体並びにこれらの化合物を含有している医薬
US20040067896A1 (en) * 2002-07-25 2004-04-08 The Kitasato Institute Novel pseudoerythromycin derivatives
US7521420B2 (en) 2003-06-18 2009-04-21 Tranzyme Pharma, Inc. Macrocyclic antagonists of the motilin receptor
US7582611B2 (en) * 2005-05-24 2009-09-01 Pfizer Inc. Motilide compounds
CA2632779A1 (en) * 2005-12-08 2007-06-14 Pfizer Inc. Method for demethylating the 3'-dimethylamino group of erythromycin compounds
JP5684474B2 (ja) 2006-09-11 2015-03-11 オセラ セラピューティクス， インコーポレイテッド 胃腸の運動障害疾患の治療のためのモチリン受容体の大環状アンタゴニスト
EP2104680B1 (en) * 2006-12-05 2013-01-09 Bristol-Myers Squibb Company Motilide polymorphs
US20080287371A1 (en) * 2007-05-17 2008-11-20 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex
WO2014156339A1 (ja) * 2013-03-25 2014-10-02 ゼリア新薬工業株式会社 食後期の胃運動亢進剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3725385A (en) * 1970-11-02 1973-04-03 Abbott Lab Process for the demethylation of 3-amino macrolides
CA1321581C (en) * 1987-05-26 1993-08-24 Herbert A. Kirst Ring-contracted macrolides
US5106961A (en) * 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives
US4920102A (en) * 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders

Also Published As

Publication number Publication date
HU9204076D0 (en) 1993-04-28
NO179586C (no) 1996-11-06
RU2107070C1 (ru) 1998-03-20
LT3015B (lt) 1994-08-25
SK341492A3 (en) 1995-05-10
FI106862B (fi) 2001-04-30
DE4200145A1 (de) 1993-07-08
MX9300045A (es) 1993-12-01
ES2104808T3 (es) 1997-10-16
EP0550895B1 (de) 1997-07-16
HK1014003A1 (en) 1999-09-17
NO930029D0 (no) 1993-01-06
CN1033646C (zh) 1996-12-25
CZ341492A3 (en) 1993-07-14
CA2086811C (en) 2003-12-09
AU667699B2 (en) 1996-04-04
HU212272B (en) 1996-04-29
JPH07247299A (ja) 1995-09-26
IL104158A0 (en) 1993-05-13
LTIP187A (lt) 1994-03-25
DZ1652A1 (fr) 2002-02-17
JP3300084B2 (ja) 2002-07-08
US5418224A (en) 1995-05-23
NO179586B (no) 1996-07-29
FI930051A0 (fi) 1993-01-07
AU3103693A (en) 1993-07-08
GR3024859T3 (en) 1998-01-30
HU210216A9 (en) 1995-02-28
CZ281773B6 (cs) 1997-01-15
PH30098A (en) 1996-12-27
DE59208710D1 (de) 1997-08-21
NO930029L (no) 1993-07-08
SK279251B6 (sk) 1998-08-05
CN1075320A (zh) 1993-08-18
HUT66234A (en) 1994-10-28
CA2086811A1 (en) 1993-07-08
ZA9339B (en) 1993-08-05
ATE155478T1 (de) 1997-08-15
KR930016436A (ko) 1993-08-26
UA29393C2 (uk) 2000-11-15
IL104158A (en) 1997-07-13
TW238308B (sk) 1995-01-11
LV10458A (lv) 1995-02-20
EP0550895A1 (de) 1993-07-14
FI930051A (fi) 1993-07-08
DK0550895T3 (da) 1997-08-25
KR100273937B1 (ko) 2000-12-15

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