LU92710I2 - Ramucirumab et ses dérivés pharmaceutiquement acceptables (cyramza) - Google Patents

Ramucirumab et ses dérivés pharmaceutiquement acceptables (cyramza) Download PDF

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Publication number
LU92710I2
LU92710I2 LU92710C LU92710C LU92710I2 LU 92710 I2 LU92710 I2 LU 92710I2 LU 92710 C LU92710 C LU 92710C LU 92710 C LU92710 C LU 92710C LU 92710 I2 LU92710 I2 LU 92710I2
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LU
Luxembourg
Prior art keywords
antibodies
cyramza
ramucirumab
pharmaceutically acceptable
acceptable derivatives
Prior art date
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LU92710C
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English (en)
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Imclone Llc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27805075&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU92710(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Imclone Llc filed Critical Imclone Llc
Publication of LU92710I2 publication Critical patent/LU92710I2/fr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
LU92710C 2002-03-04 2015-05-06 Ramucirumab et ses dérivés pharmaceutiquement acceptables (cyramza) LU92710I2 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36178302P 2002-03-04 2002-03-04

Publications (1)

Publication Number Publication Date
LU92710I2 true LU92710I2 (fr) 2015-11-02

Family

ID=27805075

Family Applications (1)

Application Number Title Priority Date Filing Date
LU92710C LU92710I2 (fr) 2002-03-04 2015-05-06 Ramucirumab et ses dérivés pharmaceutiquement acceptables (cyramza)

Country Status (18)

Country Link
US (2) US7498414B2 (fr)
EP (3) EP1916001B1 (fr)
JP (3) JP2005526506A (fr)
AT (2) ATE510561T1 (fr)
AU (1) AU2003213687A1 (fr)
BE (1) BE2015C027I2 (fr)
CA (1) CA2478169C (fr)
CY (3) CY1111141T1 (fr)
DE (1) DE60333554D1 (fr)
DK (2) DK1487856T3 (fr)
ES (2) ES2347543T3 (fr)
FR (1) FR15C0034I2 (fr)
HK (1) HK1118229A1 (fr)
HU (1) HUS1500025I1 (fr)
LU (1) LU92710I2 (fr)
PT (2) PT1916001E (fr)
SI (2) SI1487856T1 (fr)
WO (1) WO2003075840A2 (fr)

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* Cited by examiner, † Cited by third party
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EP1916001B1 (fr) 2011-05-25
CA2478169A1 (fr) 2003-09-18
SI1487856T1 (sl) 2010-12-31
EP2298346A2 (fr) 2011-03-23
JP2012105667A (ja) 2012-06-07
JP5476404B2 (ja) 2014-04-23
WO2003075840A2 (fr) 2003-09-18
AU2003213687A8 (en) 2003-09-22
HUS1500025I1 (hu) 2017-04-28
US20090142358A1 (en) 2009-06-04
CY1111141T1 (el) 2015-06-11
EP1916001A3 (fr) 2008-08-13
CA2478169C (fr) 2013-04-16
AU2003213687A1 (en) 2003-09-22
JP2005526506A (ja) 2005-09-08
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US8057791B2 (en) 2011-11-15
CY2015018I1 (el) 2016-04-13
US7498414B2 (en) 2009-03-03
ATE475431T1 (de) 2010-08-15
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ES2362931T3 (es) 2011-07-15
EP1487856B1 (fr) 2010-07-28
ES2347543T3 (es) 2010-11-02
SI1916001T1 (sl) 2011-10-28
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