CY1113190T1 - Μεθοδος αγωγης της αιμολυτικης νοσου - Google Patents
Μεθοδος αγωγης της αιμολυτικης νοσουInfo
- Publication number
- CY1113190T1 CY1113190T1 CY20121100783T CY121100783T CY1113190T1 CY 1113190 T1 CY1113190 T1 CY 1113190T1 CY 20121100783 T CY20121100783 T CY 20121100783T CY 121100783 T CY121100783 T CY 121100783T CY 1113190 T1 CY1113190 T1 CY 1113190T1
- Authority
- CY
- Cyprus
- Prior art keywords
- treatment
- hemolytic disease
- hemolytic
- complement
- binds
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 230000002949 hemolytic effect Effects 0.000 title abstract 2
- 208000000733 Paroxysmal Hemoglobinuria Diseases 0.000 abstract 1
- 102100036050 Phosphatidylinositol N-acetylglucosaminyltransferase subunit A Human genes 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 201000003045 paroxysmal nocturnal hemoglobinuria Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
Abstract
Η παροξυσμική νυκτερινή αιμοσφαιρινουρία ή άλλες αιμολυτικές νόσοι υποβάλλονται σε αγωγή δια της χρήσεως μίας ενώσεως που δεσμεύεται σε ή κατά τα άλλα καταστέλλει τη δημιουργία και/ή τη δράση ενός ή περισσότερων συνιστωσών του συμπληρώματος, όπως, για παράδειγμα, ενός αντισώματος ανασταλτικού του συμπληρώματος.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/771,552 US20050169921A1 (en) | 2004-02-03 | 2004-02-03 | Method of treating hemolytic disease |
EP05712607A EP1720571B9 (en) | 2004-02-03 | 2005-02-03 | Method of treating hemolytic disease |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1113190T1 true CY1113190T1 (el) | 2016-04-13 |
Family
ID=34808492
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20121100783T CY1113190T1 (el) | 2004-02-03 | 2012-08-30 | Μεθοδος αγωγης της αιμολυτικης νοσου |
Country Status (17)
Country | Link |
---|---|
US (5) | US20050169921A1 (el) |
EP (7) | EP2522363A1 (el) |
JP (5) | JP2007520494A (el) |
KR (1) | KR101197799B1 (el) |
CN (4) | CN1938047A (el) |
AU (1) | AU2005209854B2 (el) |
CA (1) | CA2554632A1 (el) |
CY (1) | CY1113190T1 (el) |
DK (1) | DK1720571T3 (el) |
ES (1) | ES2389093T3 (el) |
HK (1) | HK1094950A1 (el) |
IL (2) | IL177003A0 (el) |
NZ (1) | NZ549328A (el) |
PL (1) | PL1720571T3 (el) |
PT (1) | PT1720571E (el) |
SI (1) | SI1720571T1 (el) |
WO (1) | WO2005074607A2 (el) |
Families Citing this family (53)
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US6969601B2 (en) | 1997-04-03 | 2005-11-29 | Jensenius Jens Chr | MASP-2, a complement-fixing enzyme, and uses for it |
NZ538384A (en) * | 2002-09-06 | 2009-04-30 | Alexion Pharma Inc | Treatment for asthma using a compound which binds to or otherwise blocks the generation and/or activity of one or more complement components reptors, such as, C5a receptors |
US9415102B2 (en) | 2002-09-06 | 2016-08-16 | Alexion Pharmaceuticals, Inc. | High concentration formulations of anti-C5 antibodies |
US20050271660A1 (en) * | 2002-09-06 | 2005-12-08 | Alexion Pharmaceuticals, Inc. | Nebulization of monoclonal antibodies for treating pulmonary diseases |
US20050169921A1 (en) * | 2004-02-03 | 2005-08-04 | Leonard Bell | Method of treating hemolytic disease |
US20070116710A1 (en) * | 2004-02-03 | 2007-05-24 | Leonard Bell | Methods of treating hemolytic anemia |
AU2005244012C1 (en) * | 2004-05-14 | 2013-05-02 | Alexion Pharmaceuticals, Inc. | Prolongation of survival of an allograft by inhibiting complement activity |
US7919094B2 (en) * | 2004-06-10 | 2011-04-05 | Omeros Corporation | Methods for treating conditions associated with MASP-2 dependent complement activation |
US8840893B2 (en) | 2004-06-10 | 2014-09-23 | Omeros Corporation | Methods for treating conditions associated with MASP-2 dependent complement activation |
WO2006107708A1 (en) * | 2005-04-04 | 2006-10-12 | Alexion Pharmaceuticals, Inc. | Treatment of disease caused by excess free hemoglobin |
WO2007056227A2 (en) * | 2005-11-04 | 2007-05-18 | Genentech, Inc. | Use of complement pathway inhibitors to treat ocular diseases |
SI1988882T1 (sl) * | 2006-03-02 | 2015-07-31 | Alexion Pharmaceuticals, Inc. | Podaljšanje preživetja alografta z inhibiranjem aktivnosti komplementa |
CA3022097C (en) * | 2006-03-15 | 2020-10-27 | Alexion Pharmaceuticals, Inc. | Treatment of paroxysmal nocturnal hemoglobinuria patients by an inhibitor of complement |
EP4001409A1 (en) | 2006-03-31 | 2022-05-25 | Chugai Seiyaku Kabushiki Kaisha | Methods for controlling blood pharmacokinetics of antibodies |
PL2698166T3 (pl) | 2006-10-10 | 2016-03-31 | Regenesance B V | Hamowanie układu dopełniacza służące do lepszej regeneracji nerwów |
PE20081259A1 (es) | 2006-11-02 | 2008-10-31 | Genentech Inc | Anticuerpos anti-factor d humanizados |
CN101874042B9 (zh) | 2007-09-26 | 2019-01-01 | 中外制药株式会社 | 利用cdr的氨基酸取代来改变抗体等电点的方法 |
NZ602884A (en) | 2008-04-11 | 2014-08-29 | Chugai Pharmaceutical Co Ltd | Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly |
CR20170001A (es) | 2008-04-28 | 2017-08-10 | Genentech Inc | Anticuerpos anti factor d humanizados |
MY159396A (en) * | 2008-08-05 | 2016-12-30 | Novartis Ag | Compositions and methods for antibodies targeting complement protein c5 |
HRP20230167T1 (hr) * | 2008-11-10 | 2023-03-31 | Alexion Pharmaceuticals, Inc. | Postupci i pripravci za liječenje poremećaja povezanih s komplementom |
CA2971474C (en) * | 2009-10-16 | 2022-11-22 | Omeros Corporation | Methods for treating disseminated intravascular coagulation by inhibiting masp-2 dependent complement activation |
US20110124019A1 (en) * | 2009-11-25 | 2011-05-26 | The Charlotte-Mecklenburg Hospital Authority | Method of using carbonic anhydrase to detect hemolysis |
US9420770B2 (en) | 2009-12-01 | 2016-08-23 | Indiana University Research & Technology Corporation | Methods of modulating thrombocytopenia and modified transgenic pigs |
JP5932670B2 (ja) * | 2010-03-11 | 2016-06-08 | ライナット ニューロサイエンス コーポレイション | pH依存性の抗原結合を有する抗体 |
KR102385507B1 (ko) | 2010-11-30 | 2022-04-12 | 추가이 세이야쿠 가부시키가이샤 | 복수 분자의 항원에 반복해서 결합하는 항원 결합 분자 |
AU2015230852B2 (en) * | 2011-03-08 | 2017-09-14 | Alexion Pharmaceuticals, Inc. | High concentration antibody formulations |
US9644035B2 (en) | 2011-04-08 | 2017-05-09 | Omeros Corporation | Methods for treating conditions associated with MASP-2 dependent complement activation |
ES2683307T3 (es) * | 2011-04-08 | 2018-09-26 | University Of Leicester | Métodos para tratar afecciones asociadas con la activación de complemento dependiente de MASP-2 |
EP2794656B1 (en) | 2011-12-21 | 2019-02-27 | Novartis AG | Compositions comprising antibodies targeting factor p and c5 |
WO2013137912A2 (en) * | 2012-03-16 | 2013-09-19 | Alexion Pharmaceuticals, Inc. | Methods of distributing complement-inhibiting drugs to patients receiving a complement inhibitor |
IN2014KN02324A (el) * | 2012-04-06 | 2015-05-01 | Omeros Corp | |
US9579360B2 (en) * | 2012-06-20 | 2017-02-28 | The Trustees Of The University Of Pennsylvania | Methods of treating or preventing periodontitis and diseases associated with periodontitis |
CA2897334A1 (en) * | 2013-03-29 | 2014-10-02 | Alexion Pharmaceuticals, Inc. | Compositions and methods for increasing the serum half-life of a therapeutic agent targeting complement c5 |
SI3011345T1 (sl) | 2013-08-07 | 2017-12-29 | Alexion Pharmaceuticals, Inc. | Biomarkerski proteini za atipični hemolitični uremični sindrom (ahus) |
EA201690213A1 (ru) | 2013-08-12 | 2016-07-29 | Дженентек, Инк. | Композиции и способ лечения связанных с комплементом состояний |
CN105683219B (zh) | 2013-10-17 | 2020-07-14 | 奥默罗斯公司 | 用于治疗与masp-2依赖性补体活化有关的病况的方法 |
MA39934A (fr) | 2014-05-01 | 2017-03-08 | Hoffmann La Roche | Variants d'anticorps anti-facteur d et leurs utilisations |
AU2015365167B2 (en) | 2014-12-19 | 2021-07-29 | Chugai Seiyaku Kabushiki Kaisha | Anti-C5 antibodies and methods of use |
JP2018511557A (ja) | 2015-01-22 | 2018-04-26 | 中外製薬株式会社 | 2種以上の抗c5抗体の組み合わせおよび使用方法 |
US20190135903A1 (en) * | 2015-03-31 | 2019-05-09 | Alexion Pharmaceuticals, Inc. | Identifying and treating subpopulations of paroxysmal nocturnal hemoglobinuria (pnh) patients |
US10654932B2 (en) | 2015-10-30 | 2020-05-19 | Genentech, Inc. | Anti-factor D antibody variant conjugates and uses thereof |
TW201730211A (zh) | 2015-10-30 | 2017-09-01 | 建南德克公司 | 抗因子d抗體及結合物 |
CA3027487A1 (en) | 2016-06-14 | 2017-12-21 | Regeneron Pharmaceuticals, Inc. | Anti-c5 antibodies and uses thereof |
SG11201801024XA (en) | 2016-08-05 | 2018-05-30 | Chugai Pharmaceutical Co Ltd | Therapeutic or preventive compositions for il-8-related diseases |
IT201600121482A1 (it) * | 2016-11-30 | 2018-05-30 | Univ Degli Studi Di Verona | Fattore H per l’uso nel trattamento e/o prevenzione della formazione di eterotrombi in pazienti affetti da anemia falciforme |
SG10201908697XA (en) | 2017-01-31 | 2019-10-30 | Chugai Pharmaceutical Co Ltd | A pharmaceutical composition for use in the treatment or prevention of a c5-related disease and a method for treating or preventing a c5-related disease |
AU2018383751A1 (en) | 2017-12-13 | 2020-06-25 | Regeneron Pharmaceuticals, Inc. | Anti-C5 antibody combinations and uses thereof |
GB201800620D0 (en) | 2018-01-15 | 2018-02-28 | Univ Manchester | C3b Binding Polypeptide |
CN112512656A (zh) | 2018-05-30 | 2021-03-16 | 加利福尼亚大学董事会 | 用于组织和细胞聚集体解离及单细胞富集的微流体过滤装置及方法 |
CN112512563A (zh) | 2018-08-01 | 2021-03-16 | 中外制药株式会社 | 用于治疗或预防c5相关疾病的药物组合物和治疗或预防c5相关疾病的方法 |
MX2022001154A (es) | 2019-07-31 | 2022-02-22 | Hoffmann La Roche | Regimen de dosificacion y administracion para el tratamiento o prevencion de enfermedades relacionadas con c5 mediante el uso del anticuerpo anti-c5 crovalimab. |
TW202120124A (zh) | 2019-07-31 | 2021-06-01 | 瑞士商赫孚孟拉羅股份公司 | 藉由使用抗c5抗體克羅伐單抗(crovalimab)之治療或預防c5相關疾病之劑量及投藥療程 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4686100A (en) * | 1985-04-02 | 1987-08-11 | The Board Of Trustees Of The Leland Stanford Junior University | Method for the treatment of adult respiratory distress syndrome |
US5135916A (en) * | 1989-06-12 | 1992-08-04 | Oklahoma Medical Research Foundation | Inhibition of complement mediated inflammatory response |
DE3924924A1 (de) | 1989-07-27 | 1991-02-07 | Goetze Otto | Verfahren zum nachweis und/oder der quantitativen bestimmung von komplementpeptid c5a und/oder c5adesarg |
US6074642A (en) * | 1994-05-02 | 2000-06-13 | Alexion Pharmaceuticals, Inc. | Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis |
US5650825A (en) * | 1995-03-31 | 1997-07-22 | Matsushita Electric Corporation Of America | Method and apparatus for sending private data instead of stuffing bits in an MPEG bit stream |
DE19826743A1 (de) * | 1998-06-16 | 1999-12-23 | Bayer Ag | Verfahren zur Herstellung von geträgerten Polymerisationskatalysatorsystemen und Verwendung dieser zur Homo- und Copolymerisation ungesättigter Monomere |
CA2436671C (en) * | 2000-12-05 | 2015-02-03 | Alexion Pharmaceuticals, Inc. | Rationally designed antibodies |
AU2003223288A1 (en) * | 2002-03-18 | 2003-10-08 | Alexion Pharmaceuticals, Inc. | Stratification of patient populations having or suspected of having rheumatoid arthritis |
US7361339B2 (en) * | 2003-01-09 | 2008-04-22 | Alexion Pharmaceuticals, Inc. | Methods for reducing morality associated with acute myocardial infarction |
US20050169921A1 (en) * | 2004-02-03 | 2005-08-04 | Leonard Bell | Method of treating hemolytic disease |
-
2004
- 2004-02-03 US US10/771,552 patent/US20050169921A1/en not_active Abandoned
-
2005
- 2005-02-03 SI SI200531579T patent/SI1720571T1/sl unknown
- 2005-02-03 PT PT05712607T patent/PT1720571E/pt unknown
- 2005-02-03 EP EP12169519A patent/EP2522363A1/en not_active Withdrawn
- 2005-02-03 CN CNA2005800106310A patent/CN1938047A/zh active Pending
- 2005-02-03 ES ES05712607T patent/ES2389093T3/es active Active
- 2005-02-03 CN CN201410147935.2A patent/CN103977403A/zh active Pending
- 2005-02-03 KR KR1020067017880A patent/KR101197799B1/ko active IP Right Review Request
- 2005-02-03 CN CN2013103817575A patent/CN103446584A/zh active Pending
- 2005-02-03 CN CN201410147793.XA patent/CN103977402A/zh active Pending
- 2005-02-03 EP EP05712607A patent/EP1720571B9/en not_active Revoked
- 2005-02-03 PL PL05712607T patent/PL1720571T3/pl unknown
- 2005-02-03 EP EP12169343A patent/EP2522361A1/en not_active Withdrawn
- 2005-02-03 EP EP12169526A patent/EP2522364A1/en not_active Withdrawn
- 2005-02-03 US US11/050,543 patent/US20050191298A1/en not_active Abandoned
- 2005-02-03 WO PCT/US2005/003225 patent/WO2005074607A2/en active Application Filing
- 2005-02-03 AU AU2005209854A patent/AU2005209854B2/en active Active
- 2005-02-03 CA CA002554632A patent/CA2554632A1/en not_active Abandoned
- 2005-02-03 NZ NZ549328A patent/NZ549328A/en not_active IP Right Cessation
- 2005-02-03 EP EP12169508A patent/EP2520311A3/en not_active Withdrawn
- 2005-02-03 EP EP15150658.1A patent/EP2910253A1/en not_active Withdrawn
- 2005-02-03 EP EP12169513A patent/EP2522362A1/en not_active Withdrawn
- 2005-02-03 DK DK05712607.0T patent/DK1720571T3/da active
- 2005-02-03 JP JP2006551599A patent/JP2007520494A/ja not_active Withdrawn
-
2006
- 2006-07-20 IL IL177003A patent/IL177003A0/en unknown
-
2007
- 2007-03-06 HK HK07102472.6A patent/HK1094950A1/xx not_active IP Right Cessation
-
2009
- 2009-11-19 US US12/621,792 patent/US20100068202A1/en not_active Abandoned
-
2010
- 2010-10-12 US US12/902,617 patent/US20110086040A1/en not_active Abandoned
-
2011
- 2011-03-23 JP JP2011065075A patent/JP2011126917A/ja not_active Withdrawn
- 2011-12-22 US US13/335,518 patent/US20120308559A1/en not_active Abandoned
-
2012
- 2012-08-30 CY CY20121100783T patent/CY1113190T1/el unknown
-
2013
- 2013-07-11 JP JP2013145341A patent/JP5873047B2/ja active Active
-
2015
- 2015-01-29 JP JP2015015028A patent/JP2015083611A/ja not_active Withdrawn
- 2015-08-06 IL IL240410A patent/IL240410A0/en unknown
-
2017
- 2017-01-06 JP JP2017000897A patent/JP2017057234A/ja active Pending
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