LU88266I2 - - Google Patents

Info

Publication number
LU88266I2
LU88266I2 LU88266C LU88266C LU88266I2 LU 88266 I2 LU88266 I2 LU 88266I2 LU 88266 C LU88266 C LU 88266C LU 88266 C LU88266 C LU 88266C LU 88266 I2 LU88266 I2 LU 88266I2
Authority
LU
Luxembourg
Application number
LU88266C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10564759&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU88266(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of LU88266I2 publication Critical patent/LU88266I2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • C07D203/14—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom with carbocyclic rings directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
LU88266C 1984-08-01 1985-08-01 LU88266I2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848419575A GB8419575D0 (en) 1984-08-01 1984-08-01 Chemical compounds

Publications (1)

Publication Number Publication Date
LU88266I2 true LU88266I2 (ru) 1994-02-03

Family

ID=10564759

Family Applications (2)

Application Number Title Priority Date Filing Date
LU88266C LU88266I2 (ru) 1984-08-01 1985-08-01
LU86032A LU86032A1 (fr) 1984-08-01 1985-08-01 Derive d'indole

Family Applications After (1)

Application Number Title Priority Date Filing Date
LU86032A LU86032A1 (fr) 1984-08-01 1985-08-01 Derive d'indole

Country Status (42)

Country Link
US (1) US5037845A (ru)
JP (1) JPH0623197B2 (ru)
KR (1) KR930003759B1 (ru)
AT (1) AT386196B (ru)
AU (1) AU573878B2 (ru)
BE (1) BE903006A (ru)
CA (1) CA1241004A (ru)
CH (1) CH666026A5 (ru)
CZ (1) CZ280530B6 (ru)
DE (1) DE3527648A1 (ru)
DK (1) DK158942C (ru)
DO (1) DOP1989004759A (ru)
EC (1) ECSP941096A (ru)
EG (1) EG17283A (ru)
ES (6) ES8700234A1 (ru)
FI (1) FI78466C (ru)
FR (1) FR2568571B1 (ru)
GB (1) GB8419575D0 (ru)
GR (1) GR851850B (ru)
HK (1) HK33289A (ru)
HU (1) HU201738B (ru)
IE (1) IE58122B1 (ru)
IL (1) IL75986A (ru)
IS (1) IS1430B6 (ru)
IT (1) IT1207325B (ru)
JO (1) JO1379B1 (ru)
KE (1) KE3858A (ru)
LU (2) LU88266I2 (ru)
MA (1) MA20499A1 (ru)
MX (2) MX159672A (ru)
NL (2) NL188642C (ru)
NO (2) NO164653C (ru)
NZ (1) NZ212948A (ru)
PH (2) PH22850A (ru)
PL (1) PL146005B1 (ru)
PT (1) PT80900B (ru)
SE (1) SE452460B (ru)
SK (1) SK404191A3 (ru)
SU (1) SU1498386A3 (ru)
UA (1) UA6329A1 (ru)
ZA (1) ZA855818B (ru)
ZW (1) ZW12485A1 (ru)

Families Citing this family (65)

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US5270333A (en) * 1986-01-28 1993-12-14 Glaxo Group Limited Indole derivatives
US5935925A (en) * 1990-05-08 1999-08-10 Synaptic Pharmaceutical Corporation Methods of treating migraine and compounds useful for such methods
US5155218A (en) * 1990-05-08 1992-10-13 Neurogenetic Corporation Dna encoding human 5-ht1d receptors
GB9013845D0 (en) * 1990-06-21 1990-08-15 Glaxo Group Ltd Process
GB9022250D0 (en) * 1990-10-12 1990-11-28 Glaxo Group Ltd Medicaments
GB9102579D0 (en) * 1991-01-24 1991-03-27 Glaxo Group Ltd Compositions
GB9101592D0 (en) * 1991-01-24 1991-03-06 Glaxo Group Ltd Compositions
CZ283018B6 (cs) * 1991-02-01 1997-12-17 Merck Sharp And Dohme Limited Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi
GB9104890D0 (en) 1991-03-08 1991-04-24 Glaxo Group Ltd Compositions
AT399870B (de) * 1991-06-06 1995-08-25 Vita Invest Sa Verfahren zur herstellung von 3-(2-(dimethylamino)ethyl)-n-methyl-1h-indol-5- ethansulfonamid
GB9209882D0 (en) * 1992-05-07 1992-06-24 Glaxo Lab Sa Compositions
ES2059236B1 (es) * 1992-06-18 1995-06-16 Imidex S A Procedimiento para la sintesis de la 3-(2-dimetilamino) etil)-n-metil-1h-indol-5-metanosulfonamida.
ES2055651B1 (es) * 1992-07-20 1995-03-01 Vita Invest Sa Procedimiento para la obtencion de nuevas amidinas derivadas de 3-aminoetilindoles.
IL106445A (en) * 1992-07-30 1998-01-04 Merck Sharp & Dohme History of 1,2,4-Trans-Triazole 4-Transform, Preparation and Pharmaceutical Preparations Containing Them
AT399871B (de) * 1993-02-15 1995-08-25 Vita Invest Sa Verfahren zur herstellung von 2-carboxy-3-(2- (dimethylamino)ethyl)-n-methyl-1h-indol-5- methansulfonamid und dessen niederalkylestern
US5807571A (en) * 1993-05-06 1998-09-15 Lts Lohmann Therapie-Systeme Gmbh Transdermal therapeutic systems for administering indole serotonin agonists
GB9401436D0 (en) * 1994-01-26 1994-03-23 Wellcome Found Therapeutic heterocyclic compounds
ES2084560B1 (es) * 1994-03-09 1997-01-16 Almirall Lab Procedimiento de preparacion de derivados el indol.
ES2079323B1 (es) * 1994-06-21 1996-10-16 Vita Invest Sa Derivados de indol utiles para el tratamiento de la migraña, composicion y uso correspondientes.
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US5521197A (en) 1994-12-01 1996-05-28 Eli Lilly And Company 3-<1-alkylenearyl>-4-<1,2,3,6-tetrahydropyridinyl>-and 3-<1-alkylenearyl>-4-piperidinyl-1h-indoles: new 5-HT1F agonists
US8022095B2 (en) 1996-08-16 2011-09-20 Pozen, Inc. Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
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GB9714383D0 (en) * 1997-07-08 1997-09-10 Pfizer Ltd Improved process
US6066092A (en) * 1997-11-06 2000-05-23 Cady; Roger K. Preemptive prophylaxis of migraine device and method
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
US6416472B1 (en) 1997-11-06 2002-07-09 Edus Inc. Method and device for measuring cognitive efficiency
AT500063A1 (de) * 1999-11-23 2005-10-15 Sandoz Ag Beschichtete tablettenkerne
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US8329734B2 (en) 2009-07-27 2012-12-11 Afgin Pharma Llc Topical therapy for migraine
FR2827287B1 (fr) * 2001-07-13 2003-10-31 Servier Lab Nouveaux derives de benzene sulfonamide, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN1649614A (zh) 2002-02-22 2005-08-03 新河药品股份有限公司 活性剂传递系统和保护及施用活性剂的方法
US20060106227A1 (en) * 2002-06-13 2006-05-18 Dr Reddy's Laboratories Limited 3-'2-(Dimethylamino) ethyl!-n-methyl-1h-indole-5-methanesulfonamide and the succinate thereof
US20040068000A1 (en) * 2002-10-02 2004-04-08 Mintong Guo Compression coated tablets
CN1176649C (zh) * 2002-10-16 2004-11-24 上海医药工业研究院 舒马普坦干粉吸入剂及其制备方法
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US20080213363A1 (en) * 2003-01-23 2008-09-04 Singh Nikhilesh N Methods and compositions for delivering 5-HT3 antagonists across the oral mucosa
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US20070054953A1 (en) * 2003-05-12 2007-03-08 Potluri Ramesh B A novel process for preparation of indole derivatives
BRPI0410807A (pt) * 2003-06-06 2006-06-27 Glaxo Group Ltd composição farmacêutica, e, método pata tratar um mamìfero sofrendo de ou susceptìvel a condições associadas com dor cefálica
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US7375219B2 (en) * 2005-04-13 2008-05-20 Neuraxon, Inc. Substituted indole compounds having NOS inhibitory activity
US20070166336A1 (en) * 2005-12-13 2007-07-19 David Delmarre Stable and palatable oral liquid sumatriptan compositions
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WO2009128089A2 (en) * 2008-02-11 2009-10-22 Matrix Laboratories Limited Novel solvate form of sumatriptan succinate and process for preparing sumatriptan salt employing the same
US20090252791A1 (en) * 2008-04-02 2009-10-08 Venkata Nookaraju Sreedharala Pharmaceutical compositions comprising a triptan and a nonsteroidal anti-inflammatory drug
KR101517415B1 (ko) * 2008-05-14 2015-05-07 에스케이바이오팜 주식회사 난용성 항경련제를 함유하는 경비 항경련성 약학 조성물
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CN102432520B (zh) * 2011-11-21 2013-10-09 山东新华制药股份有限公司 3-[2-（二甲氨基）乙基]-n-甲基吲哚-5-甲烷磺酰胺琥珀酸盐的制备方法
CN107530318A (zh) 2015-03-02 2018-01-02 阿福金制药有限责任公司 用大麻素的局部区域神经影响性疗法
US10383816B2 (en) 2015-03-02 2019-08-20 Afgin Pharma, Llc Topical regional neuro-affective therapy with cannabinoid combination products
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Also Published As

Publication number Publication date
SK277952B6 (en) 1995-09-13
NL930065I2 (nl) 1993-10-01
AU573878B2 (en) 1988-06-23
UA6329A1 (ru) 1994-12-29
ES545810A0 (es) 1986-10-16
MX14221A (es) 1993-10-01
HUT40077A (en) 1986-11-28
PL146005B1 (en) 1988-12-31
ZW12485A1 (en) 1986-02-26
SU1498386A3 (ru) 1989-07-30
NO164653C (no) 1990-11-07
NL930065I1 (nl) 1993-09-01
CH666026A5 (fr) 1988-06-30
FI78466B (fi) 1989-04-28
SE8503680L (sv) 1986-02-02
DK158942C (da) 1991-01-21
ES8801900A1 (es) 1988-03-01
FR2568571B1 (fr) 1988-09-23
IS1430B6 (is) 1990-07-16
DK351185A (da) 1986-02-02
PT80900B (pt) 1987-12-30
IE851918L (en) 1986-02-01
ES8700234A1 (es) 1986-10-16
BE903006A (fr) 1986-02-03
MX159672A (es) 1989-08-02
AT386196B (de) 1988-07-11
HU201738B (en) 1990-12-28
NL8502171A (nl) 1986-03-03
ES552047A0 (es) 1987-12-16
DK351185D0 (da) 1985-08-01
SE8503680D0 (sv) 1985-08-01
GR851850B (ru) 1985-11-26
KR930003759B1 (ko) 1993-05-10
FI852969A0 (fi) 1985-08-01
IL75986A0 (en) 1985-12-31
NO1994023I1 (no) 1994-11-09
KE3858A (en) 1989-06-02
PT80900A (en) 1985-09-01
ES8801790A1 (es) 1988-02-16
NO853046L (no) 1986-02-03
FR2568571A1 (fr) 1986-02-07
CZ280530B6 (cs) 1996-02-14
ECSP941096A (es) 1995-01-16
CZ404191A3 (en) 1993-04-14
SE452460B (sv) 1987-11-30
MA20499A1 (fr) 1986-04-01
DE3527648A1 (de) 1986-02-13
NZ212948A (en) 1989-05-29
NL188642C (nl) 1992-08-17
ES557481A0 (es) 1988-02-16
LU86032A1 (fr) 1986-02-18
IT1207325B (it) 1989-05-17
ES557483A0 (es) 1988-02-16
EG17283A (en) 1992-06-30
FI78466C (fi) 1989-08-10
GB8419575D0 (en) 1984-09-05
FI852969L (fi) 1986-02-02
AU4568985A (en) 1986-02-06
IL75986A (en) 1989-02-28
DK158942B (da) 1990-08-06
HK33289A (en) 1989-04-28
PH24117A (en) 1990-03-05
NO164653B (no) 1990-07-23
DOP1989004759A (es) 1999-02-06
KR860001788A (ko) 1986-03-22
PH22850A (en) 1989-01-19
SK404191A3 (en) 1995-09-13
JPH0623197B2 (ja) 1994-03-30
ZA855818B (en) 1986-04-30
ES8801789A1 (es) 1988-02-16
ES557482A0 (es) 1988-03-01
ES557480A0 (es) 1988-02-16
IE58122B1 (en) 1993-07-14
JPS6147464A (ja) 1986-03-07
IT8548435A0 (it) 1985-08-01
JO1379B1 (en) 1986-11-30
ES8801788A1 (es) 1988-02-16
ATA226685A (de) 1987-12-15
CA1241004A (en) 1988-08-23
US5037845A (en) 1991-08-06
ES8801204A1 (es) 1987-12-16
IS3034A7 (is) 1986-02-02
PL254800A1 (en) 1986-10-21
DE3527648C2 (ru) 1993-08-26

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