LU84717A1 - Nouveaux derives de cephalosporine,leur procede de production et composition pharmaceutique les contenant - Google Patents

Nouveaux derives de cephalosporine,leur procede de production et composition pharmaceutique les contenant Download PDF

Info

Publication number
LU84717A1
LU84717A1 LU84717A LU84717A LU84717A1 LU 84717 A1 LU84717 A1 LU 84717A1 LU 84717 A LU84717 A LU 84717A LU 84717 A LU84717 A LU 84717A LU 84717 A1 LU84717 A1 LU 84717A1
Authority
LU
Luxembourg
Prior art keywords
methyl
cephem
compound
ethyl
carboxylate
Prior art date
Application number
LU84717A
Other languages
English (en)
French (fr)
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of LU84717A1 publication Critical patent/LU84717A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
LU84717A 1982-03-29 1983-03-28 Nouveaux derives de cephalosporine,leur procede de production et composition pharmaceutique les contenant LU84717A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36331382 1982-03-29
US06/363,313 US4457929A (en) 1982-03-29 1982-03-29 3-Quaternary ammonium methyl)-substituted cephalosporin derivatives

Publications (1)

Publication Number Publication Date
LU84717A1 true LU84717A1 (fr) 1983-12-05

Family

ID=23429716

Family Applications (1)

Application Number Title Priority Date Filing Date
LU84717A LU84717A1 (fr) 1982-03-29 1983-03-28 Nouveaux derives de cephalosporine,leur procede de production et composition pharmaceutique les contenant

Country Status (33)

Country Link
US (1) US4457929A (da)
JP (1) JPS58198490A (da)
KR (1) KR900005047B1 (da)
AT (1) AT383129B (da)
AU (1) AU564971B2 (da)
BE (1) BE896292A (da)
CA (1) CA1213883A (da)
CH (1) CH655118A5 (da)
CS (1) CS264257B2 (da)
DD (1) DD210279A5 (da)
DE (1) DE3311300A1 (da)
DK (1) DK161024C (da)
EG (1) EG16029A (da)
ES (2) ES520983A0 (da)
FI (1) FI74974C (da)
FR (1) FR2523973B1 (da)
GB (1) GB2117770B (da)
GR (1) GR77907B (da)
HU (1) HU189676B (da)
IE (1) IE54791B1 (da)
IL (1) IL68244A0 (da)
IT (1) IT1164634B (da)
LU (1) LU84717A1 (da)
MY (1) MY8700944A (da)
NL (1) NL8301053A (da)
NZ (1) NZ203360A (da)
OA (1) OA07354A (da)
PH (1) PH18959A (da)
PT (1) PT76460B (da)
SE (1) SE453092B (da)
SU (3) SU1205772A3 (da)
YU (1) YU43654B (da)
ZA (1) ZA832156B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963542A (en) * 1976-09-08 1990-10-16 Takeda Chemical Industries, Ltd. Cephalosporin derivatives
US6099850A (en) * 1981-10-26 2000-08-08 Battelle Memorial Institute Termite and boring insect barrier for the protection of wooden structures
US6060076A (en) * 1981-10-26 2000-05-09 Battelle Memorial Institute Method and apparatus for providing long term protection from intrusion by insects and other cold blooded animals
US6331308B1 (en) 1981-10-26 2001-12-18 Battelle Memorial Institute Method and apparatus for providing long term protection from intrusion by insects and other cold blooded animals
US5925368A (en) * 1981-10-26 1999-07-20 Battelle Memorial Institute Protection of wooden objects in direct contact with soil from pest invasion
US4525473A (en) * 1983-03-30 1985-06-25 Bristol-Myers Company Cephalosporins
DE3409431A1 (de) * 1983-10-08 1985-04-18 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3419012A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel oder wachstumsfoerderer in der tieraufzucht oder als antioxidantien
GB8424692D0 (en) * 1984-10-01 1984-11-07 Glaxo Group Ltd Chemical compounds
EP0182210B1 (en) * 1984-11-12 1991-02-27 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives
US4868173A (en) * 1984-11-20 1989-09-19 Ici Pharma Cephalosporin derivatives
US4883868A (en) * 1984-12-27 1989-11-28 Banyu Pharmaceutical Co., Ltd. 7-amino-3-(substituted isoindolinium)methyl-3-cephem derivatives
JPH068300B2 (ja) * 1985-08-02 1994-02-02 萬有製薬株式会社 新規セフアロスポリン誘導体
IE862850L (en) * 1985-11-21 1987-05-21 Inst Animal Health Ltd Intermediates for the preparation of beta-lactam antibiotics
US4814328A (en) * 1986-03-19 1989-03-21 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, and antibacterial agents
IL84128A (en) * 1986-10-13 1992-12-01 Eisai Co Ltd 3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them
US5244890A (en) * 1988-06-06 1993-09-14 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US6319511B1 (en) 1989-09-01 2001-11-20 Battelle Memorial Institute Termite and boring insect barrier for the protection of wooden structures
US6572872B2 (en) 1989-09-01 2003-06-03 Battelle Memorial Institute Method and apparatus for providing long term protection from intrusion by insects and other cold blooded animals
US6852328B1 (en) 1989-09-01 2005-02-08 Battelle Memorial Institute K1-53 Method and device for protection of wooden objects proximate soil from pest invasion
GB9107973D0 (en) * 1991-04-15 1991-05-29 Fujisawa Pharmaceutical Co New cephem compounds and process for preparation thereof
US5985304A (en) 1998-02-25 1999-11-16 Battelle Memorial Institute Barrier preventing wood pest access to wooden structures
KR100380323B1 (ko) * 2000-01-26 2003-04-16 한국과학기술연구원 Ｎ-메틸-ｎ-(3-메틸-1,3-티아졸리움-2-일)아미노기를함유한 신규한 세팔로스포린 화합물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
GR63088B (en) * 1976-04-14 1979-08-09 Takeda Chemical Industries Ltd Preparation process of novel cephalosporins
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
AU529823B2 (en) * 1978-10-26 1983-06-23 Glaxo Group Limited Cephalosporin compounds
ES485433A1 (es) * 1978-10-27 1980-07-01 Glaxo Group Ltd Un procedimiento para la preparacion de antibioticos de ce- falosporina
GR78245B (da) * 1980-09-12 1984-09-26 Ciba Geigy Ag

Also Published As

Publication number Publication date
IL68244A0 (en) 1983-06-15
DK95383A (da) 1983-09-30
ZA832156B (en) 1984-08-29
DE3311300A1 (de) 1983-09-29
SU1313351A3 (ru) 1987-05-23
ATA110983A (de) 1986-10-15
ES527661A0 (es) 1985-04-16
FR2523973B1 (fr) 1986-09-12
CS264257B2 (en) 1989-06-13
FI74974B (fi) 1987-12-31
ES8504205A1 (es) 1985-04-16
CH655118A5 (de) 1986-03-27
FI831013L (fi) 1983-09-30
GB2117770B (en) 1985-10-09
EG16029A (en) 1987-03-30
JPS58198490A (ja) 1983-11-18
OA07354A (fr) 1984-08-31
PH18959A (en) 1985-11-26
DD210279A5 (de) 1984-06-06
AT383129B (de) 1987-05-25
SU1205772A3 (ru) 1986-01-15
DK161024B (da) 1991-05-21
US4457929A (en) 1984-07-03
AU564971B2 (en) 1987-09-03
GR77907B (da) 1984-09-25
IT1164634B (it) 1987-04-15
CS219083A2 (en) 1988-09-16
GB8308519D0 (en) 1983-05-05
HU189676B (en) 1986-07-28
SE453092B (sv) 1988-01-11
BE896292A (fr) 1983-09-28
KR840004119A (ko) 1984-10-06
DE3311300C2 (da) 1991-05-16
SE8301726D0 (sv) 1983-03-28
KR900005047B1 (ko) 1990-07-18
SE8301726L (sv) 1983-11-25
SU1373325A3 (ru) 1988-02-07
DK95383D0 (da) 1983-02-25
YU43654B (en) 1989-10-31
MY8700944A (en) 1987-12-31
IE830687L (en) 1983-09-29
FI74974C (fi) 1988-04-11
ES8600312A1 (es) 1985-10-01
PT76460A (en) 1983-04-01
AU1186483A (en) 1983-10-06
IE54791B1 (en) 1990-02-14
FI831013A0 (fi) 1983-03-24
ES520983A0 (es) 1985-10-01
IT8348006A0 (it) 1983-03-28
NZ203360A (en) 1985-08-16
CA1213883A (en) 1986-11-12
YU71683A (en) 1986-02-28
NL8301053A (nl) 1983-10-17
GB2117770A (en) 1983-10-19
DK161024C (da) 1991-10-28
PT76460B (en) 1986-03-11
FR2523973A1 (fr) 1983-09-30

Similar Documents

Publication Publication Date Title
LU84717A1 (fr) Nouveaux derives de cephalosporine,leur procede de production et composition pharmaceutique les contenant
FR2540875A1 (fr) Nouveaux derives de la cephalosporine et leur procede de preparation
FR2512449A1 (fr) Quinoleinium-betaines de cephalosporine et leur application pharmacolique
JPH0314039B2 (da)
EP0462009B1 (fr) Céphalosporines comportant en position 3 un radical propényle substitué par un ammonium quaternaire, leur procédé de préparation, leur application comme médicaments, les compositions les renfermant et les intermédiaires obtenus
BE897864A (fr) Procede de production de composes de 3-vinyl-3-cephem 7-substitues et nouveaux produits ainsi obtenus
FR2522659A1 (fr) Nouveaux derives de cephalosporine, leur procede de preparation et composition anti-bacterienne les contenant
FR2517308A1 (fr) Procede de preparation de derives de 3-alcoxymethylcephalosporines
FR2569195A1 (fr) Derives du 7-carboxymethoxyphenylacetamido-3-cepheme utiles comme medicaments antibacteriens et procedes pour leur preparation
EP0060745A2 (fr) Nouveaux dérivés antibiotiques dérivés des céphalosporines
CH635846A5 (fr) Antibiotiques de cephalosporine a large spectre.
LU86488A1 (fr) Acides propenylaminothiazolylcephalosporaniques 3-substitues et leurs esters
BE875054A (fr) Composes analogues aux cephalosporines
JPH02138283A (ja) ７‐アミノチアゾリルアセトアミドセファロスポラン酸の新規な０‐置換オキシム誘導体
BE833063A (fr) N - acylamino - alpha - arylacetamido - cephalosporines
CA1140113A (fr) Procede de preparation de nouvelles oximes 0-substituees par un radical comportant un ammonium quatermaire et derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique
BE880037A (fr) Cephalosporines a activite antibiotique et procede de preparation
FR2564095A1 (fr) Antibiotiques de cephalosporine, leur preparation et compositions pharmaceutiques les contenant
FR2571056A1 (fr) Derives de cephalosporine et leur procede de preparation
BE882359A (fr) Antibiotiques du type cephalosporine et procede de preparation
FR2485540A1 (fr) Nouveaux derives antibiotiques des cephalosporines, leur procede de preparation et les medicaments en contenant
FR2529555A1 (fr) Cephalosporines a activite antibiotique, leur procede de preparation et leur application en therapeutique
FR2498189A1 (fr) Nouveaux derives de l'acide cephalosporanique, leur preparation et leur application comme medicaments
FR2536074A1 (fr) Nouvelles cephalosporines, procedes pour les preparer, agents antibacteriens les contenant, intermediaires pour leur preparation, et procede de preparation des intermediaires
LU85101A1 (fr) Antibiotiques du genre des cephalosporines